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Communication between subunits within an archaeal clamp-loader complex.
Published in:
EMBO Journal, 2006, v. 25, n. 10, p. 2209, doi. 10.1038/sj.emboj.7601093
By:
- Seybert, Anja;
- Singleton, Martin R.;
- Cook, Nicola;
- Hall, David R.;
- Wigley, Dale B.
Publication type:
Article
Distinct roles for ATP binding and hydrolysis at individual subunits of an archaeal clamp loader.
Published in:
EMBO Journal, 2004, v. 23, n. 6, p. 1360, doi. 10.1038/sj.emboj.7600130
By:
- Seybert, Anja;
- Wigley, Dale B.
Publication type:
Article
Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.
Published in:
EMBO Journal, 2000, v. 19, n. 14, p. 3799, doi. 10.1093/emboj/19.14.3799
By:
- Soultanas, Panos;
- Dillingham, Mark S.;
- Wiley, Paul;
- Webb, Martin R.;
- Wigley, Dale B.
Publication type:
Article
Crystal structure of the site-specific recombinase, XerD.
Published in:
EMBO Journal, 1997, v. 16, n. 17, p. 5178, doi. 10.1093/emboj/16.17.5178
By:
- Subramanya, Hosahalli S.;
- Arciszewska, Lidia K.;
- Baker, Rachel A.;
- Bird, Louise E.;
- Sherratt, David J.;
- Wigley, Dale B.
Publication type:
Article
CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair.
Published in:
eLife, 2019, p. 1, doi. 10.7554/eLife.42129
By:
- Wilkinson, Oliver J.;
- Martín-González, Alejandro;
- Kang, Haejoo;
- Northall, Sarah J;
- Wigley, Dale B.;
- Moreno-Herrero, Fernando;
- Dillingham, Mark Simon
Publication type:
Article
Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.22963
By:
- Wilkinson, Martin;
- Troman, Lucy;
- Nur Ismah, Wan A. K. Wan;
- Chaban, Yuriy;
- Avison, Matthew B.;
- Dillingham, Mark S.;
- Wigley, Dale B.
Publication type:
Article
Mechanism for nuclease regulation in RecBCD.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.18227
By:
- Wilkinson, Martin;
- Chaban, Yuriy;
- Wigley, Dale B.
Publication type:
Article
Functional characterization and architecture of recombinant yeast SWR1 histone exchange complex.
Published in:
Nucleic Acids Research, 2017, v. 45, n. 12, p. 7249, doi. 10.1093/nar/gkx414
By:
- Chia-Liang Lin;
- Chaban, Yuriy;
- Rees, David M.;
- McCormack, Elizabeth A.;
- Ocloo, Lorraine;
- Wigley, Dale B.
Publication type:
Article
The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase.
Published in:
Nucleic Acids Research, 2017, v. 45, n. 7, p. 3875, doi. 10.1093/nar/gkx074
By:
- Sanders, Kelly;
- Chia-Liang Lin;
- Smith, Abigail J.;
- Cronin, Nora;
- Fisher, Gemma;
- Eftychidis, Vasileios;
- McGlynn, Peter;
- Savery, Nigel J.;
- Wigley, Dale B.;
- Dillingham, Mark S.
Publication type:
Article
Synergy and antagonism in regulation of recombinant human INO80 chromatin remodeling complex.
Published in:
Nucleic Acids Research, 2016, v. 44, n. 17, p. 8179, doi. 10.1093/nar/gkw509
By:
- Willhoft, Oliver;
- Bythell-Douglas, Rohan;
- McCormack, Elizabeth A.;
- Wigley, Dale B.
Publication type:
Article
Chi hotspots trigger a conformational change in the helicase-like domain of AddAB to activate homologous recombination.
