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Opportunistic Infections, Mortality Risk, and Prevention Strategies in Patients With Vacuoles, E1 Enzyme, X-Linked, Autoinflammatory, Somatic (VEXAS) Syndrome.
Published in:
Open Forum Infectious Diseases, 2024, v. 11, n. 7, p. 1, doi. 10.1093/ofid/ofae405
By:
- Czech, Mary;
- Cuellar-Rodriguez, Jennifer;
- Patel, Bhavisha A;
- Groarke, Emma M;
- Cowen, Edward W;
- Turturice, Benjamin;
- Beck, David B;
- Wilson, Lorena;
- Goodspeed, Wendy;
- Darden, Ivana;
- Young, Neal S;
- Hickstein, Dennis;
- Ombrello, Amanda;
- Hoffman, Patrycjia;
- Arikan, Evsen Apaydin;
- Sinaii, Ninet;
- Hathaway, Londa;
- Castelo-Soccio, Leslie;
- Fike, Alice;
- Kastner, Daniel B
Publication type:
Article
Skin Manifestations of VEXAS Syndrome and Associated Genotypes.
Published in:
JAMA Dermatology, 2024, v. 160, n. 8, p. 822, doi. 10.1001/jamadermatol.2024.1657
By:
- Tan, Isabella J.;
- Ferrada, Marcela A.;
- Ahmad, Serene;
- Fike, Alice;
- Quinn, Kaitlin A.;
- Groarke, Emma M.;
- Beck, David B.;
- Allbritton, Jill;
- Castelo-Soccio, Leslie;
- Young, Neal S.;
- Patel, Bhavisha A.;
- Grayson, Peter C.;
- Cowen, Edward W.
Publication type:
Article
Aplastic Anemia and Immunosuppression.
Published in:
JAMA: Journal of the American Medical Association, 2003, v. 290, n. 2, p. 193, doi. 10.1001/jama.290.2.193-b
By:
- Nagy, Jr, Stephen M.;
- Fisher, John J.;
- Young, Neal S.;
- Rosenfeld, Stephen
Publication type:
Article
Antithymocyte Globulin and Cyclosporine for Severe Aplastic Anemia: Association Between Hematologic Response and Long-term Outcome.
Published in:
JAMA: Journal of the American Medical Association, 2003, v. 289, n. 9, p. 1130, doi. 10.1001/jama.289.9.1130
By:
- Rosenfeld, Stephen;
- Follmann, Dean;
- Nunez, Olga;
- Young, Neal S.
Publication type:
Article
Acquired aplastic anemia.
Published in:
1999
By:
- Young, Neal S.;
- Young, N S
Publication type:
journal article
The relationship of aplastic anemia and PNH.
Published in:
2002
By:
- Young, Neal S;
- Maciejewski, Jaroslaw P;
- Sloand, Elaine;
- Chen, Guiben;
- Zeng, Weihua;
- Risitano, Antonio;
- Miyazato, Akira
Publication type:
journal article
Immune pathophysiology of aplastic anemia.
Published in:
2002
By:
- Maciejewski, Jaroslaw P;
- Risitano, Antonio;
- Kook, Hoon;
- Zeng, Weihua;
- Chen, Guibin;
- Young, Neal S
Publication type:
journal article
Immunosuppressive treatment of acquired aplastic anemia and immune-mediated bone marrow failure syndromes.
Published in:
2002
By:
- Young, Neal;
- Young, Neal S
Publication type:
journal article
Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6143, doi. 10.3390/ijms21176143
By:
- Chen, Jichun;
- Zhang, Shuling;
- Feng, Xingmin;
- Wu, Zhijie;
- Dubois, Wendy;
- Thovarai, Vishal;
- Ahluwalia, Sonia;
- Gao, Shouguo;
- Chen, Jinguo;
- Peat, Tyler;
- Sen, Shurjo K.;
- Trinchieri, Giorgio;
- Young, Neal S.;
- Mock, Beverly A.
Publication type:
Article
Comprehensive network modeling from single cell RNA sequencing of human and mouse reveals well conserved transcription regulation of hematopoiesis.
