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Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09097-w
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- Publication type:
- Article
Repurposing Antimalarial Pyronaridine as a DNA Repair Inhibitor to Exploit the Full Potential of Gold-Nanoparticle-Mediated Radiation Response.
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- Pharmaceutics, 2022, v. 14, n. 12, p. 2795, doi. 10.3390/pharmaceutics14122795
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- Publication type:
- Article
Development of Self-Associating SN-38-Conjugated Poly(ethylene oxide)-Poly(ester) Micelles for Colorectal Cancer Therapy.
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- Pharmaceutics, 2020, v. 12, n. 11, p. 1033, doi. 10.3390/pharmaceutics12111033
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- Publication type:
- Article
Prolonged withdrawal from cocaine self-administration affects prefrontal cortex- and basolateral amygdala-nucleus accumbens core circuits but not accumbens GABAergic local interneurons.
- Published in:
- 2017
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- Publication type:
- journal article
Screening of genotoxicity and mutagenicity in extractable organics from oil sands process-affected water.
- Published in:
- Environmental Toxicology & Chemistry, 2017, v. 36, n. 5, p. 1397, doi. 10.1002/etc.3670
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- Publication type:
- Article
Issue Information.
- Published in:
- Chemical Biology & Drug Design, 2020, v. 95, n. 4, p. i, doi. 10.1111/cbdd.13541
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- Publication type:
- Article
Computer‐aided drug design of small molecule inhibitors of the ERCC1‐XPF protein–protein interaction.
- Published in:
- Chemical Biology & Drug Design, 2020, v. 95, n. 4, p. 460, doi. 10.1111/cbdd.13660
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- Publication type:
- Article
Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV.
- Published in:
- EMBO Journal, 2004, v. 23, n. 19, p. 3874, doi. 10.1038/sj.emboj.7600375
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- Publication type:
- Article
Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols.
- Published in:
- 2002
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- Publication type:
- Correction Notice
Involvement of human polynucleotide kinase in double‐strand break repair by non‐homologous end joining.
- Published in:
- EMBO Journal, 2002, v. 21, n. 11, p. 2827, doi. 10.1093/emboj/21.11.2827
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- Publication type:
- Article
Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining.
- Published in:
- EMBO Journal, 2002, v. 21, n. 11, p. 2827, doi. 10.1093/emboj/21.11.2827
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- Publication type:
- Article
RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 14, p. 3471, doi. 10.3390/ijms20143471
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- Publication type:
- Article
Detection of benzo(a)pyrene diol epoxide-DNA adducts in mononuclear white blood cells by CE immunoassay and its application to studying the effect of glutathione depletion.
- Published in:
- Electrophoresis, 2009, v. 30, n. 9, p. 1558, doi. 10.1002/elps.200800391
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- Publication type:
- Article
Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex.
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- Nucleic Acids Research, 2017, v. 45, n. 10, p. 6238, doi. 10.1093/nar/gkx275
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- Publication type:
- Article
Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. 5, p. 2585, doi. 10.1093/nar/gkw1262
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- Publication type:
- Article
DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 2, p. 875, doi. 10.1093/nar/gku1307
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- Publication type:
- Article
Yields of damage to C4′ deoxyribose and to pyrimidines in pUC18 by the direct effect of ionizing radiation.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 13, p. 6060, doi. 10.1093/nar/gks271
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- Publication type:
- Article
Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 8, p. 3484, doi. 10.1093/nar/gkr1245
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- Publication type:
- Article
Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage.
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- Nucleic Acids Research, 2011, v. 39, n. 21, p. 9224, doi. 10.1093/nar/gkr647
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- Publication type:
- Article
Independent mechanisms of stimulation of polynucleotide kinase/phosphatase by phosphorylated and non-phosphorylated XRCC1.
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- Nucleic Acids Research, 2010, v. 38, n. 2, p. 510
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- Publication type:
- Article
A kinetic model of single-strand annealing for the repair of DNA double-strand breaks.
- Published in:
- Radiation Protection Dosimetry, 2011, v. 143, n. 2-4, p. 191, doi. 10.1093/rpd/ncq535
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- Publication type:
- Article
End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair.
- Published in:
- FEBS Journal, 2005, v. 272, n. 22, p. 5753, doi. 10.1111/j.1742-4658.2005.04962.x
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- Publication type:
- Article
Characterization of the Apoptotic Response Induced by the Cyanine Dye D112: A Potentially Selective Anti-Cancer Compound.
- Published in:
- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0125381
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- Publication type:
- Article
Peak Experiences, Social Interest, and Moral Reasoning: An Exploratory Study.
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- Journal of Individual Psychology, 2002, v. 58, n. 1, p. 35
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- Publication type:
- Article
The Absence of Self in Adlerian Research.
- Published in:
- Journal of Individual Psychology, 1999, v. 55, n. 4, p. 474
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- Publication type:
- Article
Expression of a releasable form of annexin II by human keratinocytes.
- Published in:
- Journal of Cellular Biochemistry, 2002, v. 86, n. 4, p. 737, doi. 10.1002/jcb.10256
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- Publication type:
- Article
Purification and substrate specificity of polydeoxyribonucleotide kinases isolated from calf thymus and rat liver.
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- Journal of Cellular Biochemistry, 1997, v. 64, n. 2, p. 258, doi. 10.1002/(SICI)1097-4644(199702)64:2<258::AID-JCB9>3.0.CO;2-W
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- Publication type:
- Article
Elevation of Cellular BPDE Uptake by Human Cells: A Possible Factor Contributing to Co-Carcinogenicity by Arsenite.
