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Total Synthesis of Aspergillomarasmine A and Related Compounds: A Sulfamidate Approach Enables Exploration of Structure-Activity Relationships.
- Published in:
- Angewandte Chemie, 2016, v. 128, n. 42, p. 13453, doi. 10.1002/ange.201606657
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- Publication type:
- Article
Influence of humans on evolution and mobilization of environmental antibiotic resistome.
- Published in:
- 2013
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- Publication type:
- journal article
Back to the future: a new 'old' lead for tuberculosis.
- Published in:
- EMBO Molecular Medicine, 2012, v. 4, n. 10, p. 1029, doi. 10.1002/emmm.201201811
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- Publication type:
- Article
Total Synthesis of Aspergillomarasmine A and Related Compounds: A Sulfamidate Approach Enables Exploration of Structure-Activity Relationships.
- Published in:
- Angewandte Chemie International Edition, 2016, v. 55, n. 42, p. 13259, doi. 10.1002/anie.201606657
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- Publication type:
- Article
Total Synthesis and Activity of the Metallo-β-lactamase Inhibitor Aspergillomarasmine A.
- Published in:
- Angewandte Chemie International Edition, 2016, v. 55, n. 6, p. 2210, doi. 10.1002/anie.201510057
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- Publication type:
- Article
Something old, something new: revisiting natural products in antibiotic drug discovery<sup>1</sup>.
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- Canadian Journal of Microbiology, 2014, v. 60, n. 3, p. 147, doi. 10.1139/cjm-2014-0063
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- Publication type:
- Article
Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance.
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- Biochemical Journal, 2013, v. 454, n. 2, p. 191, doi. 10.1042/BJ20130317
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- Publication type:
- Article
Novel approaches to discovery of antibacterial agents.
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- Animal Health Research Reviews, 2008, v. 9, n. 2, p. 237, doi. 10.1017/S1466252308001527
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- Publication type:
- Article
Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03219-w
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- Publication type:
- Article
Unlocking the potential of natural products in drug discovery.
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- Microbial Biotechnology, 2019, v. 12, n. 1, p. 55, doi. 10.1111/1751-7915.13351
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- Publication type:
- Article
Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics.
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- Nature Biotechnology, 2019, v. 37, n. 10, p. 1149, doi. 10.1038/s41587-019-0241-9
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- Publication type:
- Article
Identifying producers of antibacterial compounds by screening for antibiotic resistance.
- Published in:
- Nature Biotechnology, 2013, v. 31, n. 10, p. 922, doi. 10.1038/nbt.2685
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- Publication type:
- Article
Total Synthesis and Activity of the Metallo-β-lactamase Inhibitor Aspergillomarasmine A.
- Published in:
- Angewandte Chemie, 2016, v. 128, n. 6, p. 2250, doi. 10.1002/ange.201510057
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- Publication type:
- Article
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene ( vanK) required for drug resistance.
- Published in:
- Molecular Microbiology, 2004, v. 52, n. 4, p. 1107, doi. 10.1111/j.1365-2958.2004.04032.x
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- Publication type:
- Article
StoPK-1, a serine/threonine protein kinase from the glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009, affects oxidative stress response.
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- Molecular Microbiology, 2002, v. 44, n. 2, p. 417, doi. 10.1046/j.1365-2958.2002.02879.x
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- Publication type:
- Article
Antibiotic Resistance Is Prevalent in an Isolated Cave Microbiome.
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- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034953
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- Publication type:
- Article
Biosynthesis of the Fluorinated Natural Product Nucleocidin in Streptomyces calvus Is Dependent on the bldA-Specified Leu-tRNA<sup>UUA</sup> Molecule.
- Published in:
- ChemBioChem, 2015, v. 16, n. 17, p. 2498, doi. 10.1002/cbic.201500402
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- Publication type:
- Article
Harnessing the Synthetic Capabilities of Glycopeptide Antibiotic Tailoring Enzymes: Characterization of the UK-68,597 Biosynthetic Cluster.
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- ChemBioChem, 2014, v. 15, n. 17, p. 2613, doi. 10.1002/cbic.201402179
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- Publication type:
- Article
Palmitoyl- dl-Carnitine is a Multitarget Inhibitor of Pseudomonas aeruginosa Biofilm Development.
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- ChemBioChem, 2011, v. 12, n. 18, p. 2759, doi. 10.1002/cbic.201100500
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- Publication type:
- Article
Identification and Characterization of New Inhibitors of Fungal Homoserine Kinase.
- Published in:
- ChemBioChem, 2011, v. 12, n. 8, p. 1179, doi. 10.1002/cbic.201100121
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- Publication type:
- Article
Antibiotic Resistance by Enzyme Inactivation: From Mechanisms to Solutions.
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- ChemBioChem, 2010, v. 11, n. 10, p. 1325, doi. 10.1002/cbic.201000067
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- Publication type:
- Article
Antibiotic resistance is ancient.
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- Nature, 2011, v. 477, n. 7365, p. 457, doi. 10.1038/nature10388
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- Publication type:
- Article
Venturicidin A, A Membrane-active Natural Product Inhibitor of ATP synthase Potentiates Aminoglycoside Antibiotics.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64756-0
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- Publication type:
- Article
Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.
