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The sirtuin 1/2 inhibitor tenovin-1 induces a nonlinear apoptosis-inducing factor-dependent cell death in a p53 null Ewing’s sarcoma cell line.
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- Investigational New Drugs, 2018, v. 36, n. 3, p. 396, doi. 10.1007/s10637-017-0541-1
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- Article
Poly(ADP-Ribose) Polymerase-1 Lacking Enzymatic Activity Is Not Compatible with Mouse Development.
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- Cells (2073-4409), 2023, v. 12, n. 16, p. 2078, doi. 10.3390/cells12162078
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- Article
The Central Domain of MCPH1 Controls Development of the Cerebral Cortex and Gonads in Mice.
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- Cells (2073-4409), 2022, v. 11, n. 17, p. 2715, doi. 10.3390/cells11172715
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- Article
Oxidative Glucose Metabolism Promotes Senescence in Vascular Endothelial Cells.
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- Cells (2073-4409), 2022, v. 11, n. 14, p. N.PAG, doi. 10.3390/cells11142213
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- Article
Multifaceted Microcephaly-Related Gene MCPH1.
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- Cells (2073-4409), 2022, v. 11, n. 2, p. 275, doi. 10.3390/cells11020275
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- Article
Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis.
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- Cells (2073-4409), 2021, v. 10, n. 12, p. 3365, doi. 10.3390/cells10123365
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- Article
The Enigmatic Function of PARP1: From PARylation Activity to PAR Readers.
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- Cells (2073-4409), 2019, v. 8, n. 12, p. 1625, doi. 10.3390/cells8121625
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- Article
Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool.
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- Oncogene, 2001, v. 20, n. 3, p. 320, doi. 10.1038/sj.onc.1204080
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- Article
Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase.
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- Oncogene, 1997, v. 15, n. 9, p. 1035, doi. 10.1038/sj.onc.1201274
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- Article
C620R mutation of the murine ret proto-oncogene: Loss of function effect in homozygotes and possible gain of function effect in heterozygotes.
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- International Journal of Cancer, 2007, v. 121, n. 2, p. 292, doi. 10.1002/ijc.22378
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- Article
Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice.
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- International Journal of Cancer, 2006, v. 119, n. 4, p. 745, doi. 10.1002/ijc.21890
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- Article
Cooperative treatment effectiveness of ATR and HSP90 inhibition in Ewing's sarcoma cells.
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- Cell & Bioscience, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13578-021-00571-y
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- Article
DNA damage response in neurodevelopment and neuromaintenance.
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- FEBS Journal, 2023, v. 290, n. 13, p. 3300, doi. 10.1111/febs.16535
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- Article
Nbs1‐mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
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- Cell Proliferation, 2021, v. 54, n. 3, p. 1, doi. 10.1111/cpr.12972
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- Article
Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis.
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- Carcinogenesis, 2010, v. 31, n. 12, p. 2058, doi. 10.1093/carcin/bgq205
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- Article
An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability.
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- Human Molecular Genetics, 2004, v. 13, n. 20, p. 2385, doi. 10.1093/hmg/ddh278
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- Article
Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation.
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- Nature Communications, 2013, v. 4, n. 12, p. 2993, doi. 10.1038/ncomms3993
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- Article
Beyond HAT Adaptor: TRRAP Liaisons with Sp1-Mediated Transcription.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12445, doi. 10.3390/ijms222212445
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- Article
The Role of the Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune Memory.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2578, doi. 10.3390/ijms22052578
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- Article
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.
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- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0461-z
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- Article
Highly Effective Work Function Reduction of α‐Borophene via Caesium Decoration: A First‐Principles Investigation.
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- Advanced Theory & Simulations, 2020, v. 3, n. 5, p. 1, doi. 10.1002/adts.201900249
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- Article
Candida albicans β-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages.
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- Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02818
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- Article
Post-Translational Modification of MRE11: Its Implication in DDR and Diseases.
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- Genes, 2021, v. 12, n. 8, p. 1158, doi. 10.3390/genes12081158
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- Article
PARP Determines the Mode of Cell Death in Skin Fibroblasts, but not Keratinocytes, Exposed to Sulfur Mustard.
