OpenURL Connection Search

Select item for more details and to access through your institution.

ASCPT News.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1378, doi. 10.1002/cpt.2267
Publication type:
Article
Effect of Corticosteroids on Mortality in Hospitalized COVID‐19 Patients Not Receiving Invasive Mechanical Ventilation.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1660, doi. 10.1002/cpt.2245
By:
- Fusina, Federica;
- Albani, Filippo;
- Granato, Enza;
- Meloni, Angelo;
- Rozzini, Renzo;
- Sabatini, Tony;
- Stellini, Roberto;
- Terragnoli, Paolo;
- Rosano, Antonio;
- Abu Hilal, Mohammed;
- Natalini, Giuseppe
Publication type:
Article
The Uncertainties of Metamizole Use.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1373, doi. 10.1002/cpt.2258
By:
- Cascorbi, Ingolf
Publication type:
Article
Impact of Acute Inflammation on Cytochromes P450 Activity Assessed by the Geneva Cocktail.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1668, doi. 10.1002/cpt.2146
By:
- Lenoir, Camille;
- Daali, Youssef;
- Rollason, Victoria;
- Curtin, François;
- Gloor, Yvonne;
- Bosilkovska, Marija;
- Walder, Bernhard;
- Gabay, Cem;
- Nissen, Michael John;
- Desmeules, Jules Alexandre;
- Hannouche, Didier;
- Samer, Caroline Flora
Publication type:
Article
Highlights.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1376, doi. 10.1002/cpt.2250
Publication type:
Article
CORRIGENDUM: DNL104, a Centrally Penetrant RIPK1 Inhibitor, Inhibits RIP1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1678, doi. 10.1002/cpt.2242
Publication type:
Article
COVID‐19 and the Emerging Regulatory Guidance for Ongoing Clinical Trials in the European Union.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1517, doi. 10.1002/cpt.2225
By:
- Jong, Amos Jochanan;
- Santa‐Ana‐Tellez, Yared;
- Thiel, Ghislaine José Madeleine Wilhelmien;
- Zuidgeest, Mira Gerta Petra;
- Siiskonen, Satu Johanna;
- Mistry, Dinesh;
- Boer, Anthonius;
- Gardarsdottir, Helga
Publication type:
Article
In This Issue.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1371, doi. 10.1002/cpt.2257
Publication type:
Article
Corrigendum: Drug‐Related Hospitalization at a Tertiary Teaching Center in Lebanon: Incidence, Associations, and Relation to Self‐Medicating Behavior.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1677, doi. 10.1002/cpt.2211
Publication type:
Article
A Multipurpose First‐in‐Human Study With the Novel CXCR7 Antagonist ACT‐1004‐1239 Using CXCL12 Plasma Concentrations as Target Engagement Biomarker.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1648, doi. 10.1002/cpt.2154
By:
- Huynh, Christine;
- Henrich, Andrea;
- Strasser, Daniel S.;
- Boof, Marie‐Laure;
- Al‐Ibrahim, Mohamed;
- Meyer Zu Schwabedissen, Henriette E.;
- Dingemanse, Jasper;
- Ufer, Mike
Publication type:
Article
Tribute: Sir Colin Terence Dollery, MB, Ch, MD (Hon).
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1388, doi. 10.1002/cpt.2150
By:
- Atkinson, Arthur J.
Publication type:
Article
Real‐World Infliximab Pharmacokinetic Study Informs an Electronic Health Record‐Embedded Dashboard to Guide Precision Dosing in Children with Crohn's Disease.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1639, doi. 10.1002/cpt.2148
By:
- Xiong, Ye;
- Mizuno, Tomoyuki;
- Colman, Ruben;
- Hyams, Jeffrey;
- Noe, Joshua D.;
- Boyle, Brendan;
- Tsai, Yi‐Ting;
- Dong, Min;
- Jackson, Kimberly;
- Punt, Nieko;
- Rosen, Michael J.;
- Denson, Lee A.;
- Vinks, Alexander A.;
- Minar, Phillip
Publication type:
Article
Reapproaching Old Treatments: Considerations for PK/PD Studies on Phage Therapy for Bacterial Respiratory Infections.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1443, doi. 10.1002/cpt.2214
By:
- Schmalstig, Alan A.;
- Freidy, Soha;
- Hanafin, Patrick O.;
- Braunstein, Miriam;
- Rao, Gauri G.
Publication type:
Article
Individual Atrasentan Exposure is Associated With Long‐term Kidney and Heart Failure Outcomes in Patients With Type 2 Diabetes and Chronic Kidney Disease.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1631, doi. 10.1002/cpt.2143
By:
- Koomen, Jeroen V.;
- Stevens, Jasper;
- Bakris, George;
- Correa‐Rotter, Ricardo;
- Hou, Fan Fan;
- Kitzman, Dalane W.;
- Kohan, Donald E.;
- Makino, Hirofumi;
- McMurray, John J. V.;
- Parving, Hans‐Henrik;
- Perkovic, Vlado;
- Tobe, Sheldon W.;
- Zeeuw, Dick;
- Heerspink, Hiddo J. L.
