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Novel oncogene amplifications in tumors from a family with Li-Fraumeni syndrome.
- Published in:
- Genes, Chromosomes & Cancer, 2009, v. 48, n. 7, p. 558, doi. 10.1002/gcc.20665
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- Publication type:
- Article
Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma.
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- Genes, Chromosomes & Cancer, 2009, v. 48, n. 3, p. 229, doi. 10.1002/gcc.20635
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- Publication type:
- Article
Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma.
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- Cells (2073-4409), 2021, v. 10, n. 5, p. 1001, doi. 10.3390/cells10051001
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- Publication type:
- Article
HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities.
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- Cells (2073-4409), 2015, v. 4, n. 2, p. 135, doi. 10.3390/cells4020135
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- Publication type:
- Article
Treatment of pediatric patients and young adults with particle therapy at the Heidelberg Ion Therapy Center (HIT): establishment of workflow and initial clinical data.
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- Radiation Oncology, 2012, v. 7, n. 1, p. 170, doi. 10.1186/1748-717X-7-170
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- Publication type:
- Article
Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age - a multicenter retrospective study.
- Published in:
- 2019
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- Publication type:
- journal article
MAPK pathway activation in pilocytic astrocytoma.
- Published in:
- Cellular & Molecular Life Sciences, 2012, v. 69, n. 11, p. 1799, doi. 10.1007/s00018-011-0898-9
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- Article
EFFECTS: an expanded access program of everolimus for patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex.
- Published in:
- 2016
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- Publication type:
- journal article
Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.
- Published in:
- ChemMedChem, 2020, v. 15, n. 13, p. 1163, doi. 10.1002/cmdc.202000149
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- Publication type:
- Article
DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma.
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- PLoS Computational Biology, 2021, v. 17, n. 11, p. 1, doi. 10.1371/journal.pcbi.1009562
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- Article
Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells.
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- Journal of Neuro-Oncology, 2024, v. 166, n. 1, p. 99, doi. 10.1007/s11060-023-04526-w
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- Publication type:
- Article
Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T: evaluation of a modeling workflow.
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- Journal of Neuro-Oncology, 2023, v. 165, n. 3, p. 467, doi. 10.1007/s11060-023-04500-6
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- Publication type:
- Article
Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells.
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- Journal of Neuro-Oncology, 2023, v. 164, n. 3, p. 617, doi. 10.1007/s11060-023-04445-w
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- Publication type:
- Article
Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies.
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- Journal of Neuro-Oncology, 2021, v. 155, n. 2, p. 193, doi. 10.1007/s11060-021-03867-8
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- Publication type:
- Article
Response to trametinib treatment in progressive pediatric low-grade glioma patients.
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- Journal of Neuro-Oncology, 2020, v. 149, n. 3, p. 499, doi. 10.1007/s11060-020-03640-3
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- Publication type:
- Article
HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.
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- Journal of Neuro-Oncology, 2012, v. 110, n. 3, p. 335, doi. 10.1007/s11060-012-0978-1
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- Publication type:
- Article
Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.
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- Acta Neuropathologica, 2023, v. 146, n. 6, p. 853, doi. 10.1007/s00401-023-02638-1
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- Publication type:
- Article
Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.
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- Acta Neuropathologica, 2023, v. 145, n. 1, p. 97, doi. 10.1007/s00401-022-02522-4
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- Publication type:
- Article
Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions.
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- Acta Neuropathologica, 2019, v. 138, n. 5, p. 827, doi. 10.1007/s00401-019-02039-3
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- Article
Risk stratification of childhood medulloblastoma in the molecular era: the current consensus.
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- Acta Neuropathologica, 2016, v. 131, n. 6, p. 821, doi. 10.1007/s00401-016-1569-6
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- Article
Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers.
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- Acta Neuropathologica, 2015, v. 129, n. 5, p. 669, doi. 10.1007/s00401-015-1405-4
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- Publication type:
- Article
MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma.
- Published in:
- Acta Neuropathologica, 2012, v. 123, n. 4, p. 529, doi. 10.1007/s00401-011-0924-x
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- Publication type:
- Article
A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
- Published in:
- Acta Neuropathologica, 2011, v. 122, n. 5, p. 637, doi. 10.1007/s00401-011-0866-3
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- Publication type:
- Article
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.
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- Acta Neuropathologica, 2011, v. 121, n. 6, p. 763, doi. 10.1007/s00401-011-0817-z
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- Publication type:
- Article
Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes.
