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Non-vitamin K antagonist oral anticoagulants (NOAC): considerations on once- vs. twice-daily regimens and their potential impact on medication adherence.
Published in:
2015
By:
- Heidbuchel, Hein;
- Vrijens, Bernard
Publication type:
commentary
Non-vitamin K antagonistoral anticoagulants (NOAC): considerations on once- vs. twice-daily regimens and their potential impact on medication adherence.
Published in:
EP: Europace, 2015, v. 17, n. 8, p. 1317, doi. 10.1093/europace/euv124
By:
- Heidbuchel, Hein;
- Vrijens, Bernard
Publication type:
Article
Non-vitamin K antagonist oral anticoagulants: considerations on once- vs. twice-daily regimens and their potential impact on medication adherence.
Published in:
EP: Europace, 2015, v. 17, n. 4, p. 514, doi. 10.1093/europace/euu311
By:
- Vrijens, Bernard;
- Heidbuchel, Hein
Publication type:
Article
From monitoring to vigilance about patient adherence to new oral anticoagulants.
Published in:
2014
By:
- Vrijens, Bernard;
- Urquhart, John
Publication type:
Journal Article
From monitoring to vigilance about patient adherence to new oral anticoagulants.
Published in:
EP: Europace, 2014, v. 16, n. 1, p. 149, doi. 10.1093/europace/eut243
By:
- Vrijens, Bernard;
- Urquhart, John
Publication type:
Article
Patient adherence to prescribed antimicrobial drug dosing regimens.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 55, n. 5, p. 616, doi. 10.1093/jac/dki066
By:
- Bernard Vrijens;
- John Urquhart
Publication type:
Article
A structural mean model to allow for noncompliance in a randomized trial comparing 2 active treatments.
Published in:
Biostatistics, 2011, v. 12, n. 2, p. 247, doi. 10.1093/biostatistics/kxq053
By:
- Fischer, Krista;
- Goetghebeur, Els;
- Vrijens, Bernard;
- White, Ian R.
Publication type:
Article
Treatment Adherence and Adherence Patterns of Tofacitinib and Self‐Injectable TNFi Use in People with Rheumatoid Arthritis.
Published in:
ACR Open Rheumatology, 2024, v. 6, n. 2, p. 72, doi. 10.1002/acr2.11622
By:
- Michaud, Kaleb;
- Pedro, Sofia;
- Tousset, Eric;
- Schumacher, Rebecca;
- Agarwal, Ekta;
- Vrijens, Bernard
Publication type:
Article
Analysing breast cancer survivors' acceptance profiles for using an electronic pillbox connected to a smartphone application using Seintinelles, a French community-based research tool.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.889695
By:
- Goetzinger, Catherine;
- Alleaume, Caroline;
- Schritz, Anna;
- Vrijens, Bernard;
- Préau, Marie;
- Fagherazzi, Guy;
- Huiart, Laetitia
Publication type:
Article
Treatment Adherence Intervention Studies in Dermatology and Guidance on How to Support Adherence.
Published in:
American Journal of Clinical Dermatology, 2017, v. 18, n. 2, p. 253, doi. 10.1007/s40257-017-0253-5
By:
- Feldman, Steven;
- Vrijens, Bernard;
- Gieler, Uwe;
- Piaserico, Stefano;
- Puig, Lluís;
- Van De Kerkhof, Peter
Publication type:
Article
Delta T, a Useful Indicator for Pharmacy Dispensing Data to Monitor Medication Adherence.
Published in:
Pharmaceutics, 2022, v. 14, n. 1, p. 103, doi. 10.3390/pharmaceutics14010103
By:
- Baumgartner, Pascal C.;
- Vrijens, Bernard;
- Allemann, Samuel;
- Hersberger, Kurt E.;
- Arnet, Isabelle
Publication type:
Article
Improving antiretroviral therapy adherence in resource-limited settings at scale: a discussion of interventions and recommendations.
