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Comment on: Effectiveness and safety of an institutional aminoglycoside-based regimen as empirical treatment of patients with pyelonephritis.
Published in:
2020
By:
- Spriet, Isabel;
- Hest, Reinier M van;
- Peetermans, Willy E;
- Debaveye, Yves;
- van Hest, Reinier M
Publication type:
Letter
Pharmacokinetics and pharmacodynamic target attainment of ceftriaxone in adult severely ill sub-Saharan African patients: a population pharmacokinetic modelling study.
Published in:
2018
By:
- Bos, Jeannet C;
- Prins, Jan M;
- Mistício, Mabor C;
- Nunguiane, Ginto;
- Lang, Cláudia N;
- Beirão, José C;
- Mathôt, Ron A A;
- Hest, Reinier M van;
- van Hest, Reinier M
Publication type:
journal article
Predicting Beta-Lactam Target Non-Attainment in ICU Patients at Treatment Initiation: Development and External Validation of Three Novel (Machine Learning) Models.
Published in:
Antibiotics (2079-6382), 2023, v. 12, n. 12, p. 1674, doi. 10.3390/antibiotics12121674
By:
- Wieringa, André;
- Ewoldt, Tim M. J.;
- Gangapersad, Ravish N.;
- Gijsen, Matthias;
- Parolya, Nestor;
- Kats, Chantal J. A. R.;
- Spriet, Isabel;
- Endeman, Henrik;
- Haringman, Jasper J.;
- van Hest, Reinier M.;
- Koch, Birgit C. P.;
- Abdulla, Alan
Publication type:
Article
Pharmacokinetic/Pharmacodynamic Target Attainment of Ceftazidime in Adult Patients on General Wards with Different Degrees of Renal Function: A Prospective Observational Bicenter Cohort Study.
Published in:
Antibiotics (2079-6382), 2023, v. 12, n. 3, p. 469, doi. 10.3390/antibiotics12030469
By:
- Zieck, Saskia E.;
- de Vroom, Suzanne L.;
- Mulder, Frouke Ph.;
- van Twillert, Gitte;
- Mathôt, Ron A. A.;
- Geerlings, Suzanne E.;
- van Hest, Reinier M.
Publication type:
Article
Population Pharmacokinetics and Probability of Target Attainment of Different Dosing Regimens of Ceftazidime in Critically Ill Patients with a Proven or Suspected Pseudomonas aeruginosa Infection.
Published in:
Antibiotics (2079-6382), 2021, v. 10, n. 6, p. 612, doi. 10.3390/antibiotics10060612
By:
- Werumeus Buning, Annabel;
- Hodiamont, Caspar J.;
- Lechner, Natalia M.;
- Schokkin, Margriet;
- Elbers, Paul W. G.;
- Juffermans, Nicole P.;
- Mathôt, Ron A. A.;
- de Jong, Menno D.;
- van Hest, Reinier M.
Publication type:
Article
Correction to: Optimizing Predictive Performance of Bayesian Forecasting for Vancomycin Concentration in Intensive Care Patients.
Published in:
2020
By:
- Guo, Tingjie;
- van Hest, Reinier M.;
- Zwep, Laura B.;
- Roggeveen, Luca F.;
- Fleuren, Lucas M.;
- Bosman, Rob J.;
- van der Voort, Peter H. J.;
- Girbes, Armand R. J.;
- Mathot, Ron A. A.;
- Elbers, Paul W. G.;
- van Hasselt, Johan G. C.
Publication type:
Correction Notice
Optimizing Predictive Performance of Bayesian Forecasting for Vancomycin Concentration in Intensive Care Patients.
Published in:
Pharmaceutical Research, 2020, v. 37, n. 9, p. N.PAG, doi. 10.1007/s11095-020-02908-7
By:
- Guo, Tingjie;
- van Hest, Reinier M.;
- Zwep, Laura B.;
- Roggeveen, Luca F.;
- Fleuren, Lucas M.;
- Bosman, Rob J.;
- van der Voort, Peter H. J.;
- Girbes, Armand R. J.;
- Mathot, Ron A. A.;
- Elbers, Paul W. G.;
- van Hasselt, Johan G. C.
Publication type:
Article
Identifying excessive length of antibiotic treatment duration for hospital-acquired infections: a semi-automated approach to support antimicrobial stewardship.
Published in:
Antimicrobial Resistance & Infection Control, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s13756-024-01406-4
By:
- Kuijpers, Suzanne M.E.;
- van Haeringen, Koen J.;
- Groot, Thomas;
- Sigaloff, Kim C.E.;
- van Hest, Reinier M.;
- Prins, Jan M.;
- Schade, Rogier P.
