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Intestinal flora and bile acid interactions impact the progression of diabetic kidney disease.
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- Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1441415
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- Article
Profiling and Identification of Biocatalyzed Transformation of Sulfoxaflor In Vivo.
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- Angewandte Chemie, 2020, v. 132, n. 37, p. 16352, doi. 10.1002/ange.202007079
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- Article
Nuclear receptors: a bridge linking the gut microbiome and the host.
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- Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00407-y
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- Article
Pathophysiology of reflux oesophagitis: role of Toll-like receptors 2 and 4 and Farnesoid X receptor.
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- Virchows Archiv: European Journal of Pathology, 2021, v. 479, n. 2, p. 285, doi. 10.1007/s00428-021-03066-w
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- Article
Farnesoid X receptor (FXR) agonist ameliorates systemic insulin resistance, dysregulation of lipid metabolism, and alterations of various organs in a type 2 diabetic kidney animal model.
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- Acta Diabetologica, 2021, v. 58, n. 4, p. 495, doi. 10.1007/s00592-020-01652-z
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- Article
FXR Acts as a Metastasis Suppressor in Intrahepatic Cholangiocarcinoma by Inhibiting IL-6-Induced Epithelial-Mesenchymal Transition.
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- Cellular Physiology & Biochemistry (Karger AG), 2018, v. 48, n. 1, p. 158, doi. 10.1159/000491715
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- Article
Farnesoid X Receptor (FXR) Interacts with Camp Response Element Binding Protein (CREB) to Modulate Glucagon-Like Peptide-1 (7–36) Amide (GLP-1) Secretion by Intestinal L Cell.
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- Cellular Physiology & Biochemistry (Karger AG), 2018, v. 47, n. 4, p. 1442, doi. 10.1159/000490836
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- Article
Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus Infection.
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- Cellular Physiology & Biochemistry (Karger AG), 2017, v. 41, n. 1, p. 323, doi. 10.1159/000456168
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- Article
Genipin improves obesity through promoting bile secretion and changing bile acids composition in diet-induced obese rats.
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- Journal of Pharmacy & Pharmacology, 2024, v. 76, n. 7, p. 897, doi. 10.1093/jpp/rgae055
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- Article
H<sub>2</sub>S inhibits apo(a) expression and secretion through PKCα/FXR and Akt/HNF4α pathways in HepG2 cells.
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- Cell Biology International, 2016, v. 40, n. 8, p. 906, doi. 10.1002/cbin.10632
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Dynamic changes of serum protein in rats with acute intoxication of Chinese cobra snake venom by proteomic analysis.
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- Forensic Sciences Research, 2020, v. 5, n. 4, p. 309, doi. 10.1080/20961790.2017.1405565
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- Article
Diminished Tubule Epithelial Farnesoid X Receptor Expression Exacerbates Inflammation and Fibrosis Response in Aged Rat Kidney.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2023, v. 78, n. 1, p. 60, doi. 10.1093/gerona/glac148
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- Article
Farnesoid X Receptor-Mediated Cytoplasmic Translocation of CRTC2 Disrupts CREB-BDNF Signaling in Hippocampal CA1 and Leads to the Development of Depression-Like Behaviors in Mice.
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- International Journal of Neuropsychopharmacology, 2020, v. 23, n. 10, p. 673, doi. 10.1093/ijnp/pyaa039
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- Article
G蛋白偶联胆汁酸受体1促进胃癌细胞的增殖、迁移和侵袭的实验研究.
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- Progress in Modern Biomedicine, 2022, v. 22, n. 1, p. 32, doi. 10.13241/j.cnki.pmb.2022.01.006
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- Article
激活 FXR 抑制结肠癌细胞浸润转移及 MMP-7 的表达.
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- Progress in Modern Biomedicine, 2018, v. 18, n. 24, p. 4633, doi. 10.13241/j.cnki.pmb.2018.24.006
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- Article
THE FARNESOID X RECEPTOR: A NOVEL TARGET FOR HEPATOCELLULAR CARCINOMA.
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- Meducator, 2020, n. 37, p. 5
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- Article
糖肾方调控 FXR / vimentin / α-SMA 通路减轻糖尿病 肾脏疾病肾脏纤维化的研究.
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- Journal of Beijing University of Traditional Chinese Medicine, 2022, n. 12, p. 1196, doi. 10.3969/j.issn.1006-2157.2022.12.003
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Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles.
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- Journal of Extracellular Vesicles, 2022, v. 11, n. 4, p. 1, doi. 10.1002/jev2.12211
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- Article
FXR Mediates Adenylyl Cyclase 8 Expression in Pancreatic β-Cells.
