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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Published in:
2010
By:
- Rouschop, Kasper M. A.;
- van den Beucken, Twan;
- Dubois, Ludwig;
- Niessen, Hanneke;
- Bussink, Johan;
- Savelkouls, Kim;
- Keulers, Tom;
- Mujcic, Hilda;
- Landuyt, Willy;
- Voncken, Jan Willem;
- Lambin, Philippe;
- van der Kogel, Albert J.;
- Koritzinsky, Marianne;
- Wouters, Bradly G.
Publication type:
journal article
Clinical Outcome and Tumour Microenvironmental Effects of Accelerated Radiotherapy with Carbogen and Nicotinamide.
Published in:
Acta Oncologica, 1999, v. 38, n. 7, p. 875, doi. 10.1080/028418699432563
By:
- Bussink, Johan;
- Kaanders, Johannes H. A. M.;
- van der Kogel, Albert J.
Publication type:
Article
Tumor microenvironment in head and neck squamous cell carcinomas: Predictive value and clinical relevance of hypoxic markers. A review.
Published in:
Head & Neck, 2007, v. 29, n. 6, p. 591, doi. 10.1002/hed.20543
By:
- Hoogsteen, Ilse J.;
- Marres, Henri A. M.;
- Bussink, Johan;
- van der Kogel, Albert J.;
- Kaanders, Johannes H. A. M.
Publication type:
Article
Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines.
Published in:
Molecular Cancer, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1476-4598-12-133
By:
- Stegeman, Hanneke;
- Kaanders, Johannes H. A. M.;
- Verheijen, Marieke M. G.;
- Peeters, Wenny J. M.;
- Wheeler, Deric L.;
- Iida, Mari;
- Grénman, Reidar;
- Van der Kogel, Albert J.;
- Span, Paul N.;
- Bussink, Johan
Publication type:
Article
(64)Cu-ATSM and (18)FDG PET uptake and (64)Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry.
Published in:
2012
By:
- Hansen, Anders E;
- Kristensen, Annemarie T;
- Jørgensen, Jesper T;
- McEvoy, Fintan J;
- Busk, Morten;
- van der Kogel, Albert J;
- Bussink, Johan;
- Engelholm, Svend A;
- Kjær, Andreas
Publication type:
journal article
Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer.
Published in:
Radiation Oncology, 2012, v. 7, n. 1, p. 75, doi. 10.1186/1748-717X-7-75
By:
- R�e, Kathrine;
- Mikalsen, Lars T. G.;
- van der Kogel, Albert J.;
- Bussink, Johan;
- Lyng, Heidi;
- Ree, Anne H.;
- Marignol, Laure;
- Olsen, Dag R.
Publication type:
Article
Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry.
Published in:
2003
By:
- Robinson, Simon P.;
- Rijken, Paul F.J.W.;
- Howe, Franklyn A.;
- McSheehy, Paul M.J.;
- van der Sanden, Boudewijn P.J.;
- Heerschap, Arend;
- Stubbs, Marion;
- van der Kogel, Albert J.;
- Griffiths, John R.
Publication type:
journal article
Method for quantitative mapping of dynamic MRI contrast agent uptake in human tumors.
Published in:
2001
By:
- Rijpkema, Mark;
- Kaanders, Johannes H.A.M.;
- Joosten, Frank B.M.;
- van der Kogel, Albert J.;
- Heerschap, Arend;
- Rijpkema, M;
- Kaanders, J H;
- Joosten, F B;
- van der Kogel, A J;
- Heerschap, A
Publication type:
journal article
Transcriptional response to hypoxia in human tumors.
Published in:
2001
By:
- Lal, Anita;
- Peters, Hans;
- Croix, Brad St.;
- Haroon, Zishan A.;
- Dewhirst, Mark W.;
- Strausberg, Robert L.;
- Kaanders, Johannes H.A.M.;
- van der Kogel, Albert J.;
- Riggins, Gregory J.;
- Lal, A;
- Peters, H;
- St Croix, B;
- Haroon, Z A;
- Dewhirst, M W;
- Strausberg, R L;
- Kaanders, J H;
- van der Kogel, A J;
- Riggins, G J
Publication type:
journal article
A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis.
Published in:
Oncogene, 2002, v. 21, n. 2, p. 282, doi. 10.1038/sj.onc.1205047
By:
- Williams, Kaye J.;
- Tefler, Brian A.;
- Airley, Rachel E.;
- Peters, Hans PW;
- Sheridan, Mary R.;
- van der Kogel, Albert J.;
- Harris, Adrian L.;
- Stratford, Ian J.
Publication type:
Article
Correlation of [18F]FMISO autoradiography and pimonodazole immunohistochemistry in human head and neck carcinoma xenografts.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2008, v. 35, n. 10, p. 1803, doi. 10.1007/s00259-008-0772-7
By:
- Troost, Esther G. C.;
- Laverman, Peter;
- Philippens, Mariëlle E. P.;
- Lok, Jasper;
- van der Kogel, Albert J.;
- Oyen, Wim J. G.;
- Boerman, Otto C.;
- Kaanders, Johannes H. A. M.;
- Bussink, Johan
Publication type:
Article
Aerobic glycolysis in cancers: Implications for the usability of oxygen-responsive genes and fluorodeoxyglucose-PET as markers of tissue hypoxia.
Published in:
International Journal of Cancer, 2008, v. 122, n. 12, p. 2726, doi. 10.1002/ijc.23449
By:
- Busk, Morten;
- Horsman, Michael R.;
- Kristjansen, Paul E.G.;
- van der Kogel, Albert J.;
- Bussink, Johan;
- Overgaard, Jens
Publication type:
Article
Phenotypic and Genotypic Characterization of Orthotopic Human Glioma Models and Its Relevance for the Study of Anti-glioma Therapy.
Published in:
Brain Pathology, 2008, v. 18, n. 3, p. 423, doi. 10.1111/j.1750-3639.2008.00141.x
By:
- Claes, An;
- Schuuring, Janneke;
- Boots-Sprenger, Sandra;
- Hendriks-Cornelissen, Sandra;
- Dekkers, Marieke;
- van der Kogel, Albert J.;
- Leenders, William P.;
- Wesseling, Pieter;
- Jeuken, Judith W.
Publication type:
Article