Published in:
BMC Genomics, 2020, v. 21, p. 1, doi. 10.1186/s12864-020-07241-2
By:
- Gao, Shouguo;
- Wu, Zhijie;
- Feng, Xingmin;
- Kajigaya, Sachiko;
- Wang, Xujing;
- Young, Neal S.
Publication type:
Article
Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 1952, doi. 10.1172/JCI67146
By:
- Winkler, Thomas;
- So Gun Hong;
- Decker, Jake E.;
- Morgan, Mary J.;
- Chuanfeng Wu;
- Hughes V, William M.;
- Yanqin Yang;
- Wangsa, Danny;
- Padilla-Nash, Hesed M.;
- Ried, Thomas;
- Young, Neal S.;
- Dunbar, Cynthia E.;
- Calado, Rodrigo T.
Publication type:
Article
Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors.
Published in:
2010
By:
- Zhihong Wan;
- Ning Zhi;
- Wong, Susan;
- Keyvanfar, Keyvan;
- Delong Liu;
- Raghavachari, Nalini;
- Munson, Peter J.;
- Su Su;
- Malide, Daniela;
- Kajigaya, Sachiko;
- Young, Neal S.;
- Wan, Zhihong;
- Zhi, Ning;
- Liu, Delong;
- Su, Su
Publication type:
journal article
The Immune System as Mediator of Virus-Associated Bone Marrow Failure: B19 Parvovirus and Epstein-Barr Virus.
Published in:
Annals of the New York Academy of Sciences, 1989, v. 554, n. 1, p. 75, doi. 10.1111/j.1749-6632.1989.tb22411.x
By:
- YOUNG, NEAL S.;
- BARANSKI, BRUCE;
- KURTZMAN, GARY
Publication type:
Article
Novel Surrogate Neutralizing Assay Supports Parvovirus B19 Vaccine Development for Children with Sickle Cell Disease.
Published in:
Vaccines, 2021, v. 9, n. 8, p. 860, doi. 10.3390/vaccines9080860
By:
- Penkert, Rhiannon R.;
- Chandramouli, Sumana;
- Dormitzer, Philip R.;
- Settembre, Ethan C.;
- Sealy, Robert E.;
- Wong, Susan;
- Young, Neal S.;
- Sun, Yilun;
- Tang, Li;
- Cotton, Alyssa;
- Dowdy, Jola;
- Hayden, Randall T.;
- Hankins, Jane S.;
- Hurwitz, Julia L.
Publication type:
Article
Single-cell RNA sequencing coupled to TCR profiling of large granular lymphocyte leukemia T cells.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29175-x
By:
- Gao, Shouguo;
- Wu, Zhijie;
- Arnold, Bradley;
- Diamond, Carrie;
- Batchu, Sai;
- Giudice, Valentina;
- Alemu, Lemlem;
- Raffo, Diego Quinones;
- Feng, Xingmin;
- Kajigaya, Sachiko;
- Barrett, John;
- Ito, Sawa;
- Young, Neal S.
Publication type:
Article
Flaviviruses and Bone Marrow Failure.
Published in:
JAMA: Journal of the American Medical Association, 1990, v. 263, n. 22, p. 3065, doi. 10.1001/jama.1990.03440220089037
By:
- Young, Neal S.
Publication type:
Article
Gamma--Interferon Gene Expression in the Bone Marrow of Patients with Aplastic Anemia.
Published in:
Annals of Internal Medicine, 1994, v. 120, n. 6, p. 463, doi. 10.7326/0003-4819-120-6-199403150-00003
By:
- Nistico, Antonio;
- Young, Neal S.
Publication type:
Article
Persistent B19 parvovirus infection in patients infected with human immunodeficiency virus type 1 (HIV-1): a treatable cause of anemia in AIDS.
Published in:
1990
By:
- Frickhofen, Norbert;
- Abkowitz, Janis L.;
- Safford, Monika;
- Berry, Michael;
- Antunez-de-Mayolo, Jorge;
- Astrow, Alan;
- Cohen, Robert;
- Halperin, Ira;
- King, Lambert;
- Mintzer, David;
- Cohen, Bernard;
- Young, Neal S.;
- Frickhofen, N;
- Abkowitz, J L;
- Safford, M;
- Berry, J M;
- Antunez-de-Mayolo, J;
- Astrow, A;
- Cohen, R;
- Halperin, I
Publication type:
journal article
Epstein-Barr virus in the bone marrow of patients with aplastic anemia.
