Found: 133
Select item for more details and to access through your institution.
How will we know if 11b.hydroxysteroid dehydrogenases are important in common diseases*.
- Published in:
- Clinical Endocrinology, 2000, v. 52, n. 4, p. 401, doi. 10.1046/j.1365-2265.2000.00969.x
- By:
- Publication type:
- Article
Growth hormone replacement inhibits renal and hepatic 11β–hydroxysteroid dehydrogenases in ACTH-deficient patients.
- Published in:
- Clinical Endocrinology, 1998, v. 49, n. 2, p. 257, doi. 10.1046/j.1365-2265.1998.00575.x
- By:
- Publication type:
- Article
Memory deficits in a juvenile rat model of type 1 diabetes are due to excess 11β-HSD1 activity, which is upregulated by high glucose concentrations rather than insulin deficiency.
- Published in:
- Diabetologia, 2023, v. 66, n. 9, p. 1735, doi. 10.1007/s00125-023-05942-3
- By:
- Publication type:
- Article
Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct.
- Published in:
- Diabetes, Obesity & Metabolism, 2017, v. 19, n. 6, p. 883, doi. 10.1111/dom.12899
- By:
- Publication type:
- Article
Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™).
- Published in:
- 2017
- By:
- Publication type:
- journal article
Therapeutic manipulation of glucocorticoid metabolism in cardiovascular disease.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Exploring the Temporal Relation between Body Mass Index and Corticosteroid Metabolite Excretion in Childhood.
- Published in:
- Nutrients, 2020, v. 12, n. 5, p. 1525, doi. 10.3390/nu12051525
- By:
- Publication type:
- Article
Health Behaviours during Pregnancy in Women with Very Severe Obesity.
- Published in:
- Nutrients, 2015, v. 7, n. 10, p. 8431, doi. 10.3390/nu7105403
- By:
- Publication type:
- Article
Partial Deficiency or Short-Term Inhibition of 11 β-Hydroxysteroid Dehydrogenase Type 1 Improves Cognitive Function in Aging Mice.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 41, p. 13867, doi. 10.1523/JNEUROSCI.2783-10.2010
- By:
- Publication type:
- Article
11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis.
- Published in:
- FASEB Journal, 2013, v. 27, n. 4, p. 1519, doi. 10.1096/fj.12-219105
- By:
- Publication type:
- Article
Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice.
- Published in:
- Endocrinology, 2019, v. 160, n. 9, p. 2061, doi. 10.1210/en.2019-00236
- By:
- Publication type:
- Article
Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Tissue Production of Cortisol by 11β-Hydroxysteroid Dehydrogenase Type 1 and Metabolic Disease.
- Published in:
- Annals of the New York Academy of Sciences, 2006, v. 1083, n. 1, p. 165, doi. 10.1196/annals.1367.012
- By:
- Publication type:
- Article
ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.
- Published in:
- Science Translational Medicine, 2016, v. 8, n. 352, p. 1, doi. 10.1126/scitranslmed.aaf9074
- By:
- Publication type:
- Article
5α-Reductase Type 1 Deficiency or Inhibition Predisposes to Insulin Resistance, Hepatic Steatosis, and Liver Fibrosis in Rodents.
- Published in:
- Diabetes, 2015, v. 64, n. 2, p. 447, doi. 10.2337/db14-0249
- By:
- Publication type:
- Article
Recycling Between Cortisol and Cortisone in Human Splanchnic, Subcutaneous Adipose, and Skeletal Muscle Tissues In Vivo.
- Published in:
- Diabetes, 2012, v. 61, n. 6, p. 1357, doi. 10.2337/db11-1345
- By:
- Publication type:
- Article
Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis.
- Published in:
- Diabetes, 2012, v. 61, n. 5, p. 1072, doi. 10.2337/db11-1136
- By:
- Publication type:
- Article
Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization.
