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Judith James honored with the 2020 Stanley J. Korsmeyer Award.
Published in:
2020
By:
- Jackson, Sarah
Publication type:
journal article
The convalescent sera option for containing COVID-19.
Published in:
Journal of Clinical Investigation, 2020, v. 130, n. 4, p. 1545, doi. 10.1172/JCI138003
By:
- Casadevall, Arturo;
- Pirofski, Liise-anne
Publication type:
Article
Alternative therapies in academic medical centers compromise evidence-based patient care.
Published in:
2020
By:
- Marcus, Donald M.
Publication type:
journal article
One-two punch injury to tolerance mechanisms in graft-versus-host disease.
Published in:
2020
By:
- Carrington, Léolène J.;
- Maillard, Ivan
Publication type:
journal article
Platelets: inflammatory effector cells in the conflagration of cystic fibrosis lung disease.
Published in:
2020
By:
- Zimmerman, Guy A.
Publication type:
journal article
Intrinsic antiviral immunity drives neurodegeneration in Alzheimer disease.
Published in:
2020
By:
- Pluchino, Stefano;
- Willis, Cory
Publication type:
journal article
The gift of a lifetime: analysis of HIV at autopsy.
Published in:
2020
By:
- Maldarelli, Frank
Publication type:
journal article
CoRESTed development of regulatory T cells.
Published in:
2020
By:
- Morales-Nebreda, Luisa;
- Helmin, Kathryn A.;
- Singer, Benjamin D.
Publication type:
journal article
The microbiome adds to the complexity of parathyroid hormone action on bone.
Published in:
2020
By:
- Khosla, Sundeep
Publication type:
journal article
c-Maf: a bad influence in the education of macrophages.
Published in:
2020
By:
- Conejo-Garcia, Jose R.;
- Rodriguez, Paulo C.
Publication type:
journal article
Parathyroid hormone-dependent bone formation requires butyrate production by intestinal microbiota.
Published in:
2020
By:
- Jau-Yi Li;
- Mingcan Yu;
- Pal, Subhashis;
- Tyagi, Abdul Malik;
- Dar, Hamid;
- Adams, Jonathan;
- Weitzmann, M. Neale;
- Jones, Rheinallt M.;
- Pacifici, Roberto;
- Li, Jau-Yi;
- Yu, Mingcan
Publication type:
journal article
Enasidenib drives human erythroid differentiation independently of isocitrate dehydrogenase 2.
Published in:
2020
By:
- Dutta, Ritika;
- Tian Yi Zhang;
- Köhnke, Thomas;
- Thomas, Daniel;
- Linde, Miles;
- Gars, Eric;
- Stafford, Melissa;
- Kaur, Satinder;
- Nakauchi, Yusuke;
- Yin, Raymond;
- Azizi, Armon;
- Narla, Anupama;
- Majeti, Ravindra;
- Zhang, Tian Yi
Publication type:
journal article
Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration.
Published in:
2020
By:
- Charish, Jason;
- Shabanzadeh, Alireza P.;
- Danian Chen;
- Mehlen, Patrick;
- Sethuramanujam, Santhosh;
- Harada, Hidekiyo;
- Bonilha, Vera L.;
- Awatramani, Gautam;
- Bremner, Rod;
- Monnier, Philippe P.;
- Chen, Danian
Publication type:
journal article
Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity.
Published in:
2020
By:
- Yan Xiong;
- Liqing Wang;
- Di Giorgio, Eros;
- Akimova, Tatiana;
- Beier, Ulf H.;
- Rongxiang Han;
- Trevisanut, Matteo;
- Kalin, Jay H.;
- Cole, Philip A.;
- Hancock, Wayne W.;
- Xiong, Yan;
- Wang, Liqing;
- Han, Rongxiang
Publication type:
journal article
A role for connexin-43 in Duchenne muscular dystrophy cardiomyopathy.
