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Dose-finding designs for cumulative toxicities using multiple constraints.
- Published in:
- 2019
- By:
- Publication type:
- journal article
The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia.
- Published in:
- Pharmaceutics, 2021, v. 13, n. 5, p. 601, doi. 10.3390/pharmaceutics13050601
- By:
- Publication type:
- Article
Does the low prevalence affect the sample size of interventional clinical trials of rare diseases? An analysis of data from the aggregate analysis of clinicaltrials.gov.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Bayesian framework for multi-source data integration-Application to human extrapolation from preclinical studies.
- Published in:
- Statistical Methods in Medical Research, 2024, v. 33, n. 4, p. 574, doi. 10.1177/09622802241231493
- By:
- Publication type:
- Article
Using dichotomized survival data to construct a prior distribution for a Bayesian seamless Phase II/III clinical trial.
- Published in:
- Statistical Methods in Medical Research, 2023, v. 32, n. 5, p. 963, doi. 10.1177/09622802231160554
- By:
- Publication type:
- Article
An adaptive power prior for sequential clinical trials - Application to bridging studies.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Integration of elicited expert information via a power prior in Bayesian variable selection: Application to colon cancer data.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Bayesian treatment comparison using parametric mixture priors computed from elicited histograms.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Unified approach for extrapolation and bridging of adult information in early-phase dose-finding paediatric studies.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Phase I/II dose-finding design for molecularly targeted agent: Plateau determination using adaptive randomization.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Decision-theoretic designs for small trials and pilot studies: A review.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Discussion on "Bayesian meta-analysis of penetrance for cancer risk" by Thanthirige Lakshika M. Ruberu, Danielle Braun, Giovanni Parmigiani, and Swati Biswas.
- Published in:
- Biometrics, 2024, v. 80, n. 2, p. 1, doi. 10.1093/biomtc/ujae043
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- Publication type:
- Article
Bayesian dose regimen assessment in early phase oncology incorporating pharmacokinetics and pharmacodynamics.
- Published in:
- Biometrics, 2022, v. 78, n. 1, p. 300, doi. 10.1111/biom.13433
- By:
- Publication type:
- Article
Recent advances in methodology for clinical trials in small populations: the InSPiRe project.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Estimating Similarity of Dose–Response Relationships in Phase I Clinical Trials—Case Study in Bridging Data Package.
- Published in:
- International Journal of Environmental Research & Public Health, 2021, v. 18, n. 4, p. 1639, doi. 10.3390/ijerph18041639
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- Publication type:
- Article
Determination of the optimal sample size for a clinical trial accounting for the population size.
- Published in:
- Biometrical Journal, 2017, v. 59, n. 4, p. 609, doi. 10.1002/bimj.201500228
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- Publication type:
- Article
Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations.
- Published in:
- Biometrical Journal, 2017, v. 59, n. 4, p. 804, doi. 10.1002/bimj.201600084
- By:
- Publication type:
- Article
A Bayesian non-inferiority approach using experts' margin elicitation - application to the monitoring of safety events.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Intracerebral administration of CpG oligonucleotide for patients with recurrent glioblastoma: a phase II study.
- Published in:
- Neuro-Oncology, 2010, v. 12, n. 4, p. 401, doi. 10.1093/neuonc/nop047
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- Publication type:
- Article
Phase 1 trial of a CpG oligodeoxynucleotide for patients with recurrent glioblastoma.
- Published in:
- Neuro-Oncology, 2006, v. 8, n. 1, p. 60, doi. 10.1215/S1522851705000475
- By:
- Publication type:
- Article
Bayesian sample size determination for phase IIA clinical trials using historical data and semi‐parametric prior's elicitation.
- Published in:
- Pharmaceutical Statistics, 2019, v. 18, n. 2, p. 198, doi. 10.1002/pst.1914
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- Publication type:
- Article
Approaches to sample size calculation for clinical trials in rare diseases.
- Published in:
- Pharmaceutical Statistics, 2018, v. 17, n. 3, p. 214, doi. 10.1002/pst.1848
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- Publication type:
- Article
A Bayesian dose-finding design for drug combination clinical trials based on the logistic model.
- Published in:
- Pharmaceutical Statistics, 2014, v. 13, n. 4, p. 247, doi. 10.1002/pst.1621
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- Publication type:
- Article
An adaptive model switching approach for phase I dose-finding trials.
- Published in:
- Pharmaceutical Statistics, 2013, v. 12, n. 4, p. 225, doi. 10.1002/pst.1578
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- Publication type:
- Article
Planning a Bayesian early-phase phase I/II study for human vaccines in HER2 carcinomas.
- Published in:
- Pharmaceutical Statistics, 2011, v. 10, n. 3, p. 218, doi. 10.1002/pst.450
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- Publication type:
- Article
Identifying the most successful dose (MSD) in dose-finding studies in cancer.
- Published in:
- Pharmaceutical Statistics, 2006, v. 5, n. 3, p. 187, doi. 10.1002/pst.209
- By:
- Publication type:
- Article
A Survey of the Way Pharmacokinetics are Reported in Published Phase I Clinical Trials, with an Emphasis on Oncology.
