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Crystallization and initial crystallographic analysis of covalent DNA-cleavage complexes of Staphyloccocus aureus DNA gyrase with QPT-1, moxifloxacin and etoposide.
Published in:
Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 10, p. 1242, doi. 10.1107/S2053230X15015290
By:
- Srikannathasan, Velupillai;
- Wohlkonig, Alexandre;
- Shillings, Anthony;
- Singh, Onkar;
- Chan, Pan F.;
- Huang, Jianzhong;
- Gwynn, Michael N.;
- Fosberry, Andrew P.;
- Homes, Paul;
- Hibbs, Martin;
- Theobald, Andrew J.;
- Spitzfaden, Claus;
- Bax, Benjamin D.
Publication type:
Article
Production, crystallization and preliminary X-ray diffraction of the Gαs α-helical domain in complex with a nanobody.
Published in:
Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 11, p. 1504, doi. 10.1107/S2053230X14020962
By:
- Triest, Sarah;
- Wohlkönig, Alexandre;
- Pardon, Els;
- Steyaert, Jan
Publication type:
Article
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands.
Published in:
Nucleic Acids Research, 2012, v. 40, n. 7, p. 3018, doi. 10.1093/nar/gkr1113
By:
- Carette, Xavier;
- Blondiaux, Nicolas;
- Willery, Eve;
- Hoos, Sylviane;
- Lecat-Guillet, Nathalie;
- Lens, Zoé;
- Wohlkönig, Alexandre;
- Wintjens, René;
- Soror, Sameh H.;
- Frénois, Frédéric;
- Dirié, Bertrand;
- Villeret, Vincent;
- England, Patrick;
- Lippens, Guy;
- Deprez, Benoit;
- Locht, Camille;
- Willand, Nicolas;
- Baulard, Alain R.
Publication type:
Article
Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors.
Published in:
Microbial Cell Factories, 2017, v. 16, p. 1, doi. 10.1186/s12934-017-0782-x
By:
- Abskharon, Romany;
- Johnny Dang;
- Elfarash, Ameer;
- Zerui Wang;
- Shen, Pingping;
- Zou, Lewis S.;
- Hassan, Sedky;
- Fei Wang;
- Fujioka, Hisashi;
- Steyaert, Jan;
- Mulaj, Mentor;
- Surewicz, Witold K.;
- Castilla, Joaquín;
- Wohlkonig, Alexandre;
- Wen-Quan Zou
Publication type:
Article
Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance.
Published in:
Nature Structural & Molecular Biology, 2010, v. 17, n. 9, p. 1152, doi. 10.1038/nsmb.1892
By:
- Wohlkonig, Alexandre;
- Chan, Pan F;
- Fosberry, Andrew P;
- Homes, Paul;
- Huang, Jianzhong;
- Kranz, Michael;
- Leydon, Vaughan R;
- Miles, Timothy J;
- Pearson, Neil D;
- Perera, Rajika L;
- Shillings, Anthony J;
- Gwynn, Michael N;
- Bax, Benjamin D
Publication type:
Article
Structural Relationships in the Lysozyme Superfamily: Significant Evidence for Glycoside Hydrolase Signature Motifs.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0015388
By:
- Wohlkönig, Alexandre;
- Huet, Joëlle;
- Looze, Yvan;
- Wintjens, René
Publication type:
Article
Nanobody Loop Mimetics Enhance Son of Sevenless 1‐Catalyzed Nucleotide Exchange on RAS.
Published in:
Angewandte Chemie, 2023, v. 135, n. 24, p. 1, doi. 10.1002/ange.202219095
By:
- Van holsbeeck, Kevin;
- Fischer, Baptiste;
- Gonzalez, Simon;
- Gadais, Charlène;
- Versées, Wim;
- Martins, José C.;
- Martin, Charlotte;
- Wohlkönig, Alexandre;
- Steyaert, Jan;
- Ballet, Steven
Publication type:
Article
Nanobody Loop Mimetics Enhance Son of Sevenless 1‐Catalyzed Nucleotide Exchange on RAS.
Published in:
Angewandte Chemie International Edition, 2023, v. 62, n. 24, p. 1, doi. 10.1002/anie.202219095
By:
- Van holsbeeck, Kevin;
- Fischer, Baptiste;
- Gonzalez, Simon;
- Gadais, Charlène;
- Versées, Wim;
- Martins, José C.;
- Martin, Charlotte;
- Wohlkönig, Alexandre;
- Steyaert, Jan;
- Ballet, Steven
Publication type:
Article
Biphenyl 2,3′,4,5′,6-pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca<sup>2+</sup> responses in rat hepatocytes.
Published in:
FASEB Journal, 2007, v. 21, n. 7, p. 1481, doi. 10.1096/fj.06-7691com
By:
- Vandeput, Fabrice;
- Combettes, Laurent;
- Mills, Stephen J.;
- Backers, Katrien;
- Wohlkönig, Alexandre;
- Parys, Jan B.;
- De Smedt, Humbert;
- Missiaen, Ludwig;
- Dupont, Geneviève;
- Potter, Barry V. L.;
- Erneux, Christophe
Publication type:
Article
Recombinant Human Prion Protein Inhibits Prion Propagation in vitro.
