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Applications of graph theory in studying protein structure, dynamics, and interactions.
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- Journal of Mathematical Chemistry, 2024, v. 62, n. 10, p. 2562, doi. 10.1007/s10910-023-01511-6
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- Article
Tandem Domains with Tuned Interactions Are a Powerful Biological Design Principle.
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- PLoS Biology, 2015, v. 13, n. 12, p. 1, doi. 10.1371/journal.pbio.1002306
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- Article
NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment.
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- Angewandte Chemie, 2021, v. 133, n. 48, p. 25632, doi. 10.1002/ange.202109965
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- Article
From Selection to Instruction and Back: Competing Conformational Selection and Induced Fit Pathways in Abiotic Hosts.
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- Angewandte Chemie, 2021, v. 133, n. 36, p. 20095, doi. 10.1002/ange.202107091
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- Article
Comprehensive Analysis of Binding Sites in Tubulin.
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- Angewandte Chemie, 2021, v. 133, n. 24, p. 13443, doi. 10.1002/ange.202100273
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- Article
Activation of the G‐Protein‐Coupled Receptor Rhodopsin by Water.
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- Angewandte Chemie, 2021, v. 133, n. 5, p. 2318, doi. 10.1002/ange.202003342
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- Article
Multivalent Crown Ether Receptors Enable Allosteric Regulation of Anion Exchange in an Fe<sub>4</sub>L<sub>6</sub> Tetrahedron.
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- Angewandte Chemie, 2018, v. 130, n. 43, p. 14317, doi. 10.1002/ange.201808534
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- Article
Universality of the Sodium Ion Binding Mechanism in Class A G‐Protein‐Coupled Receptors.
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- Angewandte Chemie, 2018, v. 130, n. 12, p. 3102, doi. 10.1002/ange.201708889
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- Article
Multiple Binding Sites Contribute to the Mechanism of Mixed Agonistic and Positive Allosteric Modulators of the Cannabinoid CB1 Receptor.
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- Angewandte Chemie, 2018, v. 130, n. 10, p. 2610, doi. 10.1002/ange.201708764
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- Publication type:
- Article
Allosteric Tuning of Caspase-7: A Fragment-Based Drug Discovery Approach.
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- Angewandte Chemie, 2017, v. 129, n. 46, p. 14635, doi. 10.1002/ange.201706959
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- Article
Designed Spiroketal Protein Modulation.
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- Angewandte Chemie, 2017, v. 129, n. 20, p. 5572, doi. 10.1002/ange.201612504
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- Publication type:
- Article
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation.
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- Angewandte Chemie, 2016, v. 128, n. 38, p. 11749, doi. 10.1002/ange.201606242
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- Publication type:
- Article
Allosterically Regulated Phosphatase Activity from Peptide-PNA Conjugates Folded Through Hybridization.
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- Angewandte Chemie, 2016, v. 128, n. 30, p. 8737, doi. 10.1002/ange.201602751
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- Publication type:
- Article
The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex.
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- Angewandte Chemie, 2016, v. 128, n. 25, p. 7292, doi. 10.1002/ange.201603254
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- Publication type:
- Article
Handling complexity in biological interactions: Allostery and cooperativity in proteins.
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- Journal of Thermal Analysis & Calorimetry, 2019, v. 138, n. 5, p. 3229, doi. 10.1007/s10973-019-08610-0
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- Article
An integrated approach to study the molecular aspects of regulatory peptides biological mechanism.
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- Journal of Labelled Compounds & Radiopharmaceuticals, 2019, v. 62, n. 12, p. 812, doi. 10.1002/jlcr.3785
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- Article
Calcimimetic and Calcilytic Drugs: Feats, Flops, and Futures.
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- 2016
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- Publication type:
- journal article
Screening for hepatitis C virus non-nucleotide resistance mutations in treatment-naive women.