Published in:
2020
By:
- Shaw, Robin M.;
- Saffitz, Jeffrey E.
Publication type:
journal article
Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer.
Published in:
2020
By:
- Yadong Xie;
- Yifan Zhao;
- Lei Shi;
- Wei Li;
- Kun Chen;
- Min Li;
- Xia Chen;
- Haiwei Zhang;
- Tiantian Li;
- Yu Matsuzawa-Ishimoto;
- Xiaomin Yao;
- Dianhui Shao;
- Zunfu Ke;
- Jian Li;
- Yan Chen;
- Xiaoming Zhang;
- Jun Cui;
- Shuzhong Cui;
- Qibin Leng;
- Ken Cadwell
Publication type:
journal article
HIV persists throughout deep tissues with repopulation from multiple anatomical sources.
Published in:
2020
By:
- Chaillon, Antoine;
- Gianella, Sara;
- Dellicour, Simon;
- Rawlings, Stephen A.;
- Schlub, Timothy E.;
- De Oliveira, Michelli Faria;
- Ignacio, Caroline;
- Porrachia, Magali;
- Vrancken, Bram;
- Smith, Davey M.
Publication type:
journal article
Leptin mediates postprandial increases in body temperature through hypothalamus-adrenal medulla-adipose tissue crosstalk.
Published in:
2020
By:
- Perry, Rachel J.;
- Kun Lyu;
- Rabin-Court, Aviva;
- Jianying Dong;
- Xiruo Li;
- Yunfan Yang;
- Hua Qing;
- Wang, Andrew;
- Xiaoyong Yang;
- Shulman, Gerald I.;
- Lyu, Kun;
- Dong, Jianying;
- Li, Xiruo;
- Yang, Yunfan;
- Qing, Hua;
- Yang, Xiaoyong
Publication type:
journal article
High residual C-peptide likely contributes to glycemic control in type 1 diabetes.
Published in:
2020
By:
- Rickels, Michael R.;
- Evans-Molina, Carmella;
- Bahnson, Henry T.;
- Ylescupidez, Alyssa;
- Nadeau, Kristen J.;
- Wei Hao;
- Clements, Mark A.;
- Sherr, Jennifer L.;
- Pratley, Richard E.;
- Hannon, Tamara S.;
- Shah, Viral N.;
- Miller, Kellee M.;
- Greenbaum, Carla J.;
- Hao, Wei;
- T1D Exchange β-Cell Function Study Group
Publication type:
journal article
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease.
Published in:
2020
By:
- Roy, Ethan R.;
- Wang, Baiping;
- Ying-wooi Wan;
- Chiu, Gabriel;
- Cole, Allysa;
- Zhuoran Yin;
- Propson, Nicholas E.;
- Yin Xu;
- Jankowsky, Joanna L.;
- Zhandong Liu;
- Lee, Virginia M.-Y.;
- Trojanowski, John Q.;
- Ginsberg, Stephen D.;
- Butovsky, Oleg;
- Hui Zheng;
- Wei Cao;
- Wan, Ying-Wooi;
- Yin, Zhuoran;
- Xu, Yin;
- Liu, Zhandong
Publication type:
journal article
Graft-versus-host disease reduces lymph node display of tissue-restricted self-antigens and promotes autoimmunity.
Published in:
2020
By:
- Dertschnig, Simone;
- Evans, Pamela;
- Santos e Sousa, Pedro;
- Manzo, Teresa;
- Ferrer, Ivana R.;
- Stauss, Hans J.;
- Bennett, Clare L.;
- Chakraverty, Ronjon
Publication type:
journal article
Steroid resistance in Diamond Blackfan anemia associates with p57Kip2 dysregulation in erythroid progenitors.