Published in:
1988
By:
- Baranski, Bruce;
- Armstrong, Gary;
- Truman, John T.;
- Quinnan Jr., Gerald V.;
- Straus, Stephen E.;
- Young, Neal S.;
- Baranski, B;
- Armstrong, G;
- Truman, J T;
- Quinnan, G V Jr;
- Straus, S E;
- Young, N S
Publication type:
journal article
Immunologic Abnormalities in Patients Receiving Multiple Blood Transfusions.
Published in:
Annals of Internal Medicine, 1984, v. 100, n. 2, p. 173, doi. 10.7326/0003-4819-100-2-173
By:
- Gascon, Pedro;
- Zoumbos, Nicholas C.;
- Young, Neal S.
Publication type:
Article
Mitochondrial DNA Sequence Heterogeneity of Single CD34+ Cells After Nonmyeloablative Allogeneic Stem Cell Transplantation.
Published in:
Stem Cells, 2007, v. 25, n. 10, p. 2670, doi. 10.1634/stemcells.2007-0269
By:
- Yong-Gang Yao;
- Childs, Richard W.;
- Kajigaya, Sachiko;
- McCoy Jr., J. Philip;
- Young, Neal S.
Publication type:
Article
Investigation of SEN Virus Infection in Patients with Cryptogenic Acute Liver Failure, Hepatitis-Associated Aplastic Anemia, or Acute and Chronic Non--A--E Hepatitis.
Published in:
Journal of Infectious Diseases, 2003, v. 188, n. 10, p. 1545, doi. 10.1086/379216
By:
- Umemura, Takeji;
- Tanaka, Eiji;
- Ostapowicz, George;
- Brown, Kevin E.;
- Heringlake, Stefan;
- Tassopoulos, Nicolaos C.;
- Wang, Richard Y.-H.;
- Yeo, Anthony E.T.;
- Shih, J. Wai-Kuo;
- Orii, Koji;
- Young, Neal S.;
- Hatzakis, Angelos;
- Manns, Michael P.;
- Lee, William M.;
- Kiyosawa, Kendo;
- Alter, Harvey J.
Publication type:
Article
Prevalence of Parvovirus B19 in Liver Tissue: No Association with Fulminant Hepatitis or Hepatitis-Associated Aplastic Anemia.
Published in:
Journal of Infectious Diseases, 2003, v. 187, n. 10, p. 1581, doi. 10.1086/374781
By:
- Wong, Susan;
- Young, Neal S.;
- Brown, Kevin E.
Publication type:
Article
Safety and Immunogenicity of a Recombinant Parvovirus B19 Vaccine Formulated with MF59C.1.
Published in:
Journal of Infectious Diseases, 2003, v. 187, n. 4, p. 675, doi. 10.1086/368382
By:
- Ballou, W. Ripley;
- Reed, Jennifer L.;
- Noble, William;
- Young, Neal S.;
- Koenig, Scott
Publication type:
Article
Quantitative Analysis of Neutralizing Immune Responses to Human Parvovirus B19 Using a Novel Reverse Transcriptase-Polymerase Chain Reaction-Based Assay.
Published in:
Journal of Infectious Diseases, 1999, v. 179, n. 3, p. 619, doi. 10.1086/314648
By:
- Bostic, Jennifer Reed;
- Brown, Kevin E.;
- Young, Neal S.;
- Koenig, Scott
Publication type:
Article
High Prevalence of GB Virus C/Hepatitis G Virus in Healthy Persons in Ho Chi Minh City, Vietnam.
Published in:
Journal of Infectious Diseases, 1997, v. 175, n. 2, p. 450
By:
- Brown, Kevin E.;
- Wong, Susan;
- Buu, Mat;
- Binh, Tran V.;
- Be, Tran V.;
- Young, Neal S.
Publication type:
Article
Candidate Recombinant Vaccine for Human B19 Parvovirus.
