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A Phase I Trial of the PI3K Inhibitor Buparlisib Combined With Capecitabine in Patients With Metastatic Breast Cancer.
Published in:
2018
By:
- McRee, Autumn J.;
- Marcom, Paul K.;
- Moore, Dominic T.;
- Zamboni, William C.;
- Kornblum, Zachary A.;
- Zhiyuan Hu;
- Phipps, Rachel;
- Anders, Carey K.;
- Reeder-Hayes, Katherine;
- Carey, Lisa A.;
- Weck, Karen E.;
- Perou, Charles M.;
- Dees, E. Claire;
- Hu, Zhiyuan
Publication type:
journal article
Complex Factors and Challenges that Affect the Pharmacology, Safety and Efficacy of Nanocarrier Drug Delivery Systems.
Published in:
Pharmaceutics, 2021, v. 13, n. 1, p. 114, doi. 10.3390/pharmaceutics13010114
By:
- Piscatelli, Joseph A.;
- Ban, Jisun;
- Lucas, Andrew T.;
- Zamboni, William C.
Publication type:
Article
It takes a village to raise awareness of and to address surface contamination of hazardous drugs.
Published in:
Journal of Oncology Pharmacy Practice, 2017, v. 23, n. 7, p. 558, doi. 10.1177/1078155217724650
By:
- Zamboni, William C.;
- Salch, Stephanie A.;
- Cox, Joshua;
- Eckel, Stephen
Publication type:
Article
Development and evaluation of a novel product to remove surface contamination of hazardous drugs.
Published in:
Journal of Oncology Pharmacy Practice, 2017, v. 23, n. 2, p. 103, doi. 10.1177/1078155215621151
By:
- Cox, Joshua;
- Speed, Vonni;
- O’Neal, Sara;
- Hasselwander, Terry;
- Sherwood, Candice;
- Eckel, Stephen F.;
- Zamboni, William C.
Publication type:
Article
First‐in‐human, phase I/IIa study of CRLX301, a nanoparticle drug conjugate containing docetaxel, in patients with advanced or metastatic solid malignancies.
Published in:
Investigational New Drugs, 2021, v. 39, n. 4, p. 1047, doi. 10.1007/s10637-021-01081-x
By:
- Piha-Paul, Sarina A.;
- Thein, Kyaw Z.;
- De Souza, Paul;
- Kefford, Richard;
- Gangadhar, Tara;
- Smith, Christopher;
- Schuster, Shelly;
- Zamboni, William C.;
- Dees, Claire E.;
- Markman, Ben
Publication type:
Article
Nonaqueous Gel for the Transdermal Delivery of a DTPA Penta-ethyl Ester Prodrug.
Published in:
AAPS Journal, 2013, v. 15, n. 2, p. 523, doi. 10.1208/s12248-013-9459-5
By:
- Yong Zhang;
- Sadgrove, Matthew P.;
- Sueda, Katsuhiko;
- Yu-Tsai Yang;
- Pacyniak, Erik K.;
- Kagel, John R.;
- Braun, Brenda A.;
- Zamboni, William C.;
- Mumper, Russell J.;
- Jay, Michael
Publication type:
Article
Minibeam radiation therapy enhanced tumor delivery of PEGylated liposomal doxorubicin in a triple-negative breast cancer mouse model.
Published in:
Therapeutic Advances in Medical Oncology, 2021, p. 1, doi. 10.1177/17588359211053700
By:
- Price, Lauren S.L.;
- Rivera, Judith N.;
- Madden, Andrew J.;
- Herity, Leah B.;
- Piscitelli, Joseph A.;
- Mageau, Savannah;
- Santos, Charlene M.;
- Roques, Jose R.;
- Midkiff, Bentley;
- Feinberg, Nana N.;
- Darr, David;
- Chang, Sha X.;
- Zamboni, William C.
Publication type:
Article
Minibeam radiation therapy enhanced tumor delivery of PEGylated liposomal doxorubicin in a triple-negative breast cancer mouse model.
