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A Phase 1 Randomized, Double‐Blind, Placebo‐Controlled Trial to Assess the Safety, Tolerability, and Pharmacokinetics of a Respiratory Syncytial Virus Neutralizing Monoclonal Antibody MK‐1654 in Healthy Adults.
Published in:
Clinical Pharmacology in Drug Development, 2021, v. 10, n. 5, p. 556, doi. 10.1002/cpdd.883
By:
- Aliprantis, Antonios O.;
- Wolford, Dennis;
- Caro, Luzelena;
- Maas, Brian M.;
- Ma, Hua;
- Montgomery, Diana L.;
- Sterling, Laura M.;
- Hunt, Allen;
- Cox, Kara S.;
- Vora, Kalpit A.;
- Roadcap, Brad A.;
- Railkar, Radha A.;
- Lee, Andrew W.;
- Stoch, S. Aubrey;
- Lai, Eseng
Publication type:
Article
Identification and Quantification of a Pneumococcal Cell Wall Polysaccharide by Antibody-Enhanced Chromatography Assay.
Published in:
Vaccines, 2024, v. 12, n. 5, p. 469, doi. 10.3390/vaccines12050469
By:
- Deng, James Z.;
- Chen, Zhifeng;
- Small, James;
- Yuan, Yue;
- Cox, Kara;
- Tang, Aimin;
- Roman, Jeanette;
- Guan, Liming;
- Feller, Katrina;
- Ansbro, Frances;
- Vora, Kalpit
Publication type:
Article
Profiling of hMPV F-specific antibodies isolated from human memory B cells.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30205-x
By:
- Xiao, Xiao;
- Fridman, Arthur;
- Zhang, Lu;
- Pristatsky, Pavlo;
- Durr, Eberhard;
- Minnier, Michael;
- Tang, Aimin;
- Cox, Kara S.;
- Wen, Zhiyun;
- Moore, Renee;
- Tian, Dongrui;
- Galli, Jennifer D.;
- Cosmi, Scott;
- Eddins, Michael J.;
- Sullivan, Nicole L.;
- Yan, Xiaodong;
- Bett, Andrew J.;
- Su, Hua-Poo;
- Vora, Kalpit A.;
- Chen, Zhifeng
Publication type:
Article
Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response.
Published in:
2018
By:
- Chen, Zhifeng;
- Cox, Kara S.;
- Tang, Aimin;
- Roman, Jeanette;
- Fink, Malorie;
- Kaufhold, Robin M.;
- Guan, Liming;
- Xie, Andy;
- Boddicker, Melissa A.;
- Mcguinness, Debra;
- Xiao, Xiao;
- Li, Hualin;
- Skinner, Julie M.;
- Verch, Thorsten;
- Retzlaff, Mary;
- Vora, Kalpit A.
Publication type:
journal article
Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses.
Published in:
BMC Immunology, 2009, v. 10, p. 1, doi. 10.1186/1471-2172-10-19
By:
- Vora, Kalpit A.;
- Porter, Gene;
- Peng, Roche;
- Yan Cui;
- Pryor, Kellyann;
- Eiermann, George;
- Zaller, Dennis M.
Publication type:
Article
Neutralization Activity of Anti-drug Antibodies Against a Biotherapeutic Can Be Predicted from a Comprehensive Pharmacokinetics, Pharmacodynamics, and Anti-drug Antibody Data Analysis.
Published in:
AAPS Journal, 2022, v. 24, n. 6, p. 1, doi. 10.1208/s12248-022-00753-7
By:
- Xu, Weifeng;
- Maas, Brian;
- Roadcap, Brad;
- Swarup, Aparna;
- Steinmetz, Thomas;
- Luo, Linlin;
- Ichetovkin, Marina;
- Wood, Sandra;
- Vazvaei-Smith, Faye;
- Lee, Andrew Wen-Tseng;
- Vora, Kalpit;
- Helmy, Roy
Publication type:
Article
Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes.
Published in:
PLoS Pathogens, 2019, v. 15, n. 6, p. 1, doi. 10.1371/journal.ppat.1007716
By:
- Li, Leike;
- Meng, Weixu;
- Horton, Melanie;
- DiStefano, Daniel R.;
- Thoryk, Elizabeth A.;
- Pfaff, Jennifer M.;
- Wang, Qihui;
- Salazar, Georgina T.;
- Barnes, Trevor;
- Doranz, Benjamin J.;
- Bett, Andrew J.;
- Casimiro, Danilo R.;
- Vora, Kalpit A.;
- An, Zhiqiang;
- Zhang, Ningyan
Publication type:
Article
The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment.
Published in:
Immunological Reviews, 1998, v. 162, n. 1, p. 183, doi. 10.1111/j.1600-065X.1998.tb01441.x
By:
- Manser, Tim;
- Tumas-Brundage, Kathleen M.;
- Casson, Lawrence P.;
- Giusti, Angela M.;
- Hande, Shailaja;
- Notidis, Evangelia;
- Vora, Kalpit A.
Publication type:
Article
Development and Characterization of Monoclonal Antibodies to Staphylococcus aureus Capsule Type 5.
Published in:
FASEB Journal, 2008, v. 22, p. 669, doi. 10.1096/fasebj.22.2_supplement.669
By:
- Fan, Hongxia;
- Brown, Martha;
- Kowalski, Rose;
- Cook, James;
- Kary, Marcia;
- Hepler, Robert;
- Secore, Susan;
- Zorman, Julie;
- Pancari, Gregory;
- Vora, Kalpit;
- Cope, Leslie;
- Caulfield, Michael;
- McNeely, Tessie
Publication type:
Article
Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein.
Published in:
PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0156798
By:
- Chen, Zhifeng;
- Zhang, Lan;
- Tang, Aimin;
- Callahan, Cheryl;
- Pristatsky, Pavlo;
- Swoyer, Ryan;
- Cejas, Pedro;
- Nahas, Debbie;
- Galli, Jennifer;
- Cosmi, Scott;
- DiStefano, Daniel;
- Hoang, Van M.;
- Bett, Andrew;
- Casimiro, Danilo;
- Vora, Kalpit A.
Publication type:
Article
Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection.
Published in:
NPJ Vaccines, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41541-020-0163-z
By:
- Espeseth, Amy S.;
- Cejas, Pedro J.;
- Citron, Michael P.;
- Wang, Dai;
- DiStefano, Daniel J.;
- Callahan, Cheryl;
- Donnell, Gregory O';
- Galli, Jennifer D.;
- Swoyer, Ryan;
- Touch, Sinoeun;
- Wen, Zhiyun;
- Antonello, Joseph;
- Zhang, Lan;
- Flynn, Jessica A.;
- Cox, Kara S.;
- Freed, Daniel C.;
- Vora, Kalpit A.;
- Bahl, Kapil;
- Latham, Andrew H.;
- Smith, Jeffrey S.
Publication type:
Article
Functional Evaluation and Genetic Evolution of Human T-Cell Responses After Vaccination With a Conditionally Replication-Defective Cytomegalovirus Vaccine.
Published in:
2021
By:
- Cox, Kara S;
- Zhang, Lu;
- Freed, Daniel C;
- Tang, Aimin;
- Zhang, Shifang;
- Zhou, Yu;
- Wang, I-Ming;
- Rupp, Richard E;
- Adler, Stuart P;
- Musey, Luwy K;
- Wang, Dai;
- Vora, Kalpit A;
- Fu, Tong-Ming
Publication type:
journal article
Effector and central memory poly-functional CD4+ and CD8+ T cells are boosted upon ZOSTAVAX® vaccination.
Published in:
Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00553
By:
- Sei, Janet J.;
- Cox, Kara S.;
- Dubey, Sheri A.;
- Antonello, Joseph M.;
- Krah, David L.;
- Casimiro, Danilo R.;
- Vora, Kalpit A.
Publication type:
Article
Respiratory syncytial virus elicits enriched CD8+ T lymphocyte responses in lung compared with blood in African green monkeys.
Published in:
PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187642
By:
- Li, Hualin;
- Callahan, Cheryl;
- Citron, Michael;
- Wen, Zhiyun;
- Touch, Sinoeun;
- Monslow, Morgan A.;
- Cox, Kara S.;
- DiStefano, Daniel J.;
- Vora, Kalpit A.;
- Bett, Andrew;
- Espeseth, Amy
Publication type:
Article

