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Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease.
Published in:
Frontiers in Neurology, 2019, v. 10, p. 1, doi. 10.3389/fneur.2019.01140
By:
- Ding, Yu;
- Zhao, Jiahui;
- Zhang, Xunle;
- Wang, Shanshan;
- Viola, Kirsten L.;
- Chow, Frances E.;
- Zhang, Yang;
- Lippa, Carol;
- Klein, William L.;
- Gong, Yuesong
Publication type:
Article
Single Molecule Detecting Amyloid Beta Oligomers In Human Cerebrospinal Fluid With Buoyant‐Antigen‐Magnetic Assay.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083023
By:
- karimpourkalou, zahra;
- wang, chuanlie;
- Viola, Kirsten L.;
- Klein, William L.;
- Anker, jeffrey N
Publication type:
Article
Preparation and qualification of soluble amyloid beta oligomers for use in bioanalytic assays supporting Alzheimer's disease therapeutics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.067489
By:
- Cline, Erika N.;
- Vanderstichele, Hugo Marcel;
- Johnson, Derrick;
- Abdeen, Sanofar Jainul;
- McDermott, Paul;
- Cruse, James;
- Viola, Kirsten L.;
- Dean, Robert A;
- Jerecic, Jasna
Publication type:
Article
P4‐076: NON‐TRANSGENIC DIETARY‐INDUCED MODELS OF AD‐LIKE PATHOLOGY AND DEMENTIA IN THE RABBIT.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1303, doi. 10.1016/j.jalz.2019.06.3736
By:
- Weiss, Craig;
- Smith, Quinn C.;
- Procissi, Daniele;
- Bertolino, Nicola;
- Cline, Erika N.;
- Viola, Kirsten L.;
- Klein, William L.;
- Disterhoft, John F.
Publication type:
Article
An Essential Role for Alzheimer's-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2208, doi. 10.3390/ijms23042208
By:
- Bartley, Samuel C.;
- Proctor, Madison T.;
- Xia, Hongjie;
- Ho, Evelyn;
- Kang, Dong S.;
- Schuster, Kristen;
- Bicca, Maíra A.;
- Seckler, Henrique S.;
- Viola, Kirsten L.;
- Patrie, Steven M.;
- Kelleher, Neil L.;
- De Mello, Fernando G.;
- Klein, William L.
Publication type:
Article
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27572-2
By:
- Yang, Yun;
- Tapias, Victor;
- Acosta, Diana;
- Xu, Hui;
- Chen, Huanlian;
- Bhawal, Ruchika;
- Anderson, Elizabeth T.;
- Ivanova, Elena;
- Lin, Hening;
- Sagdullaev, Botir T.;
- Chen, Jianer;
- Klein, William L.;
- Viola, Kirsten L.;
- Gandy, Sam;
- Haroutunian, Vahram;
- Beal, M. Flint;
- Eliezer, David;
- Zhang, Sheng;
- Gibson, Gary E.
Publication type:
Article
An ultrasensitive immunoassay detects soluble Aβ oligomers in tg mice prior to memory loss.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P847, doi. 10.1016/j.jalz.2015.08.005
By:
- Cline, Erika N.;
- Viola, Kirsten L.;
- Rollins, Madeline G.;
- Mohammad, Saad N.;
- Zieske, Lynn R.;
- Klein, William L.
Publication type:
Article
Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease.
Published in:
Nature Nanotechnology, 2015, v. 10, n. 1, p. 91, doi. 10.1038/nnano.2014.254
By:
- Viola, Kirsten L.;
- Sbarboro, James;
- Sureka, Ruchi;
- De, Mrinmoy;
- Bicca, Maíra A.;
- Wang, Jane;
- Vasavada, Shaleen;
- Satpathy, Sreyesh;
- Wu, Summer;
- Joshi, Hrushikesh;
- Velasco, Pauline T.;
- MacRenaris, Keith;
- Waters, E. Alex;
- Lu, Chang;
- Phan, Joseph;
- Lacor, Pascale;
- Prasad, Pottumarthi;
- Dravid, Vinayak P.;
- Klein, William L.
Publication type:
Article
AβOligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 4, p. 796, doi. 10.1523/JNEUROSCI.3501-06.2007
By:
- Lacor, Pascale N.;
- Buniel, Maria C.;
- Furlow, Paul W.;
- Clemente, Antonio Sanz;
- Velasco, Pauline T.;
- Wood, Margaret;
- Viola, Kirsten L.;
- Klein, William L.
Publication type:
Article
Intrathecal amyloid‐beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's disease.