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- Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/8915818
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- Article
TGR5 agonists induce peripheral and central hypersensitivity to bladder distension.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-14195-w
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- Article
FXR expression in rats of hilar cholangiocarcinoma.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-12850-w
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- Article
A single faecal bile acid stool test demonstrates potential efficacy in replacing SeHCAT testing for bile acid diarrhoea in selected patients.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-12003-z
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- Article
Bile acids attenuate PKM2 pathway activation in proinflammatory microglia.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05408-3
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- Article
Bile acids attenuate PKM2 pathway activation in proinflammatory microglia.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05408-3
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- Article
PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04524-w
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- Article
Hypoglycemic mechanism of intestinal bypass surgery in type 2 diabetic rats.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-98714-1
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- Article
Influence of the Bile Acid Transporter Genes ABCB4 , ABCB8 , and ABCB11 and the Farnesoid X Receptor on the Response to Ursodeoxycholic Acid in Patients with Nonalcoholic Steatohepatitis.
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- Journal of Personalized Medicine, 2023, v. 13, n. 7, p. 1180, doi. 10.3390/jpm13071180
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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Non–Bile Acid FXR Agonist Tropifexor (LJN452) in Healthy Volunteers.
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- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 3, p. 395, doi. 10.1002/cpdd.762
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Vitamin C and vitamin D<sub>3</sub> alleviate metabolic-associated fatty liver disease by regulating the gut microbiota and bile acid metabolism via the gut-liver axis.
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- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1163694
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Geniposide plus chlorogenic acid reverses non-alcoholic steatohepatitis via regulation of gut microbiota and bile acid signaling in a mouse model in vivo.
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- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1148737
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Effect of mTOR inhibitors on sodium taurocholate cotransporting polypeptide (NTCP) function in vitro.
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- Frontiers in Pharmacology, 2023, v. 14, p. 01, doi. 10.3389/fphar.2023.1147495
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Polygoni Multiflori Radix interferes with bile acid metabolism homeostasis by inhibiting Fxr transcription, leading to cholestasis.
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- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1099935
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Krüppel-like factor 15 in liver diseases: Insights into metabolic reprogramming.
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- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1115226
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The ameliorating effect of withaferin A on high-fat diet-induced non-alcoholic fatty liver disease by acting as an LXR/FXR dual receptor activator.
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- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1135952
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The regulatory effects of second-generation antipsychotics on lipid metabolism: Potential mechanisms mediated by the gut microbiota and therapeutic implications.
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- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1097284
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- Article
Paeoniflorin alleviates 17α-ethinylestradiol-induced cholestasis via the farnesoid X receptor-mediated bile acid homeostasis signaling pathway in rats.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1064653
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- Article
Ginsenoside Rc attenuates DSS-induced ulcerative colitis, intestinal inflammatory, and barrier function by activating the farnesoid X receptor.
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- Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.1000444
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Chaihu-shugan-san alleviates depression-like behavior in mice exposed to chronic unpredictable stress by altering the gut microbiota and levels of the bile acids hyocholic acid and 7-ketoDCA.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1040591
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Farnesoid-X receptor as a therapeutic target for inflammatory bowel disease and colorectal cancer.
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- Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.1016836
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Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARa-SREBPs pathway.
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- Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.1007274
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PPARα: A potential therapeutic target of cholestasis.
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- Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.916866
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The Effect of Lithocholic Acid on the Gut-Liver Axis.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.910493
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Theabrownin and Poria cocos Polysaccharide Improve Lipid Metabolism via Modulation of Bile Acid and Fatty Acid Metabolism.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.875549
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Multi-Omics Reveals Inhibitory Effect of Baicalein on Non-Alcoholic Fatty Liver Disease in Mice.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.925349
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Effects of Intestinal FXR-Related Molecules on Intestinal Mucosal Barriers in Biliary Tract Obstruction.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.906452
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Screening of Biomarkers and Toxicity Mechanisms of Rifampicin-Induced Liver Injury Based on Targeted Bile Acid Metabolomics.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.925509
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Obeticholic Acid Induces Hepatoxicity Via FXR in the NAFLD Mice.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.880508
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Discovery of a Potent and Orally Active Dual GPBAR1/CysLT<sub>1</sub>R Modulator for the Treatment of Metabolic Fatty Liver Disease.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.858137
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Da-Chai-Hu-Tang Protects From Acute Intrahepatic Cholestasis by Inhibiting Hepatic Inflammation and Bile Accumulation via Activation of PPARα.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.847483
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Bibliometric analysis of research on gut microbiota and bile acids: publication trends and research frontiers.
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- Frontiers in Microbiology, 2024, p. 1, doi. 10.3389/fmicb.2024.1433910
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- Article