Found: 331
Select item for more details and to access through your institution.
PROTAC-mediated conditional degradation of the WRN helicase as a potential strategy for selective killing of cancer cells with microsatellite instability.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-71160-5
- By:
- Publication type:
- Article
Werner's syndrome.
- Published in:
- 2012
- By:
- Publication type:
- Case Study
Diabetes mellitus and cancer in Werner syndrome.
- Published in:
- 2014
- By:
- Publication type:
- Letter
Japanese diabetic patients with Werner syndrome exhibit high incidence of cancer.
- Published in:
- 2012
- By:
- Publication type:
- Letter
Unusual Double Primary Neoplasia: Adrenocortical and Ureteral Carcinomas in Werner Syndrome.
- Published in:
- Urologia Internationalis, 2004, v. 72, n. 2, p. 168, doi. 10.1159/000075974
- By:
- Publication type:
- Article
WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells.
- Published in:
- BMC Molecular & Cell Biology, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s12860-020-00315-9
- By:
- Publication type:
- Article
Werner syndrome associated with poorly differentiated thyroid carcinoma and systemic sclerosis-like skin manifestations: A case report.
- Published in:
- Modern Rheumatology Case Reports, 2024, v. 8, n. 1, p. 95, doi. 10.1093/mrcr/rxad039
- By:
- Publication type:
- Article
A rare syndrome mimicking scleroderma: Werner syndrome.
- Published in:
- Modern Rheumatology Case Reports, 2023, v. 7, n. 1, p. 315, doi. 10.1093/mrcr/rxac077
- By:
- Publication type:
- Article
WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations.
- Published in:
- Human Genetics, 2010, v. 128, n. 1, p. 103, doi. 10.1007/s00439-010-0832-5
- By:
- Publication type:
- Article
The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis.
- Published in:
- Human Genetics, 2008, v. 124, n. 4, p. 369, doi. 10.1007/s00439-008-0562-0
- By:
- Publication type:
- Article
Isolation of a paralog of the Doyne honeycomb retinal dystrophy gene from the multiple retinopathy critical region on 11q13.
- Published in:
- Human Genetics, 2000, v. 106, n. 1, p. 66, doi. 10.1007/s004390051011
- By:
- Publication type:
- Article
Stochastic Simulations of Normal Aging and Werner's Syndrome.
- Published in:
- Bulletin of Mathematical Biology, 2014, v. 76, n. 6, p. 1241, doi. 10.1007/s11538-014-9952-8
- By:
- Publication type:
- Article
Review of How Genetic Research on Segmental Progeroid Syndromes Has Documented Genomic Instability as a Hallmark of Aging But Let Us Now Pursue Antigeroid Syndromes!
- Published in:
- 2021
- By:
- Publication type:
- journal article
Liver Aging and Pseudocapillarization in a Werner Syndrome Mouse Model.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69, n. 9, p. 1076, doi. 10.1093/gerona/glt169
- By:
- Publication type:
- Article
Lack of amyloid plaque formation in the central nervous system of a patient with Werner syndrome.
- Published in:
- Neuropathology, 2003, v. 23, n. 1, p. 51, doi. 10.1046/j.1440-1789.2003.00474.x
- By:
- Publication type:
- Article
Structure of the RecQ C-terminal Domain of Human Bloom Syndrome Protein.
- Published in:
- Scientific Reports, 2013, p. 1, doi. 10.1038/srep03294
- By:
- Publication type:
- Article
James German and the Quest to Understand Human RECQ Helicase Deficiencies.
- Published in:
- Cells (2073-4409), 2024, v. 13, n. 13, p. 1077, doi. 10.3390/cells13131077
- By:
- Publication type:
- Article
MUT-7 Provides Molecular Insight into the Werner Syndrome Exonuclease.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 12, p. 3457, doi. 10.3390/cells10123457
- By:
- Publication type:
- Article
'Werner Syndrome foot'—A case series of four Irish Traveller siblings with Werner Syndrome, diabetes mellitus and complex foot disease.
- Published in:
- Diabetic Medicine, 2024, v. 41, n. 9, p. 1, doi. 10.1111/dme.15390
- By:
- Publication type:
- Article
ZRS 406A>G mutation in patients with tibial hypoplasia, Polydactyly and triphalangeal first fingers.
- Published in:
- Journal of Human Genetics, 2014, v. 59, n. 8, p. 467, doi. 10.1038/jhg.2014.50
- By:
- Publication type:
- Article
WRN helicase accelerates the transcription of ribosomal RNA as a component of an RNA polymerase I-associated complex.
- Published in:
- Oncogene, 2002, v. 21, n. 16, p. 2447, doi. 10.1038/sj.onc.1205334
- By:
- Publication type:
- Article
Diverged nuclear localization of Werner helicase in human and mouse cells.
- Published in:
- Oncogene, 2001, v. 20, n. 20, p. 2551, doi. 10.1038/sj.onc.1204344
- By:
- Publication type:
- Article
Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein – Barr virus.
- Published in:
- Oncogene, 1997, v. 15, n. 16, p. 1911, doi. 10.1038/sj.onc.1201377
- By:
- Publication type:
- Article
Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells.
- Published in:
- Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-022-00939-8
- By:
- Publication type:
- Article
Premature Aging Diseases: Cellular and Molecular Changes.
