Found: 56
Select item for more details and to access through your institution.
Safety and pharmacokinetic study of nab-paclitaxel plus carboplatin in chemotherapy-naïve patients with advanced non-small cell lung cancer.
- Published in:
- 2012
- By:
- Publication type:
- Journal Article
Results of a phase II trial of S-1 as first-line treatment of metastatic pancreatic cancer (CESAR-study group)
- Published in:
- 2012
- By:
- Publication type:
- Journal Article
Further developments for improving response and tolerance to irradiation for advanced renal cancer: concurrent (mTOR) inhibitor RAD001 and helical tomotherapy.
- Published in:
- 2012
- By:
- Publication type:
- Report
Phase II study of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1138, doi. 10.1007/s10637-010-9619-8
- By:
- Publication type:
- Article
Inhibition of TGF-[beta] signaling, vasculogenic mimicry and proinflammatory gene expression by isoxanthohumol.
- Published in:
- 2012
- By:
- Publication type:
- Journal Article
Everolimus-related organizing pneumonia: a report establishing causality.
- Published in:
- 2012
- By:
- Publication type:
- Report
TRAIL shows potential cardioprotective activity.
- Published in:
- 2012
- By:
- Publication type:
- Report
Phase I study of continuous MKC-1 in patients with advanced or metastatic solid malignancies using the modified Time-to-Event Continual Reassessment Method (TITE-CRM) dose escalation design.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1039, doi. 10.1007/s10637-010-9629-6
- By:
- Publication type:
- Article
Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 853, doi. 10.1007/s10637-010-9622-0
- By:
- Publication type:
- Article
Antimetastatic activity and low systemic toxicity of tetradecyl gallate in a preclinical melanoma mouse model.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 870, doi. 10.1007/s10637-010-9628-7
- By:
- Publication type:
- Article
Irinotecan and DNA-PKcs inhibitors synergize in killing of colon cancer cells.
- Published in:
- 2012
- By:
- Publication type:
- Report
Caspase-independent apoptosis induction of quorum-sensing autoinducer analogs against chronic myeloid leukemia K562.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 862, doi. 10.1007/s10637-010-9623-z
- By:
- Publication type:
- Article
Phase 1 study of the novel vascular disrupting agent plinabulin (NPI-2358) and docetaxel.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1065, doi. 10.1007/s10637-011-9642-4
- By:
- Publication type:
- Article
A randomized phase II study of recombinant human endostatin plus gemcitabine/cisplatin compared with gemcitabine/cisplatin alone as first-line therapy in advanced non-small-cell lung cancer.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1144, doi. 10.1007/s10637-011-9631-7
- By:
- Publication type:
- Article
Sorafenib versus cytotoxic chemotherapy for patients with advanced hepatocellular carcinoma: a retrospective, single-institution study.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1150, doi. 10.1007/s10637-011-9634-4
- By:
- Publication type:
- Article
Progression-free survival and time to progression as surrogate markers of overall survival in patients with advanced gastric cancer: analysis of 36 randomized trials.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1224, doi. 10.1007/s10637-011-9648-y
- By:
- Publication type:
- Article
A cytotoxic ribonuclease reduces the expression level of P-glycoprotein in multidrug-resistant cell lines.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 880, doi. 10.1007/s10637-011-9636-2
- By:
- Publication type:
- Article
Phase I trial of sorafenib in combination with interferon-alpha in Japanese patients with unresectable or metastatic renal cell carcinoma.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1046, doi. 10.1007/s10637-010-9630-0
- By:
- Publication type:
- Article
In vitro antitumor mechanism of a novel cyclin-dependent kinase inhibitor CDKI-83.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 889, doi. 10.1007/s10637-011-9641-5
- By:
- Publication type:
- Article
Hepatic arterial infusion (HAI) with PEGylated liposomes containing 5-FU improves tumor control of liver metastases in a rat model.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 927, doi. 10.1007/s10637-011-9646-0
- By:
- Publication type:
- Article
Management of axitinib (AG-013736)-induced fatigue and thyroid dysfunction, and predictive biomarkers of axitinib exposure: results from phase I studies in Japanese patients.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1055, doi. 10.1007/s10637-011-9637-1
- By:
- Publication type:
- Article
Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 916, doi. 10.1007/s10637-011-9645-1
- By:
- Publication type:
- Article
Targeting angiogenesis from multiple pathways simultaneously: BIBF 1120, an investigational novel triple angiokinase inhibitor.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1261, doi. 10.1007/s10637-011-9644-2
- By:
- Publication type:
- Article
Clinical and pharmacologic evaluation of two dose levels of intetumumab (CNTO 95) in patients with melanoma or angiosarcoma.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1074, doi. 10.1007/s10637-011-9639-z
- By:
- Publication type:
- Article
Inhibition of TGF-β signaling, vasculogenic mimicry and proinflammatory gene expression by isoxanthohumol.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 898, doi. 10.1007/s10637-011-9643-3
- By:
- Publication type:
- Article
Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potency in the acute myelogenous leukemia-Flt-3-internal tandem duplication mutant human tumor xenograft model.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 936, doi. 10.1007/s10637-011-9640-6