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- Journal of Antimicrobial Chemotherapy (JAC), 2009, v. 64, n. 5, p. 945, doi. 10.1093/jac/dkp328
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- Publication type:
- Article
Allostery in oligomeric receptor models.
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- Mathematical Medicine & Biology: A Journal of the IMA, 2020, v. 37, n. 3, p. 313, doi. 10.1093/imammb/dqz016
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- Publication type:
- Article
Effect of Structure Variations in the Inter-subunit Contact Zone on the Activity and Allosteric Regulation of Inorganic Pyrophosphatase from Mycobacterium tuberculosis.
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- Biochemistry (00062979), 2020, v. 85, n. 3, p. 326, doi. 10.1134/S0006297920030086
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- Article
The ribosome as an allosterically regulated molecular machine.
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- Biochemistry (00062979), 2017, v. 82, n. 13, p. 1557, doi. 10.1134/S0006297917130016
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- Article
Molecular dynamics investigation of a mechanism of allosteric signal transmission in ribosomes.
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- Biochemistry (00062979), 2015, v. 80, n. 8, p. 1047, doi. 10.1134/S0006297915080106
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- Publication type:
- Article
Influence of placental mannose/N-acetyl glucosamine-binding proteins on the interaction of insulin and insulin-like growth factors with their receptors.
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- Biochemistry (00062979), 2011, v. 76, n. 9, p. 1003, doi. 10.1134/S0006297911090033
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- Article
Protein structure analysis of abnormal hemoglobins; Hb D-Los Angeles, Hb S and Hb G-Coushatta.
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- Medicine Science, 2024, v. 13, n. 2, p. 289, doi. 10.5455/medscience.2024.01.06
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- Article
Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.
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- Nature Reviews Drug Discovery, 2014, v. 13, n. 9, p. 692, doi. 10.1038/nrd4308
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- Article
Emerging paradigms in GPCR allostery: implications for drug discovery.
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- Nature Reviews Drug Discovery, 2013, v. 12, n. 8, p. 630, doi. 10.1038/nrd4052
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- Article
Neurodevelopmental disorders: Glutamate blockers show benefit in models of autism spectrum disorders.
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- 2012
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- Publication type:
- journal article
Multiple sclerosis: Putting a dampener on inflammation.
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- 2010
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- Publication type:
- journal article
Kinase inhibitors: A winning combination against BCR–ABL.
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- Nature Reviews Drug Discovery, 2010, v. 9, n. 3, p. 194, doi. 10.1038/nrd3119
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- Publication type:
- Article
Anticancer drugs: Actively targeting mTOR.
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- Nature Reviews Drug Discovery, 2010, v. 9, n. 3, p. 193, doi. 10.1038/nrd3118
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- Article
Lead discovery: Enhancing cognition through PDE4 regulation.
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- Nature Reviews Drug Discovery, 2010, v. 9, n. 2, p. 106, doi. 10.1038/nrd3105
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- Article
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.
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- 2009
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- Publication type:
- journal article
Positive Allosteric Modulation of α5-GABAA Receptors Reverses Stress-Induced Alterations in Dopamine System Function and Prepulse Inhibition of Startle.
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- International Journal of Neuropsychopharmacology, 2022, v. 25, n. 8, p. 688, doi. 10.1093/ijnp/pyac035
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- Publication type:
- Article
Widespread Changes in Positive Allosteric Modulation of the Muscarinic M<sub>1</sub> Receptor in Some Participants With Schizophrenia.
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- International Journal of Neuropsychopharmacology, 2019, v. 22, n. 10, p. 640, doi. 10.1093/ijnp/pyz045
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- Article
Neurobiological Insights from mGlu Receptor Allosteric Modulation.
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- International Journal of Neuropsychopharmacology, 2016, v. 19, n. 5, p. 1, doi. 10.1093/ijnp/pyv133
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- Publication type:
- Article
Behavioral Effects of the Benzodiazepine-Positive Allosteric Modulator SH-053-2'F-S-CH3 in an Immune- Mediated Neurodevelopmental Disruption Model.