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- Molecular Systems Biology, 2011, v. 7, n. 1, p. 1, doi. 10.1038/msb.2011.31
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- Publication type:
- Article
Dedication: Heinz Floss and Christopher Walsh—pioneers in natural product chemical biology.
- Published in:
- 2019
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- Publication type:
- Editorial
Heterologous expression-facilitated natural products' discovery in actinomycetes.
- Published in:
- Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 3/4, p. 415, doi. 10.1007/s10295-018-2097-2
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- Publication type:
- Article
Capturing the antibiotic resistome of preterm infants reveals new benefits of probiotic supplementation.
- Published in:
- Microbiome, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40168-022-01327-7
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- Publication type:
- Article
Capturing the antibiotic resistome of preterm infants reveals new benefits of probiotic supplementation.
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- Microbiome, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40168-022-01327-7
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- Publication type:
- Article
A diverse intrinsic antibiotic resistome from a cave bacterium.
- Published in:
- Nature Communications, 2016, v. 7, n. 12, p. 13803, doi. 10.1038/ncomms13803
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- Publication type:
- Article
Rifampin phosphotransferase is an unusual antibiotic resistance kinase.
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- Nature Communications, 2016, v. 7, n. 4, p. 11343, doi. 10.1038/ncomms11343
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- Publication type:
- Article
Coronavirus Disease 2019 and Antimicrobial Resistance: Parallel and Interacting Health Emergencies.
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- Clinical Infectious Diseases, 2021, v. 72, n. 9, p. 1657, doi. 10.1093/cid/ciaa773
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- Publication type:
- Article
Antibiotic resistance: it's bad, but why isn't it worse?
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- BMC Biology, 2017, v. 15, p. 1, doi. 10.1186/s12915-017-0423-1
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- Publication type:
- Article
Q&A: Antibiotic resistance: what more do we know and what more can we do?
- Published in:
- 2013
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- Publication type:
- Question & Answer
Q&A: Antibiotic resistance: where does it come from and what can we do about it?
- Published in:
- 2010
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- Publication type:
- Question & Answer
Bacterial proteases, untapped antimicrobial drug targets.
- Published in:
- Journal of Antibiotics, 2017, v. 70, n. 4, p. 366, doi. 10.1038/ja.2016.138
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- Publication type:
- Article
Winners of the 2014 JA Medals for excellence.
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- Journal of Antibiotics, 2015, v. 68, n. 1, p. 1, doi. 10.1038/ja.2014.156
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- Publication type:
- Article
Winners of the 2013 JA Medals for excellence.
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- Journal of Antibiotics, 2014, v. 67, n. 5, p. 351, doi. 10.1038/ja.2014.29
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- Publication type:
- Article
Christopher Walsh: Pioneer and innovator in antibiotic and natural product chemical biology.
- Published in:
- Journal of Antibiotics, 2014, v. 67, n. 1, p. 5, doi. 10.1038/ja.2013.118
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- Publication type:
- Article
First JA Medal goes to a paper on decalpenic acid.
- Published in:
- Journal of Antibiotics, 2012, v. 65, n. 12, p. 591, doi. 10.1038/ja.2012.100
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- Publication type:
- Article
β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents.
- Published in:
- Journal of Antibiotics, 2011, v. 64, n. 7, p. 483, doi. 10.1038/ja.2011.37
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- Publication type:
- Article
Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1.
- Published in:
- Journal of Antibiotics, 2010, v. 63, n. 4, p. 177, doi. 10.1038/ja.2010.13
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- Publication type:
- Article
The tetracycline resistome.
- Published in:
- Cellular & Molecular Life Sciences, 2010, v. 67, n. 3, p. 419, doi. 10.1007/s00018-009-0172-6
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- Publication type:
- Article
Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
- Published in:
- Nature Structural Biology, 2000, v. 7, n. 3, p. 238
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- Publication type:
- Article
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.
- Published in:
- Nature, 2014, v. 510, n. 7506, p. 503, doi. 10.1038/nature13445
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- Publication type:
- Article
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development.
- Published in:
- Genetics, 2020, v. 214, n. 4, p. 1103, doi. 10.1534/genetics.119.302851
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- Publication type:
- Article
The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02680-0
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- Publication type:
- Article
Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase
- Published in:
- FEBS Letters, 2011, v. 585, n. 7, p. 1061, doi. 10.1016/j.febslet.2011.03.012
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- Publication type:
- Article
The antibiotic resistome: the nexus of chemical and genetic diversity.
- Published in:
- Nature Reviews Microbiology, 2007, v. 5, n. 3, p. 175, doi. 10.1038/nrmicro1614
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- Publication type:
- Article
Forces shaping the antibiotic resistome.
- Published in:
- BioEssays, 2014, v. 36, n. 12, p. 1179, doi. 10.1002/bies.201400128
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- Publication type:
- Article
The past, present, and future of antibiotics.
- Published in:
- Science Translational Medicine, 2022, v. 14, n. 657, p. 1, doi. 10.1126/scitranslmed.abo7793
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- Publication type:
- Article