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Ion channels as biomarkers of altered myogenesis in myofiber precursors of Duchenne muscular dystrophy.
- Published in:
- Annals of the New York Academy of Sciences, 2024, v. 1534, n. 1, p. 130, doi. 10.1111/nyas.15124
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- Publication type:
- Article
What is the level of dystrophin expression required for effective therapy of Duchenne muscular dystrophy?
- Published in:
- Journal of Muscle Research & Cell Motility, 2019, v. 40, n. 2, p. 141, doi. 10.1007/s10974-019-09535-9
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- Publication type:
- Article
The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development.
- Published in:
- Orphanet Journal of Rare Diseases, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13023-015-0258-1
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- Publication type:
- Article
The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development.
- Published in:
- 2015
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- Publication type:
- journal article
Animal welfare and the 3Rs in European biomedical research.
- Published in:
- Annals of the New York Academy of Sciences, 2011, v. 1245, n. 1, p. 14, doi. 10.1111/j.1749-6632.2011.06335.x
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- Publication type:
- Article
Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function.
- Published in:
- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091221
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- Publication type:
- Article
A New Extensively Characterised Conditionally Immortal Muscle Cell-Line for Investigating Therapeutic Strategies in Muscular Dystrophies.
- Published in:
- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024826
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- Publication type:
- Article
Metformin Treatment Has No Beneficial Effect in a Dose- Response Survival Study in the SOD1<sup>G93A</sup> Mouse Model of ALS and Is Harmful in Female Mice.
- Published in:
- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024189
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- Publication type:
- Article
Transgenic Overexpression of LARGE Induces α-Dystroglycan Hyperglycosylation in Skeletal and Cardiac Muscle.
- Published in:
- PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014434
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- Publication type:
- Article
Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2010, v. 30, n. 4, p. 849, doi. 10.1038/jcbfm.2009.249
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- Publication type:
- Article
In silico characterisation and chromosomal localisation of human RRH (peropsin) -- implications for opsin evolution.
- Published in:
- BMC Genomics, 2003, v. 4, p. 1
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- Publication type:
- Article
Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy.
- Published in:
- PLoS Currents, 2016, p. 243, doi. 10.1371/currents.md.99d88e72634387639707601b237467d7
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- Publication type:
- Article
Identification and Validation of Quantitative PCR Reference Genes Suitable for Normalizing Expression in Normal and Dystrophic Cell Culture Models of Myogenesis.
- Published in:
- PLoS Currents, 2014, p. 262, doi. 10.1371/currents.md.faafdde4bea8df4aa7d06cd5553119a6
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- Publication type:
- Article
Restoration of dystrophin expression using the Sleeping Beauty transposon.
- Published in:
- PLoS Currents, 2011, p. 544, doi. 10.1371/currents.RRN1296
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- Publication type:
- Article
Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamics.
- Published in:
- PLoS ONE, 2020, v. 15, n. 9, p. 1, doi. 10.1371/journal.pone.0239467
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- Publication type:
- Article
Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy.
- Published in:
- Journal of Neuromuscular Diseases, 2021, v. 8, n. 5, p. 845, doi. 10.3233/JND-200524
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- Publication type:
- Article
The human CIC-4 protein, a member of the CLC chloride channel/transporter family, is localized to the endoplasmic reticulum by its N-terminus.
- Published in:
- FASEB Journal, 2006, v. 20, n. 13, p. 2390, doi. 10.1096/fj.05-5588fje
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- Publication type:
- Article
Cmah -dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.
- Published in:
- Human Molecular Genetics, 2019, v. 28, n. 3, p. 396, doi. 10.1093/hmg/ddy346
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- Publication type:
- Article
How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 15, p. 4225, doi. 10.1093/hmg/ddv155
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- Publication type:
- Article
The transgenic expression of LARGE exacerbates the muscle phenotype of dystroglycanopathy mice.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 7, p. 1842, doi. 10.1093/hmg/ddt577
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- Publication type:
- Article
Preventing phosphorylation of dystroglycan ameliorates the dystrophic phenotype in mdx mouse.
- Published in:
- Human Molecular Genetics, 2012, v. 21, n. 20, p. 4508, doi. 10.1093/hmg/dds293
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- Publication type:
- Article
Handling mice using gloves sprayed with alcohol-based hand sanitiser: acute effects on mouse behaviour.
- Published in:
- Animal Technology & Welfare, 2021, v. 20, n. 1, p. 11
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- Publication type:
- Article
Musculoskeletal Geometry, Muscle Architecture and Functional Specialisations of the Mouse Hindlimb.
- Published in:
- PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0147669
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- Publication type:
- Article
Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice.
- Published in:
- Molecular Therapy, 2011, v. 19, n. 2, p. 345, doi. 10.1038/mt.2010.261
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- Publication type:
- Article
Physiological Characterization of Muscle Strength With Variable Levels of Dystrophin Restoration in mdx Mice Following Local Antisense Therapy.