Published in:
Therapeutic Advances in Medical Oncology, 2021, p. 1, doi. 10.1177/17588359211053700
By:
- Price, Lauren S.L.;
- Rivera, Judith N.;
- Madden, Andrew J.;
- Herity, Leah B.;
- Piscitelli, Joseph A.;
- Mageau, Savannah;
- Santos, Charlene M.;
- Roques, Jose R.;
- Midkiff, Bentley;
- Feinberg, Nana N.;
- Darr, David;
- Chang, Sha X.;
- Zamboni, William C.
Publication type:
Article
Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer
Published in:
PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0061359
By:
- Anders, Carey K.;
- Adamo, Barbara;
- Karginova, Olga;
- Deal, Allison M.;
- Rawal, Sumit;
- Darr, David;
- Schorzman, Allison;
- Santos, Charlene;
- Bash, Ryan;
- Kafri, Tal;
- Carey, Lisa;
- Miller, C. Ryan;
- Perou, Charles M.;
- Sharpless, Norman;
- Zamboni, William C.
Publication type:
Article
Patterns and characteristics associated with surface contamination of hazardous drugs in hospital pharmacies.
Published in:
American Journal of Health-System Pharmacy, 2019, v. 76, n. 9, p. 591, doi. 10.1093/ajhp/zxz033
By:
- Salch, Stephanie A;
- Zamboni, William C;
- Zamboni, Beth A;
- Eckel, Stephen F
Publication type:
Article
Schedule-dependent Efficacy of Camptothecins in Models of Human Cancer<sup>a</sup>.
Published in:
Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 188, doi. 10.1111/j.1749-6632.1996.tb26388.x
By:
- HOUGHTON, PETER J.;
- STEWART, CLINTON F.;
- ZAMBONI, WILLIAM C.;
- THOMPSON, JOYCE;
- LUO, XIALOLONG;
- DANKS, MARY K.;
- HOUGHTON, JANET A.
Publication type:
Article
Relationship between topotecan systemic exposure and tumor response in human neuroblastoma xenografts.
Published in:
1998
By:
- Zamboni, William C.;
- Thompson, Joyce;
- Stewart, Clinton F.;
- Santana, Victor M.;
- Cheshire, Pamela J.;
- Richmond, Lois B.;
- Luo, Xiaolong;
- Poquette, Catherine;
- Houghton, Janet A.;
- Houghton, Peter J.;
- Zamboni, W C;
- Stewart, C F;
- Thompson, J;
- Santana, V M;
- Cheshire, P J;
- Richmond, L B;
- Luo, X;
- Poquette, C;
- Houghton, J A;
- Houghton, P J
Publication type:
journal article
Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors [Corrigendum].
Published in:
International Journal of Nanomedicine, 2019, v. 14, p. 5751, doi. 10.2147/IJN.S207276
By:
- Wu, Huali;
- Infante, Jeffrey R;
- Keedy, Vicki L;
- Jones, Suzanne F;
- Chan, Emily;
- Bendell, Johanna C;
- Lee, Wooin;
- Kirschbrown, Whitney P;
- Zamboni, Beth A;
- Ikeda, Satoshi;
- Kodaira, Hiroshi;
- Rothenberg, Mace L;
- III, Howard A Burris;
- Zamboni, William C
Publication type:
Article
Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors.
Published in:
International Journal of Nanomedicine, 2015, v. 10, p. 1201, doi. 10.2147/IJN.S62911
By:
- Huali Wu;
- Infante, Jeffrey R.;
- Keedy, Vicki L.;
- Jones, Suzanne F.;
- chan, Emily;
- Bendell, Johanna C.;
- lee, Wooin;
- Kirschbrown, Whitney P.;
- Zamboni, Beth A.;
- Ikeda, Satoshi;
- Kodaira, Hiroshi;
- Rothenberg, Mace L.;
- Burris III, Howard A.;
- Zamboni, William C.
Publication type:
Article
2'-(2-bromohexadecanoyl)-paclitaxel conjugate nanoparticles for the treatment of non-small cell lung cancer in an orthotopic xenograft mouse model.
