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Posttranslationally Acting Arginases Provide a Ribosomal Route to Non‐proteinogenic Ornithine Residues in Diverse Peptide Sequences.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 48, p. 21626, doi. 10.1002/ange.202008990
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- Article
Discovery of Small Molecules that Induce the Degradation of Huntingtin.
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- Angewandte Chemie, 2017, v. 129, n. 38, p. 11688, doi. 10.1002/ange.201706529
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- Publication type:
- Article
Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.
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- Angewandte Chemie, 2017, v. 129, n. 19, p. 5286, doi. 10.1002/ange.201611750
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- Publication type:
- Article
Midazolam Enhances Mutant Huntingtin Protein Accumulation via Impairment of Autophagic Degradation <bold>In Vitro</bold>.
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- Cellular Physiology & Biochemistry (Karger AG), 2018, v. 48, n. 2, p. 683, doi. 10.1159/000491895
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- Article
Novel therapeutic approaches for Parkinson's disease by targeting brain cholesterol homeostasis.
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- Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 7, p. 862, doi. 10.1093/jpp/rgaa063
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- Publication type:
- Article
Dermal Fibroblast Cell Line from a Patient with the Huntington's Disease as a Promising Model for Studying Disease Pathogenesis: Production and Characterization.
- Published in:
- Biochemistry (00062979), 2024, v. 89, n. 7, p. 1239, doi. 10.1134/S000629792407006X
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- Article
RNA Editing by ADAR Adenosine Deaminases in the Cell Models of CAG Repeat Expansion Diseases: Significant Effect of Differentiation from Stem Cells into Brain Organoids in the Absence of Substantial Influence of CAG Repeats on the Level of Editing.
- Published in:
- Biochemistry (00062979), 2024, v. 89, n. 8, p. 1474, doi. 10.1134/S0006297924080078
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- Publication type:
- Article
Focus on Molecular Functions of Anti-Aging Deacetylase SIRT3.
- Published in:
- Biochemistry (00062979), 2022, v. 87, n. 1, p. 21, doi. 10.1134/S0006297922010035
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- Article
Normalization of Calcium Balance in Striatal Neurons in Huntington's Disease: Sigma 1 Receptor as a Potential Target for Therapy.
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- Biochemistry (00062979), 2021, v. 86, n. 4, p. 471, doi. 10.1134/S0006297921040076
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- Publication type:
- Article
Neurodegenerative disorders: New Huntington disease target identified.
- Published in:
- Nature Reviews Drug Discovery, 2015, v. 14, n. 6, p. 386, doi. 10.1038/nrd4652
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- Article
Neurodegenerative disorders: Reversing Huntington's disease.
- Published in:
- 2012
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- Publication type:
- journal article
The composition of the polyglutamine-containing proteins influences their co-aggregation properties.
- Published in:
- Cell Biology International, 2010, v. 34, n. 9, p. 933, doi. 10.1042/CBI20090474
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- Publication type:
- Article
Protective Effects of Antagonism of Interleukin-1 Receptors in 3-nitropropionic Acid Provoked Huntington Disease-Related Symptoms.
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- International Journal of Pharmaceutical Research (09752366), 2021, v. 13, n. 1, p. 2090, doi. 10.31838/ijpr/2021.13.01.307
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- Publication type:
- Article
Huntington's Disease patients in the Department of Neurology CM UJ in Cracow - a model of physiotherapy.
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- Medical Rehabilitation / Rehabilitacja Medyczna, 2013, v. 17, n. 1, p. 26
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- Publication type:
- Article
Characterizing White Matter in Huntington's Disease.
- Published in:
- Movement Disorders Clinical Practice, 2020, v. 7, n. 1, p. 52, doi. 10.1002/mdc3.12866
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- Publication type:
- Article
Selection and characterization of llama single domain antibodies against N-terminal huntingtin.
- Published in:
- Neurological Sciences, 2015, v. 36, n. 3, p. 429, doi. 10.1007/s10072-014-1971-6
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- Publication type:
- Article
Nuclear localization of huntingtin during spermatogenesis.
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- Neurological Sciences, 2014, v. 35, n. 3, p. 459, doi. 10.1007/s10072-013-1515-5
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- Publication type:
- Article
Widespread alterations in microRNA biogenesis in human Huntington's disease putamen.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01407-7
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- Publication type:
- Article
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington's disease.
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- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01379-8
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- Publication type:
- Article
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington's disease.
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- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01379-8
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- Publication type:
- Article
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in huntington's disease.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01379-8
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- Publication type:
- Article
Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01333-8
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- Publication type:
- Article
Reappraisal of metabolic dysfunction in neurodegeneration: Focus on mitochondrial function and calcium signaling.
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- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01224-4
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- Publication type:
- Article
An update on the neurological short tandem repeat expansion disorders and the emergence of long-read sequencing diagnostics.
