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Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8<sup>+</sup> T-cell priming to tolerance in autoimmune-prone NOD mice.
- Published in:
- European Journal of Immunology, 2017, v. 47, n. 9, p. 1550, doi. 10.1002/eji.201747089
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- Publication type:
- Article
Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.
- Published in:
- Nature Medicine, 1999, v. 5, n. 9, p. 1026, doi. 10.1038/12465
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- Publication type:
- Article
Altered Systemic and Intestinal IgA Immune Responses in Individuals With Type 1 Diabetes.
- Published in:
- 2020
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- Publication type:
- journal article
Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice.
- Published in:
- 2007
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- Publication type:
- journal article
Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice.
- Published in:
- Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3857, doi. 10.1172/JCI32405
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- Publication type:
- Article
TGF-beta signaling is required for the function of insulin-reactive T regulatory cells.
- Published in:
- 2006
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- Publication type:
- journal article
TGF-ß signaling is required for the function of insulin-reactive T regulatory cells.
- Published in:
- Journal of Clinical Investigation, 2006, v. 116, n. 5, p. 1360, doi. 10.1172/JCI27030
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- Publication type:
- Article
Editorial: Immunopathology of Type 1 Diabetes.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.852963
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- Publication type:
- Article
A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin‐dependent diabetes mellitus in the non‐obese diabetic mouse.
- Published in:
- International Immunology, 2003, v. 15, n. 3, p. 351, doi. 10.1093/intimm/dxg035
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- Publication type:
- Article
Anti-CD20 Treatment Prolongs Syngeneic Islet Graft Survival and Delays the Onset of Recurrent Autoimmune Diabetes.
- Published in:
- Annals of the New York Academy of Sciences, 2008, v. 1150, p. 217, doi. 10.1196/annals.1447.032
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- Publication type:
- Article
IFN-α Can Both Protect against and Promote the Development of Type 1 Diabetes.
- Published in:
- Annals of the New York Academy of Sciences, 2008, v. 1150, p. 187, doi. 10.1196/annals.1447.031
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- Publication type:
- Article
The Role of Toll-Like Receptors 3 and 9 in the Development of Autoimmune Diabetes in NOD Mice.
- Published in:
- Annals of the New York Academy of Sciences, 2008, v. 1150, p. 146, doi. 10.1196/annals.1447.039
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- Publication type:
- Article
Developing a Novel Model System to Target Insulin-Reactive CD8 T Cells.
- Published in:
- Annals of the New York Academy of Sciences, 2008, v. 1150, p. 54, doi. 10.1196/annals.1447.040
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- Publication type:
- Article
Toll-Like Receptors and Diabetes.
- Published in:
- Annals of the New York Academy of Sciences, 2008, v. 1150, p. 123, doi. 10.1196/annals.1447.063
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- Publication type:
- Article
Gene expression profiling in NOD mice reveals that B cells are highly educated by the pancreatic environment during autoimmune diabetes.
- Published in:
- Diabetologia, 2023, v. 66, n. 3, p. 551, doi. 10.1007/s00125-022-05839-7
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- Publication type:
- Article
IgM-associated gut bacteria in obesity and type 2 diabetes in C57BL/6 mice and humans.
- Published in:
- Diabetologia, 2022, v. 65, n. 8, p. 1398, doi. 10.1007/s00125-022-05711-8
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- Publication type:
- Article
Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes.
- Published in:
- Diabetologia, 2022, v. 65, n. 2, p. 343, doi. 10.1007/s00125-021-05595-0
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- Publication type:
- Article
Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype.
- Published in:
- Diabetologia, 2020, v. 63, n. 6, p. 1174, doi. 10.1007/s00125-020-05114-7
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- Publication type:
- Article
Phenotypically distinct anti-insulin B cells repopulate pancreatic islets after anti-CD20 treatment in NOD mice.
- Published in:
- Diabetologia, 2019, v. 62, n. 11, p. 2052, doi. 10.1007/s00125-019-04974-y
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- Publication type:
- Article
Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes.
- Published in:
- Diabetologia, 2018, v. 61, n. 11, p. 2333, doi. 10.1007/s00125-018-4705-0
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- Publication type:
- Article
Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes.
- Published in:
- Diabetologia, 2018, v. 61, n. 8, p. 1794, doi. 10.1007/s00125-018-4651-x
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- Publication type:
- Article
B cell depletion reduces T cell activation in pancreatic islets in a murine autoimmune diabetes model.
- Published in:
- Diabetologia, 2018, v. 61, n. 6, p. 1397, doi. 10.1007/s00125-018-4597-z
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- Publication type:
- Article
Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: the SNAIL study.
- Published in:
- Diabetologia, 2018, v. 61, n. 6, p. 1484, doi. 10.1007/s00125-018-4591-5
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- Publication type:
- Article
Combinatorial detection of autoreactive CD8<sup>+</sup> T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop.
- Published in:
- Diabetologia, 2018, v. 61, n. 3, p. 658, doi. 10.1007/s00125-017-4508-8
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- Publication type:
- Article
Targeted suppression of autoreactive CD8<sup>+</sup> T-cell activation using blocking anti-CD8 antibodies.