Published in:
International Journal of Nanomedicine, 2014, v. 9, p. 3601, doi. 10.2147/IJN.S66040
By:
- Lei Peng;
- Schorzman, Allison N.;
- Ping Ma;
- Madden, Andrew J.;
- Zamboni, William C.;
- Benhabbour, Soumya Rahima;
- Mumper, Russell J.
Publication type:
Article
Mechanism-based model characterizing bidirectional interaction between PEGylated liposomal CKD-602 (S-CKD602) and monocytes in cancer patients.
Published in:
International Journal of Nanomedicine, 2012, v. 7, p. 5555, doi. 10.2147/IJN.S35751
By:
- Huali Wu;
- Ramanathan, Ramesh K.;
- Zamboni, Beth A.;
- Strychor, Sandra;
- Ramalingam, Suresh;
- Edwards, Robert P.;
- Friedland, David M.;
- Stoller, Ronald G.;
- Belani, Chandra P.;
- Maruca, Lauren J.;
- Yung-Jue Bang;
- Zamboni, William C.
Publication type:
Article
MerTK as a therapeutic target in glioblastomaas a therapeutic target in glioblastoma.
Published in:
Neuro-Oncology, 2018, v. 20, n. 1, p. 92, doi. 10.1093/neuonc/nox111
By:
- Jing Wu;
- Frady, Lauren N.;
- Bash, Ryan E.;
- Cohen, Stephanie M.;
- Schorzman, Allison N.;
- Yu-Ting Su;
- Irvin, David M.;
- Zamboni, William C.;
- Xiaodong Wang;
- Frye, Stephen V.;
- Ewend, Matthew G.;
- Sulman, Erik P.;
- Gilbert, Mark R.;
- Earp, H. Shelton;
- Miller, C. Ryan
Publication type:
Article
Population pharmacokinetics of PEGylated liposomal CPT-11 (IHL-305) in patients with advanced solid tumors.
Published in:
European Journal of Clinical Pharmacology, 2013, v. 69, n. 12, p. 2073, doi. 10.1007/s00228-013-1580-y
By:
- Wu, Huali;
- Infante, Jeffrey R.;
- Keedy, Vicki L.;
- Jones, Suzanne F.;
- Chan, Emily;
- Bendell, Johanna C.;
- Lee, Wooin;
- Zamboni, Beth A.;
- Ikeda, Satoshi;
- Kodaira, Hiroshi;
- Rothenberg, Mace L.;
- Burris III, Howard A.;
- Zamboni, William C.
Publication type:
Article
Mononuclear phagocyte system function and nanoparticle pharmacology in obese and normal weight ovarian and endometrial cancer patients.
Published in:
2019
By:
- Starling, Brittney R.;
- Kumar, Parag;
- Lucas, Andrew T.;
- Barrow, David;
- Farnan, Laura;
- Hendrix, Laura;
- Giovinazzo, Hugh;
- Song, Gina;
- Gehrig, Paola;
- Bensen, Jeannette T.;
- Zamboni, William C.
Publication type:
journal article
Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer.
Published in:
2018
By:
- Byrne, James D.;
- Jajja, Mohammad R. N.;
- O’Neill, Adrian T.;
- Schorzman, Allison N.;
- Keeler, Amanda W.;
- Luft, J. Christopher;
- Zamboni, William C.;
- DeSimone, Joseph M.;
- Yeh, Jen Jen;
- O'Neill, Adrian T
Publication type:
journal article
Tumor, tissue, and plasma pharmacokinetic studies and antitumor response studies of docetaxel in combination with 9-nitrocamptothecin in mice bearing SKOV-3 human ovarian xenografts.
