Found: 85
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Interrogation of the intersubunit interface of the open Hv1 proton channel with a probe of allosteric coupling.
- Published in:
- Scientific Reports, 2015, p. 14077, doi. 10.1038/srep14077
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- Publication type:
- Article
Toward high-resolution modeling of small molecule–ion channel interactions.
- Published in:
- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1411428
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- Publication type:
- Article
Activation of KCa3.1 by SKA-31 induces arteriolar dilatation and lowers blood pressure in normo- and hypertensive connexin40-deficient mice.
- Published in:
- 2013
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- Publication type:
- journal article
Activation of K<sub>Ca</sub>3.1 by SKA-31 induces arteriolar dilatation and lowers blood pressure in normo- and hypertensive connexin40-deficient mice.
- Published in:
- British Journal of Pharmacology, 2013, v. 170, n. 2, p. 293, doi. 10.1111/bph.12267
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- Publication type:
- Article
Pharmacological activation of KCa3.1/KCa2.3 channels produces endothelial hyperpolarization and lowers blood pressure in conscious dogs.
- Published in:
- British Journal of Pharmacology, 2012, v. 165, n. 1, p. 223, doi. 10.1111/j.1476-5381.2011.01546.x
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- Publication type:
- Article
The K+ channels K(Ca)3.1 and K(v)1.3 as novel targets for asthma therapy.
- Published in:
- 2009
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- Publication type:
- journal article
Enhancement of Endothelial KCa Channel Activity as a Novel Strategy to Oppose Atherosclerosis.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2908
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- Publication type:
- Article
Enhancement of Endothelial KCa Channel Activity as a Novel Strategy to Oppose Atherosclerosis.
- Published in:
- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02504
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- Publication type:
- Article
Kv1.3 channel-blocking immunomodulatory pep tides from parasitic worms: implications for autoimmune diseases.
- Published in:
- FASEB Journal, 2014, v. 28, n. 9, p. 3952, doi. 10.1096/fj.14-251967
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- Publication type:
- Article
KCa3.1 in the early stages of ischemic stroke (893.19).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.893.19
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- Publication type:
- Article
The vasoconstrictor agent phenylephrine selectively modulates endothelium‐ vs. smooth muscle‐mediated inhibition of myogenic tone in rat cremaster arteries (677.5).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.677.5
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- Publication type:
- Article
A pharmacologic activator of endothelial KCa channels improves coronary function in the hearts of type 2 diabetic rats (1078.10).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1078.10
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- Publication type:
- Article
Positive KCa channel gating modulators with selectivity for KCa3.1 (1057.6).
- Published in:
- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1057.6
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- Publication type:
- Article
Ca<sup>2+</sup>-Activated K<sup>+</sup> Channel-3.1 Blocker TRAM-34 Attenuates Airway Remodeling and Eosinophilia in a Murine Asthma Model.
- Published in:
- American Journal of Respiratory Cell & Molecular Biology, 2013, v. 48, n. 2, p. 212, doi. 10.1165/rcmb.2012-0103OC
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- Publication type:
- Article
Vascular dysfunctions in the isolated aorta of double-transgenic hypertensive mice developing aortic aneurysm.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2015, v. 467, n. 9, p. 1945, doi. 10.1007/s00424-014-1644-6
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- Publication type:
- Article
Preserved regulation of renal perfusion pressure by small and intermediate conductance K channels in hypertensive mice with or without renal failure.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2015, v. 467, n. 4, p. 817, doi. 10.1007/s00424-014-1542-y
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- Publication type:
- Article
Vascular Reactivity Profile of Novel K<sub>Ca</sub>3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2016, v. 119, n. 2, p. 184, doi. 10.1111/bcpt.12560
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- Publication type:
- Article
Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 25, p. 6848, doi. 10.1093/hmg/ddu408
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- Publication type:
- Article
Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.
- Published in:
- Human Molecular Genetics, 2012, v. 21, n. 25, p. 1, doi. 10.1093/hmg/ddu408
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- Publication type:
- Article
Editorial: Ion Channels and Transporters in Ca<sup>2+</sup> -Dependent Functions of Lymphocytes.
- Published in:
- Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.962110
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- Publication type:
- Article
Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept.
- Published in:
- 2018
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- Publication type:
- journal article
Aflatoxin B 1 Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 12, p. 9938, doi. 10.3390/ijms24129938
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- Publication type:
- Article
The potassium channel Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion.
- Published in:
- Annals of Clinical & Translational Neurology, 2021, v. 8, n. 10, p. 2070, doi. 10.1002/acn3.51456
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- Publication type:
- Article
Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease.
- Published in:
- Annals of Clinical & Translational Neurology, 2019, v. 6, n. 4, p. 723, doi. 10.1002/acn3.754
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- Publication type:
- Article
Targeting potassium channels to treat cerebellar ataxia.
- Published in:
- Annals of Clinical & Translational Neurology, 2018, v. 5, n. 3, p. 297, doi. 10.1002/acn3.527
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- Publication type:
- Article
Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke.