Published in:
Neuropathology & Applied Neurobiology, 2022, v. 48, n. 4, p. 1, doi. 10.1111/nan.12800
By:
- Wakeman, Dustin R.;
- Weed, Michael R.;
- Perez, Sylvia E.;
- Cline, Erika N.;
- Viola, Kirsten L.;
- Wilcox, Kyle C.;
- Moddrelle, David S.;
- Nisbett, Ernell Z.;
- Kurian, Anish M.;
- Bell, Amanda F.;
- Pike, Ricaldo;
- Jacobson, Peer B.;
- Klein, William L.;
- Mufson, Elliott J.;
- Lawrence, Matthew S.;
- Elsworth, John D.
Publication type:
Article
Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer's patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability.
Published in:
Neuropathology & Applied Neurobiology, 2021, v. 47, n. 4, p. 488, doi. 10.1111/nan.12674
By:
- Kelly, Louise;
- Seifi, Mohsen;
- Ma, Ruolin;
- Mitchell, Scott J.;
- Rudolph, Uwe;
- Viola, Kirsten L.;
- Klein, William L.;
- Lambert, Jeremy J.;
- Swinny, Jerome D.
Publication type:
Article
A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers.
Published in:
Journal of Neurochemistry, 2017, v. 142, n. 6, p. 934, doi. 10.1111/jnc.14118
By:
- Sebollela, Adriano;
- Cline, Erika N.;
- Popova, Izolda;
- Luo, Kevin;
- Sun, Xiaoxia;
- Ahn, Jay;
- Barcelos, Milena A.;
- Bezerra, Vanessa N.;
- Lyra e Silva, Natalia M.;
- Patel, Jason;
- Pinheiro, Nathalia R.;
- Qin, Lei A.;
- Kamel, Josette M.;
- Weng, Anthea;
- DiNunno, Nadia;
- Bebenek, Adrian M.;
- Velasco, Pauline T.;
- Viola, Kirsten L.;
- Lacor, Pascale N.;
- Ferreira, Sergio T.
Publication type:
Article
Diet-induced Alzheimer's-like syndrome in the rabbit.
Published in:
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2022, v. 8, n. 1, p. 1, doi. 10.1002/trc2.12241
By:
- Weiss, Craig;
- Bertolino, Nicola;
- Procissi, Daniele;
- Aleppo, Grazia;
- Smith, Quinn C.;
- Viola, Kirsten L.;
- Bartley, Samuel C.;
- Klein, William L.;
- Disterhoft, John F.
Publication type:
Article
Aβ oligomer induced cognitive impairment and evaluation of ACU193‐MNS‐based MRI in rabbit.
Published in:
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12087
By:
- Rozema, Nicholas B.;
- Procissi, Daniele;
- Bertolino, Nicola;
- Viola, Kirsten L.;
- Nandwana, Vikas;
- Abdul, Nafay;
- Pribus, Sophia;
- Dravid, Vinayak;
- Klein, William L.;
- Disterhoft, John F.;
- Weiss, Craig
Publication type:
Article
Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in APP/PS1 mice.
Published in:
Psychopharmacology, 2023, v. 240, n. 12, p. 2641, doi. 10.1007/s00213-023-06459-8
By:
- Rodriguez, Guadalupe;
- Eren, Mesut;
- Haupfear, Isabel;
- Viola, Kirsten L.;
- Cline, Erika N.;
- Miyata, Toshio;
- Klein, William L.;
- Vaughan, Douglas E.;
- Dong, Hongxin
Publication type:
Article
Monoclonal antibodies that target pathological assemblies of Aβ.
Published in:
Journal of Neurochemistry, 2007, v. 100, n. 1, p. 23, doi. 10.1111/j.1471-4159.2006.04157.x
By:
- Lambert, Mary P.;
- Velasco, Pauline T.;
- Chang, Lei;
- Viola, Kirsten L.;
- Fernandez, Sara;
- Lacor, Pascale N.;
- Khuon, Daliya;
- Gong, Yuesong;
- Bigio, Eileen H.;
- Shaw, Pamela;
- De Felice, Fernanda G.;
- Krafft, Grant A.;
- Klein, William L.
Publication type:
Article
Reversible Inactivation of Superoxide-Sensitive Aconitase in Aβ1-42-Treated Neuronal Cell Lines.
Published in:
Journal of Neurochemistry, 2000, v. 75, n. 5, p. 1977, doi. 10.1046/j.1471-4159.2000.0751977.x
By:
- Longo, Valter D.;
- Viola, Kirsten L.;
- Klein, William L.;
- Finch, Caleb E.
Publication type:
Article
The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease.
Published in:
Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2021.768646
By:
- Viola, Kirsten L.;
- Bicca, Maira A.;
- Bebenek, Adrian M.;
- Kranz, Daniel L.;
- Nandwana, Vikas;
- Waters, Emily A.;
- Haney, Chad R.;
- Lee, Maxwell;
- Gupta, Abhay;
- Brahmbhatt, Zachary;
- Huang, Weijian;
- Chang, Ting-Tung;
- Peck, Anderson;
- Valdez, Clarissa;
- Dravid, Vinayak P.;
- Klein, William L.
Publication type:
Article

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