Found: 14

A Phase 1 Randomized, Double‐Blind, Placebo‐Controlled Trial to Assess the Safety, Tolerability, and Pharmacokinetics of a Respiratory Syncytial Virus Neutralizing Monoclonal Antibody MK‐1654 in Healthy Adults.

Identification and Quantification of a Pneumococcal Cell Wall Polysaccharide by Antibody-Enhanced Chromatography Assay.

Profiling of hMPV F-specific antibodies isolated from human memory B cells.

Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response.

Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses.

Neutralization Activity of Anti-drug Antibodies Against a Biotherapeutic Can Be Predicted from a Comprehensive Pharmacokinetics, Pharmacodynamics, and Anti-drug Antibody Data Analysis.

Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes.

The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment.

Development and Characterization of Monoclonal Antibodies to Staphylococcus aureus Capsule Type 5.

Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein.

Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection.

Functional Evaluation and Genetic Evolution of Human T-Cell Responses After Vaccination With a Conditionally Replication-Defective Cytomegalovirus Vaccine.

Effector and central memory poly-functional CD4<sup>+</sup> and CD8<sup>+</sup> T cells are boosted upon ZOSTAVAX® vaccination.

Respiratory syncytial virus elicits enriched CD8<sup>+</sup> T lymphocyte responses in lung compared with blood in African green monkeys.