Published in:
Nucleic Acids Research, 2016, v. 44, n. 6, p. 2727, doi. 10.1093/nar/gkv1543
By:
- Gilhooly, Neville S.;
- Carrasco, Carolina;
- Gollnick, Benjamin;
- Wilkinson, Martin;
- Wigley, Dale B.;
- Moreno-Herrero, Fernando;
- Dillingham, Mark S.
Publication type:
Article
The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins.
Published in:
Nature Structural & Molecular Biology, 2008, v. 15, n. 11, p. 1223, doi. 10.1038/nsmb.1501
By:
- Xiaodong Zhang;
- Wigley, Dale B.
Publication type:
Article
The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin.
Published in:
Proteins, 1997, v. 28, n. 1, p. 41, doi. 10.1002/(SICI)1097-0134(199705)28:1<41::AID-PROT4>3.0.CO;2-M
By:
- Tsai, Francis T.F.;
- Singh, Onkar M.P.;
- Skarzynski, Tadeusz;
- Wonacott, Alan J.;
- Weston, Simon;
- Tucker, Alec;
- Pauptit, Richard A.;
- Breeze, Alexander L.;
- Poyser, J. Philip;
- O'Brien, Ronan;
- Ladbury, John E.;
- Wigley, Dale B.
Publication type:
Article
Site-directed mutagenesis reveals role of mobile arginine residue in lactate dehydrogenase catalysis.
Published in:
Nature, 1986, v. 324, n. 6098, p. 699, doi. 10.1038/324699a0
By:
- Clarke, Anthony R.;
- Wigley, Dale B.;
- Chia, William N.;
- Barstow, David;
- Atkinson, Tony;
- Holbrook, J. John
Publication type:
Article
Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex.
Published in:
EMBO Journal, 2012, v. 31, n. 6, p. 1568, doi. 10.1038/emboj.2012.9
By:
- Saikrishnan, Kayarat;
- Yeeles, Joseph T;
- Gilhooly, Neville S;
- Krajewski, Wojciech W;
- Dillingham, Mark S;
- Wigley, Dale B
Publication type:
Article
DNA binding to RecD: role of the 1B domain in SF1B helicase activity.
Published in:
EMBO Journal, 2008, v. 27, n. 16, p. 2222, doi. 10.1038/emboj.2008.144
By:
- Saikrishnan, Kayarat;
- Griffiths, Stuart P.;
- Cook, Nicola;
- Court, Robert;
- Wigley, Dale B.
Publication type:
Article
Biochemical analysis of components of the pre‐replication complex of Archaeoglobus fulgidus.
Published in:
Nucleic Acids Research, 2003, v. 31, n. 16, p. 4888, doi. 10.1093/nar/gkg662
By:
- Grainge, Ian;
- Scaife, Sarah;
- Wigley, Dale B.
Publication type:
Article
Biochemical characterisation of the clamp/clamp loader proteins from the euryarchaeon Archaeoglobus fulgidus.
Published in:
Nucleic Acids Research, 2002, v. 30, n. 20, p. 4329, doi. 10.1093/nar/gkf584
By:
- Seybert, Anja;
- Scott, David J.;
- Scaife, Sarah;
- Singleton, Martin R.;
- Wigley, Dale B.
Publication type:
Article
Restart of DNA replication in Gram-positive bacteria: functional characterisation of the Bacillus subtilis PriA initiator.
Published in:
Nucleic Acids Research, 2002, v. 30, n. 7, p. 1593, doi. 10.1093/nar/30.7.1593
By:
- Polard, Patrice;
- Marsin, Stéphanie;
- McGovern, Stephen;
- Velten, Marion;
- Wigley, Dale B.;
- Ehrlich, S. Dusko;
- Bruand, Claude
Publication type:
Article
RadA protein from Archaeoglobus fulgidus forms rings, nucleoprotein filaments and catalyses homologous recombination.
Published in:
Nucleic Acids Research, 2001, v. 29, n. 22, p. 4509, doi. 10.1093/nar/29.22.4509
By:
- McIlwraith, Michael J.;
- Hall, David R.;
- Stasiak, Alicja Z.;
- Stasiak, Andrzej;
- Wigley, Dale B.;
- West, Stephen C.
