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A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Published in:
Nature, 2015, v. 522, n. 7556, p. 315, doi. 10.1038/nature14451
By:
- Baragaña, Beatriz;
- Hallyburton, Irene;
- Lee, Marcus C. S.;
- Norcross, Neil R.;
- Grimaldi, Raffaella;
- Otto, Thomas D.;
- Proto, William R.;
- Blagborough, Andrew M.;
- Meister, Stephan;
- Wirjanata, Grennady;
- Ruecker, Andrea;
- Upton, Leanna M.;
- Abraham, Tara S.;
- Almeida, Mariana J.;
- Pradhan, Anupam;
- Porzelle, Achim;
- Martínez, María Santos;
- Bolscher, Judith M.;
- Woodland, Andrew;
- Norval, Suzanne
Publication type:
Article
Screening a protein kinase inhibitor library against Plasmodium falciparum.
Published in:
Malaria Journal, 2017, v. 16, p. 1, doi. 10.1186/s12936-017-2085-4
By:
- Hallyburton, Irene;
- Grimaldi, Raffaella;
- Woodland, Andrew;
- Baragaña, Beatriz;
- Luksch, Torsten;
- Spinks, Daniel;
- James, Daniel;
- Leroy, Didier;
- Waterson, David;
- Fairlamb, Alan H.;
- Wyatt, Paul G.;
- Gilbert, Ian H.;
- Frearson, Julie A.
Publication type:
Article
Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library.
Published in:
ChemMedChem, 2015, v. 10, n. 11, p. 1809, doi. 10.1002/cmdc.201500300
By:
- Woodland, Andrew;
- Thompson, Stephen;
- Cleghorn, Laura A. T.;
- Norcross, Neil;
- De Rycker, Manu;
- Grimaldi, Raffaella;
- Hallyburton, Irene;
- Rao, Bhavya;
- Norval, Suzanne;
- Stojanovski, Laste;
- Brun, Reto;
- Kaiser, Marcel;
- Frearson, Julie A.;
- Gray, David W.;
- Wyatt, Paul G.;
- Read, Kevin D.;
- Gilbert, Ian H.
Publication type:
Article
Back Cover: From On-Target to Off-Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti- Trypanosoma brucei Drug Discovery Lead Molecules (ChemMedChem 7/2013).
Published in:
ChemMedChem, 2013, v. 8, n. 7, p. 1228, doi. 10.1002/cmdc.201390029
By:
- Woodland, Andrew;
- Grimaldi, Raffaella;
- Luksch, Torsten;
- Cleghorn, Laura A. T.;
- Ojo, Kayode K.;
- Van Voorhis, Wesley C.;
- Brenk, Ruth;
- Frearson, Julie A.;
- Gilbert, Ian H.;
- Wyatt, Paul G.
Publication type:
Article
From On-Target to Off-Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti- Trypanosoma brucei Drug Discovery Lead Molecules.
Published in:
ChemMedChem, 2013, v. 8, n. 7, p. 1127, doi. 10.1002/cmdc.201300072
By:
- Woodland, Andrew;
- Grimaldi, Raffaella;
- Luksch, Torsten;
- Cleghorn, Laura A. T.;
- Ojo, Kayode K.;
- Van Voorhis, Wesley C.;
- Brenk, Ruth;
- Frearson, Julie A.;
- Gilbert, Ian H.;
- Wyatt, Paul G.
Publication type:
Article
Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3.
Published in:
ChemMedChem, 2011, v. 6, n. 12, p. 2214, doi. 10.1002/cmdc.201100344
By:
- Cleghorn, Laura A. T.;
- Woodland, Andrew;
- Collie, Iain T.;
- Torrie, Leah S.;
- Norcross, Neil;
- Luksch, Torsten;
- Mpamhanga, Chido;
- Walker, Roderick G.;
- Mottram, Jeremy C.;
- Brenk, Ruth;
- Frearson, Julie A.;
- Gilbert, Ian H.;
- Wyatt, Paul G.
Publication type:
Article
Optimisation of the Anti- Trypanosoma brucei Activity of the Opioid Agonist U50488.
Published in:
ChemMedChem, 2011, v. 6, n. 10, p. 1832, doi. 10.1002/cmdc.201100278
By:
- Smith, Victoria C.;
- Cleghorn, Laura A. T.;
- Woodland, Andrew;
- Spinks, Daniel;
- Hallyburton, Irene;
- Collie, Iain T.;
- Yi Mok, N.;
- Norval, Suzanne;
- Brenk, Ruth;
- Fairlamb, Alan H.;
- Frearson, Julie A.;
- Read, Kevin D.;
- Gilbert, Ian H.;
- Wyatt, Paul G.
Publication type:
Article

Found: 7

A novel multiple-stage antimalarial agent that inhibits protein synthesis.

Screening a protein kinase inhibitor library against Plasmodium falciparum.

Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library.

Back Cover: From On-Target to Off-Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti- Trypanosoma brucei Drug Discovery Lead Molecules (ChemMedChem 7/2013).

From On-Target to Off-Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti- Trypanosoma brucei Drug Discovery Lead Molecules.

Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3.

Optimisation of the Anti- Trypanosoma brucei Activity of the Opioid Agonist U50488.