- Published in:
- 2012
- By:
- Publication type:
- journal article
Salicylate Downregulates 11β-HSD1 Expression in Adipose Tissue in Obese Mice and in Humans, Mediating Insulin Sensitization.
- Published in:
- Diabetes, 2012, v. 61, n. 4, p. 790, doi. 10.2337/db11-0931
- By:
- Publication type:
- Article
Optimal elevation of β-cell 11β-hydroxysteroid dehydrogenase type 1 is a compensatory mechanism that prevents high-fat diet-induced β-cell failure.
- Published in:
- 2012
- By:
- Publication type:
- journal article
Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism that Prevents High-Fat Diet-Induced β-Cell Failure.
- Published in:
- Diabetes, 2012, v. 61, n. 3, p. 642, doi. 10.2337/db11-1054
- By:
- Publication type:
- Article
Increased whole-body and sustained liver cortisol regeneration by 11beta-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for enzyme inhibition.
- Published in:
- 2011
- By:
- Publication type:
- journal article
Increased Whole-Body and Sustained Liver Cortisol Regeneration by 11β-Hydroxysteroid Dehydrogenase Type 1 in Obese Men With Type 2 Diabetes Provides a Target for Enzyme Inhibition.
- Published in:
- Diabetes, 2011, v. 60, n. 3, p. 720, doi. 10.2337/db10-0726
- By:
- Publication type:
- Article
Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Cortisol Release From Adipose Tissue by 11β-Hydroxysteroid Dehydrogenase Type 1 in Humans.
- Published in:
- Diabetes, 2009, v. 58, n. 1, p. 46, doi. 10.2337/db08-0969
- By:
- Publication type:
- Article
A Choline-Deficient Diet Exacerbates Fatty Liver but Attenuates Insulin Resistance and Glucose Intolerance in Mice Fed a High-Fat Diet.
- Published in:
- 2006
- By:
- Publication type:
- Abstract
The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Identification of human glucocorticoid response markers using integrated multi- omic analysis from a randomized crossover trial.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.62236
- By:
- Publication type:
- Article
Human insulin resistance: the role of glucocorticoids.
- Published in:
- Diabetes, Obesity & Metabolism, 2003, v. 5, n. 1, p. 5, doi. 10.1046/j.1463-1326.2003.00221.x
- By:
- Publication type:
- Article
Diet-induced weight loss alters hepatic glucocorticoid metabolism in type 2 diabetes mellitus.
- Published in:
- European Journal of Endocrinology, 2020, v. 182, n. 4, p. 447, doi. 10.1530/EJE-19-0901
- By:
- Publication type:
- Article
Morning plasma cortisol as a cardiovascular risk factor: findings from prospective cohort and Mendelian randomization studies.
- Published in:
- European Journal of Endocrinology, 2019, v. 181, n. 4, p. 429, doi. 10.1530/EJE-19-0161
- By:
- Publication type:
- Article
Tissue-specific dysregulation of 11β-hydroxysteroid dehydrogenase type 1 in overweight/obese women with polycystic ovary syndrome compared with weight-matched controls.
- Published in:
- European Journal of Endocrinology, 2014, v. 171, n. 1, p. 47, doi. 10.1530/EJE-13-1030
- By:
- Publication type:
- Article
Individual multi-locus heterozygosity is associated with lower morning plasma cortisol concentrations.
- Published in:
- European Journal of Endocrinology, 2013, v. 169, n. 1, p. 59, doi. 10.1530/EJE-12-0916
- By:
- Publication type:
- Article
Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE).
- Published in:
- European Journal of Endocrinology, 2013, v. 168, n. 6, p. 887, doi. 10.1530/EJE-13-0128
- By:
- Publication type:
- Article
Glucocorticoid treatment and impaired mood, memory and metabolism in people with diabetes: the Edinburgh Type 2 Diabetes Study.