Published in:
Scientific Reports, 2013, p. 1, doi. 10.1038/srep02911
By:
- Jue Yuan;
- Yi-An Zhan;
- Abskharon, Romany;
- Xiangzhu Xiao;
- Martinez, Manuel Camacho;
- Xiaochen Zhou;
- Kneale, Geoff;
- Mikol, Jacqueline;
- Lehmann, Sylvain;
- Surewicz, Witold K.;
- Castilla, Joaquín;
- Steyaert, Jan;
- Shulin Zhang;
- Qingzhong Kong;
- Petersen, Robert B.;
- Wohlkonig, Alexandre;
- Wen-Quan Zou
Publication type:
Article
Methyl arachidonyl fluorophosphonate inhibits Mycobacterium tuberculosis thioesterase TesA and globally affects vancomycin susceptibility.
Published in:
FEBS Letters, 2020, v. 594, n. 1, p. 79, doi. 10.1002/1873-3468.13555
By:
- Yang, Dong;
- Vandenbussche, Guy;
- Vertommen, Didier;
- Evrard, Damien;
- Abskharon, Romany;
- Cavalier, Jean‐François;
- Berger, Gilles;
- Canaan, Stéphane;
- Khan, Mohammad Shahneawz;
- Zeng, Sheng;
- Wohlkönig, Alexandre;
- Prévost, Martine;
- Soumillion, Patrice;
- Fontaine, Véronique
Publication type:
Article
An improved yeast surface display platform for the screening of nanobody immune libraries.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37212-3
By:
- Uchański, Tomasz;
- Zögg, Thomas;
- Yin, Jie;
- Yuan, Daopeng;
- Wohlkönig, Alexandre;
- Fischer, Baptiste;
- Rosenbaum, Daniel M.;
- Kobilka, Brian K.;
- Pardon, Els;
- Steyaert, Jan
Publication type:
Article
A general protocol for the generation of Nanobodies for structural biology.
Published in:
Nature Protocols, 2014, v. 9, n. 3, p. 674, doi. 10.1038/nprot.2014.039
By:
- Pardon, Els;
- Laeremans, Toon;
- Triest, Sarah;
- Rasmussen, Søren G. F.;
- Wohlkönig, Alexandre;
- Ruf, Armin;
- Muyldermans, Serge;
- Hol, Wim G. J.;
- Kobilka, Brian K.;
- Steyaert, Jan
Publication type:
Article
A novel expression system for production of soluble prion proteins in E. coli.
Published in:
Microbial Cell Factories, 2012, v. 11, n. 1, p. 1, doi. 10.1186/1475-2859-11-6
By:
- Ramboarina, Stephanie;
- Hassan, Hassan E. l.;
- Gad, Wael;
- Apostol, Marcin I;
- Giachin, Gabriele;
- Legname, Giuseppe;
- Steyaert, Jan;
- Messens, Joris;
- Soror, Sameh H.;
- Wohlkonig, Alexandre
Publication type:
Article
Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
Published in:
PLoS Pathogens, 2019, v. 15, n. 12, p. 1, doi. 10.1371/journal.ppat.1008139
By:
- Abskharon, Romany;
- Wang, Fei;
- Wohlkonig, Alexandre;
- Ruan, Juxin;
- Soror, Sameh;
- Giachin, Gabriele;
- Pardon, Els;
- Zou, Wenquan;
- Legname, Giuseppe;
- Ma, Jiyan;
- Steyaert, Jan
Publication type:
Article
Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14943-4
By:
- McClelland, Levi J.;
- Zhang, Kaiming;
- Mou, Tung-Chung;
- Johnston, Jake;
- Yates-Hansen, Cindee;
- Li, Shanshan;
- Thomas, Celestine J.;
- Doukov, Tzanko I.;
- Triest, Sarah;
- Wohlkonig, Alexandre;
- Tall, Gregory G.;
- Steyaert, Jan;
- Chiu, Wah;
- Sprang, Stephen R.
Publication type:
Article
Combining in-situ proteolysis and microseed matrix screening to promote crystallization of PrPc-nanobody complexes.
Published in:
PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 9, p. 737, doi. 10.1093/protein/gzr017
By:
- Abskharon, Romany N.N.;
- Soror, Sameh H.;
- Pardon, Els;
- El Hassan, Hassan;
- Legname, Giuseppe;
- Steyaert, Jan;
- Wohlkonig, Alexandre
Publication type:
Article
Characterization of the PAS domain in the sensor-kinase BvgS: mechanical role in signal transmission.
Published in:
BMC Microbiology, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2180-13-172
By:
- Dupré, Elian;
- Wohlkonig, Alexandre;
- Herrou, Julien;
- Locht, Camille;
- Jacob-Dubuisson, Françoise;
- Antoine, Rudy
Publication type:
Article

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