Published in:
Journal of the International AIDS Society, 2017, v. 20, p. 1, doi. 10.7448/IAS.20.1.21371
By:
- Haberer, Jessica E.;
- Sabin, Lora;
- Amico, K. Rivet;
- Orrell, Catherine;
- Galárraga, Omar;
- Tsai, Alexander C.;
- Vreeman, Rachel C.;
- Wilson, Ira;
- Sam-Agudu, Nadia A.;
- Blaschke, Terrence F.;
- Vrijens, Bernard;
- Mellins, Claude A.;
- Remien, Robert H.;
- Weiser, Sheri D.;
- Lowenthal, Elizabeth;
- Stirratt, Michael J.;
- Sow, Papa Salif;
- Thomas, Bruce;
- Ford, Nathan;
- Mills, Edward
Publication type:
Article
Improving antiretroviral therapy adherence in resource-limited settings at scale: a discussion of interventions and recommendations.
Published in:
Journal of the International AIDS Society, 2017, v. 20, p. 1, doi. 10.7448/IAS.20.1.21371
By:
- Haberer, Jessica E.;
- Sabin, Lora;
- Rivet Amico, K.;
- Orrell, Catherine;
- Galárraga, Omar;
- Tsai, Alexander C.;
- Vreeman, Rachel C.;
- Wilson, Ira;
- Sam-Agudu, Nadia A.;
- Blaschke, Terrence F.;
- Vrijens, Bernard;
- Mellins, Claude A.;
- Remien, Robert H.;
- Weiser, Sheri D.;
- Lowenthal, Elizabeth;
- Stirratt, Michael J.;
- Salif Sow, Papa;
- Thomas, Bruce;
- Ford, Nathan;
- Mills, Edward
Publication type:
Article
Improving antiretroviral therapy adherence in resource-limited settings at scale: a discussion of interventions and recommendations.
Published in:
Journal of the International AIDS Society, 2017, v. 20, n. 1, p. 1, doi. 10.7448/IAS.20.1.21371
By:
- Haberer, Jessica E.;
- Sabin, Lora;
- Amico, K. Rivet;
- Orrell, Catherine;
- Galárraga, Omar;
- Tsai, Alexander C.;
- Vreeman, Rachel C.;
- Wilson, Ira;
- Sam‐Agudu, Nadia A.;
- Blaschke, Terrence F.;
- Vrijens, Bernard;
- Mellins, Claude A.;
- Remien, Robert H.;
- Weiser, Sheri D.;
- Lowenthal, Elizabeth;
- Stirratt, Michael J.;
- Sow, Papa Salif;
- Thomas, Bruce;
- Ford, Nathan;
- Mills, Edward
Publication type:
Article
Coming full circle in the measurement of medication adherence: opportunities and implications for health care.
Published in:
Patient Preference & Adherence, 2017, v. 11, p. 1009, doi. 10.2147/PPA.S127131
By:
- Buono, Elizabeth Whalley;
- Vrijens, Bernard;
- Bosworth, Hayden B.;
- Liu, Larry Z.;
- Zullig, Leah L.;
- Granger, Bradi B.
Publication type:
Article
Bone turnover markers and bone mineral density response with risedronate therapy: Relationship with fracture risk and patient adherence.
Published in:
Journal of Bone & Mineral Research, 2011, v. 26, n. 7, p. 1662, doi. 10.1002/jbmr.342
By:
- Eastell, Richard;
- Vrijens, Bernard;
- Cahall, David L.;
- Ringe, Johann D.;
- Garnero, Patrick;
- Watts, Nelson B.
Publication type:
Article
Identification and Assessment of Adherence-Enhancing Interventions in Studies Assessing Medication Adherence Through Electronically Compiled Drug Dosing Histories: A Systematic Literature Review and Meta-Analysis.
Published in:
2013
By:
- Demonceau, Jenny;
- Ruppar, Todd;
- Kristanto, Paulus;
- Hughes, Dyfrig;
- Fargher, Emily;
- Kardas, Przemyslaw;
- Geest, Sabina;
- Dobbels, Fabienne;
- Lewek, Pawel;
- Urquhart, John;
- Vrijens, Bernard
Publication type:
Journal Article
Standardized classification and framework for reporting, interpreting, and analysing medication non-adherence in cardiovascular clinical trials: a consensus report from the Non-adherence Academic Research Consortium (NARC).