- By:
- Publication type:
- Article
Cell cycle arrest through inhibition of tubulin polymerization by withaphysalin F, a bioactive compound isolated from Acnistus arborescens.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 959, doi. 10.1007/s10637-011-9649-x
- By:
- Publication type:
- Article
Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 967, doi. 10.1007/s10637-011-9655-z
- By:
- Publication type:
- Article
In vivo toxicity study of N-1-sulfonylcytosine derivatives and their mechanisms of action in cervical carcinoma cell line.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 981, doi. 10.1007/s10637-011-9657-x
- By:
- Publication type:
- Article
A phase I trial of vandetanib combined with capecitabine, oxaliplatin and bevacizumab for the first-line treatment of metastatic colorectal cancer.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1082, doi. 10.1007/s10637-011-9656-y
- By:
- Publication type:
- Article
DNA interstrand cross-linking and in vivo antitumor activity of the extended pyrrolo[2,1- c][1,4]benzodiazepine dimer SG2057.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 950, doi. 10.1007/s10637-011-9647-z
- By:
- Publication type:
- Article
A randomized phase II of gemcitabine and sorafenib versus sorafenib alone in patients with metastatic pancreatic cancer.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1175, doi. 10.1007/s10637-011-9658-9
- By:
- Publication type:
- Article
A phase II trial of the Src kinase inhibitor saracatinib (AZD0530) in patients with metastatic or locally advanced gastric or gastro esophageal junction (GEJ) adenocarcinoma: a trial of the PMH phase II consortium.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1158, doi. 10.1007/s10637-011-9650-4
- By:
- Publication type:
- Article
A phase II trial of erlotinib in combination with gemcitabine and capecitabine in previously untreated metastatic/recurrent pancreatic cancer: combined analysis with translational research.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1164, doi. 10.1007/s10637-011-9651-3
- By:
- Publication type:
- Article
A phase I trial of MK-0731, a Kinesin Spindle Protein (KSP) inhibitor, in patients with solid tumors.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1088, doi. 10.1007/s10637-011-9653-1
- By:
- Publication type:
- Article
Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 991, doi. 10.1007/s10637-011-9654-0
- By:
- Publication type:
- Article
Aminopyrimidoisoquinolinequinone (APIQ) redox cycling is potentiated by ascorbate and induces oxidative stress leading to necrotic-like cancer cell death.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1003, doi. 10.1007/s10637-011-9661-1
- By:
- Publication type:
- Article
Results of a phase II trial of S-1 as first-line treatment of metastatic pancreatic cancer (CESAR-study group).
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1184, doi. 10.1007/s10637-011-9665-x
- By:
- Publication type:
- Article
A phase I study of oral panobinostat (LBH589) in Japanese patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1096, doi. 10.1007/s10637-011-9666-9
- By:
- Publication type:
- Article
A retrospective pooled analysis of trabectedin safety in 1,132 patients with solid tumors treated in phase II clinical trials.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1193, doi. 10.1007/s10637-011-9662-0
- By:
- Publication type:
- Article
A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1012, doi. 10.1007/s10637-011-9668-7
- By:
- Publication type:
- Article
Phase I/II multicenter study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD4877 in patients with refractory acute myeloid leukemia.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1107, doi. 10.1007/s10637-011-9660-2
- By:
- Publication type:
- Article
Multifunctional 5-aminolevulinic acid prodrugs activating diverse cell-death pathways.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1028, doi. 10.1007/s10637-011-9669-6
- By:
- Publication type:
- Article
The fate of camptothecin glycoconjugate: report of a clinical hold during a phase II study of BAY 56-3722 (formerly BAY 38-3441), in patients with recurrent or metastatic colorectal cancer resistant/refractory to irinotecan.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1208, doi. 10.1007/s10637-011-9679-4
- By:
- Publication type:
- Article
A Phase III trial of fludarabine, cyclophosphamide, and rituximab vs. pentostatin, cyclophosphamide, and rituximab in B-cell chronic lymphocytic leukemia.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1232, doi. 10.1007/s10637-011-9737-y
- By:
- Publication type:
- Article
A phase II study of the halichondrin B analog eribulin mesylate in gemcitabine refractory advanced pancreatic cancer.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1203, doi. 10.1007/s10637-011-9673-x
- By:
- Publication type:
- Article
Safety and pharmacokinetic study of nab-paclitaxel plus carboplatin in chemotherapy-naïve patients with advanced non-small cell lung cancer.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1132, doi. 10.1007/s10637-011-9674-9
- By:
- Publication type:
- Article
Reappraisal of treatment-induced renal dysfunction in patients receiving antiangiogenic agents in phase I trials.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1116, doi. 10.1007/s10637-011-9671-z
- By:
- Publication type:
- Article
Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 3, p. 1121, doi. 10.1007/s10637-011-9670-0
- By:
- Publication type:
- Article
Erratum to: Phase I trial of sorafenib in combination with interferon-alpha in Japanese patients with unresectable or metastatic renal cell carcinoma.
- Published in:
- 2012
- By:
- Publication type:
- Correction notice