- Published in:
- Annals of Clinical & Translational Neurology, 2018, v. 5, n. 2, p. 147, doi. 10.1002/acn3.513
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- Publication type:
- Article
New capsaicin analogs as molecular rulers to define the permissive conformation of the mouse TRPV1 ligand-binding pocket.
- Published in:
- eLife, 2020, p. 1, doi. 10.7554/eLife.62039
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- Publication type:
- Article
Structural modeling of hERG channel–drug interactions using Rosetta.
- Published in:
- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1244166
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- Publication type:
- Article
Immunocytoprotection after reperfusion with Kv1.3 inhibitors has an extended treatment window for ischemic stroke.
- Published in:
- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1190476
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- Publication type:
- Article
Endothelial KCa channels: Novel targets to reduce atherosclerosis-driven vascular dysfunction.
- Published in:
- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1151244
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- Publication type:
- Article
Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI).
- Published in:
- European Journal of Human Genetics, 2002, v. 10, n. 1, p. 36, doi. 10.1038/sj.ejhg.5200739
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- Publication type:
- Article
The lymphocyte potassium channels Kv1.3 and KCa3.1 as targets for immunosuppression.
- Published in:
- Drug Development Research, 2011, v. 72, n. 7, p. 573, doi. 10.1002/ddr.20467
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- Publication type:
- Article
Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 32, p. 11292, doi. 10.1523/JNEUROSCI.1357-15.2015
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- Publication type:
- Article
Dysregulation of Glutamine Transporter SNAT1 in Rett Syndrome Microglia: A Mechanism for Mitochondrial Dysfunction and Neurotoxicity.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 6, p. 2516, doi. 10.1523/JNEUROSCI.2778-14.2015
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- Publication type:
- Article
O5‐05‐05: REPURPOSING THE KCA3.1 INHIBITOR SENICAPOC AS A MICROGLIA‐TARGETED THERAPEUTIC CANDIDATE FOR ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1656, doi. 10.1016/j.jalz.2018.06.3023
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- Publication type:
- Article
KV1.3 INHIBITION REDUCES AB-INDUCED MICROGLIAL NEUROTOXICITY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P242, doi. 10.1016/j.jalz.2016.06.434
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- Publication type:
- Article
The role of potassium channel Kv1.3 in Aß-induced microglia activation
- Published in:
- 2012
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- Publication type:
- Abstract
Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is K<sub>Ca</sub>3.1-dependent.
- Published in:
- Respiratory Research, 2014, v. 15, n. 12, p. 1, doi. 10.1186/s12931-014-0155-5
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- Publication type:
- Article
Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent.
- Published in:
- 2014
- By:
- Publication type:
- journal article
Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents.
- Published in:
- Annals of the New York Academy of Sciences, 2016, v. 1378, n. 1, p. 124, doi. 10.1111/nyas.13137
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- Publication type:
- Article
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2.
- Published in:
- Archives of Toxicology, 2023, v. 97, n. 5, p. 1355, doi. 10.1007/s00204-023-03475-7
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- Publication type:
- Article
The seizure‐inducing plastic explosive RDX inhibits the α1β2γ2 GABA<sub>A</sub> receptor.
- Published in:
- Annals of Clinical & Translational Neurology, 2022, v. 9, n. 5, p. 600, doi. 10.1002/acn3.51536
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- Publication type:
- Article
Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca<sup>2+</sup>-dependent and regulated by K<sub>Ca</sub>3.1 K<sup>+</sup> channels.
- Published in:
- Fibrogenesis & Tissue Repair, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13069-015-0022-0
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- Publication type:
- Article
The K<sup>+</sup> Channel K<sub>Ca</sub>3.1 as a Novel Target for Idiopathic Pulmonary Fibrosis.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0085244
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- Publication type:
- Article
The Ca<sup>2+</sup>-Activated K<sup>+</sup> Channel KCa3.1 as a Potential New Target for the Prevention of Allograft Vasculopathy.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081006
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- Publication type:
- Article
Blocking KCa3.1 Channels Increases Tumor Cell Killing by a Subpopulation of Human Natural Killer Lymphocytes.
- Published in:
- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076740
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- Publication type:
- Article
K<sub>Ca</sub>3.1 Channel-Blockade Attenuates Airway Pathophysiology in a Sheep Model of Chronic Asthma.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066886
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- Publication type:
- Article
Novel Phenolic Inhibitors of Small/Intermediate-Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels, KCa3.1 and KCa2.3.
- Published in:
- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058614
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- Publication type:
- Article
Genetic KCa3.1-Deficiency Produces Locomotor Hyperactivity and Alterations in Cerebral Monoamine Levels.
- Published in:
- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047744
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- Publication type:
- Article
KCa3.1 potassium channels are critical for cAMP-dependent chloride secretion and cyst growth in autosomal-dominant polycystic kidney disease.
- Published in:
- Kidney International, 2008, v. 74, n. 6, p. 740, doi. 10.1038/ki.2008.246
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- Publication type:
- Article