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Streamlined and Robust Stage-Specific Profiling of Gametocytocidal Compounds Against Plasmodium falciparum.
Published in:
Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.926460
By:
- Reader, Janette;
- van der Watt, Mariette E.;
- Birkholtz, Lyn-Marié
Publication type:
Article
Adapt or Die: Targeting Unique Transmission-Stage Biology for Malaria Elimination.
Published in:
Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.901971
By:
- van der Watt, Mariëtte E.;
- Reader, Janette;
- Birkholtz, Lyn-Marié
Publication type:
Article
New Transmission‐Selective Antimalarial Agents through Hit‐to‐Lead Optimization of 2‐([1,1′‐Biphenyl]‐4‐carboxamido)benzoic Acid Derivatives.
Published in:
ChemBioChem, 2022, v. 23, n. 21, p. 1, doi. 10.1002/cbic.202200427
By:
- Reader, Janette;
- Opperman, Daniel F. L.;
- van der Watt, Mariëtte E.;
- Theron, Anjo;
- Leshabane, Meta;
- da Rocha, Shanté;
- Turner, Jonathan;
- Garrabrant, Kathleen;
- Piña, Ivett;
- Mills, Catherine;
- Woster, Patrick M.;
- Birkholtz, Lyn‐Marié
Publication type:
Article
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites.
Published in:
Communications Chemistry, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42004-018-0062-7
By:
- Beteck, Richard M.;
- Seldon, Ronnett;
- Coertzen, Dina;
- van der Watt, Mariëtte E.;
- Reader, Janette;
- Mackenzie, Jared S.;
- Lamprecht, Dirk A.;
- Abraham, Matthew;
- Eribez, Korina;
- Müller, Joachim;
- Rui, Feng;
- Zhu, Guang;
- de Grano, Ruel Valerio;
- Williams, Ian D.;
- Smit, Frans J.;
- Steyn, Adrie J. C.;
- Winzeler, Elizabeth A.;
- Hemphill, Andrew;
- Birkholtz, Lyn-Marie;
- Warner, Digby F.
Publication type:
Article
Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.
Published in:
ChemMedChem, 2017, v. 12, n. 24, p. 2086, doi. 10.1002/cmdc.201700599
By:
- Harmse, Rozanne;
- Coertzen, Dina;
- Wong, Ho Ning;
- Smit, Frans J.;
- van der Watt, Mariette E.;
- Reader, Janette;
- Nondaba, Sindiswe H.;
- Birkholtz, Lyn‐Marie;
- Haynes, Richard K.;
- N'Da, David D.
Publication type:
Article
Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials.
Published in:
2018
By:
- van der Watt, Mariëtte E.;
- Reader, Janette;
- Churchyard, Alisje;
- Nondaba, Sindisiwe H.;
- Lauterbach, Sonja B.;
- Niemand, Jandeli;
- Abayomi, Sijuade;
- van Biljon, Riëtte A.;
- Connacher, Jessica I.;
- van Wyk, Roelof D. J.;
- Le Manach, Claire;
- Paquet, Tanya;
- González Cabrera, Diego;
- Brunschwig, Christel;
- Theron, Anjo;
- Lozano-Arias, Sonia;
- Rodrigues, Janneth F. I.;
- Herreros, Esperanza;
- Leroy, Didier;
- Duffy, James
Publication type:
journal article
Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20629-8
By:
- Reader, Janette;
- van der Watt, Mariëtte E.;
- Taylor, Dale;
- Le Manach, Claire;
- Mittal, Nimisha;
- Ottilie, Sabine;
- Theron, Anjo;
- Moyo, Phanankosi;
- Erlank, Erica;
- Nardini, Luisa;
- Venter, Nelius;
- Lauterbach, Sonja;
- Bezuidenhout, Belinda;
- Horatscheck, Andre;
- van Heerden, Ashleigh;
- Spillman, Natalie J.;
- Cowell, Anne N.;
- Connacher, Jessica;
- Opperman, Daniel;
- Orchard, Lindsey M.
Publication type:
Article

Found: 7

Streamlined and Robust Stage-Specific Profiling of Gametocytocidal Compounds Against Plasmodium falciparum.

Adapt or Die: Targeting Unique Transmission-Stage Biology for Malaria Elimination.

New Transmission‐Selective Antimalarial Agents through Hit‐to‐Lead Optimization of 2‐([1,1′‐Biphenyl]‐4‐carboxamido)benzoic Acid Derivatives.

Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites.

Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.

Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials.

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box.