Published in:
2020
By:
- Ashley, Ryan J.;
- Hongxia Yan;
- Nan Wang;
- Hale, John;
- Dulmovits, Brian M.;
- Papoin, Julien;
- Olive, Meagan E.;
- Udeshi, Namrata D.;
- Carr, Steven A.;
- Vlachos, Adrianna;
- Lipton, Jeffrey M.;
- Da Costa, Lydie;
- Hillyer, Christopher;
- Kinet, Sandrina;
- Taylor, Naomi;
- Mohandas, Narla;
- Narla, Anupama;
- Blanc, Lionel;
- Yan, Hongxia;
- Wang, Nan
Publication type:
journal article
Genomics of lethal prostate cancer at diagnosis and castration resistance.
Published in:
2020
By:
- Mateo, Joaquin;
- Seed, George;
- Bertan, Claudia;
- Rescigno, Pasquale;
- Dolling, David;
- Figueiredo, Ines;
- Miranda, Susana;
- Rodrigues, Daniel Nava;
- Gurel, Bora;
- Clarke, Matthew;
- Atkin, Mark;
- Chandler, Rob;
- Messina, Carlo;
- Sumanasuriya, Semini;
- Bianchini, Diletta;
- Barrero, Maialen;
- Petermolo, Antonella;
- Zafeiriou, Zafeiris;
- Fontes, Mariane;
- Perez-Lopez, Raquel
Publication type:
journal article
Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer.
Published in:
2020
By:
- Min Liu;
- Zan Tong;
- Chuanlin Ding;
- Fengling Luo;
- Shouzhen Wu;
- Caijun Wu;
- Albeituni, Sabrin;
- Liqing He;
- Xiaoling Hu;
- Tieri, David;
- Rouchka, Eric C.;
- Michito Hamada;
- Satoru Takahashi;
- Gibb, Andrew A.;
- Goetz Kloecker;
- Huang-ge Zhang;
- Michael Bousamra II;
- Bradford G. Hill;
- Xiang Zhang;
- Jun Yan
Publication type:
journal article
Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation.
Published in:
2020
By:
- de Oliveira, Cristiane;
- Khatua, Biswajit;
- Noel, Pawan;
- Kostenko, Sergiy;
- Bag, Arup;
- Balakrishnan, Bijinu;
- Patel, Krutika S.;
- Guerra, Andre A.;
- Martinez, Melissa N.;
- Trivedi, Shubham;
- McCullough, Ann;
- Lam-Himlin, Dora M.;
- Navina, Sarah;
- Faigel, Douglas O.;
- Fukami, Norio;
- Pannala, Rahul;
- Phillips, Anna Evans;
- Papachristou, Georgios I.;
- Kershaw, Erin E.;
- Lowe, Mark E.
Publication type:
journal article
Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.
Published in:
2020
By:
- Jeongeun Hyun;
- Zhaoli Sun;
- Ahmadi, Ali Reza;
- Bangru, Sushant;
- Chembazhi, Ullas V.;
- Kuo Du;
- Tianyi Chen;
- Hidekazu Tsukamoto;
- Rusyn, Ivan;
- Kalsotra, Auinash;
- Diehl, Anna Mae;
- Hyun, Jeongeun;
- Sun, Zhaoli;
- Du, Kuo;
- Chen, Tianyi;
- Tsukamoto, Hidekazu
Publication type:
journal article
State of the art in CAR T cell therapy for CD19+ B cell malignancies.
Published in:
2020
By:
- Frigault, Matthew J.;
- Maus, Marcela V.
Publication type:
journal article
Capsular glycan recognition provides antibody-mediated immunity against tuberculosis.
Published in:
2020
By:
- Tingting Chen;
- Blanc, Caroline;
- Yanyan Liu;
- Ishida, Elise;
- Singer, Sarah;
- Jiayong Xu;
- Joe, Maju;
- Jenny-Avital, Elizabeth R.;
- Chan, John;
- Lowary, Todd L.;
- Achkar, Jacqueline M.;
- Chen, Tingting;
- Liu, Yanyan;
- Xu, Jiayong
Publication type:
journal article
An endocannabinoid-regulated basolateral amygdala-nucleus accumbens circuit modulates sociability.
Published in:
2020
By:
- Folkes, Oakleigh M.;
- Báldi, Rita;
- Kondev, Veronika;
- Marcus, David J.;
- Hartley, Nolan D.;
- Turner, Brandon D.;
- Ayers, Jade K.;
- Baechle, Jordan J.;
- Misra, Maya P.;
- Altemus, Megan;
- Grueter, Carrie A.;
- Grueter, Brad A.;
- Patel, Sachin
Publication type:
journal article
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity.
Published in:
2020
By:
- Webb, Lindsay M.;
- Sengupta, Shouvonik;
- Edell, Claudia;
- Piedra-Quintero, Zayda L.;
- Amici, Stephanie A.;
- Miranda, Janiret Narvaez;
- Bevins, Makenzie;
- Kennemer, Austin;
- Laliotis, Georgios;
- Tsichlis, Philip N.;
- Guerau-de-Arellano, Mireia
Publication type:
journal article
Genome-wide plasma DNA methylation features of metastatic prostate cancer.
Published in:
2020
By:
- Anjui Wu;
- Cremaschi, Paolo;
- Wetterskog, Daniel;
- Conteduca, Vincenza;
- Franceschini, Gian Marco;
- Kleftogiannis, Dimitrios;
- Jayaram, Anuradha;
- Sandhu, Shahneen;
- Wong, Stephen Q.;
- Benelli, Matteo;
- Salvi, Samanta;
- Gurioli, Giorgia;
- Feber, Andrew;
- Buongermino Pereira, Mariana;
- Wingate, Anna Maria;
- Gonzalez-Billalebeitia, Enrique;
- De Giorgi, Ugo;
- Demichelis, Francesca;
- Lise, Stefano;
- Attard, Gerhardt
Publication type:
journal article
Ubiquitous antigen-specific T regulatory type 1 cells variably suppress hepatic and extrahepatic autoimmunity.
Published in:
2020
By:
- Umeshappa, Channakeshava Sokke;
- Mbongue, Jacques;
- Singha, Santiswarup;
- Mohapatra, Saswat;
- Yamanouchi, Jun;
- Lee, Justin A.;
- Nanjundappa, Roopa Hebbandi;
- Kun Shao;
- Christen, Urs;
- Yang Yang;
- Ellestad, Kristofor K.;
- Santamaria, Pere;
- Shao, Kun;
- Yang, Yang
Publication type:
journal article
Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer.
Published in:
2020
By:
- Beltran, Himisha;
- Romanel, Alessandro;
- Conteduca, Vincenza;
- Casiraghi, Nicola;
- Sigouros, Michael;
- Franceschini, Gian Marco;
- Orlando, Francesco;
- Fedrizzi, Tarcisio;
- Sheng-Yu Ku;
- Dann, Emma;
- Alonso, Alicia;
- Miguel Mosquera, Juan;
- Sboner, Andrea;
- Jenny Xiang;
- Elemento, Olivier;
- Nanus, David M.;
- Tagawa, Scott T.;
- Benelli, Matteo;
- Demichelis, Francesca;
- Ku, Sheng-Yu
Publication type:
journal article
Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS.
Published in:
Journal of Clinical Investigation, 2020, v. 130, n. 4, p. 1977, doi. 10.1172/jci130308
By:
- Zhilin Li;
- Korhonen, Emilia A.;
- Merlini, Arianna;
- Strauss, Judith;
- Wihuri, Eleonoora;
- Nurmi, Harri;
- Antila, Salli;
- Paech, Jennifer;
- Deutsch, Urban;
- Engelhardt, Britta;
- Chintharlapalli, Sudhakar;
- Gou Young Koh;
- Flügel, Alexander;
- Alitalo, Kari
Publication type:
Article
Personal tumor antigens in blood malignancies: genomics-directed identification and targeting.
Published in:
2020
By:
- Penter, Livius;
- Wu, Catherine J.
Publication type:
journal article
The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas.
Published in:
2020
By:
- Valencia, Karmele;
- Erice, Oihane;
- Kostyrko, Kaja;
- Hausmann, Simone;
- Guruceaga, Elizabeth;
- Tathireddy, Anuradha;
- Flores, Natasha M.;
- Sayles, Leanne C.;
- Lee, Alex G.;
- Fragoso, Rita;
- Tian-Qiang Sun;
- Vallejo, Adrian;
- Roman, Marta;
- Entrialgo-Cadierno, Rodrigo;
- Migueliz, Itziar;
- Razquin, Nerea;
- Fortes, Puri;
- Lecanda, Fernando;
- Jun Lu;
- Ponz-Sarvise, Mariano
Publication type:
journal article
Plasminogen as a prognostic biomarker for HBV-related acute-on-chronic liver failure.
Published in:
2020
By:
- Daxian Wu;
- Sainan Zhang;
- Zhongyang Xie;
- Ermei Chen;
- Qunfang Rao;
- Xiaoli Liu;
- Kaizhou Huang;
- Jing Yang;
- Lanlan Xiao;
- Feiyang Ji;
- Zhengyi Jiang;
- Yalei Zhao;
- Xiaoxi Ouyang;
- Danhua Zhu;
- Xiahong Dai;
- Zhouhua Hou;
- Bingjie Liu;
- Binbin Deng;
- Ning Zhou;
- Hainv Gao
Publication type:
journal article
Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation.
Published in:
2020
By:
- Ortiz-Muñoz, Guadalupe;
- Yu, Michelle A.;
- Lefrançais, Emma;
- Mallavia, Beñat;
- Valet, Colin;
- Tian, Jennifer J.;
- Ranucci, Serena;
- Wang, Kristin M.;
- Zhe Liu;
- Kwaan, Nicholas;
- Dawson, Diana;
- Kleinhenz, Mary Ellen;
- Khasawneh, Fadi T.;
- Haggie, Peter M.;
- Verkman, Alan S.;
- Looney, Mark R.;
- Liu, Zhe
Publication type:
journal article
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.
Published in:
2020
By:
- Xiaobo Luo;
- Donnelly, Christopher R.;
- Wang Gong;
- Heath, Blake R.;
- Yuning Hao;
- Donnelly, Lorenza A.;
- Moghbeli, Toktam;
- Yee Sun Tan;
- Xin Lin;
- Bellile, Emily;
- Kansy, Benjamin A.;
- Carey, Thomas E.;
- Brenner, J. Chad;
- Lei Cheng;
- Polverini, Peter J.;
- Morgan, Meredith A.;
- Haitao Wen;
- Prince, Mark E.;
- Ferris, Robert L.;
- Yuying Xie
Publication type:
journal article
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases.
Published in:
2020
By:
- de Jesus, Adriana A.;
- Yangfeng Hou;
- Brooks, Stephen;
- Malle, Louise;
- Biancotto, Angelique;
- Yan Huang;
- Calvo, Katherine R.;
- Marrero, Bernadette;
- Moir, Susan;
- Oler, Andrew J.;
- Zuoming Deng;
- Sanchez, Gina A. Montealegre;
- Ahmed, Amina;
- Allenspach, Eric;
- Arabshahi, Bita;
- Behrens, Edward;
- Benseler, Susanne;
- Bezrodnik, Liliana;
- Bout-Tabaku, Sharon;
- Brescia, AnneMarie C.
Publication type:
journal article
Immunotherapy of lymphomas.
Published in:
2020
By:
- Ansell, Stephen M.;
- Yi Lin;
- Lin, Yi
Publication type:
journal article
Immune escape and immunotherapy of acute myeloid leukemia.
