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Demyelinating Diseases: From Molecular Mechanisms to Therapeutic Strategies.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4596, doi. 10.3390/ijms24054596
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- Article
Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3456, doi. 10.3390/ijms23073456
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- Article
Human iPSC-Derived Astrocytes: A Powerful Tool to Study Primary Astrocyte Dysfunction in the Pathogenesis of Rare Leukodystrophies.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 274, doi. 10.3390/ijms23010274
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- Article
The Antihypertensive Drug Telmisartan Protects Oligodendrocytes from Cholesterol Accumulation and Promotes Differentiation by a PPAR-γ-Mediated Mechanism.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9434, doi. 10.3390/ijms22179434
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Myelin Defects in Niemann–Pick Type C Disease: Mechanisms and Possible Therapeutic Perspectives.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8858, doi. 10.3390/ijms22168858
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- Article
DRP1 Inhibition Rescues Mitochondrial Integrity and Excessive Apoptosis in CS-A Disease Cell Models.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 7123, doi. 10.3390/ijms22137123
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- Article
Excessive Innate Immunity Steers Pathogenic Adaptive Immunity in the Development of Theiler's Virus-Induced Demyelinating Disease.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5254, doi. 10.3390/ijms22105254
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- Article
The Current Challenges for Drug Discovery in CNS Remyelination.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2891, doi. 10.3390/ijms22062891
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- Article
NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7216, doi. 10.3390/ijms21197216
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- Article
Altered outward-rectifying K<sup>+</sup> current reveals microglial activation induced by HIV-1 Tat protein.
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- Glia, 2001, v. 33, n. 3, p. 181, doi. 10.1002/1098-1136(200103)33:3<181::AID-GLIA1017>3.0.CO;2-Q
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- Article
Two different ionotropic receptors are activated by ATP in rat microglia.
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- Journal of Physiology, 1999, v. 519, n. 3, p. 723, doi. 10.1111/j.1469-7793.1999.0723n.x
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- Article
Adenosine A<sub>2A</sub> receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46268-8
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- Article
MLC1 protein: a likely link between leukodystrophies and brain channelopathies.
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- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00106
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- Article
The activity of the Striatal‐enriched protein tyrosine phosphatase in neuronal cells is modulated by adenosine A<sub>2A</sub> receptor.
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- Journal of Neurochemistry, 2020, v. 152, n. 3, p. 284, doi. 10.1111/jnc.14866
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- Article
The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.
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- Journal of Neurochemistry, 2015, v. 135, n. 1, p. 147, doi. 10.1111/jnc.13244
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- Article
TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression.
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- Journal of Neurochemistry, 2010, v. 115, n. 2, p. 450, doi. 10.1111/j.1471-4159.2010.06937.x
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- Article
Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83938-y
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- Article
Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes.
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- Human Molecular Genetics, 2016, v. 25, n. 8, p. 1543, doi. 10.1093/hmg/ddw032
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- Article
Megalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutations.
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- Human Molecular Genetics, 2012, v. 21, n. 10, p. 2166, doi. 10.1093/hmg/dds032
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- Article
A Calsequestrin-1 Mutation Associated with a Skeletal Muscle Disease Alters Sarcoplasmic Ca<sup>2+</sup> Release.
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- PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0155516
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Protein kinase C involvement in the resting and interferon-γ-induced K<sup>+</sup> channel profile of microglial cells.
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- Journal of Neuroscience Research, 1997, v. 47, n. 3, p. 233, doi. 10.1002/(SICI)1097-4547(19970201)47:3<233::AID-JNR1>3.0.CO;2-J
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The CaMKII/MLC1 Axis Confers Ca 2+ -Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes.
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- Cells (2073-4409), 2022, v. 11, n. 17, p. 2656, doi. 10.3390/cells11172656
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- Article
Megalencephalic Leukoencephalopathy with Subcortical Cysts Disease-Linked MLC1 Protein Favors Gap-Junction Intercellular Communication by Regulating Connexin 43 Trafficking in Astrocytes.
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- Cells (2073-4409), 2020, v. 9, n. 6, p. 1425, doi. 10.3390/cells9061425
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- Article
Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
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- Experimental Biology & Medicine, 2014, v. 239, n. 2, p. 213, doi. 10.1177/1535370213514317
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- Article
The Stimulation of Adenosine A<sup>2A</sup> Receptors Ameliorates the Pathological Phenotype of Fibroblasts from Niemann-Pick Type C Patients.
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- Journal of Neuroscience, 2013, v. 33, n. 39, p. 15388, doi. 10.1523/JNEUROSCI.0558-13.2013
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The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca<sup>2+</sup> waves.
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- Biological Chemistry, 2013, v. 394, n. 12, p. 1607, doi. 10.1515/hsz-2013-0152
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- Article