Publication type:
Article
Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1505, doi. 10.1002/cpt.2141
By:
- Bachmann, Fabio;
- Duthaler, Urs;
- Meyer zu Schwabedissen, Henriette E.;
- Puchkov, Maxim;
- Huwyler, Jörg;
- Haschke, Manuel;
- Krähenbühl, Stephan
Publication type:
Article
Impact of Hepatic CYP3A4 Ontogeny Functions on Drug–Drug Interaction Risk in Pediatric Physiologically‐Based Pharmacokinetic/Pharmacodynamic Modeling: Critical Literature Review and Ivabradine Case Study.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1618, doi. 10.1002/cpt.2134
By:
- Lang, Jennifer;
- Vincent, Ludwig;
- Chenel, Marylore;
- Ogungbenro, Kayode;
- Galetin, Aleksandra
Publication type:
Article
Utility of Normalized TdP Score System in Drug Proarrhythmic Potential Assessment: A Blinded in vitro Study of CiPA Drugs.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1606, doi. 10.1002/cpt.2133
By:
- Liu, Tengxian;
- Liu, Jiang;
- Lu, Hua Rong;
- Li, Haiyan;
- Gallacher, David J.;
- Chaudhary, Khuram;
- Wang, Yaning;
- Yan, Gan‐Xin
Publication type:
Article
Thromboembolic and Hemorrhagic Outcomes in the Direct Oral Anticoagulant Trials Across the Spectrum of Kidney Function.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1593, doi. 10.1002/cpt.2131
By:
- Limdi, Nita A.;
- Beasley, Timothy Mark;
- Sun, Jielin;
- Stockbridge, Norman;
- Pacanowski, Michael;
- Florian, Jeffry
Publication type:
Article
Characterizing Effects of Antidiabetic Drugs on Heart Rate, Systolic and Diastolic Blood Pressure.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1583, doi. 10.1002/cpt.2130
By:
- Maringwa, John;
- Sardu, Maria Luisa;
- Hang, Yaming;
- Czerniak, Richard;
- Vishnubhotla, Manasa;
- Vakilynejad, Majid;
- Pfister, Marc
Publication type:
Article
Experimental Medicine Study to Measure Immune Checkpoint Receptors PD‐1 and GITR Turnover Rates In Vivo in Humans.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1575, doi. 10.1002/cpt.2129
By:
- Lassman, Michael E.;
- Chappell, Derek L.;
- McAvoy, Thomas;
- Cheng, Amy;
- Alwis, Dinesh P.;
- Pruitt, Scott K.;
- Laterza, Omar F.;
- Li, Claire;
- Stoch, Aubrey;
- Mayawala, Kapil
Publication type:
Article
Developing and Validating a Clinical Warfarin Dose‐Initiation Model for Black‐African Patients in South Africa and Uganda.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1564, doi. 10.1002/cpt.2128
By:
- Asiimwe, Innocent G.;
- Waitt, Catriona;
- Sekaggya‐Wiltshire, Christine;
- Hutchinson, Claire;
- Okello, Emmy;
- Zhang, Eunice J.;
- Semakula, Jerome R.;
- Mouton, Johannes P.;
- Cohen, Karen;
- Blockman, Marc;
- Lamorde, Mohammed;
- Jorgensen, Andrea L.;
- Pirmohamed, Munir
Publication type:
Article
Pharmacogenetics at Scale: An Analysis of the UK Biobank.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1528, doi. 10.1002/cpt.2122
By:
- McInnes, Gregory;
- Lavertu, Adam;
- Sangkuhl, Katrin;
- Klein, Teri E.;
- Whirl‐Carrillo, Michelle;
- Altman, Russ B.
Publication type:
Article
Détente: A Practical Understanding of P values and Bayesian Posterior Probabilities.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1489, doi. 10.1002/cpt.2004
By:
- Ruberg, Stephen J.
Publication type:
Article
Points to Consider for Implementation of the ICH E17 Guideline: Learning from Past Multiregional Clinical Trials in Japan.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1555, doi. 10.1002/cpt.2121
By:
- Asano, Kunihito;
- Aoi, Yoko;
- Kamada, Shuji;
- Uyama, Yoshiaki;
- Tohkin, Masahiro
Publication type:
Article
Effects of NT5C2 Germline Variants on 6‐Mecaptopurine Metabolism in Children With Acute Lymphoblastic Leukemia.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1538, doi. 10.1002/cpt.2095
By:
- Jiang, Chuang;
- Yang, Wenjian;
- Moriyama, Takaya;
- Liu, Chengcheng;
- Smith, Colton;
- Yang, Wentao;
- Qian, Maoxiang;
- Li, Ziping;
- Tulstrup, Morten;
- Schmiegelow, Kjeld;
- Crews, Kristine R.;
- Zhang, Hui;
- Pui, Ching‐Hon;
- Evans, William;
- Relling, Mary;
- Bhatia, Smita;
- Yang, Jun J.