Published in:
European Heart Journal, 2019, v. 40, n. 25, p. 2070, doi. 10.1093/eurheartj/ehy377
By:
- Valgimigli, Marco;
- Garcia-Garcia, Hector M;
- Vrijens, Bernard;
- Vranckx, Pascal;
- McFadden, Eugène P;
- Costa, Francesco;
- Pieper, Karen;
- Vock, David M;
- Zhang, Min;
- Es, Gerrit-Anne Van;
- Tricoci, Pierluigi;
- Baber, Usman;
- Steg, Gabriel;
- Montalescot, Gilles;
- Angiolillo, Dominick J;
- Serruys, Patrick W;
- Farb, Andrew;
- Windecker, Stephan;
- Kastrati, Adnan;
- Colombo, Antonio
Publication type:
Article
Immunosuppressive therapy after solid-organ transplantation: does the INTERMED identify patients at risk of poor adherence?
Published in:
Pharmacy Practice (1886-3655), 2016, v. 14, n. 4, p. 1, doi. 10.18549/PharmPract.2016.04.822
By:
- MICHAUD, Laurent;
- LUDWIG, Gundula;
- BERNEY, Sylvie;
- RODRIGUES, Stéphanie;
- NIQUILLE, Anne;
- SANTSCHI, Valérie;
- FAVRE, Anne-Sophie;
- LANGE, Anne-Catherine;
- MICHELS, Annemieke A.;
- VRIJENS, Bernard;
- BUGNON, Olivier;
- PILON, Nathalie;
- PASCUAL, Manuel;
- VENETZ, Jean-Pierre;
- STIEFEL, Friedrich;
- SCHNEIDER, Marie-Paule
Publication type:
Article
Decreased Adherence to Antiretroviral Therapy Observed prior to Transient Human Immunodeficiency Virus Type 1 Viremia.
Published in:
Journal of Infectious Diseases, 2007, v. 196, n. 12, p. 1773, doi. 10.1086/523704
By:
- Podsadecki, Thomas J.;
- Vrijens, Bernard C.;
- Tousset, Eric P.;
- Rode, Richard A.;
- Hanna, George J.
Publication type:
Article
Effect of Monitoring Bone Turnover Markers on Persistence with Risedronate Treatment of Postmenopausal Osteoporosis.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2007, v. 92, n. 4, p. 1296, doi. 10.1210/jc.2006-1526
By:
- Delmas, Pierre D.;
- Vrijens, Bernard;
- Eastell, Richard;
- Roux, Christian;
- Pols, Huibert A. P.;
- Ringe, Johann D.;
- Grauer, Andreas;
- Cahall, David;
- Watts, Nelson B.
Publication type:
Article
Persistence as a Robust Indicator of Medication Adherence-Related Quality and Performance.
Published in:
International Journal of Environmental Research & Public Health, 2021, v. 18, n. 9, p. 4872, doi. 10.3390/ijerph18094872
By:
- Menditto, Enrica;
- Cahir, Caitriona;
- Malo, Sara;
- Aguilar-Palacio, Isabel;
- Almada, Marta;
- Costa, Elisio;
- Giardini, Anna;
- Gil Peinado, María;
- Massot Mesquida, Mireia;
- Mucherino, Sara;
- Orlando, Valentina;
- Parra-Calderón, Carlos Luis;
- Pepiol Salom, Enrique;
- Kardas, Przemyslaw;
- Vrijens, Bernard;
- Tchounwou, Paul B.
Publication type:
Article
Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria.
Published in:
Wiener Klinische Wochenschrift, 2015, v. 127, n. 9/10, p. 379, doi. 10.1007/s00508-015-0782-y
By:
- Lötsch, Felix;
- Auer-Hackenberg, Lorenz;
- Groger, Mirjam;
- Rehman, Khalid;
- Morrison, Valerie;
- Holmes, Emily;
- Parveen, Sahdia;
- Plumpton, Catrin;
- Clyne, Wendy;
- Geest, Sabina;
- Dobbels, Fabienne;
- Vrijens, Bernard;
- Kardas, Przemyslaw;
- Hughes, Dyfrig;
- Ramharter, Michael
Publication type:
Article
The impacts of undetected nonadherence in phase II, III and post‐marketing clinical trials: An overview.