Histopathologic Validation of 3'-Deoxy-3'-18F-Fluorothymidine PET in Squamous Cell Carcinoma of the Oral Cavity.
Published in:
Journal of Nuclear Medicine, 2010, v. 51, n. 5, p. 713, doi. 10.2967/jnumed.109.071910
By:
- Troost, Esther G. C.;
- Bussink, Johan;
- Slootweg, Piet J.;
- Peeters, Wenny J. M.;
- Merkx, Matthias A. W.;
- van der Kogel, Albert J.;
- Oyen, Wim J. G.;
- Kaanders, Johannes H. A. M.
Publication type:
Article
Innovations in Radiotherapy Planning of Head and Neck Cancers: Role of PET.
Published in:
Journal of Nuclear Medicine, 2010, v. 51, n. 1, p. 66, doi. 10.2967/jnumed.108.061499
By:
- Troost, Esther G. C.;
- Schinagl, Dominic A. X.;
- Bussink, Johan;
- Boerman, Otto C.;
- van Der Kogel, Albert J.;
- Oyen, Wim J. G.;
- Kaanders, Johannes H. A. M.
Publication type:
Article
Assessment of the neovascular permeability in glioma xenografts by dynamic T1 MRI with Gadomer-17.
Published in:
Magnetic Resonance in Medicine, 2002, v. 47, n. 2, p. 305, doi. 10.1002/mrm.10072
By:
- Verhoye, Marleen;
- van der Sanden, Boudewijn P.J.;
- Rijken, Paul F.J.W.;
- Peters, Hans P.W.;
- Van der Kogel, Albert J.;
- Pée, Gilke;
- Vanhoutte, Greetje;
- Heerschap, Arend;
- Van der Linden, Annemie
Publication type:
Article
Global HDO uptake in human glioma xenografts is related to the perfused capillary distribution.
Published in:
Magnetic Resonance in Medicine, 1999, v. 42, n. 3, p. 479, doi. 10.1002/(SICI)1522-2594(199909)42:3<479::AID-MRM10>3.0.CO;2-H
By:
- van der Sanden, Boudewijn P.J.;
- 't Zandt, Henricus J.A. in;
- Hoofd, Louis;
- de Graaf, Robin A.;
- Nicolay, Klaas;
- Rijken, Paul F.J.W.;
- van der Kogel, Albert J.;
- Heerschap, Arend
Publication type:
Article
Effect of carbogen breathing on the physiological profile of human glioma xenografts.
Published in:
Magnetic Resonance in Medicine, 1999, v. 42, n. 3, p. 490, doi. 10.1002/(SICI)1522-2594(199909)42:3<490::AID-MRM11>3.0.CO;2-H
By:
- van der Sanden, Boudewijn P.J.;
- Heerschap, Arend;
- Hoofd, Louis;
- Simonetti, Arjan W.;
- Nicolay, Klaas;
- van der Toorn, Annette;
- Colier, Willy N.J.M.;
- van der Kogel, Albert J.
Publication type:
Article
Solid tumors 'melt' from the inside after successful CD8 T cell attack.
Published in:
European Journal of Immunology, 2006, v. 36, n. 2, p. 468, doi. 10.1002/eji.200526175
By:
- Blohm, Ulrike;
- Potthoff, Dan;
- van der Kogel, Albert J.;
- Pircher, Hanspeter
Publication type:
Article
Molecular aspects of tumour hypoxia
Published in:
Molecular Oncology, 2008, v. 2, n. 1, p. 41, doi. 10.1016/j.molonc.2008.03.006
By:
- Rademakers, Saskia E.;
- Span, Paul N.;
- Kaanders, Johannes H.A.M.;
- Sweep, Fred C.G.J.;
- van der Kogel, Albert J.;
- Bussink, Johan
Publication type:
Article
18F-FLT PET Does Not Discriminate Between Reactive and Metastatic Lymph Nodes in Primary Head and Neck Cancer Patients.
Published in:
Journal of Nuclear Medicine, 2007, v. 48, n. 5, p. 726, doi. 10.2967/jnumed.106.037473
By:
- Troost, Esther G. C.;
- Vogel, Wouter V.;
- Merkx, Matthias A.W.;
- Slootweg, Piet J.;
- Marres, Henri A. M.;
- Peeters, Wenny J. M.;
- Bussink, Johan;
- van der Kogel, Albert J.;
- Oyen, Wim J. G.;
- Kaanders, Johannes H. A. M.
Publication type:
Article
Systematic analysis of 18 F-FDG PET and metabolism, proliferation and hypoxia markers for classification of head and neck tumors.
Published in:
BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-130
By:
- Hoeben, Bianca A. W.;
- Starmans, Maud H. W.;
- Leijenaar, Ralph T. H.;
- Dubois, Ludwig J.;
- van der Kogel, Albert J.;
- Kaanders, Johannes H. A. M.;
- Boutros, Paul C.;
- Lambin, Philippe;
- Bussink, Johan
Publication type:
Article
Systematic analysis of 18F-FDG PET and metabolism, proliferation and hypoxia markers for classification of head and neck tumors.
Published in:
2014
By:
- Hoeben, Bianca Aw;
- Starmans, Maud Hw;
- Leijenaar, Ralph Th;
- Dubois, Ludwig J;
- van der Kogel, Albert J;
- Kaanders, Johannes Ham;
- Boutros, Paul C;
- Lambin, Philippe;
- Bussink, Johan;
- Hoeben, Bianca A W;
- Starmans, Maud H W;
- Leijenaar, Ralph T H;
- Kaanders, Johannes H A M
Publication type:
journal article
Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck.
Published in:
BMC Cancer, 2012, v. 12, n. 1, p. 463, doi. 10.1186/1471-2407-12-463
By:
- Stegeman, Hanneke;
- Kaanders, Johannes H.;
- Wheeler, Deric L.;
- van der Kogel, Albert J.;
- Verhejien, Marieke M.;
- Waaijer, Stijn J.;
- Iida, Mari;
- Gr‚nman, Reidar;
- Span, Paul N.;
- Bussink, Johan
Publication type:
Article
Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4.
Published in:
2011
By:
- Rademakers, Saskia E;
- Lok, Jasper;
- van der Kogel, Albert J;
- Bussink, Johan;
- Kaanders, Johannes Ham;
- Kaanders, Johannes H A M
Publication type:
journal article
Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF- 1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4.
Published in:
BMC Cancer, 2011, v. 11, n. 1, p. 167, doi. 10.1186/1471-2407-11-167
By:
- Rademakers, Saskia E.;
- Lok, Jasper;
- van der Kogel, Albert J.;
- Bussink, Johan;
- Kaanders, Johannes H. A. M.
Publication type:
Article