- Published in:
- Scientific Reports, 2016, p. 35332, doi. 10.1038/srep35332
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- Publication type:
- Article
Circadian Rhythm Modulation of Microbes During Health and Infection.
- Published in:
- Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.721004
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- Publication type:
- Article
T Cells Recognizing a Peptide Contaminant Undetectable by Mass Spectrometry.
- Published in:
- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0028866
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- Publication type:
- Article
Norovirus Changes Susceptibility to Type 1 Diabetes by Altering Intestinal Microbiota and Immune Cell Functions.
- Published in:
- Frontiers in Immunology, 2019, v. 10, p. 1, doi. 10.3389/fimmu.2019.02654
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- Publication type:
- Article
Gut microbiota and therapy for obesity and type 2 diabetes.
- Published in:
- Frontiers in Endocrinology, 2024, p. 01, doi. 10.3389/fendo.2024.1333778
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- Publication type:
- Article
Hyperglycaemia does not affect antigen-specific activation and cytolytic killing by CD8<sup>+</sup> T cells in vivo.
- Published in:
- Bioscience Reports, 2017, v. 37, n. 4, p. 1, doi. 10.1042/BSR20171079
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- Publication type:
- Article
Hepatitis mouse models: from acute-to-chronic autoimmune hepatitis.
- Published in:
- International Journal of Experimental Pathology, 2014, v. 95, n. 5, p. 309, doi. 10.1111/iep.12090
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- Publication type:
- Article
Innate immunity and intestinal microbiota in the development of Type 1 diabetes.
- Published in:
- Nature, 2008, v. 455, n. 7216, p. 1109, doi. 10.1038/nature07336
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- Publication type:
- Article
Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis.
- Published in:
- Immunological Reviews, 1999, v. 169, n. 1, p. 93, doi. 10.1111/j.1600-065X.1999.tb01309.x
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- Publication type:
- Article
Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans.
- Published in:
- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1276255
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- Publication type:
- Article
Novel engineered B lymphocytes targeting islet-specific T cells inhibit the development of type 1 diabetes in non-obese diabetic Scid mice.
- Published in:
- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1227133
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- Publication type:
- Article
Environmental Determinants of Type 1 Diabetes: From Association to Proving Causality.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.737964
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- Publication type:
- Article
Regulatory B Cells: Role in Type 1 Diabetes.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.746187
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- Publication type:
- Article
IL-10 Deficiency Accelerates Type 1 Diabetes Development via Modulation of Innate and Adaptive Immune Cells and Gut Microbiota in BDC2.5 NOD Mice.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.702955
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- Publication type:
- Article
Inflammasomes and Type 1 Diabetes.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.686956
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- Publication type:
- Article
Insulin-Reactive T Cells Convert Diabetogenic Insulin-Reactive VH125 B Cells Into Tolerogenic Cells by Reducing Germinal Center T:B Cell Interactions in NOD Mice.
- Published in:
- Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.585886
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- Publication type:
- Article
Inhibition of Phosphoinositide 3-Kinase p110delta Does Not Affect T Cell Driven Development of Type 1 Diabetes Despite Significant Effects on Cytokine Production.
- Published in:
- PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146516
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- Publication type:
- Article
B-Cells Promote Intra-Islet CD8<sup>+</sup> Cytotoxic T-Cell Survival to Enhance Type 1 Diabetes.
- Published in:
- Diabetes, 2008, v. 57, n. 4, p. 909, doi. 10.2337/db07-1256
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- Publication type:
- Article
Inhibition of AMP-activated protein kinase protects pancreatic beta-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity.
- Published in:
- 2008
- By:
- Publication type:
- journal article
Inhibition of AMP-Activated Protein Kinase Protects Pancreatic β-Cells From Cytokine-Mediated Apoptosis and CD8<sup>+</sup> T-Cell--Induced Cytotoxicity.
- Published in:
- Diabetes, 2008, v. 57, n. 2, p. 415, doi. 10.2337/db07-0993
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- Publication type:
- Article
The Influence of the Major Histocompatibility Complex on Development of Autoimmune Diabetes in RIP-B7.1 Mice.
- Published in:
- Diabetes, 2005, v. 54, n. 7, p. 2032, doi. 10.2337/diabetes.54.7.2032
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- Publication type:
- Article
Investigation of the role of B-cells in type 1 diabetes in the NOD mouse.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Inhibition of diabetes by an insulin-reactive CD4 T-cell clone in the nonobese diabetic mouse.
- Published in:
- 1997
- By:
- Publication type:
- journal article
Cover Image.
- Published in:
- Diabetes/Metabolism Research & Reviews, 2022, v. 38, n. 1, p. i, doi. 10.1002/dmrr.3518
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- Publication type:
- Article
Innate immunity in latent autoimmune diabetes in adults.
- Published in:
- Diabetes/Metabolism Research & Reviews, 2022, v. 38, n. 1, p. 1, doi. 10.1002/dmrr.3480
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- Publication type:
- Article
Islet‐specific CD8<sup>+</sup> T cells gain effector function in the gut lymphoid tissues via bystander activation not molecular mimicry.
- Published in:
- Immunology & Cell Biology, 2023, v. 101, n. 1, p. 36, doi. 10.1111/imcb.12593
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- Publication type:
- Article