- Published in:
- Clinical Pharmacokinetics, 2009, v. 48, n. 6, p. 387, doi. 10.2165/00003088-200948060-00004
- By:
- Publication type:
- Article
Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Dose-Finding Study of Omeprazole on Gastric pH in Neonates with Gastro-Esophageal Acid Reflux Using a Bayesian Sequential Approach.
- Published in:
- PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0166207
- By:
- Publication type:
- Article
Evaluation of the Effects of Pasireotide LAR Administration on Lymphocele Prevention after Axillary Node Dissection for Breast Cancer: Results of a Randomized Non-Comparative Phase 2 Study.
- Published in:
- PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0156096
- By:
- Publication type:
- Article
Dose-finding designs using a novel quasi-continuous endpoint for multiple toxicities.
- Published in:
- Statistics in Medicine, 2013, v. 32, n. 16, p. 2728, doi. 10.1002/sim.5737
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- Publication type:
- Article
A Bayesian predictive sample size selection design for single-arm exploratory clinical trials.
- Published in:
- Statistics in Medicine, 2012, v. 31, n. 30, p. 4243, doi. 10.1002/sim.5505
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- Publication type:
- Article
An approach to meta-analysis of dose-finding studies.
- Published in:
- Statistics in Medicine, 2011, v. 30, n. 17, p. 2109, doi. 10.1002/sim.4121
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- Publication type:
- Article
Optimal designs for estimating the most successful dose.
- Published in:
- Statistics in Medicine, 2006, v. 25, n. 24, p. 4311, doi. 10.1002/sim.2685
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- Publication type:
- Article
Evaluation of an algorithm based on peripheral blood hematopoietic progenitor cell and CD34+ cell concentrations to optimize peripheral blood progenitor cell collection by apheresis.
- Published in:
- Transfusion, 2007, v. 47, n. 10, p. 1851, doi. 10.1111/j.1537-2995.2007.01407.x
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- Publication type:
- Article
A dose finding design for seizure reduction in neonates.
- Published in:
- Journal of the Royal Statistical Society: Series C (Applied Statistics), 2019, v. 68, n. 2, p. 427, doi. 10.1111/rssc.12289
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- Publication type:
- Article
Autologous bone marrow transplantation in the treatment of refractory systemic sclerosis: early results from a French multicentre phase I–II study.
- Published in:
- British Journal of Haematology, 2002, v. 119, n. 3, p. 726, doi. 10.1046/j.1365-2141.2002.03895.x
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- Publication type:
- Article
Value of information methods to design a clinical trial in a small population to optimise a health economic utility function.
- Published in:
- 2018
- By:
- Publication type:
- journal article
A straightforward meta‐analysis approach for oncology phase I dose‐finding studies.
- Published in:
- Statistics in Medicine, 2022, v. 41, n. 20, p. 3915, doi. 10.1002/sim.9484
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- Publication type:
- Article
Bayesian modeling of a bivariate toxicity outcome for early phase oncology trials evaluating dose regimens.
- Published in:
- Statistics in Medicine, 2021, v. 40, n. 23, p. 5096, doi. 10.1002/sim.9113
- By:
- Publication type:
- Article
Bayesian variable selection based on clinical relevance weights in small sample studies-Application to colon cancer.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Comments on 'A comparative study of adaptive dose-finding designs for phase I oncology trials of combination therapies'.
- Published in:
- 2016
- By:
- Publication type:
- journal article
An extension of Bayesian predictive sample size selection designs for monitoring efficacy and safety.
- Published in:
- Statistics in Medicine, 2015, v. 34, n. 22, p. 3029, doi. 10.1002/sim.6550
- By:
- Publication type:
- Article
Response to comments on 'Competing designs for drug combination in phase I dose-finding clinical trials' by G. Yin, R. Lin and N. Wages.
- Published in:
- Statistics in Medicine, 2015, v. 34, n. 1, p. 23, doi. 10.1002/sim.6332
- By:
- Publication type:
- Article
Personalized Dynamic Treatment Regimes in Continuous Time: A Bayesian Approach for Optimizing Clinical Decisions with Timing.
- Published in:
- Bayesian Analysis, 2022, v. 17, n. 3, p. 849, doi. 10.1214/21-BA1276
- By:
- Publication type:
- Article
Robust Adaptive Incorporation of Historical Control Data in a Randomized Trial of External Cooling to Treat Septic Shock.
- Published in:
- Bayesian Analysis, 2021, v. 16, n. 3, p. 825, doi. 10.1214/20-BA1229
- By:
- Publication type:
- Article
Re: Dose Escalation Methods in Phase I Cancer Clinical Trials.
- Published in:
- 2009
- By:
- Publication type:
- Letter
Modeling of experts’ divergent prior beliefs for a sequential phase III clinical trial.
- Published in:
- 2013
- By:
- Publication type:
- Journal Article
Modeling of experts’ divergent prior beliefs for a sequential phase III clinical trial.
- Published in:
- Clinical Trials, 2013, v. 10, n. 4, p. 505, doi. 10.1177/1740774513493528
- By:
- Publication type:
- Article