Published in:
British Journal of Clinical Pharmacology, 2024, v. 90, n. 8, p. 1984, doi. 10.1111/bcp.16089
By:
- Le Flohic, Elise;
- Vrijens, Bernard;
- Hiligsmann, Mickaël
Publication type:
Article
A framework for understanding sources of bias in medication adherence research.
Published in:
British Journal of Clinical Pharmacology, 2023, v. 89, n. 11, p. 3444, doi. 10.1111/bcp.15863
By:
- Sinnappah, Klarissa A.;
- Hughes, Dyfrig A.;
- Stocker, Sophie L.;
- Vrijens, Bernard;
- Aronson, Jeffrey K.;
- Wright, Daniel F. B.
Publication type:
Article
Methodological considerations on estimating medication adherence from self‐report, electronic monitoring and electronic healthcare databases using the TEOS framework.
Published in:
British Journal of Clinical Pharmacology, 2023, v. 89, n. 7, p. 1918, doi. 10.1111/bcp.15375
By:
- Dima, Alexandra L.;
- Allemann, Samuel S.;
- Dunbar‐Jacob, Jacqueline;
- Hughes, Dyfrig A.;
- Vrijens, Bernard;
- Wilson, Ira B.
Publication type:
Article
TEOS: A framework for constructing operational definitions of medication adherence based on Timelines–Events–Objectives–Sources.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 6, p. 2521, doi. 10.1111/bcp.14659
By:
- Dima, Alexandra L.;
- Allemann, Samuel S.;
- Dunbar‐Jacob, Jacqueline;
- Hughes, Dyfrig A.;
- Vrijens, Bernard;
- Wilson, Ira B.
Publication type:
Article
Measuring and reporting treatment adherence: What can we learn by comparing two respiratory conditions?
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 3, p. 825, doi. 10.1111/bcp.14458
By:
- Tibble, Holly;
- Flook, Mary;
- Sheikh, Aziz;
- Tsanas, Athanasios;
- Horne, Rob;
- Vrijens, Bernard;
- De Geest, Sabina;
- Stagg, Helen R.
Publication type:
Article
How the EMERGE guideline on medication adherence can improve the quality of clinical trials.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 4, p. 687, doi. 10.1111/bcp.14240
By:
- Eliasson, Lina;
- Clifford, Sarah;
- Mulick, Amy;
- Jackson, Christina;
- Vrijens, Bernard
Publication type:
Article
The ABC taxonomy for medication adherence translated into French and German.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 4, p. 734, doi. 10.1111/bcp.14172
By:
- Haag, Melanie;
- Lehmann, Audrey;
- Hersberger, Kurt E.;
- Schneider, Marie‐Paule;
- Gauchet, Aurélie;
- Vrijens, Bernard;
- Arnet, Isabelle;
- Allenet, Benoît
Publication type:
Article
A Six Sigma framework to successfully manage medication adherence.
Published in:
British Journal of Clinical Pharmacology, 2019, v. 85, n. 8, p. 1661, doi. 10.1111/bcp.13905
By:
- Vrijens, Bernard
Publication type:
Article
Effect of long-term adherence to clopidogrel on the VASP-PRI after elective coronary stent implantation: a randomized controlled study.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 82, n. 6, p. 1486, doi. 10.1111/bcp.13071
By:
- Forni Ogna, Valentina;
- Menetrey, Isabelle;
- Muller, Olivier;
- Tousset, Eric;
- Guihard, Linda;
- Fontana, Pierre;
- Eeckhout, Eric;
- Eap, Chin B.;
- Vrijens, Bernard;
- Burnier, Michel;
- Wuerzner, Grégoire
Publication type:
Article
A scoping review of studies comparing the medication event monitoring system (MEMS) with alternative methods for measuring medication adherence.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 82, n. 1, p. 268, doi. 10.1111/bcp.12942
By:
- El Alili, Mohamed;
- Vrijens, Bernard;
- Demonceau, Jenny;
- Evers, Silvia M.;
- Hiligsmann, Mickael
Publication type:
Article
Projected inhibition of platelet aggregation with ticagrelor twice daily vs. clopidogrel once daily based on patient adherence data (the TWICE project).
