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Nutrient Starvation Decreases Cx43 Levels and Limits Intercellular Communication in Primary Bovine Corneal Endothelial Cells.
Published in:
2016
By:
- D'hondt, Catheleyne;
- Iyyathurai, Jegan;
- Welkenhuyzen, Kirsten;
- Himpens, Bernard;
- Leybaert, Luc;
- Bultynck, Geert
Publication type:
journal article
mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061020
By:
- Decuypere, Jean-Paul;
- Kindt, Dimphny;
- Luyten, Tomas;
- Welkenhuyzen, Kirsten;
- Missiaen, Ludwig;
- De Smedt, Humbert;
- Bultynck, Geert;
- Parys, Jan B.
Publication type:
Article
Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.
Published in:
Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 8, p. 1591, doi. 10.1007/s00424-013-1394-x
By:
- Mekahli, Djalila;
- Decuypere, Jean-Paul;
- Sammels, Eva;
- Welkenhuyzen, Kirsten;
- Schoeber, Joost;
- Audrezet, Marie-Pierre;
- Corvelyn, Anniek;
- Dechênes, Georges;
- Ong, Albert;
- Wilmer, Martijn;
- Heuvel, Lambertus;
- Bultynck, Geert;
- Parys, Jan;
- Missiaen, Ludwig;
- Levtchenko, Elena;
- Smedt, Humbert
Publication type:
Article
Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output.
Published in:
Cellular & Molecular Life Sciences, 2019, v. 76, n. 19, p. 3843, doi. 10.1007/s00018-019-03091-8
By:
- Ivanova, Hristina;
- Wagner II, Larry E.;
- Tanimura, Akihiko;
- Vandermarliere, Elien;
- Luyten, Tomas;
- Welkenhuyzen, Kirsten;
- Alzayady, Kamil J.;
- Wang, Liwei;
- Hamada, Kozo;
- Mikoshiba, Katsuhiko;
- De Smedt, Humbert;
- Martens, Lennart;
- Yule, David I.;
- Parys, Jan B.;
- Bultynck, Geert
Publication type:
Article
A double point mutation at residues Ile14 and Val15 of Bcl‐2 uncovers a role for the BH4 domain in both protein stability and function.
Published in:
FEBS Journal, 2018, v. 285, n. 1, p. 127, doi. 10.1111/febs.14324
By:
- Monaco, Giovanni;
- La Rovere, Rita;
- Karamanou, Spyridoula;
- Welkenhuyzen, Kirsten;
- Ivanova, Hristina;
- Vandermarliere, Elien;
- Di Martile, Marta;
- Del Bufalo, Donatella;
- De Smedt, Humbert;
- Parys, Jan B.;
- Economou, Anastassios;
- Bultynck, Geert
Publication type:
Article
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.
Published in:
Cell Death & Disease, 2023, v. 14, n. 9, p. 1, doi. 10.1038/s41419-023-06120-4
By:
- Sneyers, Flore;
- Kerkhofs, Martijn;
- Speelman-Rooms, Femke;
- Welkenhuyzen, Kirsten;
- La Rovere, Rita;
- Shemy, Ahmed;
- Voet, Arnout;
- Eelen, Guy;
- Dewerchin, Mieke;
- Tait, Stephen W. G.;
- Ghesquière, Bart;
- Bootman, Martin D.;
- Bultynck, Geert
Publication type:
Article
LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner.
Published in:
Cell Death & Disease, 2023, v. 14, n. 7, p. 1, doi. 10.1038/s41419-023-05964-0
By:
- Kania, Elżbieta;
- Long, Jaclyn S.;
- McEwan, David G.;
- Welkenhuyzen, Kirsten;
- La Rovere, Rita;
- Luyten, Tomas;
- Halpin, John;
- Lobbestael, Evy;
- Baekelandt, Veerle;
- Bultynck, Geert;
- Ryan, Kevin M.;
- Parys, Jan B.
Publication type:
Article
The ER Stress Inducer l-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca2+-Dependent Manner.
Published in:
Cells (2073-4409), 2018, v. 7, n. 12, p. 239, doi. 10.3390/cells7120239
By:
- Roest, Gemma;
- Hesemans, Evelien;
- Welkenhuyzen, Kirsten;
- Luyten, Tomas;
- Engedal, Nikolai;
- Bultynck, Geert;
- Parys, Jan B.
Publication type:
Article

Found: 8

Nutrient Starvation Decreases Cx43 Levels and Limits Intercellular Communication in Primary Bovine Corneal Endothelial Cells.

mTOR-Controlled Autophagy Requires Intracellular Ca<sup>2+</sup> Signaling.

Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.

Bcl-2 and IP<sub>3</sub> compete for the ligand-binding domain of IP<sub>3</sub>Rs modulating Ca<sup>2+</sup> signaling output.

A double point mutation at residues Ile14 and Val15 of Bcl‐2 uncovers a role for the BH4 domain in both protein stability and function.

Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.

LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner.

The ER Stress Inducer l-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca2+-Dependent Manner.