Publication type:
Article
Site-directed mutagenesis of motif III in PcrA helicase reveals a role in coupling ATP hydrolysis to strand separation.
Published in:
Nucleic Acids Research, 1999, v. 27, n. 16, p. 3310, doi. 10.1093/nar/27.16.3310
By:
- Dillingham, Mark S.;
- Soultanas, Panos;
- Wigley, Dale B.;
- Lohman, T.M.;
- Bird, L.E.;
- Wong, I.;
- Iordanescu, S.;
- Subramanya, H.S.;
- Velankar, S.;
- Brosh, R.M.;
- Korolev, S.;
- Story, R.M.;
- Milburn, M.V.;
- Kelley, J.A.;
- Clackson, T.;
- Soultanas, P.;
- Pullman, M.E.;
- Crute, J.J.;
- Bjornson, K.P.;
- Malkov, V.A.
Publication type:
Article
Plasmid replication initiator protein RepD increases the processivity of PcrA DNA helicase.
Published in:
Nucleic Acids Research, 1999, v. 27, n. 6, p. 1421, doi. 10.1093/nar/27.6.1421
By:
- Soultanas, Panos;
- Dillingham, Mark S.;
- Papadopoulos, Fotios;
- Phillips, Simon E. V.;
- Thomas, Chris D.;
- Wigley, Dale B.
Publication type:
Article
Escherichia coli ribosomal protein L3 stimulates the helicase activity of theBacillus stearothermophilus PcrA helicase.
Published in:
Nucleic Acids Research, 1998, v. 26, n. 10, p. 2374, doi. 10.1093/nar/26.10.2374
By:
- Soultanas, Panos;
- Dillingham, Mark S.;
- Wigley, Dale B.
Publication type:
Article
Characterization and crystallization of the helicase domain of bacteriophage T7 gene 4 protein.
Published in:
Nucleic Acids Research, 1997, v. 25, n. 13, p. 2620, doi. 10.1093/nar/25.13.2620
By:
- Bird, Louise E.;
- Håkansson, Kjell;
- Pan, Hu;
- Wigley, Dale B.
Publication type:
Article
Characterization of proteolytic fragments of bacteriophage T7 DNA ligase.
Published in:
Nucleic Acids Research, 1996, v. 24, n. 12, p. 2281, doi. 10.1093/nar/24.12.2281
By:
- Doherty, Aidan J.;
- Ashford, Stephen R.;
- Wigley, Dale B.
Publication type:
Article
Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks.
Published in:
Nature, 2004, v. 432, n. 7014, p. 187, doi. 10.1038/nature02988
By:
- Singleton, Martin R.;
- Dillingham, Mark S.;
- Gaudier, Martin;
- Kowalczykowski, Stephen C.;
- Wigley, Dale B.
Publication type:
Article
Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.83409
By:
- Wilkinson, Martin;
- Wilkinson, Oliver J.;
- Feyerherm, Connie;
- Fletcher, Emma E.;
- Wigley, Dale B.;
- Dillingham, Mark S.
Publication type:
Article
Bacterial DNA repair: recent insights into the mechanism of RecBCD, AddAB and AdnAB.
Published in:
Nature Reviews Microbiology, 2013, v. 11, n. 1, p. 9, doi. 10.1038/nrmicro2917
By:
- Wigley, Dale B.
Publication type:
Article
Structural basis for translocation by AddAB helicase-nuclease and its arrest at χ sites.
Published in:
Nature, 2014, v. 508, n. 7496, p. 416, doi. 10.1038/nature13037
By:
- Krajewski, Wojciech W.;
- Fu, Xin;
- Wilkinson, Martin;
- Cronin, Nora B.;
- Dillingham, Mark S.;
- Wigley, Dale B.
Publication type:
Article

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