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Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34753-0
By:
- Wei, Bingyan;
- Zhang, Tao;
- Wang, Pengyu;
- Pan, Yihui;
- Li, Jiahui;
- Chen, Weizhong;
- Zhang, Min;
- Ji, Quanjiang;
- Wu, Wenjuan;
- Lan, Lefu;
- Gan, Jianhua;
- Yang, Cai-Guang
Publication type:
Article
A Rhein‐Based Rh(III) Arene Complex with Anti‐tumor Cell Proliferative Activity Inhibits RNA Demethylase FTO.
Published in:
Chinese Journal of Chemistry, 2022, v. 40, n. 10, p. 1156, doi. 10.1002/cjoc.202100901
By:
- Liu, Lu;
- Kong, Yaqiong;
- He, Liang;
- Wang, Xiuxiu;
- Wang, Meng‐Meng;
- Xu, Hongjiao;
- Yang, Cai‐Guang;
- Su, Zhi;
- Zhao, Jing;
- Mao, Zong‐Wan;
- Huang, Yue;
- Liu, Hong‐Ke
Publication type:
Article
Synthesis and Structure‐Activity Relationships of Ring‐Opened Bengamide Analogues against Methicillin‐ResistantStaphylococcus aureus†.
Published in:
Chinese Journal of Chemistry, 2021, v. 39, n. 3, p. 671, doi. 10.1002/cjoc.202000502
By:
- Yu, Chen‐Xi;
- Wei, Bing‐Yan;
- Kong, Xue‐Qing;
- Yang, Cai‐Guang;
- Nan, Fa‐Jun
Publication type:
Article
A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP‐Protein Interactions in Kidney Cancer Cells.
Published in:
Chinese Journal of Chemistry, 2021, v. 39, n. 2, p. 274, doi. 10.1002/cjoc.202000462
By:
- Wang, Zhen;
- Zhang, Hao;
- Chen, Baoen;
- Ouyang, Sisheng;
- Zheng, Tong;
- Zhou, Ran;
- Dong, Ze;
- Huang, Yue;
- Zhang, Tao;
- Jiang, Hualiang;
- Gan, Jianhua;
- Luo, Cheng;
- Yang, Cai‐Guang
Publication type:
Article
Design, Synthesis and Biological Evaluation of Bengamide Analogues as ClpP Activators.
Published in:
Chinese Journal of Chemistry, 2020, v. 38, n. 10, p. 1111, doi. 10.1002/cjoc.202000133
By:
- Kong, Xue‐Qing;
- Wei, Bing‐Yan;
- Yu, Chen‐Xi;
- Guan, Xiang‐Na;
- Ma, Wei‐Ping;
- Liu, Gang;
- Yang, Cai‐Guang;
- Nan, Fa‐Jun
Publication type:
Article
RNA Methylation m6A: A New Code and Drug Target?
Published in:
Chinese Journal of Chemistry, 2020, v. 38, n. 4, p. 420, doi. 10.1002/cjoc.201900490
By:
- Lai, Gan‐Qiang;
- Zhou, Lin‐Lin;
- Yang, Cai‐Guang
Publication type:
Article
Chemical Intervention on Staphylococcus aureus Virulence.
Published in:
Chinese Journal of Chemistry, 2019, v. 37, n. 2, p. 183, doi. 10.1002/cjoc.201800470
By:
- Zhou, Lin‐Lin;
- Yang, Cai‐Guang
Publication type:
Article
Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus.
Published in:
PLoS Pathogens, 2024, v. 20, n. 7, p. 1, doi. 10.1371/journal.ppat.1012425
By:
- Chen, Feifei;
- Zhao, Qingmin;
- Yang, Ziqiong;
- Chen, Rongrong;
- Pan, Huiwen;
- Wang, Yanhui;
- Liu, Huan;
- Cao, Qiao;
- Gan, Jianhua;
- Liu, Xia;
- Zhang, Naixia;
- Yang, Cai-Guang;
- Liang, Haihua;
- Lan, Lefu
Publication type:
Article
Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR.
Published in:
EMBO Reports, 2010, v. 11, n. 9, p. 717, doi. 10.1038/embor.2010.129
By:
- Chen, Hao;
- Yi, Chengqi;
- Zhang, Jin;
- Zhang, Wenru;
- Ge, Zhiyun;
- Yang, Cai-Guang;
- He, Chuan
Publication type:
Article
Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR.
Published in:
EMBO Reports, 2010, v. 11, n. 9, p. 685, doi. 10.1038/embor.2010.96
By:
- Chen, Hao;
- Yi, Chengqi;
- Zhang, Jin;
- Zhang, Wenru;
- Ge, Zhiyun;
- Yang, Cai-Guang;
- He, Chuan
Publication type:
Article
Multi-omics for COVID-19: driving development of therapeutics and vaccines.
Published in:
National Science Review, 2023, v. 10, n. 9, p. 1, doi. 10.1093/nsr/nwad161
By:
- Guo, Mengyu;
- Xiong, Muya;
- Peng, Jinying;
- Guan, Tong;
- Su, Haixia;
- Huang, Yanyi;
- Yang, Cai-Guang;
- Li, Yang;
- Boraschi, Diana;
- Pillaiyar, Thanigaimalai;
- Wang, Guanbo;
- Yi, Chengqi;
- Xu, Yechun;
- Chen, Chunying
Publication type:
Article
Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.
Published in:
Nucleic Acids Research, 2015, v. 43, n. 1, p. 373, doi. 10.1093/nar/gku1276
By:
- Huang, Yue;
- Yan, Jingli;
- Li, Qi;
- Li, Jiafei;
- Gong, Shouzhe;
- Zhou, Hu;
- Gan, Jianhua;
- Jiang, Hualiang;
- Jia, Gui-Fang;
- Luo, Cheng;
- Yang, Cai-Guang
Publication type:
Article
Targeting SPOP with small molecules provides a novel strategy for kidney cancer therapy.
Published in:
SCIENCE CHINA Life Sciences, 2017, v. 60, n. 1, p. 91, doi. 10.1007/s11427-016-0297-2
By:
- Zheng, Tong;
- Yang, Cai-Guang
Publication type:
Article
Duplex interrogation by a direct DNA repair protein in search of base damage.
Published in:
Nature Structural & Molecular Biology, 2012, v. 19, n. 7, p. 671, doi. 10.1038/nsmb.2320
By:
- Yi, Chengqi;
