Works about MUTAGENESIS

Results: 5000

Mutagenesis Targeting the S 153 Residue Within the Transmembrane β-Hairpin of Mosquito-Larvicidal Mpp46Ab Affects Its Toxicity and the Synergistic Toxicity with Cry4Aa.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 489, doi. 10.3390/biology14050489

By:

Hayakawa, Tohru;
Yamaoka, Syun;
Asakura, Mami;
Hirano, Minako;
Ide, Toru

Publication type:

Article

Recent Advances and Achievements in Mutation Breeding of Fruit Crops: A Review.

Published in:

Agricultural Reviews, 2025, v. 46, n. 2, p. 220, doi. 10.18805/ag.R-2616

By:

Sebastian, Karishma;
Bindu, B.;
Arya, M. S.

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Article

Polymerase δ replicates both strands after homologous recombination-dependent fork restart.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 11, p. 932, doi. 10.1038/nsmb.3100

By:

Miyabe, Izumi;
Mizuno, Ken'Ichi;
Keszthelyi, Andrea;
Daigaku, Yasukazu;
Skouteri, Meliti;
Mohebi, Saed;
Kunkel, Thomas A;
Murray, Johanne M;
Carr, Antony M

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Article

Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 6, p. 485, doi. 10.1038/nsmb.3033

By:

Kouno, Takahide;
Luengas, Elizabeth M;
Shigematsu, Megumi;
Shandilya, Shivender M D;
Zhang, JingYing;
Chen, Luan;
Hara, Mayuko;
Schiffer, Celia A;
Harris, Reuben S;
Matsuo, Hiroshi

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Article

EF-G catalyzes tRNA translocation by disrupting interactions between decoding center and codon-anticodon duplex.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 9, p. 817, doi. 10.1038/nsmb.2869

By:

Liu, Guangqiao;
Song, Guangtao;
Zhang, Danyang;
Zhang, Dejiu;
Li, Zhikai;
Lyu, Zhixin;
Dong, Jianshu;
Achenbach, John;
Gong, Weimin;
Zhao, Xin Sheng;
Nierhaus, Knud H;
Qin, Yan

Publication type:

Article

The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 8, p. 679, doi. 10.1038/nsmb.2857

By:

Tan, Dazhi;
Zhou, Mi;
Kiledjian, Megerditch;
Tong, Liang

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Article

Mechanism of activation of bacterial cellulose synthase by cyclic di-GMP.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 489, doi. 10.1038/nsmb.2803

By:

Morgan, Jacob L W;
McNamara, Joshua T;
Zimmer, Jochen

Publication type:

Article

T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 480, doi. 10.1038/nsmb.2817

By:

Petersen, Jan;
Montserrat, Veronica;
Mujico, Jorge R;
Loh, Khai Lee;
Beringer, Dennis X;
van Lummel, Menno;
Thompson, Allan;
Mearin, M Luisa;
Schweizer, Joachim;
Kooy-Winkelaar, Yvonne;
van Bergen, Jeroen;
Drijfhout, Jan W;
Kan, Wan-Ting;
La Gruta, Nicole L;
Anderson, Robert P;
Reid, Hugh H;
Koning, Frits;
Rossjohn, Jamie

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Article

Structure and assembly of the NOT module of the human CCR4-NOT complex.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 11, p. 1289, doi. 10.1038/nsmb.2681

By:

Boland, Andreas;
Chen, Ying;
Raisch, Tobias;
Jonas, Stefanie;
Kuzuoğlu-Öztürk, Duygu;
Wohlbold, Lara;
Weichenrieder, Oliver;
Izaurralde, Elisa

Publication type:

Article

Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 515, doi. 10.1038/nsmb.2528

By:

Gleghorn, Michael L;
Gong, Chenguang;
Kielkopf, Clara L;
Maquat, Lynne E

Publication type:

Article

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 1, p. 59, doi. 10.1038/nsmb.2431

By:

Otomo, Chinatsu;
Metlagel, Zoltan;
Takaesu, Giichi;
Otomo, Takanori

Publication type:

Article

Visualizing transient protein-folding intermediates by tryptophan-scanning mutagenesis.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 7, p. 731, doi. 10.1038/nsmb.2322

By:

Vallée-Bélisle, Alexis;
Michnick, Stephen W

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Article

The structural basis of RNA-catalyzed RNA polymerization.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 1036, doi. 10.1038/nsmb.2107

By:

Shechner, David M.;
Bartel, David P.