- Published in:
- BioScience, 1983, v. 33, n. 10, p. 634, doi. 10.2307/1309492
- By:
- Publication type:
- Article
Werner syndrome: A case report and review of literature.
- Published in:
- 2011
- By:
- Publication type:
- Case Study
Treating a patient with the Werner syndrome and osteoporosis using recombinant human insulin-like growth factor.
- Published in:
- 1994
- By:
- Publication type:
- journal article
Nailfold scleroderma-like capillary abnormalities in Werner syndrome (adult progeria).
- Published in:
- 2017
- By:
- Publication type:
- Case Study
Neurological Involvement in Werner’s Syndrome: Clinical and Biopsy Study of a Familial Case.
- Published in:
- European Neurology, 2000, v. 44, n. 3, p. 187, doi. 10.1159/000008234
- By:
- Publication type:
- Article
A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN).
- Published in:
- PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0210525
- By:
- Publication type:
- Article
Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein.
- Published in:
- PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0193170
- By:
- Publication type:
- Article
Prevalence of Werner's syndrome in northern Sardinia: a new case.
- Published in:
- Journal of the European Academy of Dermatology & Venereology, 2003, v. 17, n. 2, p. 248, doi. 10.1046/j.1468-3083.2003.00577_17.x
- By:
- Publication type:
- Article
From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing.
- Published in:
- Cellular & Molecular Life Sciences, 2007, v. 64, n. 19/20, p. 2620, doi. 10.1007/s00018-007-7123-x
- By:
- Publication type:
- Article
Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions.
- Published in:
- Cellular & Molecular Life Sciences, 2007, v. 64, n. 2, p. 155, doi. 10.1007/s00018-006-6349-3
- By:
- Publication type:
- Article
Vitamin C restores healthy aging in a mouse model for Werner syndrome.
- Published in:
- FASEB Journal, 2010, v. 24, n. 1, p. 158, doi. 10.1096/fj.09-137133
- By:
- Publication type:
- Article
Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin.
- Published in:
- Annals of the New York Academy of Sciences, 2010, v. 1197, n. 1, p. 40, doi. 10.1111/j.1749-6632.2010.05189.x
- By:
- Publication type:
- Article
Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts.
- Published in:
- Annals of the New York Academy of Sciences, 2010, v. 1197, n. 1, p. 45, doi. 10.1111/j.1749-6632.2010.05195.x
- By:
- Publication type:
- Article
Modeling Werner Syndrome in Drosophila melanogaster.
- Published in:
- Annals of the New York Academy of Sciences, 2007, v. 1119, p. 274, doi. 10.1196/annals.1404.009
- By:
- Publication type:
- Article
Molecular Mechanisms of Skin Aging.
- Published in:
- Annals of the New York Academy of Sciences, 2007, v. 1119, p. 40, doi. 10.1196/annals.1404.027
- By:
- Publication type:
- Article
The Role of Cellular Senescence in Werner Syndrome.
- Published in:
- Annals of the New York Academy of Sciences, 2007, v. 1100, p. 455, doi. 10.1196/annals.1395.051
- By:
- Publication type:
- Article
Prevention of Accelerated Cell Aging in the Werner Syndrome.
- Published in:
- Annals of the New York Academy of Sciences, 2006, v. 1067, n. 1, p. 243, doi. 10.1196/annals.1354.031
- By:
- Publication type:
- Article
Possible Associations between Successful Aging and Polymorphic Markers in the Werner Gene Region.
- Published in:
- Annals of the New York Academy of Sciences, 2006, v. 1067, n. 1, p. 309, doi. 10.1196/annals.1354.041
- By:
- Publication type:
- Article
Werner's syndrome may be lost in the shadow of the scleroderma.
- Published in:
- Rheumatology International, 2013, v. 33, n. 5, p. 1309, doi. 10.1007/s00296-012-2564-4
- By:
- Publication type:
- Article
Werner’s syndrome: a quite rare disease for differential diagnosis of scleroderma.
- Published in:
- 2010
- By:
- Publication type:
- Report
Severe toxicity of chemotherapy against advanced soft tissue sarcoma in Werner's syndrome: Ifosfamide-induced encephalopathy with central diabetes insipidus.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Ageing: Heterochromatin disorganization associated with premature ageing.
- Published in:
- Nature Reviews Genetics, 2015, v. 16, n. 6, p. 318, doi. 10.1038/nrg3958
- By:
- Publication type:
- Article
In Brief.
- Published in:
- 2003
- Publication type:
- Abstract
Cancer genetics: Who's doing the dirty work for MYC?
- Published in:
- Nature Reviews Genetics, 2003, v. 4, n. 8, p. 581, doi. 10.1038/nrg1147
- By:
- Publication type:
- Article
Significant elevation of IgG anti-WRN (RecQ3 RNA/DNA helicase) antibody in systemic sclerosis.
- Published in:
- Modern Rheumatology, 2006, v. 16, n. 4, p. 229, doi. 10.3109/s10165-006-0496-0
- By:
- Publication type:
- Article
Replication protein A promotes 5′→3′ end processing during homology-dependent DNA double-strand break repair.
- Published in:
- Journal of Cell Biology, 2011, v. 192, n. 2, p. 251, doi. 10.1083/jcb.201005110
- By:
- Publication type:
- Article