Published in:
Journal of Infectious Diseases, 1993, v. 167, n. 5, p. 1034, doi. 10.1093/infdis/167.5.1034
By:
- Bansal, Geetha P.;
- Hatfield, Jacqueline A.;
- Dunn, Frances E.;
- Kramer, Andrew A.;
- Brady, Francine;
- Riggin, Charles H.;
- Collett, Marc S.;
- Yoshimoto, Kohji;
- Kajigaya, Sachiko;
- Young, Neal S.
Publication type:
Article
Safety and efficacy of immunosuppressive therapy for elderly patients with severe aplastic anaemia.
Published in:
British Journal of Haematology, 2024, v. 205, n. 3, p. 1170, doi. 10.1111/bjh.19648
By:
- Prabahran, Ashvind;
- Durrani, Jibran;
- Coelho‐Da Silva, Juan;
- Shalhoub, Ruba;
- Lotter, Jennifer;
- Rios, Olga;
- Ritchie, David S.;
- Wu, Colin O.;
- Patel, Bhavisha A.;
- Young, Neal S.;
- Groarke, Emma M.
Publication type:
Article
Ahemolytic PNH (white cell PNH): Clinical features and implications of a distinct phenotype of paroxysmal nocturnal haemoglobinuria.
Published in:
British Journal of Haematology, 2024, v. 204, n. 5, p. 2121, doi. 10.1111/bjh.19395
By:
- Tombul, Zehra;
- Bahaj, Waled;
- Ozturk, Merve;
- Patel, Bhavisha;
- Toprak, Ahmet;
- Ibrahim, Ibrahim;
- Chen, Weina;
- Fuda, Franklin;
- Ogbue, Olisaemeka D.;
- Gurnari, Carmelo;
- Parker, Charles;
- Young, Neal S.;
- Maciejewski, Jaroslaw P.;
- Duran, Munevver;
- Bat, Taha
Publication type:
Article
Towards treatments for VEXAS.
Published in:
British Journal of Haematology, 2022, v. 196, n. 4, p. 804, doi. 10.1111/bjh.17930
By:
- Patel, Bhavisha A.;
- Young, Neal S.
Publication type:
Article
COVID‐19 infection in patients with severe aplastic anaemia.
Published in:
British Journal of Haematology, 2021, v. 193, n. 5, p. 902, doi. 10.1111/bjh.17415
By:
- Paton, Casey;
- Mathews, Liza;
- Groarke, Emma M.;
- Rios, Olga;
- Lotter, Jennifer;
- Patel, Bhavisha A.;
- Young, Neal S.
Publication type:
Article
Eltrombopag added to immunosuppression for children with treatment‐naïve severe aplastic anaemia.
Published in:
British Journal of Haematology, 2021, v. 192, n. 3, p. 605, doi. 10.1111/bjh.17232
By:
- Groarke, Emma M.;
- Patel, Bhavisha A.;
- Gutierrez‐Rodrigues, Fernanda;
- Rios, Olga;
- Lotter, Jennifer;
- Baldoni, Daniela;
- St. Pierre, Annie;
- Shalhoub, Ruba;
- Wu, Colin O.;
- Townsley, Danielle M.;
- Young, Neal S.
Publication type:
Article
Deficit of circulating CD19+CD24hiCD38hi regulatory B cells in severe aplastic anaemia.
Published in:
British Journal of Haematology, 2020, v. 190, n. 4, p. 610, doi. 10.1111/bjh.16651
By:
- Zaimoku, Yoshitaka;
- Patel, Bhavisha A.;
- Kajigaya, Sachiko;
- Feng, Xingmin;
- Alemu, Lemlem;
- Quinones Raffo, Diego;
- Groarke, Emma M.;
- Young, Neal S.
Publication type:
Article
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes.
Published in:
British Journal of Haematology, 2017, v. 177, n. 1, p. 136, doi. 10.1111/bjh.14502
By:
- Hosokawa, Kohei;
- Kajigaya, Sachiko;
- Keyvanfar, Keyvan;
- Qiao, Wangmin;
- Xie, Yanling;
- Biancotto, Angelique;
- Townsley, Danielle M.;
- Feng, Xingmin;
- Young, Neal S.