Publication type:
Article
Population pharmacokinetics of vancomycin in term neonates with perinatal asphyxia treated with therapeutic hypothermia.
Published in:
British Journal of Clinical Pharmacology, 2024, v. 90, n. 6, p. 1418, doi. 10.1111/bcp.16026
By:
- van der Veer, Marlotte A. A.;
- de Haan, Timo R.;
- Franken, Linda G. W.;
- van Hest, Reinier M.;
- Groenendaal, Floris;
- Dijk, Peter H.;
- de Boode, Willem P.;
- Simons, Sinno;
- Dijkman, Koen P.;
- van Straaten, Henrica L. M.;
- Rijken, Monique;
- Cools, Filip;
- Nuytemans, Debbie H. G. M.;
- van Kaam, Anton H.;
- Bijleveld, Yuma A.;
- Mathôt, Ron A. A.
Publication type:
Article
Population pharmacokinetic/pharmacodynamic target attainment of ceftriaxone 2 g once daily in non‐critically ill hospitalized adult patients during the acute phase of infection.
Published in:
British Journal of Clinical Pharmacology, 2023, v. 89, n. 11, p. 3262, doi. 10.1111/bcp.15819
By:
- van den Broek, Annemieke K.;
- van Schip, Anne;
- Visser, Caroline E.;
- Bos, Jeannet C.;
- Prins, Jan M.;
- van Hest, Reinier M.
Publication type:
Article
Nonlinear Mixed Effects Modeling of the Diurnal Blood Pressure Profile in a Multiracial Population.
Published in:
American Journal of Hypertension, 2013, v. 26, n. 9, p. 1103, doi. 10.1093/ajh/hpt088
By:
- van Rijn-Bikker, Petra C.;
- Snelder, Nelleke;
- Ackaert, Oliver;
- van Hest, Reinier M.;
- Ploeger, Bart A.;
- van Montfrans, Gert A.;
- Koopmans, Richard P.;
- Mathôt, Ron A.
Publication type:
Article
Right dose, right now: bedside, real-time, data-driven, and personalised antibiotic dosing in critically ill patients with sepsis or septic shock-a two-centre randomised clinical trial.
Published in:
2022
By:
- Roggeveen, Luca F.;
- Guo, Tingjie;
- Fleuren, Lucas M.;
- Driessen, Ronald;
- Thoral, Patrick;
- van Hest, Reinier M.;
- Mathot, Ron A. A.;
- Swart, Eleonora L.;
- de Grooth, Harm-Jan;
- van den Bogaard, Bas;
- Girbes, Armand R. J.;
- Bosman, Rob J.;
- Elbers, Paul W. G.
Publication type:
journal article
Pharmacokinetics and Pharmacodynamic Target Attainment of Benzylpenicillin in an Adult Severely Ill Sub-Saharan African Patient Population.
Published in:
Clinical Infectious Diseases, 2018, v. 66, n. 8, p. 1261, doi. 10.1093/cid/cix961
By:
- Bos, Jeannet C;
- Hest, Reinier M van;
- Mistício, Mabor C;
- Nunguiane, Ginto;
- Lang, Cláudia N;
- Beirão, José C;
- Mathôt, Ron A A;
- Prins, Jan M
Publication type:
Article
Monitoring, documenting and reporting the quality of antibiotic use in the Netherlands: a pilot study to establish a national antimicrobial stewardship registry.
Published in:
2017
By:
- Berrevoets, Marvin A. H.;
- ten Oever, Jaap;
- Sprong, Tom;
- van Hest, Reinier M.;
- Groothuis, Ingeborg;
- van Heijl, Inger;
- Schouten, Jeroen A.;
- Hulscher, Marlies E.;
- Kullberg, Bart-Jan;
- Berrevoets, Marvin Ah
Publication type:
journal article
Antimicrobial prophylaxis outside the operating theatre, an audit in a university hospital.
Published in:
2017
By:
- Deelen, Jan W. T.;
- Visser, Caroline E.;
- Prins, Jan M.;
- van Hest, Reinier M.
Publication type:
journal article
Time-dependent clearance of mycophenolic acid in renal transplant recipients.
Published in:
British Journal of Clinical Pharmacology, 2007, v. 63, n. 6, p. 741, doi. 10.1111/j.1365-2125.2006.02841.x
By:
- van Hest, Reinier M.;
- van Gelder, Teun;
- Bouw, René;
- Goggin, Timothy;
- Gordon, Robert;
- Mamelok, Richard D.;
- Mathot, Ron A.