Published in:
British Journal of Clinical Pharmacology, 2014, v. 77, n. 5, p. 746, doi. 10.1111/bcp.12275
By:
- Vrijens, Bernard;
- Claeys, Marc J.;
- Legrand, Victor;
- Vandendriessche, Eef;
- Van de Werf, Frans
Publication type:
Article
A new taxonomy for describing and defining adherence to medications.
Published in:
British Journal of Clinical Pharmacology, 2012, v. 73, n. 5, p. 691, doi. 10.1111/j.1365-2125.2012.04167.x
By:
- Vrijens, Bernard;
- De Geest, Sabina;
- Hughes, Dyfrig A.;
- Przemyslaw, Kardas;
- Demonceau, Jenny;
- Ruppar, Todd;
- Dobbels, Fabienne;
- Fargher, Emily;
- Morrison, Valerie;
- Lewek, Pawel;
- Matyjaszczyk, Michal;
- Mshelia, Comfort;
- Clyne, Wendy;
- Aronson, Jeffrey K.;
- Urquhart, J.
Publication type:
Article
Analysis and Interpretation of 24-h Blood Pressure Profiles: Appropriate Mathematical Models May Yield Deeper Understanding.
Published in:
2008
By:
- Parati, Gianfranco;
- Vrijens, Bernard;
- Vincze, Gábor
Publication type:
Editorial
The Need to Develop Standard Measures of Patient Adherence for Big Data: Viewpoint.
Published in:
2020
By:
- Kardas, Przemyslaw;
- Aguilar-Palacio, Isabel;
- Almada, Marta;
- Cahir, Caitriona;
- Costa, Elisio;
- Giardini, Anna;
- Malo, Sara;
- Mesquida, Mireia Massot;
- Menditto, Enrica;
- Midão, Luís;
- Parra-Calderón, Carlos Luis;
- Salom, Enrique Pepiol;
- Vrijens, Bernard;
- Costa, Elísio;
- Massot Mesquida, Mireia;
- Midão, Luis;
- Pepiol Salom, Enrique
Publication type:
journal article
Improving medication adherence research reporting: ESPACOMP Medication Adherence Reporting Guideline (EMERGE).
Published in:
European Journal of Cardiovascular Nursing, 2019, v. 18, n. 4, p. 258, doi. 10.1177/1474515119830298
By:
- De Geest, Sabina;
- Zullig, Leah L.;
- Dunbar-Jacob, Jacqueline;
- Hughes, Dyfrig;
- Wilson, Ira B.;
- Vrijens, Bernard
Publication type:
Article
Does co-payment for inhaler devices affect therapy adherence and disease outcomes? A historical, matched cohort study.
Published in:
Pragmatic & Observational Research, 2017, v. 8, p. 31, doi. 10.2147/POR.S132658
By:
- Voorham, Jaco;
- Vrijens, Bernard;
- van Boven, Job F. M.;
- Ryan, Dermot;
- Miravitlles, Marc;
- Law, Lisa M.;
- Price, David B.
Publication type:
Article
Adherence to HAART therapy measured by electronic monitoring in newly diagnosed HIV patients in Botswana.
Published in:
European Journal of Clinical Pharmacology, 2007, v. 63, n. 12, p. 1115, doi. 10.1007/s00228-007-0369-2
By:
- Vriesendorp, Reinout;
- Cohen, Adam;
- Kristanto, Paulus;
- Vrijens, Bernard;
- Rakesh, Pande;
- Anand, Bene;
- Iwebor, Henry Uchechukwaka;
- Stiekema, Jacobus
Publication type:
Article
Real‐World Adherence to Oral Methotrexate Measured Electronically in Patients With Established Rheumatoid Arthritis.