Publication type:
Article
Allogeneic transplantation using CD34+ selected peripheral blood progenitor cells combined with non-mobilized donor T cells for refractory severe aplastic anaemia.
Published in:
British Journal of Haematology, 2017, v. 176, n. 6, p. 950, doi. 10.1111/bjh.14448
By:
- Purev, Enkhtsetseg;
- Tian, Xin;
- Aue, Georg;
- Pantin, Jeremy;
- Vo, Phuong;
- Shalabi, Reem;
- Reger, Robert N.;
- Cook, Lisa;
- Ramos, Catalina;
- Cho, Elena;
- Worthy, Tat'yana;
- Khuu, Hanh;
- Stroncek, David;
- Young, Neal S.;
- Childs, Richard W.
Publication type:
Article
Epigenetic landscape of the TERT promoter: a potential biomarker for high risk AML/ MDS.
Published in:
British Journal of Haematology, 2016, v. 175, n. 3, p. 427, doi. 10.1111/bjh.14244
By:
- Zhao, Xin;
- Tian, Xin;
- Kajigaya, Sachiko;
- Cantilena, Caroline R.;
- Strickland, Stephen;
- Savani, Bipin N.;
- Mohan, Sanjay;
- Feng, Xingmin;
- Keyvanfar, Keyvan;
- Dunavin, Neil;
- Townsley, Danielle M.;
- Dumitriu, Bogdan;
- Battiwalla, Minoo;
- Rezvani, Katayoun;
- Young, Neal S.;
- Barrett, A. John;
- Ito, Sawa
Publication type:
Article
A trial of immunotherapy in aplastic anemia and pure red cell aplasia.
Published in:
Journal of Clinical Apheresis, 1983, v. 1, n. 2, p. 95, doi. 10.1002/jca.2920010206
By:
- Young, Neal S.;
- Klein, Harvey G.;
- Griffith, Patricia;
- Nienhuis, Arthur W.
Publication type:
Article
Alemtuzumab in relapsed immune severe aplastic anemia: Long‐term results of a phase II study.
Published in:
American Journal of Hematology, 2023, v. 98, n. 6, p. 932, doi. 10.1002/ajh.26924
By:
- Aggarwal, Nidhi;
- Manley, Ash Lee;
- Shalhoub, Ruba;
- Durrani, Jibran;
- Rios, Olga;
- Lotter, Jennifer;
- Patel, Bhavisha A.;
- Wu, Colin O.;
- Young, Neal S.;
- Groarke, Emma M.
Publication type:
Article
Long‐term eltrombopag for bone marrow failure depletes iron.
Published in:
American Journal of Hematology, 2022, v. 97, n. 6, p. 791, doi. 10.1002/ajh.26543
By:
- Young, David J.;
- Fan, Xing;
- Groarke, Emma M.;
- Patel, Bhavisha;
- Desmond, Ronan;
- Winkler, Thomas;
- Larochelle, Andre;
- Calvo, Katherine R.;
- Young, Neal S.;
- Dunbar, Cynthia E.
Publication type:
Article
Gram-negative sepsis: detection of endotoxemia with the limulus test. With studies of associated changes in blood coagulation, serum lipids, and complement.
Published in:
1972
By:
- Levin, Jack;
- Poore, Edwin;
- Young, Neal S.;
- Margolis, Simeon;
- Zauber, Neil P.;
- Townes, Alexander S.;
- Bell, William R.;
- Levin, J;
- Poore, T E;
- Young, N S;
- Margolis, S;
- Zauber, N P;
- Townes, A S;
- Bell, W R
Publication type:
journal article
Parvovirus B19 Empty Capsids as Antigen Carriers for Presentation of Antigenic Determinants of Dengue 2 Virus.
Published in:
Journal of Infectious Diseases, 2006, v. 194, n. 6, p. 790, doi. 10.1086/506361
By:
- Amexis, Georgios;
- Young, Neal S.
Publication type:
Article
A novel homozygous RTEL1 variant in a consanguineous Lebanese family: phenotypic heterogeneity and disease anticipation.