- Chen, Baoen;
- Qi, Bo;
- Zhang, Wen;
- Jia, Guifang;
- Zhang, Liang;
- Li, Charles J;
- Dinner, Aaron R;
- Yang, Cai-Guang;
- He, Chuan
Publication type:
Article
Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42784-4
By:
- Zhou, Lin-Lin;
- Zhang, Tao;
- Xue, Yun;
- Yue, Chuan;
- Pan, Yihui;
- Wang, Pengyu;
- Yang, Teng;
- Li, Meixia;
- Zhou, Hu;
- Ding, Kan;
- Gan, Jianhua;
- Ji, Hongbin;
- Yang, Cai-Guang
Publication type:
Article
Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus.
Published in:
Molecular Microbiology, 2020, v. 114, n. 3, p. 423, doi. 10.1111/mmi.14519
By:
- Yang, Nana;
- Cao, Qiao;
- Hu, Shuyang;
- Xu, Chenchen;
- Fan, Ke;
- Chen, Feifei;
- Yang, Cai‐Guang;
- Liang, Haihua;
- Wu, Min;
- Bae, Taeok;
- Lan, Lefu
Publication type:
Article
Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa.
Published in:
Molecular Microbiology, 2016, v. 100, n. 5, p. 749, doi. 10.1111/mmi.13346
By:
- Chen, Weizhong;
- Wang, Dan;
- Zhou, Wenquan;
- Sang, Hong;
- Liu, Xichun;
- Ge, Zhiyun;
- Zhang, Jin;
- Lan, Lefu;
- Yang, Cai‐Guang;
- Chen, Hao
Publication type:
Article
The Crc protein participates in down-regulation of the Lon gene to promote rhamnolipid production and rhl quorum sensing in P seudomonas aeruginosa.
Published in:
Molecular Microbiology, 2015, v. 96, n. 3, p. 526, doi. 10.1111/mmi.12954
By:
- Yang, Nana;
- Ding, Shuting;
- Chen, Feifei;
- Zhang, Xue;
- Xia, Yongjie;
- Di, Hongxia;
- Cao, Qiao;
- Deng, Xin;
- Wu, Min;
- Wong, Catherine C.L.;
- Tian, Xiao‐Xu;
- Yang, Cai‐Guang;
- Zhao, Jing;
- Lan, Lefu
Publication type:
Article
Detection of 5-Hydroxymethylcytosine in DNA by Transferring a Keto-Glucose by Using T4 Phage β-Glucosyltransferase.
Published in:
ChemBioChem, 2011, v. 12, n. 11, p. 1682, doi. 10.1002/cbic.201100278
By:
- Song, Chun-Xiao;
- Sun, Yao;
- Dai, Qing;
- Lu, Xing-Yu;
- Yu, Miao;
- Yang, Cai-Guang;
- He, Chuan
Publication type:
Article
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Published in:
Nature, 2008, v. 452, n. 7190, p. 961, doi. 10.1038/nature06889
By:
- Yang, Cai-Guang;
- Yi, Chengqi;
- Duguid, Erica M.;
- Sullivan, Christopher T.;
- Jian, Xing;
- Rice, Phoebe A.;
- He, Chuan
Publication type:
Article
A Novel Signal Transduction Pathway that Modulates rhl Quorum Sensing and Bacterial Virulence in Pseudomonas aeruginosa.
Published in:
PLoS Pathogens, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.ppat.1004340
By:
- Cao, Qiao;
- Wang, Yue;
- Chen, Feifei;
- Xia, Yongjie;
- Lou, Jingyu;
- Zhang, Xue;
- Yang, Nana;
- Sun, Xiaoxu;
- Zhang, Qin;
- Zhuo, Chao;
- Huang, Xi;
- Deng, Xin;
- Yang, Cai-Guang;
- Ye, Yan;
- Zhao, Jing;
- Wu, Min;
- Lan, Lefu
Publication type:
Article
Mutation-induced remodeling of the BfmRS two-component system in Pseudomonas aeruginosa clinical isolates.
Published in:
Science Signaling, 2020, v. 13, n. 656, p. 1, doi. 10.1126/scisignal.aaz1529
By:
- Cao, Qiao;
- Yang, Nana;
- Wang, Yanhui;
- Xu, Chenchen;
- Zhang, Xue;
- Fan, Ke;
- Chen, Feifei;
- Liang, Haihua;
- Zhang, Yingchao;
- Deng, Xin;
- Feng, Youjun;
- Yang, Cai-Guang;
- Wu, Min;
- Bae, Taeok;
- Lan, Lefu
Publication type:
Article
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
Published in:
FEBS Letters, 2008, v. 582, n. 23/24, p. 3313, doi. 10.1016/j.febslet.2008.08.019
By:
- Jia, Guifang;
- Yang, Cai-Guang;
- Yang, Shangdong;
- Jian, Xing;
- Yi, Chengqi;
- Zhou, Zhiqiang;
- He, Chuan
Publication type:
Article
Damage Detection and Base Flipping in Direct DNA Alkylation Repair.
Published in:
ChemBioChem, 2009, v. 10, n. 3, p. 417, doi. 10.1002/cbic.200800580
By:
- Yang, Cai-Guang;
- Garcia, Kristel;
- He, Chuan
Publication type:
Article
Structure‐Activity Relationships of 2‐(Arylthio)benzoic Acid FTO Inhibitors.
Published in:
Israel Journal of Chemistry, 2024, v. 64, n. 3/4, p. 1, doi. 10.1002/ijch.202300166
By:
- Yan, Chao;
- Zhang, Qian;
- Xiao, Pan;
- Xie, Xinyun;
- Li, Ming;
- Qiu, Yuanlai;
- Wen, Liufa;
- Song, Xiaomin;
- Dong, Ze;
- Yang, Cai‐Guang
Publication type:
Article
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20820-x
By:
- Bernasocchi, Tiziano;
- El Tekle, Geniver;
- Bolis, Marco;
- Mutti, Azzurra;
- Vallerga, Arianna;
- Brandt, Laura P.;
- Spriano, Filippo;
- Svinkina, Tanya;
- Zoma, Marita;
- Ceserani, Valentina;
- Rinaldi, Anna;
- Janouskova, Hana;
- Bossi, Daniela;
- Cavalli, Manuela;
- Mosole, Simone;
- Geiger, Roger;
- Dong, Ze;
- Yang, Cai-Guang;
- Albino, Domenico;
- Rinaldi, Andrea
Publication type:
Article