Publication type:
Article
Circadian Variation in Efficacy of Medications.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1457, doi. 10.1002/cpt.2073
By:
- Walton, James C.;
- Walker, William H.;
- Bumgarner, Jacob R.;
- Meléndez‐Fernández, O. Hecmarie;
- Liu, Jennifer A.;
- Hughes, Heather L.;
- Kaper, Alexis L.;
- Nelson, Randy J.
Publication type:
Article
Transdermal Testosterone Attenuates Drug‐Induced Lengthening of Both Early and Late Ventricular Repolarization in Older Men.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1499, doi. 10.1002/cpt.2072
By:
- Tomaselli Muensterman, Elena;
- Jaynes, Heather A.;
- Sowinski, Kevin M.;
- Overholser, Brian R.;
- Shen, Changyu;
- Kovacs, Richard J.;
- Tisdale, James E.
Publication type:
Article
Keeping the Pharmacology in Pharmacoepidemiology.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1393, doi. 10.1002/cpt.2006
By:
- Staffa, Judy A.
Publication type:
Article
Differential Effects of Clopidogrel With or Without Aspirin on Platelet Reactivity and Coagulation Activation: A Randomized Trial in Healthy Volunteers.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1546, doi. 10.1002/cpt.2106
By:
- Traby, Ludwig;
- Kollars, Marietta;
- Kaider, Alexandra;
- Siller‐Matula, Jolanta Maria;
- Steinbrecher, Oskar;
- Wolzt, Michael;
- Kyrle, Paul Alexander;
- Eichinger, Sabine
Publication type:
Article
Issue Information.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1363, doi. 10.1002/cpt.1900
Publication type:
Article
Farewell to our Wonderful Friend and Colleague, J. Richard (Dick) Crout (1929–2020).
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1384, doi. 10.1002/cpt.2063
By:
- Temple, Robert J.;
- O'Neill, Robert T.;
- Peck, Carl C.
Publication type:
Article
Postmarket Safety Communication for Protection of Public Health: A Comparison of Regulatory Policy in Australia, Canada, the European Union, and the United States.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1424, doi. 10.1002/cpt.2010
By:
- Bhasale, Alice L.;
- Sarpatwari, Ameet;
- De Bruin, Marie L.;
- Lexchin, Joel;
- Lopert, Ruth;
- Bahri, Priya;
- Mintzes, Barbara J.
Publication type:
Article
COVID‐19: A Catalyst to Accelerate Global Regulatory Transformation.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1390, doi. 10.1002/cpt.2046
By:
- Stewart, Jerry;
- Honig, Peter;
- AlJuburi, Lina;
- Autor, Deborah;
- Berger, Susan;
- Brady, Patrick;
- Fitton, Helen;
- Garner, Carlos;
- Garvin, Michael;
- Hukkelhoven, Mathias;
- Kowalski, Robert;
- Milligan, Sandra;
- O'Dowd, Liza;
- Reilly, Edward;
- Roberts, Khyati;
- Robertson, Andrew S.;
- Taisey, Mark;
- Thakkar, Roopal;
- Van Baelen, Karin;
- Wegner, Max
Publication type:
Article
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1417, doi. 10.1002/cpt.2015
By:
- Lima, John J.;
- Thomas, Cameron D.;
- Barbarino, Julia;
- Desta, Zeruesenay;
- Van Driest, Sara L.;
- El Rouby, Nihal;
- Johnson, Julie A.;
- Cavallari, Larisa H.;
- Shakhnovich, Valentina;
- Thacker, David L.;
- Scott, Stuart A.;
- Schwab, Matthias;
- Uppugunduri, Chakradhara Rao S.;
- Formea, Christine M.;
- Franciosi, James P.;
- Sangkuhl, Katrin;
- Gaedigk, Andrea;
- Klein, Teri E.;
- Gammal, Roseann S.;
- Furuta, Takahisa
Publication type:
Article
Strategies and Recommendations for Using a Data‐Driven and Risk‐Based Approach in the Selection of First‐in‐Human Starting Dose: An International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) Assessment.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1395, doi. 10.1002/cpt.2009
By:
- Leach, Michael W.;
- Clarke, David O.;
- Dudal, Sherri;
- Han, Chao;
- Li, Chunze;
- Yang, Zheng;
- Brennan, Frank R.;
- Bailey, Wendy J.;
- Chen, Yingxue;
- Deslandes, Antoine;
- Loberg, Lise I.;
- Mayawala, Kapil;
- Rogge, Mark C.;
- Todd, Marque;
- Chemuturi, Nagendra V.
Publication type:
Article

Found: 35