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- International Journal of Neuropsychopharmacology, 2015, p. 1, doi. 10.1093/ijnp/pyu055
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- Article
The potent M<sub>1</sub> receptor allosteric agonist GSK1034702 improves episodic memory in humans in the nicotine abstinence model of cognitive dysfunction.
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- International Journal of Neuropsychopharmacology, 2013, v. 16, n. 4, p. 721, doi. 10.1017/S1461145712000752
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- Article
Widespread decreases in cortical muscarinic receptors in a subset of people with schizophrenia.
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- International Journal of Neuropsychopharmacology, 2013, v. 16, n. 1, p. 37, doi. 10.1017/S1461145712000028
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- Publication type:
- Article
Galantamine ameliorates the impairment of recognition memory in mice repeatedly treated with methamphetamine: involvement of allosteric potentiation of nicotinic acetylcholine receptors and dopaminergic-ERK1/2 systems.
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- International Journal of Neuropsychopharmacology, 2010, v. 13, n. 10, p. 1343, doi. 10.1017/S1461145710000222
- Publication type:
- Article
Allosteric modulation of the effect of escitalopram, paroxetine and fluoxetine: in-vitro and in-vivo studies.
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- International Journal of Neuropsychopharmacology, 2007, v. 10, n. 1, p. 31, doi. 10.1017/S1461145705006462
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- Article
High‐resolution double vision of the allosteric phosphatase PTP1B.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2024, v. 80, n. 1, p. 1, doi. 10.1107/S2053230X23010749
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- Publication type:
- Article
Pharmacological properties of acid N-thiazolylamide FFA2 agonists.
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- Pharmacology Research & Perspectives, 2015, v. 3, n. 3, p. 1, doi. 10.1002/prp2.141
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- Publication type:
- Article
Preclinical evaluation of the antipsychotic potential of the mGlu2-positive allosteric modulator JNJ-40411813.
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- Pharmacology Research & Perspectives, 2015, v. 3, n. 2, p. n/a, doi. 10.1002/prp2.97
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- Publication type:
- Article
Use of a novel rapid and resource-efficient cassette dosing approach to determine the pharmacokinetics and CNS distribution of small molecule 7-transmembrane receptor allosteric modulators in rat.
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- Pharmacology Research & Perspectives, 2014, v. 2, n. 6, p. n/a, doi. 10.1002/prp2.77
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- Publication type:
- Article
Behavioral effects of the cannabinoid CB<sub>1</sub> receptor allosteric modulator ORG27569 in rats.
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- Pharmacology Research & Perspectives, 2014, v. 2, n. 6, p. n/a, doi. 10.1002/prp2.69
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- Publication type:
- Article
Beyond In Vitro Data: A Review of In Vivo Evidence Regarding the Allosteric Potentiating Effect of Galantamine on Nicotinic Acetylcholine Receptors in Alzheimer's Neuropathology.
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- Journal of Alzheimer's Disease, 2007, v. 11, n. 4, p. 491, doi. 10.3233/JAD-2007-11411
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- Article
The role of cysteine residues in the allosteric modulation of the chromophore phototransformations of biphotochromic fluorescent protein SAASoti.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03634-9
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- Publication type:
- Article
Molecular modelling approaches predicted 1,2,3-triazolyl ester of ketorolac (15K) to be a novel allosteric modulator of the oncogenic kinase PAK1.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-96817-3
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- Publication type:
- Article
Positive allosteric adenosine A<sub>2A</sub> receptor modulation suppresses insomnia associated with mania-and schizophrenia-like behaviors in mice.
- Published in:
- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1138666
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- Article
Unravelling the allosteric binding mode of αD-VxXXB at nicotinic acetylcholine receptors.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1170514
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- Publication type:
- Article