Published in:
Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 3, p. 417, doi. 10.1007/s00280-007-0620-7
By:
- Zamboni, William C.;
- Strychor, Sandra;
- Joseph, Erin;
- Parise, Robert A.;
- Egorin, Merrill J.;
- Eiseman, Julie L
Publication type:
Article
Clinical and pharmacokinetic study evaluating the effect of food on the disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in patients with solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 5, p. 631, doi. 10.1007/s00280-005-0084-6
By:
- Zamboni, William C.;
- Goel, Sanjay;
- Iqbal, Tahir;
- Parise, Robert A.;
- Strychor, Sandra;
- Repinski, Trisha V. W.;
- Egorin, Merrill J.;
- Mani, Sridhar
Publication type:
Article
Phase-I dose escalation and sequencing study of docetaxel and continuous infusion topotecan in patients with advanced malignancies.
Published in:
Cancer Chemotherapy & Pharmacology, 2005, v. 56, n. 2, p. 182, doi. 10.1007/s00280-004-0925-8
By:
- Posey, James;
- Hui Wang;
- Hamilton, JoElle;
- Delgrosso, Alma;
- Ruiwen Zhang;
- Freda, Timothy;
- Zamboni, William C.
Publication type:
Article
Phase I study of weekly (day 1 and 8) docetaxel in combination with capecitabine in patients with advanced solid malignancies.
Published in:
2005
By:
- Ramanathan, Ramesh K.;
- Ramalingam, Sakkaraiappan;
- Egorin, Merrill J.;
- Belani, Chandra P.;
- Potter, Douglas M.;
- Fakih, Marwan;
- Jung, Laura L.;
- Strychor, Sandra;
- Jacobs, Samuel A.;
- Friedland, David M.;
- Shin, Dong M.;
- Chatta, Gurkamal S.;
- Tutchko, Susan;
- Zamboni, William C.
Publication type:
journal article
Pharmacokinetic studies of 9-nitrocamptothecin on intermittent and continuous schedules of administration in patients with solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2004, v. 54, n. 6, p. 487, doi. 10.1007/s00280-004-0835-9
By:
- Jung, Laura L.;
- Ramanathan, Ramesh K.;
- Egorin, Merrill J.;
- Jin, Ruzhi;
- Belani, Chandra P.;
- Potter, Douglas M.;
- Strychor, Sandra;
- Trump, Donald L.;
- Walko, Christine;
- Fakih, Marwan;
- Zamboni, William C.
Publication type:
Article
Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 4, p. 329, doi. 10.1007/s00280-003-0719-4
By:
- Zamboni, William C.;
- Gervais, Anne C.;
- Egorin, Merrill J.;
- Schellens, Jan H. M.;
- Zuhowski, Elleanor G.;
- Pluim, Dick;
- Joseph, Erin;
- Hamburger, Deborah R.;
- Working, Peter K.;
- Colbern, Gail;
- Tonda, Margaret E.;
- Potter, Douglas M.;
- Eiseman, Julie L.
Publication type:
Article
Phase I study of docetaxel and topotecan in patients with solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2000, v. 46, n. 6, p. 442, doi. 10.1007/s002800000180
By:
- Tkaczuk, Katherine H.;
- Zamboni, William C.;
- Tait, Nancy S.;
- Meisenberg, Barry R.;
- Doyle, L. Austin;
- Edelman, Martin J.;
- Hausner, Petr F.;
- Egorin, Merrill J.;
- Van Echo, David A.
Publication type:
Article
Importance and Considerations of Antibody Engineering in Antibody-Drug Conjugates Development from a Clinical Pharmacologist's Perspective.
Published in:
Antibodies (2073-4468), 2021, v. 10, n. 3, p. 30, doi. 10.3390/antib10030030
By:
- Lucas, Andrew T.;
- Moody, Amber;
- Schorzman, Allison N.;
- Zamboni, William C.
Publication type:
Article
Pharmacologic Considerations in the Disposition of Antibodies and Antibody-Drug Conjugates in Preclinical Models and in Patients.
Published in:
Antibodies (2073-4468), 2019, v. 8, n. 1, p. 3, doi. 10.3390/antib8010003
By:
- Lucas, Andrew T.;
- Robinson, Ryan;
- Schorzman, Allison N.;
- Piscitelli, Joseph A.;
- Razo, Juan F.;
- Zamboni, William C.
Publication type:
Article
Factors Affecting the Pharmacology of Antibody-Drug Conjugates.