Published in:
ACR Open Rheumatology, 2019, v. 1, n. 9, p. 560, doi. 10.1002/acr2.11079
By:
- Michaud, Kaleb;
- Vrijens, Bernard;
- Tousset, Eric;
- Pedro, Sofia;
- Schumacher, Rebecca;
- Dasic, Gorana;
- Chen, Connie;
- Agarwal, Ekta;
- Suarez‐Almazor, Maria E.
Publication type:
Article
The Odds that Clinically Unrecognized Poor or Partial Adherence Confuses Population Pharmacokinetic/Pharmacodynamic Analyses.
Published in:
Basic & Clinical Pharmacology & Toxicology, 2005, v. 96, n. 3, p. 225, doi. 10.1111/j.1742-7843.2005.pto960312.x
By:
- Vrijens, Bernard;
- Gross, Robert;
- Urquhart, John
Publication type:
Article
'Hedged' prescribing for partially compliant patients.
Published in:
2006
By:
- Urquhart, John;
- Vrijens, Bernard
Publication type:
journal article
Successful Projection of the Time Course of Drug Concentration in Plasma During a 1-Year Period From Electronically Compiled Dosing-Time Data Used as Input to Individually Parameterized Pharmacokinetic Models.
Published in:
Journal of Clinical Pharmacology, 2005, v. 45, n. 4, p. 461, doi. 10.1177/0091270004274433
By:
- Vrijens, Bernard;
- Tousset, Eric;
- Rode, Richard;
- Bertz, Richard;
- Mayer, Steve;
- Urquhart, John
Publication type:
Article
Modelling the association between adherence and viral load in HIV-infected patients.
Published in:
Statistics in Medicine, 2005, v. 24, n. 17, p. 2719, doi. 10.1002/sim.2130
By:
- Vrijens, Bernard;
- Goetghebeur, Els;
- de Klerk, Erik;
- Rode, Richard;
- Mayer, Steve;
- Urquhart, John
Publication type:
Article
Electronic monitoring of variation in drug intakes can reduce bias and improve precision in pharmacokinetic/pharmacodynamic population studies.
Published in:
Statistics in Medicine, 2004, v. 23, n. 4, p. 531, doi. 10.1002/sim.1619
By:
- Bernard Vrijens;
- Els Goetghebeur
Publication type:
Article
Effect of intervention through a pharmaceutical care program on patient adherence with prescribed once-daily atorvastatin.
Published in:
Pharmacoepidemiology & Drug Safety, 2006, v. 15, n. 2, p. 115, doi. 10.1002/pds.1198
By:
- Vrijens, Bernard;
- Belmans, Ann;
- Matthys, Katelijne;
- Klerk, Erik de;
- Lesaffre, Emmanuel
Publication type:
Article
Comparative Long-Term Effect of Three Anti-P2Y12 Drugs after Percutaneous Angioplasty: An Observational Study Based on Electronic Drug Adherence Monitoring.
Published in:
Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00738
By:
- Ogna, Valentina Forni;
- Bassi, Isabelle;
- Menetrey, Isabelle;
- Muller, Olivier;
- Tousset, Eric;
- Fontana, Pierre;
- Eeckhout, Eric;
- Eap, Chin B.;
- Vrijens, Bernard;
- Burnier, Michel;
- Wuerzner, Grégoire
Publication type:
Article
Current Situation of Medication Adherence in Hypertension.
Published in:
Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00100
By:
- Vrijens, Bernard;
- Antoniou, Sotiris;
- Burnier, Michel;
- de la Sierra, Alejandro;
- Volpe, Massimo
Publication type:
Article
Evaluating Objective Metrics of habit strength for taking medications.
Published in:
Journal of Behavioral Medicine, 2023, v. 46, n. 4, p. 632, doi. 10.1007/s10865-023-00392-z
By:
- Phillips, L. Alison;
- Pironet, Antoine;
- Vrijens, Bernard
Publication type:
Article

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