Published in:
Human Genetics, 2019, v. 138, n. 11/12, p. 1323, doi. 10.1007/s00439-019-02076-8
By:
- Gutierrez-Rodrigues, Fernanda;
- Masri, Nohad;
- Chouery, Eliane;
- Diamond, Carrie;
- Jalkh, Nadine;
- Vicente, Alana;
- Kajigaya, Sachiko;
- Abillama, Fayez;
- Bejjani, Noha;
- Serhal, Wassim;
- Calado, Rodrigo T.;
- Young, Neal S.;
- Farhat, Hussein;
- Coussa, Marie Louise
Publication type:
Article
CellCallEXT: Analysis of Ligand–Receptor and Transcription Factor Activities in Cell–Cell Communication of Tumor Immune Microenvironment.
Published in:
Cancers, 2022, v. 14, n. 19, p. 4957, doi. 10.3390/cancers14194957
By:
- Gao, Shouguo;
- Feng, Xingmin;
- Wu, Zhijie;
- Kajigaya, Sachiko;
- Young, Neal S.
Publication type:
Article
Optimization and standardization of fluorescent cell barcoding for multiplexed flow cytometric phenotyping.
Published in:
Cytometry. Part A, 2017, v. 91, n. 7, p. 694, doi. 10.1002/cyto.a.23162
By:
- Giudice, Valentina;
- Feng, Xingmin;
- Kajigaya, Sachiko;
- Young, Neal S.;
- Biancotto, Angélique
Publication type:
Article
Telomere content measurement in human hematopoietic cells: Comparative analysis of qPCR and Flow-FISH techniques.
Published in:
Cytometry. Part A, 2016, v. 89, n. 10, p. 914, doi. 10.1002/cyto.a.22982
By:
- Wand, Taylor;
- Fang, Mike;
- Chen, Christina;
- Hardy, Nathan;
- McCoy, J. Philip;
- Dumitriu, Bogdan;
- Young, Neal S.;
- Biancotto, Angélique
Publication type:
Article
Minimal role of interleukin 6 and toll-like receptor 2 and 4 in murine models of immune-mediated bone marrow failure.
Published in:
PLoS ONE, 2021, v. 16, n. 3, p. 1, doi. 10.1371/journal.pone.0248343
By:
- Solorzano, Sabrina;
- Kim, Jisoo;
- Chen, Jichun;
- Feng, Xingmin;
- Young, Neal S.
Publication type:
Article
Bone Marrow as a Source of Cells for Paroxysmal Nocturnal Hemoglobinuria Detection.
Published in:
2018
By:
- Dulau-Florea, Alina E;
- Young, Neal S;
- Maric, Irina;
- Calvo, Katherine R;
- Dunbar, Cynthia E;
- Townsley, Danielle M;
- Winkler, Thomas;
- Monreal, Mariela;
- Jiang, Chunjie;
- Jordan, Elaine K;
- Braylan, Raul C
Publication type:
journal article
Sirolimus augments hematopoietic stem and progenitor cell regeneration following hematopoietic insults.
Published in:
Stem Cells, 2021, v. 39, n. 2, p. 240, doi. 10.1002/stem.3313
By:
- Lin, Zenghua;
- Hollinger, Maile K.;
- Wu, Zhijie;
- Sun, Wanling;
- Batey, Kaylind;
- Kim, Jisoo;
- Chen, Jichun;
- Feng, Xingmin;
- Young, Neal S.
Publication type:
Article
Peromyscus leucopus mice: a potential animal model for haematological studies.
Published in:
International Journal of Experimental Pathology, 2014, v. 95, n. 5, p. 342, doi. 10.1111/iep.12091
By:
- Sun, Yu;
- Desierto, Marie J.;
- Ueda, Yasutaka;
- Kajigaya, Sachiko;
- Chen, Jichun;
- Young, Neal S.
Publication type:
Article
Pharmacological Manipulation of Fetal Hemoglobin Synthesis in Patients with Severe β-Thalassemia.
Published in:
Annals of the New York Academy of Sciences, 1985, v. 445, n. 1, p. 198, doi. 10.1111/j.1749-6632.1985.tb17189.x
By:
- NIENHUIS, ARTHUR W.;
- LEY, TIMOTHY J.;
- HUMPHRIES, R. KEITH;
- YOUNG, NEAL S.;
- DOVER, GEORGE
Publication type:
Article

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