- Published in:
- Environmental Health Perspectives, 2006, v. 114, n. 12, p. 1832, doi. 10.1289/ehp.9284
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- Publication type:
- Article
PNKP is required for maintaining the integrity of progenitor cell populations in adult mice.
- Published in:
- Life Science Alliance, 2021, v. 4, n. 9, p. 1, doi. 10.26508/lsa.202000790
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- Publication type:
- Article
Nano-Delivery of a Novel Inhibitor of Polynucleotide Kinase/Phosphatase (PNKP) for Targeted Sensitization of Colorectal Cancer to Radiation-Induced DNA Damage.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.772920
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- Publication type:
- Article
Repair of DNA strand gaps and nicks containing 3′‐phosphate and 5′‐hydroxyl termini by purified mammalian enzymes.
- Published in:
- Nucleic Acids Research, 1998, v. 26, n. 19, p. 4395
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- Publication type:
- Article
Polybrene/DMSO-assisted gene transfer.
- Published in:
- Molecular Biotechnology, 1994, v. 1, n. 1, p. 29, doi. 10.1007/BF02821509
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- Publication type:
- Article
Innentitelbild: A Sensitive Technique Unravels the Kinetics of Activation and Trans‐Cleavage of CRISPR‐Cas Systems (Angew. Chem. 22/2024).
- Published in:
- Angewandte Chemie, 2024, v. 136, n. 22, p. 1, doi. 10.1002/ange.202407862
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- Publication type:
- Article
A Sensitive Technique Unravels the Kinetics of Activation and Trans‐Cleavage of CRISPR‐Cas Systems.
- Published in:
- Angewandte Chemie, 2024, v. 136, n. 22, p. 1, doi. 10.1002/ange.202404069
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- Publication type:
- Article
Therapeutic and analytical applications of arsenic binding to proteins.
- Published in:
- Metallomics, 2015, v. 7, n. 1, p. 39, doi. 10.1039/c4mt00222a
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- Publication type:
- Article
Inside Cover: A Sensitive Technique Unravels the Kinetics of Activation and Trans‐Cleavage of CRISPR‐Cas Systems (Angew. Chem. Int. Ed. 22/2024).
- Published in:
- Angewandte Chemie International Edition, 2024, v. 63, n. 22, p. 1, doi. 10.1002/anie.202407862
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- Publication type:
- Article
A Sensitive Technique Unravels the Kinetics of Activation and Trans‐Cleavage of CRISPR‐Cas Systems.
- Published in:
- Angewandte Chemie International Edition, 2024, v. 63, n. 22, p. 1, doi. 10.1002/anie.202404069
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- Publication type:
- Article
Identification and characterization of cysteinyl exposure in proteins by selective mercury labeling and nano-electrospray ionization quadrupole time-of-flight mass spectrometry.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2010, v. 24, n. 11, p. 1523, doi. 10.1002/rcm.4550
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- Publication type:
- Article
Benefit of microwave-assisted acid hydrolysis of proteins for mass spectrometric profiling of the human heart tissue proteome.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 16, p. 2779, doi. 10.1002/rcm.3125
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- Publication type:
- Article
Keratinocyte-Releasable Stratifin Functions as a Potent Collagenase-Stimulating Factor in Fibroblasts.
- Published in:
- Journal of Investigative Dermatology, 2004, v. 122, n. 5, p. 1188, doi. 10.1111/j.0022-202X.2004.22519.x
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- Publication type:
- Article
Genetic predisposition to the cytotoxicity of arsenic: the role of DNA damage and ATM.
- Published in:
- FASEB Journal, 2003, v. 17, n. 15, p. 2310, doi. 10.1096/fj.02-0093fje
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- Publication type:
- Article
Attenuation of DNA damage-induced p53 expression by arsenic: A possible mechanism for arsenic co-carcinogenesis.
- Published in:
- Molecular Carcinogenesis, 2008, v. 47, n. 7, p. 508, doi. 10.1002/mc.20406
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- Publication type:
- Article
Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1-XPF-mediated DNA repair.
- Published in:
- 2021
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- Publication type:
- journal article
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1.
- Published in:
- Nature, 2005, v. 434, n. 7029, p. 108, doi. 10.1038/nature03314
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- Publication type:
- Article
Influence of 2-Nitroimidazoles in the Response of FaDu Cells to Ionizing Radiation and Hypoxia/Reoxygenation Stress.
- Published in:
- Antioxidants, 2023, v. 12, n. 2, p. 389, doi. 10.3390/antiox12020389
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- Publication type:
- Article
Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis.
- Published in:
- Cell Death & Disease, 2017, v. 8, n. 2, p. e2587, doi. 10.1038/cddis.2017.19
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- Publication type:
- Article
Clustered DNA Damage and its Complexity: Tracking the History.
- Published in:
- Radiation Research, 2024, v. 202, n. 2, p. 385, doi. 10.1667/RADE-24-00017.1
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- Publication type:
- Article
Characterization of Plasmodium falciparum ATP-dependent DNA helicase RuvB3.
- Published in:
- Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1573-2
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- Publication type:
- Article
Loss of the DNA repair protein, polynucleotide kinase/phosphatase, activates the type 1 interferon response independent of ionizing radiation.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 16, p. 9630, doi. 10.1093/nar/gkae654
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- Publication type:
- Article
Cationic Polymer-Mediated Small Interfering RNA Delivery for P-glycoprotein Down-Regulation in Tumor Cells.
- Published in:
- Cancer (0008543X), 2010, v. 116, n. 23, p. 5544, doi. 10.1002/cncr.25321
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- Publication type:
- Article