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DNA/RNA heteroduplex oligonucleotide technology for regulating lymphocytes in vivo.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26902-8
By:
- Ohyagi, Masaki;
- Nagata, Tetsuya;
- Ihara, Kensuke;
- Yoshida-Tanaka, Kie;
- Nishi, Rieko;
- Miyata, Haruka;
- Abe, Aya;
- Mabuchi, Yo;
- Akazawa, Chihiro;
- Yokota, Takanori
Publication type:
Article
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS.
Published in:
Nature Biotechnology, 2021, v. 39, n. 12, p. 1529, doi. 10.1038/s41587-021-00972-x
By:
- Nagata, Tetsuya;
- Dwyer, Chrissa A.;
- Yoshida-Tanaka, Kie;
- Ihara, Kensuke;
- Ohyagi, Masaki;
- Kaburagi, Hidetoshi;
- Miyata, Haruka;
- Ebihara, Satoe;
- Yoshioka, Kotaro;
- Ishii, Takashi;
- Miyata, Kanjiro;
- Miyata, Kenichi;
- Powers, Berit;
- Igari, Tomoko;
- Yamamoto, Syunsuke;
- Arimura, Naoto;
- Hirabayashi, Hideki;
- Uchihara, Toshiki;
- Hara, Rintaro Iwata;
- Wada, Takeshi
Publication type:
Article
Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route.
Published in:
Scientific Reports, 2015, p. 17035, doi. 10.1038/srep17035
By:
- Murakami, Masahiro;
- Nishina, Kazutaka;
- Watanabe, Chie;
- Yoshida-Tanaka, Kie;
- Piao, Wenying;
- Kuwahara, Hiroya;
- Horikiri, Yuji;
- Miyata, Kanjiro;
- Nishiyama, Nobuhiro;
- Kataoka, Kazunori;
- Yoshida, Masayuki;
- Mizusawa, Hidehiro;
- Yokota, Takanori
Publication type:
Article
Intrathecal AAV Serotype 9-mediated Delivery of shRNA Against TRPV1 Attenuates Thermal Hyperalgesia in a Mouse Model of Peripheral Nerve Injury.
Published in:
Molecular Therapy, 2014, v. 22, n. 2, p. 409, doi. 10.1038/mt.2013.247
By:
- Hirai, Takashi;
- Enomoto, Mitsuhiro;
- Kaburagi, Hidetoshi;
- Sotome, Shinichi;
- Yoshida-Tanaka, Kie;
- Ukegawa, Madoka;
- Kuwahara, Hiroya;
- Yamamoto, Mariko;
- Tajiri, Mio;
- Miyata, Haruka;
- Hirai, Yukihiko;
- Tominaga, Makoto;
- Shinomiya, Kenichi;
- Mizusawa, Hidehiro;
- Okawa, Atsushi;
- Yokota, Takanori
Publication type:
Article
Effects of local reduction of endogenous α-synuclein using antisense oligonucleotides on the fibril-induced propagation of pathology through the neural network in wild-type mice.
Published in:
Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01766-3
By:
- Sano, Tatsuhiko;
- Nagata, Tetsuya;
- Ebihara, Satoe;
- Yoshida-Tanaka, Kie;
- Nakamura, Ayako;
- Sasaki, Asuka;
- Shimozawa, Aki;
- Mochizuki, Hideki;
- Uchihara, Toshiki;
- Hasegawa, Masato;
- Yokota, Takanori
Publication type:
Article
DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing.
Published in:
Nature Communications, 2015, v. 6, n. 8, p. 7969, doi. 10.1038/ncomms8969
By:
- Nishina, Kazutaka;
- Piao, Wenying;
- Yoshida-Tanaka, Kie;
- Sujino, Yumiko;
- Nishina, Tomoko;
- Yamamoto, Tsuyoshi;
- Nitta, Keiko;
- Yoshioka, Kotaro;
- Kuwahara, Hiroya;
- Yasuhara, Hidenori;
- Baba, Takeshi;
- Ono, Fumiko;
- Miyata, Kanjiro;
- Miyake, Koichi;
- Seth, Punit P.;
- Low, Audrey;
- Yoshida, Masayuki;
- Bennett, C. Frank;
- Kataoka, Kazunori;
- Mizusawa, Hidehiro
Publication type:
Article
Short DNA/RNA heteroduplex oligonucleotide interacting proteins are key regulators of target gene silencing.
Published in:
Nucleic Acids Research, 2021, v. 49, n. 9, p. 4864, doi. 10.1093/nar/gkab258
By:
- Asada, Ken;
- Sakaue, Fumika;
- Nagata, Tetsuya;
- Zhang, Ji-chun;
- Yoshida-Tanaka, Kie;
- Abe, Aya;
- Nawa, Makiko;
- Nishina, Kazutaka;
- Yokota, Takanori
Publication type:
Article
Highly efficient silencing of microRNA by heteroduplex oligonucleotides.
Published in:
Nucleic Acids Research, 2019, v. 47, n. 14, p. 7321, doi. 10.1093/nar/gkz492
By:
- Yoshioka, Kotaro;
- Kunieda, Taiki;
- Asami, Yutaro;
- Guo, Huijia;
- Miyata, Haruka;
- Yoshida-Tanaka, Kie;
- Sujino, Yumiko;
- Piao, Wenying;
- Kuwahara, Hiroya;
- Nishina, Kazutaka;
- Hara, Rintaro Iwata;
- Nagata, Tetsuya;
- Wada, Takeshi;
- Obika, Satoshi;
- Yokota, Takanori
Publication type:
Article
Highly efficient gene silencing in mouse brain by overhanging‐duplex oligonucleotides via intraventricular route.
Published in:
FEBS Letters, 2020, v. 594, n. 9, p. 1413, doi. 10.1002/1873-3468.13742
By:
- Lei Mon, Su Su;
- Yoshioka, Kotaro;
- Jia, Chunyan;
- Kunieda, Taiki;
- Asami, Yutaro;
- Yoshida‐Tanaka, Kie;
- Piao, Wenying;
- Kuwahara, Hiroya;
- Nishina, Kazutaka;
- Nagata, Tetsuya;
- Yokota, Takanori
Publication type:
Article
Heteroduplex oligonucleotide technology boosts oligonucleotide splice switching activity of morpholino oligomers in a Duchenne muscular dystrophy mouse model.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48204-5
By:
- Hasegawa, Juri;
- Nagata, Tetsuya;
- Ihara, Kensuke;
- Tanihata, Jun;
- Ebihara, Satoe;
- Yoshida-Tanaka, Kie;
- Yanagidaira, Mitsugu;
- Ohara, Masahiro;
- Sasaki, Asuka;
- Nakayama, Miyu;
- Yamamoto, Syunsuke;
- Ishii, Takashi;
- Iwata-Hara, Rintaro;
- Naito, Mitsuru;
- Miyata, Kanjiro;
- Sakaue, Fumika;
- Yokota, Takanori
Publication type:
Article

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