- Published in:
- European Journal of Endocrinology, 2012, v. 166, n. 5, p. 861
- By:
- Publication type:
- Article
A combination of polymorphisms in HSD11B1 associates with in vivo 11Β-HSD1 activity and metabolic syndrome in women with and without polycystic ovary syndrome.
- Published in:
- European Journal of Endocrinology, 2011, v. 165, n. 2, p. 283, doi. 10.1530/EJE-11-0091
- By:
- Publication type:
- Article
Glucocorticoids and Cardiovascular Disease.
- Published in:
- European Journal of Endocrinology, 2007, v. 157, n. 5, p. 545, doi. 10.1530/EJE-07-0455
- By:
- Publication type:
- Article
Is there a gender difference in the associations of birthweight and adult hypothalamicpituitaryadrenal axis activity?
- Published in:
- European Journal of Endocrinology, 2005, v. 152, n. 2, p. 249, doi. 10.1530/eje.1.01846
- By:
- Publication type:
- Article
Differential Effects of Abdominal Adipose Tissue Distribution on Insulin Sensitivity in Black and White South African Women.
- Published in:
- Obesity (19307381), 2009, v. 17, n. 8, p. 1506, doi. 10.1038/oby.2009.73
- By:
- Publication type:
- Article
Omental 11ß-hydroxysteroid Dehydrogenase 1 Correlates with Fat Cell Size Independently of Obesity.
- Published in:
- Obesity (19307381), 2007, v. 15, n. 5, p. 1155, doi. 10.1038/oby.2007.618
- By:
- Publication type:
- Article
11β-Hydroxysteroid Dehydrogenase Type 1 in Adipose Tissue and Prospective Changes in Body Weight and Insulin Resistance<sup>*</sup>.
- Published in:
- Obesity (19307381), 2006, v. 14, n. 9, p. 1515, doi. 10.1038/oby.2006.175
- By:
- Publication type:
- Article
Increased A-ring Reduction of Glucocorticoids in Obese Zucker Rats: Effects of Insulin Sensitization<sup>**</sup>.
- Published in:
- Obesity (19307381), 2005, v. 13, n. 9, p. 1523, doi. 10.1038/oby.2005.186
- By:
- Publication type:
- Article
11β-Hydroxysteroid Dehydrogenase Type 1 in Obesity.
- Published in:
- Obesity (19307381), 2004, v. 12, n. 1, p. 1, doi. 10.1038/oby.2004.1
- By:
- Publication type:
- Article
Associations Between CYP17A1 and SERPINA6/A1 Polymorphisms, and Cardiometabolic Risk Factors in Black South Africans.
- Published in:
- Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.687335
- By:
- Publication type:
- Article
Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data.
- Published in:
- American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2018, v. 177, n. 7, p. 641, doi. 10.1002/ajmg.b.32652
- By:
- Publication type:
- Article
Taking Glucocorticoids by Prescription Is Associated with Subsequent Cardiovascular Disease.
- Published in:
- Annals of Internal Medicine, 2004, v. 141, n. 10, p. 764, doi. 10.7326/0003-4819-141-10-200411160-00007
- By:
- Publication type:
- Article
11β-HSD1 inhibition does not affect murine tumour angiogenesis but may exert a selective effect on tumour growth by modulating inflammation and fibrosis.
- Published in:
- PLoS ONE, 2023, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0255709
- By:
- Publication type:
- Article
ECAT-V: where clinical and research training meet.
- Published in:
- Veterinary Record: Journal of the British Veterinary Association, 2013, v. 173, n. 15, p. 364, doi. 10.1136/vr.f6185
- By:
- Publication type:
- Article
XANAMEMTM: A NOVEL 11B-HSD1 INHIBITOR WITH POTENTIAL TO PROVIDE DURABLE SYMPTOMATIC AND DISEASE MODIFYING BENEFITS IN ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1186, doi. 10.1016/j.jalz.2016.07.133
- By:
- Publication type:
- Article