Found: 26

Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.

A Rhein‐Based Rh(III) Arene Complex with Anti‐tumor Cell Proliferative Activity Inhibits RNA Demethylase FTO.

Synthesis and Structure‐Activity Relationships of Ring‐Opened Bengamide Analogues against Methicillin‐ResistantStaphylococcus aureus<sup>†</sup>.

A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP‐Protein Interactions in Kidney Cancer Cells.

Design, Synthesis and Biological Evaluation of Bengamide Analogues as ClpP Activators.

RNA Methylation m<sup>6</sup>A: A New Code and Drug Target?

Chemical Intervention on Staphylococcus aureus Virulence.

Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus.

Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR.

Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR.

Multi-omics for COVID-19: driving development of therapeutics and vaccines.

Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.

Targeting SPOP with small molecules provides a novel strategy for kidney cancer therapy.

Duplex interrogation by a direct DNA repair protein in search of base damage.

Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.

Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus.

Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa.

The Crc protein participates in down-regulation of the Lon gene to promote rhamnolipid production and rhl quorum sensing in P seudomonas aeruginosa.

Detection of 5-Hydroxymethylcytosine in DNA by Transferring a Keto-Glucose by Using T4 Phage β-Glucosyltransferase.

Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.

A Novel Signal Transduction Pathway that Modulates <i>rhl</i> Quorum Sensing and Bacterial Virulence in <i>Pseudomonas aeruginosa</i>.

Mutation-induced remodeling of the BfmRS two-component system in Pseudomonas aeruginosa clinical isolates.

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

Damage Detection and Base Flipping in Direct DNA Alkylation Repair.

Structure‐Activity Relationships of 2‐(Arylthio)benzoic Acid FTO Inhibitors.

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.