Publication type:
Article
Pharmacokinetic Modelling of the Plasma Protein Binding of Mycophenolic Acid in Renal Transplant Recipients.
Published in:
Clinical Pharmacokinetics, 2009, v. 48, n. 7, p. 463, doi. 10.2165/11312600-000000000-00000
By:
- van Hest, Reinier M.;
- van Gelder, Teun;
- Vulto, Arnold G.;
- Shaw, Leslie M.;
- Mathot, Ron A. A.
Publication type:
Article
Population pharmacokinetics of mycophenolic acid : a comparison between enteric-coated mycophenolate sodium and mycophenolate mofetil in renal transplant recipients.
Published in:
2008
By:
- de Winter BC;
- van Gelder T;
- Glander P;
- Cattaneo D;
- Tedesco-Silva H;
- Neumann I;
- Hilbrands L;
- van Hest RM;
- Pescovitz MD;
- Budde K;
- Mathot RA;
- de Winter, Brenda C M;
- van Gelder, Teun;
- Glander, Petra;
- Cattaneo, Dario;
- Tedesco-Silva, Helio;
- Neumann, Irmgard;
- Hilbrands, Luuk;
- van Hest, Reinier M;
- Pescovitz, Mark D
Publication type:
journal article
Population Pharmacokinetics of Mycophenolic Acid.
Published in:
Clinical Pharmacokinetics, 2008, v. 47, n. 12, p. 827, doi. 10.2165/0003088-200847120-00007
By:
- de Winter, Brenda C. M.;
- van Gelder, Teun;
- Glander, Petra;
- Cattaneo, Dario;
- Tedesco-Selva, Helio;
- Neumann, Irmgard;
- Hilhrands, Luuk;
- van Hest, Reinier M.;
- Pescovitz, Mark D.;
- Budde, Klemens;
- Mathot, Ron A. A.
Publication type:
Article
Population pharmacokinetics of mycophenolic acid in renal transplant recipients.
Published in:
2005
By:
- van Hest, Reinier M.;
- van Gelder, Teun;
- Vulto, Arnold G.;
- Mathot, Ron A. A.
Publication type:
journal article
Development of Antibiotic Resistance during Simulated Treatment of Pseudomonas aeruginosa in Chemostats.
Published in:
PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149310
By:
- Feng, Yanfang;
- Hodiamont, Caspar J.;
- van Hest, Reinier M.;
- Brul, Stanley;
- Schultsz, Constance;
- ter Kuile, Benno H.
Publication type:
Article
Clinical Pharmacokinetics of Gentamicin in Various Patient Populations and Consequences for Optimal Dosing for Gram-Negative Infections: An Updated Review.
Published in:
2022
By:
- Hodiamont, Caspar J.;
- van den Broek, Annemieke K.;
- de Vroom, Suzanne L.;
- Prins, Jan M.;
- Mathôt, Ron A. A.;
- van Hest, Reinier M.
Publication type:
journal article
Pooled Population Pharmacokinetic Analysis for Exploring Ciprofloxacin Pharmacokinetic Variability in Intensive Care Patients.
Published in:
Clinical Pharmacokinetics, 2022, v. 61, n. 6, p. 869, doi. 10.1007/s40262-022-01114-5
By:
- Guo, Tingjie;
- Abdulla, Alan;
- Koch, Birgit C. P.;
- van Hasselt, Johan G. C.;
- Endeman, Henrik;
- Schouten, Jeroen A.;
- Elbers, Paul W. G.;
- Brüggemann, Roger J. M.;
- van Hest, Reinier M.;
- the Dutch Antibiotic PK/PD Collaborators;
- Roggeveen, Luca F;
- Fleuren, Lucas M.;
- Hunfeld, Nicole G. M.;
- Ewoldt, Tim M. J.;
- Muller, Anouk E.;
- Dijkstra, Annemieke;
- de Lange, Dylan W.;
- Gieling, Emilie;
- Pickkers, Peter;
- ten Oever, Jaap
Publication type:
Article
Population Pharmacokinetics of Clotting Factor Concentrates and Desmopressin in Hemophilia.
Published in:
Clinical Pharmacokinetics, 2021, v. 60, n. 1, p. 1, doi. 10.1007/s40262-020-00936-5
By:
- Preijers, Tim;
- Schütte, Lisette M.;
- Kruip, Marieke J. H. A.;
- Cnossen, Marjon H.;
- Leebeek, Frank W. G.;
- van Hest, Reinier M.;
- Mathôt, Ron A. A.
