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Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24900-4
By:
- Schützmann, Marie P.;
- Hasecke, Filip;
- Bachmann, Sarah;
- Zielinski, Mara;
- Hänsch, Sebastian;
- Schröder, Gunnar F.;
- Zempel, Hans;
- Hoyer, Wolfgang
Publication type:
Article
Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01765-1
By:
- Cukkemane, Abhishek;
- Becker, Nina;
- Zielinski, Mara;
- Frieg, Benedikt;
- Lakomek, Nils-Alexander;
- Heise, Henrike;
- Schröder, Gunnar F.;
- Willbold, Dieter;
- Weiergräber, Oliver H.
Publication type:
Article
The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.
Published in:
Science Translational Medicine, 2021, v. 13, n. 606, p. 1, doi. 10.1126/scitranslmed.abc6184
By:
- Pagnon de la Vega, María;
- Giedraitis, Vilmantas;
- Michno, Wojciech;
- Kilander, Lena;
- Güner, Gökhan;
- Zielinski, Mara;
- Löwenmark, Malin;
- Brundin, RoseMarie;
- Danfors, Torsten;
- Söderberg, Linda;
- Alafuzoff, Irina;
- Nilsson, Lars N.G.;
- Erlandsson, Anna;
- Willbold, Dieter;
- Müller, Stephan A.;
- Schröder, Gunnar F.;
- Hanrieder, Jörg;
- Lichtenthaler, Stefan F.;
- Lannfelt, Lars;
- Sehlin, Dag
Publication type:
Article

Found: 3

Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting.

Conformational heterogeneity coupled with β-fibril formation of a scaffold protein involved in chronic mental illnesses.

The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.