- Published in:
- Molecular Therapy, 2011, v. 19, n. 1, p. 165, doi. 10.1038/mt.2010.213
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- Publication type:
- Article
Codon and mRNA Sequence Optimization of Microdystrophin Transgenes Improves Expression and Physiological Outcome in Dystrophic mdx Mice Following AAV2/8 Gene Transfer.
- Published in:
- Molecular Therapy, 2008, v. 16, n. 11, p. 1825, doi. 10.1038/mt.2008.186
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- Publication type:
- Article
Peptide-Conjugated Antisense Therapy Takes a Skip Ahead.
- Published in:
- 2008
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- Publication type:
- Editorial
38. Morpholino Antisense Oligonucleotide Induced Exon Skipping Efficiently Restores Dystrophin Expression in the mdx Mouse.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S16, doi. 10.1016/j.ymthe.2006.08.051
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- Publication type:
- Article
Designing translationally relevant preclinical studies of new therapeutics.
- Published in:
- Experimental Physiology, 2017, v. 102, n. 6, p. 616, doi. 10.1113/EP086296
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- Publication type:
- Article
Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy.
- Published in:
- Scientific Reports, 2015, p. 11632, doi. 10.1038/srep11632
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- Publication type:
- Article
Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model.
- Published in:
- Journal of Anatomy, 2016, v. 229, n. 4, p. 514, doi. 10.1111/joa.12461
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- Publication type:
- Article
Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo.
- Published in:
- Journal of Cachexia, Sarcopenia & Muscle, 2016, v. 7, n. 4, p. 436, doi. 10.1002/jcsm.12096
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- Publication type:
- Article
FHL1 activates myostatin signalling in skeletal muscle and promotes atrophy.
- Published in:
- FEBS Open Bio, 2015, v. 5, p. 753, doi. 10.1016/j.fob.2015.08.011
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- Publication type:
- Article
Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation.
- Published in:
- Human Molecular Genetics, 2007, v. 16, n. 9, p. 1078, doi. 10.1093/hmg/ddm057
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- Publication type:
- Article
Stable micro-dystrophin gene transfer using an integrating adeno-retroviral hybrid vector ameliorates the dystrophic pathology in mdx mouse muscle.
- Published in:
- Human Molecular Genetics, 2002, v. 11, n. 15, p. 1719, doi. 10.1093/hmg/11.15.1719
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- Publication type:
- Article
Adeno-associated virus vector gene transfer and sarcolemmal expression of a 144 kDa micro-dystrophin effectively restores the dystrophin-associated protein complex and inhibits myofibre degeneration in nude/mdx mice.
- Published in:
- Human Molecular Genetics, 2002, v. 11, n. 7, p. 733, doi. 10.1093/hmg/11.7.733
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- Publication type:
- Article
Identification of qPCR reference genes suitable for normalizing gene expression in the mdx mouse model of Duchenne muscular dystrophy.
- Published in:
- PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0211384
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- Publication type:
- Article
Olfaction variation in mouse husbandry and its implications for refinement and standardization: UK survey of animal scents.
- Published in:
- Laboratory Animals, 2016, v. 50, n. 5, p. 362, doi. 10.1177/0023677215622883
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- Publication type:
- Article
Olfactory variation in mouse husbandry and its implications for refinement and standardization: UK survey of non-animal scents.
- Published in:
- Laboratory Animals, 2016, v. 50, n. 4, p. 286, doi. 10.1177/0023677215614296
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- Publication type:
- Article
The Pen Is Milder Than the Blade: Identification Marking Mice Using Ink on the Tail Appears More Humane Than Ear-Punching Even with Local Anaesthetic.
- Published in:
- Animals (2076-2615), 2021, v. 11, n. 6, p. 1664, doi. 10.3390/ani11061664
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- Publication type:
- Article
Animal Research beyond the Laboratory: Report from a Workshop on Places Other than Licensed Establishments (POLEs) in the UK.
- Published in:
- Animals (2076-2615), 2020, v. 10, n. 10, p. 1868, doi. 10.3390/ani10101868
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- Publication type:
- Article
Characterisation of Expression of mDMAHP, a Homeodomain-Encoding Gene at the Murine DM Locus.
- Published in:
- Human Molecular Genetics, 1997, v. 6, n. 5, p. 651, doi. 10.1093/hmg/6.5.651
- By:
- Publication type:
- Article
Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy.
- Published in:
- Human Molecular Genetics, 1995, v. 4, n. 8, p. 1245
- By:
- Publication type:
- Article
Direct retroviral-mediated transfer of a dystrophin minigene into mdx mouse muscle in vivo.
- Published in:
- Human Molecular Genetics, 1993, v. 2, n. 6, p. 717
- By:
- Publication type:
- Article
Electroporation for Gene Transfer to Skeletal Muscles.
- Published in:
- BioDrugs, 2004, v. 18, n. 3, p. 155, doi. 10.2165/00063030-200418030-00002
- By:
- Publication type:
- Article
Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: Phenotype and loss of spinal cord motor neurons.
- Published in:
- PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0188912
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- Publication type:
- Article