Publication type:
Article
Pooled Population Pharmacokinetic Analysis and Dose Recommendations for Ciprofloxacin in Intensive Care Unit Patients with Obesity.
Published in:
Journal of Clinical Pharmacology, 2024, v. 64, n. 9, p. 1165, doi. 10.1002/jcph.2450
By:
- van Rhee, Koen P.;
- Brüggemann, Roger J.M.;
- Roberts, Jason A.;
- Sjövall, Fredrik;
- van Hest, Reinier M.;
- Elbers, Paul W.G.;
- Abdulla, Alan;
- van der Linden, Paul D.;
- Knibbe, Catherijne A.J.
Publication type:
Article
Systematic review: the bioavailability of orally administered antibiotics during the initial phase of a systemic infection in non-ICU patients.
Published in:
2021
By:
- van den Broek, Annemieke K.;
- Prins, Jan M.;
- Visser, Caroline E.;
- van Hest, Reinier M.
Publication type:
journal article
Population-specific limited sampling strategies for therapeutic drug monitoring of mycophenolic acid.
Published in:
Journal of Postgraduate Medicine, 2006, v. 52, n. 4, p. 244
By:
- Van Hest, Reinier M.
Publication type:
Article
Detecting inappropriate total duration of antimicrobial therapy using semi-automated surveillance.
Published in:
Antimicrobial Resistance & Infection Control, 2022, v. 11, n. 1, p. 1, doi. 10.1186/s13756-022-01147-2
By:
- van den Broek, Annemieke K.;
- de la Court, Jara R.;
- Groot, Thomas;
- van Hest, Reinier M.;
- Visser, Caroline E.;
- Sigaloff, Kim C. E.;
- Schade, Rogier P.;
- Prins, Jan M.
Publication type:
Article
Peri‐operative desmopressin combined with pharmacokinetic‐guided factor VIII concentrate in non‐severe haemophilia A patients.
Published in:
Haemophilia, 2024, v. 30, n. 2, p. 355, doi. 10.1111/hae.14946
By:
- Romano, Lorenzo G. R.;
- Schütte, Lisette M.;
- van Hest, Reinier M.;
- Meijer, Karina;
- Laros‐van Gorkom, Britta A. P.;
- Nieuwenhuizen, Laurens;
- Eikenboom, Jeroen;
- Heubel‐Moenen, Floor C. J. I.;
- Uitslager, Nanda;
- Coppens, Michiel;
- Fijnvandraat, Karin;
- Driessens, Mariëtte H. E.;
- Polinder, Suzanne;
- Cnossen, Marjon H.;
- Leebeek, Frank W. G.;
- Mathôt, Ron A. A.;
- Kruip, Marieke J. H. A.
Publication type:
Article
Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study.
Published in:
BMC Research Notes, 2017, v. 10, p. 1, doi. 10.1186/s13104-017-3016-8
By:
- Bos, Jeannet C.;
- Mistício, Mabor C.;
- Nunguiane, Ginto;
- Mathôt, Ron A. A.;
- van Hest, Reinier M.;
- Prins, Jan M.
Publication type:
Article
A cluster randomized trial for the implementation of an antibiotic checklist based on validated quality indicators: the AB-checklist.
Published in:
BMC Infectious Diseases, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12879-015-0867-2
By:
- van Daalen, Frederike V.;
- Prins, Jan M.;
- Opmeer, Brent C.;
- Boermeester, Marja A.;
- Visser, Caroline E.;
- van Hest, Reinier M.;
- Hulscher, Marlies E. J. L.;
- Geerlings, Suzanne E.
Publication type:
Article
Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations.
Published in:
2020
By:
- Jager, Nynke G L;
- van Hest, Reinier M;
- Xie, Jiao;
- Wong, Gloria;
- Ulldemolins, Marta;
- Brüggemann, Roger J M;
- Lipman, Jeffrey;
- Roberts, Jason A
Publication type:
journal article
The appropriateness of antimicrobial use in the outpatient clinics of three hospitals in the Netherlands.
Published in:
Antimicrobial Resistance & Infection Control, 2020, v. 9, n. 1, p. 1, doi. 10.1186/s13756-020-0689-x
By:
- van den Broek, Annemieke K.;
- van Hest, Reinier M.;
- Lettinga, Kamilla D.;
- Jimmink, Afra;
- Lauw, Fanny N.;
- Visser, Caroline E.;
- Prins, Jan M.
Publication type:
Article

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