Publication type:

Article

Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 8, p. 902, doi. 10.1038/nsmb.2079

By:

Pykäläinen, Anette;
Boczkowska, Malgorzata;
Hongxia Zhao;
Saarikangas, Juha;
Rebowski, Grzegorz;
Jansen, Maurice;
Hakanen, Janne;
Koskela, Essi V.;
Peränen, Johan;
Vihinen, Helena;
Jokitalo, Eija;
Salminen, Marjo;
Ikonen, Elina;
Dominguez, Roberto;
Lappalainen, Pekka

Publication type:

Article

A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 8, p. 947, doi. 10.1038/nsmb.2086

By:

Calabrese, Matthew F.;
Scott, Daniel C.;
Duda, David M.;
Grace, Christy R. R.;
Kurinov, Igor;
Kriwacki, Richard W.;
Schulman, Brenda A.

Publication type:

Article

Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 7, p. 846, doi. 10.1038/nsmb.2068

By:

Kosloff, Mickey;
Travis, Amanda M.;
Bosch, Dustin E.;
Siderovski, David P.;
Arshavsky, Vadim Y.

Publication type:

Article

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 6, p. 708, doi. 10.1038/nsmb.2059

By:

Martin, David;
Pantoja, Cristina;
Miñán, Ana Fernández;
Valdes-Quezada, Christian;
Moltó, Eduardo;
Matesanz, Fuencisla;
Bogdanović, Ozren;
de la Calle-Mustienes, Elisa;
Domínguez, Orlando;
Taher, Leila;
Furlan-Magaril, Mayra;
Alcina, Antonio;
Cañón, Susana;
Fedetz, María;
Blasco, María A;
Pereira, Paulo S;
Ovcharenko, Ivan;
Recillas-Targa, Félix;
Montoliu, Lluís;
Manzanares, Miguel

Publication type:

Article

mRNA translocation occurs during the second step of ribosomal intersubunit rotation.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 457, doi. 10.1038/nsmb.2011

By:

Ermolenko, Dmitri N.;
Noller, Harry F.

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Article

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 3, p. 270, doi. 10.1038/nsmb.1984

By:

Jeong Ho Chang;
Song Xiang;
Kehui Xiang;
Manley, James L.;
Liang Tong

Publication type:

Article

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 3, p. 316, doi. 10.1038/nsmb.2007

By:

Fairman, James Wesley;
Wijerathna, Sanath Ranjan;
Ahmad, Md Faiz;
Hai Xu;
Nakano, Ryo;
Jha, Shalini;
Prendergast, Jay;
Welin, R. Martin;
Flodin, Susanne;
Roos, Annette;
Nordlund, Pär;
Li, Zongli;
Walz, Thomas;
Dealwis, Chris Godfrey

Publication type:

Article

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 2, p. 177, doi. 10.1038/nsmb.1983

By:

Oberoi, Jasmeen;
Fairall, Louise;
Watson, Peter J.;
Ji-Chun Yang;
Czimmerer, Zsolt;
Kampmann, Thorsten;
Goult, Benjamin T.;
Greenwood, Jacquie A.;
Gooch, John T.;
Kallenberger, Bettina C.;
Nagy, Laszlo;
Neuhaus, David;
Schwabe, John W. R.

Publication type:

Article

Hybrid molecular structure of the giant protease tripeptidyl peptidase II.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 8, p. 990, doi. 10.1038/nsmb.1870

By:

Chuang, Crystal K.;
Rockel, Beate;
Seyit, Gönül;
Walian, Peter J.;
Schönegge, Anne-Marie;
Peters, Jürgen;
Zwart, Petrus H.;
Baumeister, Wolfgang;
Jap, Bing K.

