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Blocking EGFR Activation with Anti‐EGF Nanobodies via Two Distinct Molecular Recognition Mechanisms.
Published in:
Angewandte Chemie, 2018, v. 130, n. 42, p. 14039, doi. 10.1002/ange.201807736
By:
- Guardiola, Salvador;
- Varese, Monica;
- Sánchez‐navarro, Macarena;
- Vincke, Cécile;
- Teixidó, Meritxell;
- García, Jesús;
- Muyldermans, Serge;
- Giralt, Ernest
Publication type:
Article
Ultrasensitive Measurement of Ca<sup>2+</sup> Influx into Lipid Vesicles Induced by Protein Aggregates.
Published in:
Angewandte Chemie, 2017, v. 129, n. 27, p. 7858, doi. 10.1002/ange.201700966
By:
- Flagmeier, Patrick;
- De, Suman;
- Wirthensohn, David C.;
- Lee, Steven F.;
- Vincke, Cécile;
- Muyldermans, Serge;
- Knowles, Tuomas P. J.;
- Gandhi, Sonia;
- Dobson, Christopher M.;
- Klenerman, David
Publication type:
Article
Development of Nanobodies against Mal de Río Cuarto virus major viroplasm protein P9-1 for diagnostic sandwich ELISA and immunodetection.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99275-z
By:
- Llauger, Gabriela;
- Monti, Demián;
- Adúriz, Matías;
- Romão, Ema;
- Dumón, Analía Delina;
- Mattio, María Fernanda;
- Wigdorovitz, Andrés;
- Muyldermans, Serge;
- Vincke, Cécile;
- Parreño, Viviana;
- del Vas, Mariana
Publication type:
Article
Epitope structure and binding affinity of single chain llama anti-β-amyloid antibodies revealed by proteolytic excision affinity-mass spectrometry.
Published in:
Journal of Molecular Recognition, 2013, v. 26, n. 1, p. 1, doi. 10.1002/jmr.2210
By:
- Paraschiv, Gabriela;
- Vincke, Cécile;
- Czaplewska, Paulina;
- Manea, Marilena;
- Muyldermans, Serge;
- Przybylski, Michael
Publication type:
Article
A few good reasons to use nanobodies for cancer treatment.
Published in:
European Journal of Immunology, 2023, v. 53, n. 9, p. 1, doi. 10.1002/eji.202250024
By:
- Jumapili, Neema Ahishakiye;
- Zivalj, Maida;
- Barthelmess, Romina Mora;
- Raes, Geert;
- De Groof, Timo W. M.;
- Devoogdt, Nick;
- Stijlemans, Benoît;
- Vincke, Cécile;
- Van Ginderachter, Jo A.
Publication type:
Article
AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model.
Published in:
EMBO Molecular Medicine, 2022, v. 14, n. 4, p. 1, doi. 10.15252/emmm.201809824
By:
- Marino, Marika;
- Zhou, Lujia;
- Rincon, Melvin Y;
- Callaerts‐Vegh, Zsuzsanna;
- Verhaert, Jens;
- Wahis, Jérôme;
- Creemers, Eline;
- Yshii, Lidia;
- Wierda, Keimpe;
- Saito, Takashi;
- Marneffe, Catherine;
- Voytyuk, