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Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.
Published in:
2019
By:
- Nambiar, Dhanya K.;
- Aguilera, Todd;
- Hongbin Cao;
- Kwok, Shirley;
- Kong, Christina;
- Bloomstein, Joshua;
- Zemin Wang;
- Rangan, Vangipuram S.;
- Dadi Jiang;
- von Eyben, Rie;
- Liang, Rachel;
- Agarwal, Sonya;
- Colevas, A. Dimitrios;
- Korman, Alan;
- Allen, Clint T.;
- Uppaluri, Ravindra;
- Koong, Albert C.;
- Giaccia, Amato;
- Quynh Thu Le;
- Cao, Hongbin
Publication type:
journal article
Paroxysmal nocturnal hemoglobinuria without GPI-anchor deficiency.
Published in:
2019
By:
- Brodsky, Robert A.
Publication type:
journal article
High-fat diet exacerbates SIV pathogenesis and accelerates disease progression.
Published in:
2019
By:
- Tianyu He;
- Cuiling Xu;
- Krampe, Noah;
- Dillon, Stephanie M.;
- Sette, Paola;
- Falwell, Elizabeth;
- Haret-Richter, George S.;
- Butterfield, Tiffany;
- Dunsmore, Tammy L.;
- McFadden Jr., William M.;
- Martin, Kathryn J.;
- Policicchio, Benjamin B.;
- Raehtz, Kevin D.;
- Penn, Ellen P.;
- Tracy, Russell P.;
- Ribeiro, Ruy M.;
- Frank, Daniel N.;
- Wilson, Cara C.;
- Landay, Alan L.;
- Apetrei, Cristian
Publication type:
journal article
Hyperuricemia and gout caused by missense mutation in d-lactate dehydrogenase.
Published in:
2019
By:
- Drabkin, Max;
- Yogev, Yuval;
- Zeller, Lior;
- Zarivach, Raz;
- Zalk, Ran;
- Halperin, Daniel;
- Wormser, Ohad;
- Gurevich, Evgenia;
- Landau, Daniel;
- Kadir, Rotem;
- Perez, Yonatan;
- Birk, Ohad S.
Publication type:
journal article
The ownership paradox: nurturing continuity and change for the future ASCI.
Published in:
2019
By:
- Marr, Kieren A.
Publication type:
journal article
Challenges in optimizing preexposure prophylaxis development, engagement, and access for HIV prevention.
Published in:
2019
By:
- Scully, Eileen P.;
- Weld, Ethel D.;
- Blankson, Joel N.
Publication type:
journal article
Cancer immunotherapy needs to learn how to stick to its guns.
Published in:
2019
By:
- Chakraborty, Asmi;
- Dimitroff, Charles J.
Publication type:
journal article
C. Ronald Kahn: The Louisville Slugger of metabolic science.
Published in:
2019
By:
- Flier, Jeffrey S.
Publication type:
journal article
Manganese homeostasis: from rare single-gene disorders to complex phenotypes and diseases.
Published in:
2019
By:
- Katz, Nathan;
- Rader, Daniel J.
Publication type:
journal article
Destress and do not suppress: targeting adrenergic signaling in tumor immunosuppression.
Published in:
2019
By:
- Iñigo-Marco, Ignacio;
- Alonso, Marta M.
Publication type:
journal article
Adding chimeric antigen receptor-induced killer cells to the medical oncology shelf.
Published in:
2019
By:
- Brandjes, Brigett D.;
- Davila, Marco L.
Publication type:
journal article
Beclin-1 as a neutrophil-specific immune checkpoint.
Published in:
2019
By:
- Yu-Lin Su;
- Kortylewski, Marcin;
- Su, Yu-Lin
Publication type:
journal article
Waiting to "make it" versus "making it happen": empowering physician-scientists in training.
Published in:
2019
By:
- Iness, Audra N.
Publication type:
journal article
Diversification in the medical sciences fuels growth of physician-scientists.
Published in:
2019
By:
- Carethers, John M.
Publication type:
journal article
A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis.
Published in:
2019
By:
- Xiaoyan Xu;
- Yumeng Wang;
- Mojumdar, Kamalika;
- Zhicheng Zhou;
- Kang Jin Jeong;
- Mangala, Lingegowda S.;
- Shuangxing Yu;
- Yiu Huen Tsang;
- Rodriguez-Aguayo, Cristian;
- Yiling Lu;
- Lopez-Berestein, Gabriel;
- Sood, Anil K.;
- Mills, Gordon B.;
- Han Liang;
- Xu, Xiaoyan;
- Wang, Yumeng;
- Zhou, Zhicheng;
- Jeong, Kang Jin;
- Yu, Shuangxing;
- Tsang, Yiu Huen
Publication type:
journal article
Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.
Published in:
2019
By:
- Hugelshofer, Michael;
- Buzzi, Raphael M.;
- Schaer, Christian A.;
- Richter, Henning;
- Akeret, Kevin;
- Anagnostakou, Vania;
- Mahmoudi, Leila;
- Vaccani, Raphael;
- Vallelian, Florence;
- Deuel, Jeremy W.;
- Kronen, Peter W.;
- Kulcsar, Zsolt;
- Regli, Luca;
- Jin Hyen Baek;
- Pires, Ivan S.;
- Palmer, Andre F.;
- Dennler, Matthias;
- Humar, Rok;
- Buehler, Paul W.;
- Kircher, Patrick R.
Publication type:
journal article
Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models.
Published in:
2019
By:
- Morelli, Kathryn H.;
- Griffin, Laurie B.;
- Pyne, Nettie K.;
- Wallace, Lindsay M.;
- Fowler, Allison M.;
- Oprescu, Stephanie N.;
- Ryuichi Takase;
- Na Wei;
- Meyer-Schuman, Rebecca;
- Mellacheruvu, Dattatreya;
- Kitzman, Jacob O.;
- Kocen, Samuel G.;
- Hines, Timothy J.;
- Spaulding, Emily L.;
- Lupski, James R.;
- Nesvizhskii, Alexey;
- Mancias, Pedro;
- Butler, Ian J.;
- Xiang-Lei Yang;
- Ya-Ming Hou
Publication type:
journal article
SHP2 inhibition reduces leukemogenesis in models of combined genetic and epigenetic mutations.
Published in:
2019
By:
- Pandey, Ruchi;
- Ramdas, Baskar;
- Changlin Wan;
- Sandusky, George;
- Mohseni, Morvarid;
- Chi Zhang;
- Kapur, Reuben;
- Wan, Changlin;
- Zhang, Chi
Publication type:
journal article
Cannabidiol attenuates seizures and EEG abnormalities in Angelman syndrome model mice.
Published in:
2019
By:
- Bin Gu;
- Manhua Zhu;
- Glass, Madison R.;
- Rougié, Marie;
- Nikolova, Viktoriya D.;
- Moy, Sheryl S.;
- Carney, Paul R.;
- Philpot, Benjamin D.;
- Gu, Bin;
- Zhu, Manhua
Publication type:
journal article
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice.
Published in:
2019
By:
- Zhuzhen Zhang;
- Mengle Shao;
- Hepler, Chelsea;
- Zhenzhen Zi;
- Shangang Zhao;
- Yu A. An;
- Yi Zhu;
- Ghaben, Alexandra L.;
- May-yun Wang;
- Na Li;
- Toshiharu Onodera;
- Joffin, Nolwenn;
- Crewe, Clair;
- Qingzhang Zhu;
- Vishvanath, Lavanya;
- Kumar, Ashwani;
- Chao Xing;
- Qiong A. Wang;
- Gautron, Laurent;
- Yingfeng Deng
Publication type:
journal article
Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling.
Published in:
2019
By:
- Shigeki Nishimori;
- O'Meara, Maureen J.;
- Castro, Christian D.;
- Hiroshi Noda;
- Cetinbas, Murat;
- da Silva Martins, Janaina;
- Ayturk, Ugur;
- Brooks, Daniel J.;
- Bruce, Michael;
- Mizuki Nagata;
- Ono, Wanida;
- Janton, Christopher J.;
- Bouxsein, Mary L.;
- Foretz, Marc;
- Berdeaux, Rebecca;
- Sadreyev, Ruslan I.;
- Gardella, Thomas J.;
- Jüppner, Harald;
- Kronenberg, Henry M.;
- Wein, Marc N.
Publication type:
journal article
Sonic Hedgehog repression underlies gigaxonin mutation-induced motor deficits in giant axonal neuropathy.
Published in:
2019
By:
- Arribat, Yoan;
- Mysiak, Karolina S.;
- Lescouzères, Léa;
- Boizot, Alexia;
- Ruiz, Maxime;
- Rossel, Mireille;
- Bomont, Pascale
Publication type:
journal article
P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation.
Published in:
2019
By:
- Nagai, Jun;
- Balestrieri, Barbara;
- Fanning, Laura B.;
- Kyin, Timothy;
- Cirka, Haley;
- Junrui Lin;
- Idzko, Marco;
- Zech, Andreas;
- Kim, Edy Y.;
- Brennan, Patrick J.;
- Boyce, Joshua A.;
- Lin, Junrui
Publication type:
journal article
Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity.
Published in:
2019
By:
- Mercadante, Courtney J.;
- Prajapati, Milankumar;
- Conboy, Heather L.;
- Dash, Miriam E.;
- Herrera, Carolina;
- Pettiglio, Michael A.;
- Cintron-Rivera, Layra;
- Salesky, Madeleine A.;
- Rao, Deepa B.;
- Bartnikas, Thomas B.
Publication type:
journal article
β2 adrenergic receptor-mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells.
Published in:
2019
By:
- Mohammadpour, Hemn;
- MacDonald, Cameron R.;
- Guanxi Qiao;
- Minhui Chen;
- Dong, Bowen;
- Hylander, Bonnie L.;
- McCarthy, Philip L.;
- Abrams, Scott I.;
- Repasky, Elizabeth A.;
- Qiao, Guanxi;
- Chen, Minhui
Publication type:
journal article
Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions.
Published in:
2019
By:
- Nan Chiang;
- Libreros, Stephania;
- Norris, Paul C.;
- de la Rosa, Xavier;
- Serhan, Charles N.;
- Chiang, Nan
Publication type:
journal article
Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.
Published in:
2019
By:
- Randzavola, Lyra O.;
- Strege, Katharina;
- Juzans, Marie;
- Yukako Asano;
- Stinchcombe, Jane C.;
- Gawden-Bone, Christian M.;
- Seaman, Matthew N. J.;
- Kuijpers, Taco W.;
- Griffiths, Gillian M.;
- Asano, Yukako;
- Seaman, Matthew Nj
Publication type:
journal article
Hedgehog signaling promotes tumor-associated macrophage polarization to suppress intratumoral CD8+ T cell recruitment.
Published in:
2019
By:
- Petty, Amy J.;
- Ang Li;
- Xinyi Wang;
- Rui Dai;
- Heyman, Benjamin;
- Hsu, David;
- Xiaopei Huang;
- Yiping Yang;
- Li, Ang;
- Wang, Xinyi;
- Dai, Rui;
- Huang, Xiaopei;
- Yang, Yiping
Publication type:
journal article
Loss-of-function variants in myocardin cause congenital megabladder in humans and mice.
Published in:
2019
By:
- Houweling, Arjan C.;
- Beaman, Glenda M.;
- Postma, Alex V.;
- Gainous, T. Blair;
- Lichtenbelt, Klaske D.;
- Brancati, Francesco;
- Lopes, Filipa M.;
- van der Made, Ingeborg;
- Polstra, Abeltje M.;
- Robinson, Michael L.;
- Wright, Kevin D.;
- Ellingford, Jamie M.;
- Jackson, Ashley R.;
- Overwater, Eline;
- Genesio, Rita;
- Romano, Silvio;
- Camerota, Letizia;
- D'Angelo, Emanuela;
- Meijers-Heijboer, Elizabeth J.;
- Christoffels, Vincent M.
Publication type:
journal article
Fracture repair requires TrkA signaling by skeletal sensory nerves.
Published in:
2019
By:
- Zhu Li;
- Meyers, Carolyn A.;
- Chang, Leslie;
- Seungyong Lee;
- Zhi Li;
- Tomlinson, Ryan;
- Hoke, Ahmet;
- Clemens, Thomas L.;
- James, Aaron W.;
- Li, Zhu;
- Lee, Seungyong;
- Li, Zhi
Publication type:
journal article
Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury.
Published in:
2019
By:
- Win, Sanda;
- Min, Robert W. M.;
- Chen, Christopher Q.;
- Jun Zhang;
- Yibu Chen;
- Meng Li;
- Ayako Suzuki;
- Abdelmalek, Manal F.;
- Ying Wang;
- Aghajan, Mariam;
- Aung, Filbert W. M.;
- Diehl, Anna Mae;
- Davis, Roger J.;
- Than, Tin A.;
- Kaplowitz, Neil;
- Min, Robert Wm;
- Zhang, Jun;
- Chen, Yibu;
- Li, Meng;
- Suzuki, Ayako
Publication type:
journal article
mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation.
Published in:
2019
By:
- Asrani, Kaushal;
- Murali, Sanjana;
- Lam, Brandon;
- Chan-Hyun Na;
- Phatak, Pornima;
- Sood, Akshay;
- Kaur, Harsimar;
- Khan, Zoya;
- Noë, Michaël;
- Anchoori, Ravi K.;
- Talbot Jr., C. Conover;
- Smith, Barbara;
- Skaro, Michael;
- Lotan, Tamara L.;
- Na, Chan-Hyun;
- Talbot, C Conover Jr
Publication type:
journal article
Schwann cells expressing nociceptive channel TRPA1 orchestrate ethanol-evoked neuropathic pain in mice.
Published in:
2019
By:
- De Logu, Francesco;
- Puma, Simone Li;
- Landini, Lorenzo;
- Portelli, Francesca;
- Innocenti, Alessandro;
- Monteiro de Araujo, Daniel Souza;
- Janal, Malvin N.;
- Patacchini, Riccardo;
- Bunnett, Nigel W.;
- Geppetti, Pierangelo;
- Nassini, Romina;
- Li Puma, Simone;
- de Araujo, Daniel Souza Monteiro
Publication type:
journal article
Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity.
Published in:
2019
By:
- Takayuki Katsuyama;
- Hao Li;
- Comte, Denis;
- Tsokos, George C.;
- Moulton, Vaishali R.;
- Katsuyama, Takayuki;
- Li, Hao
Publication type:
journal article
Myeloid loss of Beclin 1 promotes PD-L1hi precursor B cell lymphoma development.
Published in:
2019
By:
- Peng Tan;
- Lian He;
- Changsheng Xing;
- Jingrong Mao;
- Xiao Yu;
- Motao Zhu;
- Lixia Diao;
- Leng Han;
- Yubin Zhou;
- You, James M.;
- Wang, Helen Y.;
- Rong-Fu Wang;
- Tan, Peng;
- He, Lian;
- Xing, Changsheng;
- Mao, Jingrong;
- Yu, Xiao;
- Zhu, Motao;
- Diao, Lixia;
- Han, Leng
Publication type:
journal article
Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response.
Published in:
2019
By:
- Sahraei, Mahnaz;
- Chaube, Balkrishna;
- Yuting Liu;
- Sun, Jonathan;
- Kaplan, Alanna;
- Price, Nathan L.;
- Wen Ding;
- Oyaghire, Stanley;
- García-Milian, Rolando;
- Mehta, Sameet;
- Reshetnyak, Yana K.;
- Bahal, Raman;
- Fiorina, Paolo;
- Glazer, Peter M.;
- Rimm, David L.;
- Fernández-Hernando, Carlos;
- Suárez, Yajaira;
- Liu, Yuting;
- Ding, Wen
Publication type:
journal article
Chimeric antigen receptor-induced BCL11B suppression propagates NK-like cell development.
Published in:
2019
By:
- Maluski, Marcel;
- Ghosh, Arnab;
- Herbst, Jessica;
- Scholl, Vanessa;
- Baumann, Rolf;
- Huehn, Jochen;
- Geffers, Robert;
- Meyer, Johann;
- Maul, Holger;
- Eiz-Vesper, Britta;
- Krueger, Andreas;
- Schambach, Axel;
- van den Brink, Marcel R. M.;
- Sauer, Martin G.;
- van den Brink, Marcel Rm
Publication type:
journal article
Endogenous T cells prevent tumor immune escape following adoptive T cell therapy.
Published in:
2019
By:
- Walsh, Scott R.;
- Simovic, Boris;
- Lan Chen;
- Bastin, Donald;
- Nguyen, Andrew;
- Stephenson, Kyle;
- Mandur, Talveer S.;
- Bramson, Jonathan L.;
- Lichty, Brian D.;
- Yonghong Wan;
- Chen, Lan;
- Wan, Yonghong
Publication type:
journal article
Mechanisms of reactivation of latent tuberculosis infection due to SIV coinfection.
Published in:
2019
By:
- Bucşan, Allison N.;
- Chatterjee, Ayan;
- Singh, Dhiraj K.;
- Foreman, Taylor W.;
- Tae-Hyung Lee;
- Threeton, Breanna;
- Kirkpatrick, Melanie G.;
- Ahmed, Mushtaq;
- Golden, Nadia;
- Alvarez, Xavier;
- Hoxie, James A.;
- Mehra, Smriti;
- Rengarajan, Jyothi;
- Khader, Shabaana A.;
- Kaushal, Deepak;
- Lee, Tae-Hyung
Publication type:
journal article
FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury.
Published in:
2019
By:
- Chang-Panesso, Monica;
- Kadyrov, Farid F.;
- Lalli, Matthew;
- Haojia Wu;
- Shiyo Ikeda;
- Kefaloyianni, Eirini;
- Abdelmageed, Mai M.;
- Herrlich, Andreas;
- Akio Kobayashi;
- Humphreys, Benjamin D.;
- Wu, Haojia;
- Ikeda, Shiyo;
- Kobayashi, Akio
Publication type:
journal article
CCL28-induced RARβ expression inhibits oral squamous cell carcinoma bone invasion.
Published in:
2019
By:
- Junhee Park;
- Xianglan Zhang;
- Sun Kyoung Lee;
- Na-Young Song;
- Seung Hwa Son;
- Ki Rim Kim;
- Jae Hoon Shim;
- Kwang-Kyun Park;
- Won-Yoon Chung;
- Park, Junhee;
- Zhang, Xianglan;
- Lee, Sun Kyoung;
- Song, Na-Young;
- Son, Seung Hwa;
- Kim, Ki Rim;
- Shim, Jae Hoon;
- Park, Kwang-Kyun;
- Chung, Won-Yoon
Publication type:
journal article
HLA-B27-mediated activation of TNAP phosphatase promotes pathogenic syndesmophyte formation in ankylosing spondylitis.
Published in:
2019
By:
- Chin-Hsiu Liu;
- Sengupta Raj;
- Chun-Hsiung Chen;
- Kuo-Hsuan Hung;
- Chung-Tei Chou;
- Ing-Ho Chen;
- Jui-Teng Chien;
- I-Ying Lin;
- Shii-Yi Yang;
- Takashi Angata;
- Wen-Chan Tsai;
- Cheng-Chung Wei, James;
- I-Shiang Tzeng;
- Shih-Chieh Hung;
- Kuo-I Lin;
- Liu, Chin-Hsiu;
- Raj, Sengupta;
- Chen, Chun-Hsiung;
- Hung, Kuo-Hsuan;
- Chou, Chung-Tei
Publication type:
journal article
Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis.
Published in:
2019
By:
- Welsh, John D.;
- Hoofnagle, Mark H.;
- Bamezai, Sharika;
- Oxendine, Michael;
- Lim, Lillian;
- Hall, Joshua D.;
- Jisheng Yang;
- Schultz, Susan;
- Engel, James Douglas;
- Tsutomu Kume;
- Oliver, Guillermo;
- Jimenez, Juan M.;
- Kahn, Mark L.;
- Yang, Jisheng;
- Kume, Tsutomu
Publication type:
journal article
Slowing ribosome velocity restores folding and function of mutant CFTR.
Published in:
2019
By:
- Oliver, Kathryn E.;
- Rauscher, Robert;
- Mijnders, Marjolein;
- Wei Wang;
- Wolpert, Matthew J.;
- Maya, Jessica;
- Sabusap, Carleen M.;
- Kesterson, Robert A.;
- Kirk, Kevin L.;
- Rab, Andras;
- Braakman, Ineke;
- Jeong S. Hong;
- Hartman IV, John L.;
- Ignatova, Zoya;
- Sorscher, Eric J.;
- Wang, Wei;
- Hong, Jeong S;
- Hartman, John L 4th
Publication type:
journal article
Soluble epoxide hydrolase promotes astrocyte survival in retinopathy of prematurity.
Published in:
2019
By:
- Jiong Hu;
- Bibli, Sofia-Iris;
- Wittig, Janina;
- Zukunft, Sven;
- Jihong Lin;
- Hammes, Hans-Peter;
- Popp, Rüdiger;
- Fleming, Ingrid;
- Hu, Jiong;
- Lin, Jihong
Publication type:
journal article
Complement and inflammasome overactivation mediates paroxysmal nocturnal hemoglobinuria with autoinflammation.
Published in:
2019
By:
- Höchsmann, Britta;
- Yoshiko Murakami;
- Makiko Osato;
- Knaus, Alexej;
- Michi Kawamoto;
- Norimitsu Inoue;
- Tetsuya Hirata;
- Shogo Murata;
- Anliker, Markus;
- Eggermann, Thomas;
- Jäger, Marten;
- Floettmann, Ricarda;
- Höllein, Alexander;
- Sho Murase;
- Yasutaka Ueda;
- Jun-ichi Nishimura;
- Yuzuru Kanakura;
- Nobuo Kohara;
- Schrezenmeier, Hubert;
- Krawitz, Peter M.
Publication type:
journal article
Caspase-8 modulates physiological and pathological angiogenesis during retina development.
Published in:
2019
By:
- Tisch, Nathalie;
- Freire-Valls, Aida;
- Yerbes, Rosario;
- Paredes, Isidora;
- La Porta, Silvia;
- Xiaohong Wang;
- Martín-Pérez, Rosa;
- Castro, Laura;
- Wong, Wendy Wei-Lynn;
- Coultas, Leigh;
- Strilic, Boris;
- Gröne, Hermann-Josef;
- Hielscher, Thomas;
- Mogler, Carolin;
- Adams, Ralf H.;
- Heiduschka, Peter;
- Claesson-Welsh, Lena;
- Mazzone, Massimiliano;
- López-Rivas, Abelardo;
- Schmidt, Thomas
Publication type:
journal article

Found: 47