Published in:
Antibodies (2073-4468), 2018, v. 7, n. 1, p. 10, doi. 10.3390/antib7010010
By:
- Lucas, Andrew T.;
- Price, Lauren S. L.;
- Schorzman, Allison N.;
- Storrie, Mallory;
- Piscitelli, Joseph A.;
- Razo, Juan;
- Zamboni, William C.
Publication type:
Article
Population Pharmacokinetics of Pegylated Liposomal CKD-602 (S-CKD602) in Patients With Advanced Malignancies.
Published in:
Journal of Clinical Pharmacology, 2012, v. 52, n. 2, p. 180, doi. 10.1177/0091270010394851
By:
- Wu, Huali;
- Ramanathan, Ramesh K.;
- Zamboni, Beth A.;
- Strychor, Sandra;
- Ramalingam, Suresh;
- Edwards, Robert P.;
- Friedland, David M.;
- Stoller, Ronald G.;
- Belani, Chandra P.;
- Maruca, Lauren J.;
- Bang, Yung-Jue;
- Zamboni, William C.
Publication type:
Article
Challenges in preclinical to clinical translation for anticancer carrier-mediated agents.
Published in:
WIREs: Nanomedicine & Nanobiotechnology, 2016, v. 8, n. 5, p. 642, doi. 10.1002/wnan.1394
By:
- Lucas, Andrew T.;
- Madden, Andrew J.;
- Zamboni, William C.
Publication type:
Article
Effect of Obesity on the Pharmacokinetics and Pharmacodynamics of Anticancer Agents.
Published in:
Journal of Clinical Pharmacology, 2023, v. 63, p. S85, doi. 10.1002/jcph.2326
By:
- Zamboni, William C.;
- Charlab, Rosane;
- Burckart, Gilbert J.;
- Stewart, Clinton F.
Publication type:
Article
Genetically Engineered Cancer Models, But Not Xenografts, Faithfully Predict Anticancer Drug Exposure in Melanoma Tumors.
Published in:
Oncologist, 2012, v. 17, n. 10, p. 1303, doi. 10.1634/theoncologist.2012-0274
By:
- Combest, Austin J.;
- Roberts, Patrick J.;
- Dillon, Patrick M.;
- Sandison, Katie;
- Hanna, Suzan K.;
- Ross, Charlene;
- Habibi, Sohrab;
- Zamboni, Beth;
- Müller, Markus;
- Brunner, Martin;
- Sharpless, Norman E.;
- Zamboni, William C.
Publication type:
Article
Concept and Clinical Evaluation of Carrier-Mediated Anticancer Agents.
Published in:
Oncologist, 2008, v. 13, n. 3, p. 248, doi. 10.1634/theoncologist.2007-0180
By:
- Zamboni, William C.
Publication type:
Article
From Immunotoxicity to Nanotherapy: The Effects of Nanomaterials on the Immune System.
Published in:
Toxicological Sciences, 2014, v. 138, n. 2, p. 249, doi. 10.1093/toxsci/kfu005
By:
- Smith, Matthew J.;
- Brown, Jared M.;
- Zamboni, William C.;
- Walker, Nigel J.
Publication type:
Article
Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy.
Published in:
JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 6, p. 476, doi. 10.1093/jnci/djs002
By:
- Roberts, Patrick J.;
- Bisi, John E.;
- Strum, Jay C.;
- Combest, Austin J.;
- Darr, David B.;
- Usary, Jerry E.;
- Zamboni, William C.;
- Wong, Kwok-Kin;
- Perou, Charles M.;
- Sharpless, Norman E.
Publication type:
Article
Pharmacokinetics and toxicity of subcutaneous administration of carboplatin in poloxamer 407 in a rodent model pilot study.
Published in:
PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0186018
By:
- Risselada, Marije;
- Linder, Keith E.;
- Griffith, Emily;
- Roberts, Brittney V.;
- Davidson, Gigi;
- Zamboni, William C.;
- Messenger, Kristen M.
Publication type:
Article

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