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- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01201-x
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- Publication type:
- Article
Towards an improved early diagnosis of neurodegenerative diseases: the emerging role of in vitro conversion assays for protein amyloids.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00990-x
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- Publication type:
- Article
No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00949-y
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- Publication type:
- Article
ISEV2024 Abstract Book.
- Published in:
- Journal of Extracellular Vesicles, 2024, v. 13, p. 1, doi. 10.1002/jev2.12444
- Publication type:
- Article
MicroRNA editing patterns in Huntington's disease.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-06970-6
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- Publication type:
- Article
Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-98661-x
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- Article
The Vasopressin 1a Receptor Antagonist SRX246 Reduces Aggressive Behavior in Huntington's Disease.
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- Journal of Personalized Medicine, 2022, v. 12, n. 10, p. 1561, doi. 10.3390/jpm12101561
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- Publication type:
- Article
Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin.
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- Journal of Personalized Medicine, 2021, v. 11, n. 12, p. 1309, doi. 10.3390/jpm11121309
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- Publication type:
- Article
Proteotoxicity: A Fatal Consequence of Environmental Pollutants-Induced Impairments in Protein Clearance Machinery.
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- Journal of Personalized Medicine, 2021, v. 11, n. 2, p. 69, doi. 10.3390/jpm11020069
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- Publication type:
- Article
The MID1 Protein: A Promising Therapeutic Target in Huntington's Disease.
- Published in:
- Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.761714
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- Article
An Optimization of AAV-82Q-Delivered Rat Model of Huntington's Disease.
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- Journal of Korean Neurosurgical Society, 2020, v. 63, n. 5, p. 579, doi. 10.3340/jkns.2019.0182
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- Article
Uncovering the mechanism for aggregation in repeat expanded RNA reveals a reentrant transition.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-35803-x
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- Publication type:
- Article
Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32370-5
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- Publication type:
- Article
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30418-0
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- Publication type:
- Article
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30418-0
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- Publication type:
- Article
Towards Personalized Allele-Specific Antisense Oligonucleotide Therapies for Toxic Gain-of-Function Neurodegenerative Diseases.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 8, p. 1708, doi. 10.3390/pharmaceutics14081708
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- Publication type:
- Article
Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer's Disease.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/pharmaceutics14071354
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- Publication type:
- Article
Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression.
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- Pharmaceutics, 2021, v. 13, n. 12, p. 2109, doi. 10.3390/pharmaceutics13122109
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- Publication type:
- Article
New Perspectives of Gene Therapy on Polyglutamine Spinocerebellar Ataxias: From Molecular Targets to Novel Nanovectors.
- Published in:
- Pharmaceutics, 2021, v. 13, n. 7, p. 1018, doi. 10.3390/pharmaceutics13071018
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- Publication type:
- Article
A Combinatorial Cell and Drug Delivery Strategy for Huntington's Disease Using Pharmacologically Active Microcarriers and RNAi Neuronally-Committed Mesenchymal Stromal Cells.
- Published in:
- Pharmaceutics, 2019, v. 11, n. 10, p. 526, doi. 10.3390/pharmaceutics11100526
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- Publication type:
- Article
An Innovative Approach to Address Neurodegenerative Diseases through Kinase-Targeted Therapies: Potential for Designing Covalent Inhibitors.
- Published in:
- Pharmaceuticals (14248247), 2023, v. 16, n. 9, p. 1295, doi. 10.3390/ph16091295
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- Publication type:
- Article
The Disruption of NMDAR/TRPM4 Death Signaling with TwinF Interface Inhibitors: A New Pharmacological Principle for Neuroprotection.
- Published in:
- Pharmaceuticals (14248247), 2023, v. 16, n. 8, p. 1085, doi. 10.3390/ph16081085
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- Publication type:
- Article
Extracellular Vesicle Delivery of Neferine for the Attenuation of Neurodegenerative Disease Proteins and Motor Deficit in an Alzheimer's Disease Mouse Model.
- Published in:
- Pharmaceuticals (14248247), 2022, v. 15, n. 1, p. 83, doi. 10.3390/ph15010083
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- Publication type:
- Article
New Treatment Reduces Levels of Protein Linked to Huntington Disease.
- Published in:
- Psychiatric Times, 2019, v. 36, n. 7, p. 6
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- Publication type:
- Article
Psychiatric and cognitive symptoms in Huntington's disease are modified by polymorphisms in catecholamine regulating enzyme genes.
- Published in:
- Clinical Genetics, 2016, v. 89, n. 3, p. 320, doi. 10.1111/cge.12628
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- Publication type:
- Article
The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington's disease.
- Published in:
- BMC Research Notes, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13104-020-05053-x
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- Publication type:
- Article
The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin Function.
- Published in:
- Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00253
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- Publication type:
- Article