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- Journal of Investigative Dermatology, 2001, v. 117, n. 6, p. 1566, doi. 10.1046/j.0022-202X.2001.01578.x
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- Article
Microcephaly Gene Mcph1 Deficiency Induces p19ARF-Dependent Cell Cycle Arrest and Senescence.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 9, p. 4597, doi. 10.3390/ijms25094597
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- Article
An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular Senescence.
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- PLoS Genetics, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pgen.1003702
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- Article
Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells.
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- Molecular Oncology, 2021, v. 15, n. 12, p. 3404, doi. 10.1002/1878-0261.13060
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- Article
Differential susceptibility of normal and PARP knock-out mouse fibroblasts to proteasome inhibitors.
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- Journal of Cellular Biochemistry, 2000, v. 78, n. 4, p. 681, doi. 10.1002/1097-4644(20000915)78:4<681::AID-JCB17>3.0.CO;2-D
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- Article
TRIP6 functions in brain ciliogenesis.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26057-6
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- Article
ATR regulates neuronal activity by modulating presynaptic firing.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24217-2
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- Article
Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23580-4
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- Article
RPLP1, a Crucial Ribosomal Protein for Embryonic Development of the Nervous System.
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- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099956
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- Article
PARP-1 Controls Immunosuppressive Function of Regulatory T Cells by Destabilizing Foxp3.
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- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071590
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- Article
Stable murine chondrogenic cell lines derived from c- fos-induced cartilage tumors.
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- Journal of Bone & Mineral Research, 1993, v. 8, n. 7, p. 839, doi. 10.1002/jbmr.5650080710
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- Article
Histone Acetyltransferase Cofactor Trrap Maintains Self-Renewal and Restricts Differentiation of Embryonic Stem Cells.
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- Stem Cells, 2013, v. 31, n. 5, p. 979, doi. 10.1002/stem.1341
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- Article
Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression.
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- Nature Genetics, 2001, v. 29, n. 2, p. 206, doi. 10.1038/ng725
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- Article
Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability.
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- Nature Genetics, 1999, v. 23, n. 1, p. 76, doi. 10.1038/12680
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- Article
Repopulated microglia after pharmacological depletion decrease dendritic spine density in adult mouse brain.
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- Glia, 2024, v. 72, n. 8, p. 1484, doi. 10.1002/glia.24541
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- Article
The protein-tyrosine phosphatase DEP-1 promotes migration and phagocytic activity of microglial cells in part through negative regulation of fyn tyrosine kinase.
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- Glia, 2017, v. 65, n. 2, p. 416, doi. 10.1002/glia.23100
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- Article
Nbn gene inactivation in the CNS of mouse inhibits the myelinating ability of the mature cortical oligodendrocytes.
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- Glia, 2014, v. 62, n. 1, p. 133, doi. 10.1002/glia.22593
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- Article
Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high‐grade gliomas.
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- Neuropathology & Applied Neurobiology, 2023, v. 49, n. 4, p. 1, doi. 10.1111/nan.12915
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- Article
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma.
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- Neuropathology & Applied Neurobiology, 2022, v. 48, n. 6, p. 1, doi. 10.1111/nan.12837
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- Article
MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway.
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- Nature Cell Biology, 2011, v. 13, n. 11, p. 1325, doi. 10.1038/ncb2342
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- Article
Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26982-6
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- Article
The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons.
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- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2021.786199
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- Article
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice.
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- Journal of Clinical Investigation, 2004, v. 114, n. 8, p. 1072
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- Article
Deficiency in mTORC1-controlled C/ EBPβ- mRNA translation improves metabolic health in mice.
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- EMBO Reports, 2015, v. 16, n. 8, p. 1022, doi. 10.15252/embr.201439837
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- Article
The LIM domain protein nTRIP6 modulates the dynamics of myogenic differentiation.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-92331-8
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- Article
NBS1 interacts with Notch signaling in neuronal homeostasis.
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- Nucleic Acids Research, 2020, v. 48, n. 19, p. 10924, doi. 10.1093/nar/gkaa716
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- Article
Progress in the Function and Regulation of ADP-Ribosylation.
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- Science Signaling, 2011, v. 4, n. 174, p. 1, doi. 10.1126/scisignal.2001645
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- Article