Publication type:

Article

Crystal structure of the carnitine transporter and insights into the antiport mechanism.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 4, p. 492, doi. 10.1038/nsmb.1788

By:

Lin Tang;
Lin Bai;
Wen-hua Wang;
Tao Jiang

Publication type:

Article

Orthogonal use of a human tRNA synthetase active site to achieve multifunctionality.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 1, p. 57, doi. 10.1038/nsmb.1706

By:

Quansheng Zhou;
Kapoor, Mili;
Min Guo;
Belani, Rajesh;
Xiaoling Xu;
Kiosses, William B.;
Hanan, Melanie;
Chulho Park;
Armour, Eva;
Minh-Ha Do;
Nangle, Leslie A.;
Schimmel, Paul;
Xiang-Lei Yang

Publication type:

Article

THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 1, p. 117, doi. 10.1038/nsmb.1742

By:

Sabogal, Alex;
Lyubimov, Artem Y.;
Corn, Jacob E.;
Berger, James M.;
Rio, Donald C.

Publication type:

Article

Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 1, p. 130, doi. 10.1038/nsmb.1705

By:

sbreve, Dragana;
Miller, Marshall C.;
Quinkert, Zachary T.;
Stein, Markus;
Chait, Brian T.;
Stebbins, C. Erec

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Article

Solution structure and functional analysis of the influenza B proton channel.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 12, p. 1267, doi. 10.1038/nsmb.1707

By:

Junfeng Wang;
Pielak, Rafal M.;
McClintock, Mark A.;
Chou, James J.

Publication type:

Article

Following evolutionary paths to protein-protein interactions with high affinity and selectivity.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 10, p. 1049, doi. 10.1038/nsmb.1670

By:

Levin, Kalia Bernath;
Dym, Orly;
Albeck, Shira;
Magdassi, Shlomo;
Keeble, Anthony H.;
Kleanthous, Colin;
Tawfik, Dan S.

Publication type:

Article

Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 7, p. 698, doi. 10.1038/nsmb.1607

By:

Bishop, Benjamin;
Aricescu, A. Radu;
Harlos, Karl;
O'Callaghan, Chris A.;
Jones, E. Yvonne;
Siebold, Christian

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Article

Localized thermodynamic coupling between hydrogen bonding and microenvironment polarity substantially stabilizes proteins.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 7, p. 684, doi. 10.1038/nsmb.1610

By:

Jianmin Gao;
Bosco, Daryl A.;
Powers, Evan T.;
Kelly, Jeffery W.

Publication type:

Article

Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 7, p. 731, doi. 10.1038/nsmb.1625

By:

Lingdi Zhang;
Tao Xu;
Maeder, Corina;
Bud, Laura-Oana;
Shanks, James;
Nix, Jay;
Guthrie, Christine;
Pleiss, Jeffrey A;
Rui Zhao

Publication type:

Article

E2 interaction and dimerization in the crystal structure of TRAF6.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 6, p. 658, doi. 10.1038/nsmb.1605

By:

Yin, Qian;
Lin, Su-Chang;
Lamothe, Betty;
Lu, Miao;
Lo, Yu-Chih;
Hura, Gregory;
Zheng, Lixin;
Rich, Rebecca L.;
Campos, Alejandro D.;
Myszka, David G.;
Lenardo, Michael J.;
Darnay, Bryant G.;
Wu, Hao

Publication type:

Article

High-resolution structure of the open NaK channel.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 1, p. 30, doi. 10.1038/nsmb.1531

By:

Alam, Amer;
Youxing Jiang

Publication type:

Article

Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 10, p. 1031, doi. 10.1038/nsmb.1493

By:

Etzkorn, Manuel;
Kneuper, Holger;
Dünnwald, Pia;
Vijayan, Vinesh;
Krämer, Jens;
Griesinger, Christian;
Becker, Stefan;
Unden, Gottfried;
Baldus, Marc

Publication type:

Article

Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 10, p. 1067, doi. 10.1038/nsmb.1487

By:

Nitta, Ryo;
Okada, Tasushi;
Hirokawa, Nobutaka

Publication type:

Article

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 7, p. 738, doi. 10.1038/nsmb.1448