Found: 26

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

Clinical Outcome and Tumour Microenvironmental Effects of Accelerated Radiotherapy with Carbogen and Nicotinamide.

Tumor microenvironment in head and neck squamous cell carcinomas: Predictive value and clinical relevance of hypoxic markers. A review.

Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines.

(64)Cu-ATSM and (18)FDG PET uptake and (64)Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry.

Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer.

Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry.

Method for quantitative mapping of dynamic MRI contrast agent uptake in human tumors.

Transcriptional response to hypoxia in human tumors.

A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis.

Correlation of [<sup>18</sup>F]FMISO autoradiography and pimonodazole immunohistochemistry in human head and neck carcinoma xenografts.

Aerobic glycolysis in cancers: Implications for the usability of oxygen-responsive genes and fluorodeoxyglucose-PET as markers of tissue hypoxia.

Phenotypic and Genotypic Characterization of Orthotopic Human Glioma Models and Its Relevance for the Study of Anti-glioma Therapy.

Histopathologic Validation of 3'-Deoxy-3'-<sup>18</sup>F-Fluorothymidine PET in Squamous Cell Carcinoma of the Oral Cavity.

Innovations in Radiotherapy Planning of Head and Neck Cancers: Role of PET.

Assessment of the neovascular permeability in glioma xenografts by dynamic T<sub>1</sub> MRI with Gadomer-17.

Global HDO uptake in human glioma xenografts is related to the perfused capillary distribution.

Effect of carbogen breathing on the physiological profile of human glioma xenografts.

Solid tumors 'melt' from the inside after successful CD8 T cell attack.

Molecular aspects of tumour hypoxia

<sup>18</sup>F-FLT PET Does Not Discriminate Between Reactive and Metastatic Lymph Nodes in Primary Head and Neck Cancer Patients.

Systematic analysis of <sup>18</sup> F-FDG PET and metabolism, proliferation and hypoxia markers for classification of head and neck tumors.

Systematic analysis of 18F-FDG PET and metabolism, proliferation and hypoxia markers for classification of head and neck tumors.

Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck.

Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4.

Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF- 1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4.