Published in:
2020
By:
- Vago, Luca;
- Gojo, Ivana
Publication type:
journal article
Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β-mediated colitis.
Published in:
2020
By:
- Mao, Liming;
- Kitani, Atsushi;
- Hiejima, Eitaro;
- Montgomery-Recht, Kim;
- Wenchang Zhou;
- Fuss, Ivan;
- Wiestner, Adrian;
- Strober, \Warren;
- Zhou, Wenchang
Publication type:
journal article
Immunotherapy of multiple myeloma.
Published in:
2020
By:
- Minnie, Simone A.;
- Hill, Geoffrey R.
Publication type:
journal article
Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy.
Published in:
2020
By:
- Himelman, Eric;
- Lillo, Mauricio A.;
- Nouet, Julie;
- Gonzalez, J. Patrick;
- Qingshi Zhao;
- Lai-Hua Xie;
- Hong Li;
- Tong Liu;
- Wehrens, Xander H. T.;
- Lampe, Paul D.;
- Fishman, Glenn I.;
- Shirokova, Natalia;
- Contreras, Jorge E.;
- Fraidenraich, Diego;
- Zhao, Qingshi;
- Xie, Lai-Hua;
- Li, Hong;
- Liu, Tong;
- Wehrens, Xander Ht
Publication type:
journal article
Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration.
Published in:
2020
By:
- Pinto-Costa, Rita;
- Sousa, Sara C.;
- Leite, Sérgio C.;
- Nogueira-Rodrigues, Joana;
- Ferreira da Silva, Tiago;
- Machado, Diana;
- Marques, Joana;
- Costa, Ana Catarina;
- Liz, Márcia A.;
- Bartolini, Francesca;
- Brites, Pedro;
- Costell, Mercedes;
- Fässler, Reinhard;
- Sousa, Mónica M.
Publication type:
journal article
Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1.
Published in:
2020
By:
- Leiming Wang;
- Mafei Xu;
- Kao, Chung-Yang;
- Tsai, Sophia Y.;
- Tsai, Ming-Jer;
- Wang, Leiming;
- Xu, Mafei
Publication type:
journal article
Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma.
Published in:
2020
By:
- Kewen Hu;
- Kun Li;
- Jing Lv;
- Jie Feng;
- Jing Chen;
- Haigang Wu;
- Feixiong Cheng;
- Wenhao Jiang;
- Jieqiong Wang;
- Haixiang Pei;
- Chiao, Paul J.;
- Zhenyu Cai;
- Yihua Chen;
- Mingyao Liu;
- Xiufeng Pang;
- Hu, Kewen;
- Li, Kun;
- Lv, Jing;
- Feng, Jie;
- Chen, Jing
Publication type:
journal article
Visceral adipose NLRP3 impairs cognition in obesity via IL-1R1 on CX3CR1+ cells.
Published in:
2020
By:
- Guo, De-Huang;
- Yamamoto, Masaki;
- Hernandez, Caterina M.;
- Khodadadi, Hesam;
- Baban, Babak;
- Stranahan, Alexis M.
Publication type:
journal article
Targeting AML-associated FLT3 mutations with a type I kinase inhibitor.
Published in:
2020
By:
- Jones, LaQuita M.;
- Melgar, Katelyn;
- Bolanos, Lyndsey;
- Hueneman, Kathleen;
- Walker, Morgan M.;
- Jian-Kang Jiang;
- Wilson, Kelli M.;
- Xiaohu Zhang;
- Jian Shen;
- Fan Jiang;
- Sutter, Patrick;
- Wang, Amy;
- Xin Xu;
- Tawa, Gregory J.;
- Hoyt, Scott B.;
- Wunderlich, Mark;
- O’Brien, Eric;
- Perentesis, John P.;
- Starczynowski, Daniel T.;
- Thomas, Craig J.
Publication type:
journal article

Found: 52