- Published in:
- Acta Neuropathologica, 2010, v. 120, n. 2, p. 253, doi. 10.1007/s00401-010-0688-8
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- Publication type:
- Article
Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions—A calibration approach.
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- Biometrical Journal, 2019, v. 61, n. 3, p. 488, doi. 10.1002/bimj.201700209
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- Article
Adaptive designs with arbitrary dependence structure.
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- Biometrical Journal, 2014, v. 56, n. 1, p. 86, doi. 10.1002/bimj.201200234
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- Article
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
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- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 121, doi. 10.1186/s40478-015-0201-7
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- Publication type:
- Article
Long-term follow-up of surgical intervention pattern in pediatric low-grade gliomas: report from the German SIOP-LGG 2004 cohort.
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- Journal of Neurosurgery: Pediatrics, 2022, v. 30, n. 3, p. 318, doi. 10.3171/2022.6.PEDS22108
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- Article
Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.
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- British Journal of Cancer, 2024, v. 131, n. 4, p. 763, doi. 10.1038/s41416-024-02740-5
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- Article
Research with Vulnerable People: A Targeted Interdisciplinary Discussion within the Scope of the WMA Declaration of Helsinki Revision.
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- World Medical Journal, 2024, v. 70, n. 1, p. 54
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- Article
ERBB and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein.
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- Molecular Oncology, 2023, v. 17, n. 1, p. 37, doi. 10.1002/1878-0261.13318
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- Article
Overactivation of the IGF signalling pathway in osteosarcoma: a potential therapeutic target?
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- Journal of Pathology: Clinical Research, 2021, v. 7, n. 2, p. 165, doi. 10.1002/cjp2.191
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- Article
NTRK fusions in osteosarcoma are rare and non‐functional events.
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- Journal of Pathology: Clinical Research, 2020, v. 6, n. 2, p. 107, doi. 10.1002/cjp2.158
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- Article
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21247-8
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- Article
Treatment tolerance of particle therapy in pediatric patients.
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- Acta Oncologica, 2015, v. 54, n. 7, p. 1049, doi. 10.3109/0284186X.2014.998273
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- Article
The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies.
- Published in:
- Journal of Pathology, 2021, v. 254, n. 5, p. 556, doi. 10.1002/path.5699
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- Publication type:
- Article
Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors.
- Published in:
- 2021
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- Publication type:
- journal article
Response in a child with a BRAF V600E mutated desmoplastic infantile astrocytoma upon retreatment with vemurafenib.
- Published in:
- 2018
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- Publication type:
- journal article
Hematologic Response to Vorinostat Treatment in Relapsed Myeloid Leukemia of Down Syndrome.
- Published in:
- 2016
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- Publication type:
- journal article
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 8, p. 2649, doi. 10.1007/s00204-018-2234-8
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- Publication type:
- Article
No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients.
- Published in:
- Human Genetics, 2016, v. 135, n. 5, p. 469, doi. 10.1007/s00439-016-1646-x
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- Publication type:
- Article
An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice.
- Published in:
- 2011
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- Publication type:
- journal article
Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma.
- Published in:
- Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac026
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- Publication type:
- Article
Adaption of neurosurgical resection patterns for pediatric low‐grade glioma spanning two decades—Report from the German LGG‐studies 1996–2018.
- Published in:
- Cancer Medicine, 2024, v. 13, n. 12, p. 1, doi. 10.1002/cam4.7417
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- Publication type:
- Article
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 12, p. 6018, doi. 10.1093/nar/gkt346
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- Article
Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.
- Published in:
- Brain Pathology, 2016, v. 26, n. 4, p. 506, doi. 10.1111/bpa.12326
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- Publication type:
- Article
Nestin Expression Identifies Ependymoma Patients with Poor Outcome.
- Published in:
- Brain Pathology, 2012, v. 22, n. 6, p. 848, doi. 10.1111/j.1750-3639.2012.00600.x
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- Publication type:
- Article
Valproic acid treatment of glioblastoma multiforme in a child.
- Published in:
- Pediatric Blood & Cancer, 2004, v. 43, n. 2, p. 181, doi. 10.1002/pbc.20083
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- Publication type:
- Article
Outcome and prognostic factors of desmoplastic medulloblastoma treated within a multidisciplinary treatment concept.
- Published in:
- BMC Cancer, 2010, v. 10, p. 450, doi. 10.1186/1471-2407-10-450
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- Publication type:
- Article