By:

Tang, Yong;
Holbert, Marc A.;
Wurtele, Hugo;
Meeth, Katrina;
Rocha, Walter;
Gharib, Marlene;
Jiang, Eva;
Thibault, Pierre;
Verrault, Alain;
Cole, Philip A.;
Marmorstein, Ronen

Publication type:

Article

DNA apurinic-apyrimidinic site binding and excision by endonuclease IV.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 515, doi. 10.1038/nsmb.1414

By:

Garcin, Elsa D.;
Hosfield, David J.;
Desai, Sunil A.;
Haas, Brian J.;
Björas, Magnar;
Cunningham, Richard P.;
Tainer, John A.

Publication type:

Article

Sequence-specific dynamics modulate recognition specificity in WW domains.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 4, p. 325, doi. 10.1038/nsmb1207

By:

Peng, Tao;
Zintsmaster, John S.;
Namanja, Andrew T.;
Peng, Jeffrey W.

Publication type:

Article

Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 4, p. 301, doi. 10.1038/nsmb1214

By:

Ribes-Zamora, Albert;
Mihalek, Ivana;
Lichtarge, Olivier;
Bertuch, Alison A.

Publication type:

Article

Single-molecule observations of neck linker conformational changes in the kinesin motor protein.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 10, p. 887, doi. 10.1038/nsmb1151

By:

Tomishige, Michio;
Stuurman, Nico;
Vale, Ronald D.

Publication type:

Article

Mms2–Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 10, p. 915, doi. 10.1038/nsmb1148

By:

Eddins, Michael J.;
Carlile, Candice M.;
Gomez, Kamila M.;
Pickart, Cecile M.;
Wolberger, Cynthia

Publication type:

Article

A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 9, p. 839, doi. 10.1038/nsmb1137

By:

Rideau, Alexis P.;
Gooding, Clare;
Simpson, Peter J.;
Monie, Tom P.;
Lorenz, Mike;
Hüttelmaier, Stefan;
Singer, Robert H.;
Matthews, Stephen;
Curry, Stephen;
Smith, Christopher W. J.

Publication type:

Article

Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 7, p. 582, doi. 10.1038/nsmb1105

By:

Khan, Javed A.;
Xiao Tao;
Liang Tong

Publication type:

Article

In vivo assembly of functional U7 snRNP requires RNA backbone flexibility within the Sm-binding site.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 4, p. 347, doi. 10.1038/nsmb1075

By:

Kolev, Nikolay G;
Steitz, Joan A

Publication type:

Article

Molecular recognition of p53 and MDM2 by USP7/HAUSP.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 3, p. 285, doi. 10.1038/nsmb1067

By:

Yi Sheng;
Saridakis, Vivian;
Sarkari, Feroz;
Duan, Shili;
Tianne Wu;
Arrowsmith, Cheryl H.;
Frappier, Lori

Publication type:

Article

Structure of the heterodimeric core primase.

Published in:

Nature Structural & Molecular Biology, 2005, v. 12, n. 12, p. 1137, doi. 10.1038/nsmb1013

By:

Si-Houy Lao-Sirieix;
Nookala, Ravi K.;
Roversi, Pietro;
Bell, Stephen D.;
Pellegrini, Luca

Publication type:

Article

Viral evolution: Fooling the coronavirus proofreading machinery.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 10, p. 662, doi. 10.1038/nrmicro3125

By:

Hofer, Ursula

Publication type:

Article

Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 7, p. 435, doi. 10.1038/nrmicro3033

By:

van Opijnen, Tim;
Camilli, Andrew

Publication type:

Article

Antimicrobials: Mismatch excels when ampicillin runs low.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 5, p. 298, doi. 10.1038/nrmicro3017

By:

Kåhrström, Christina Tobin

Publication type:

Article

Recombineering mycobacteria and their phages.

Published in:

Nature Reviews Microbiology, 2008, v. 6, n. 11, p. 851, doi. 10.1038/nrmicro2014

By:

van Kessel, Julia C.;
Marinelli, Laura J.;
Hatfull, Graham F.

Publication type:

Article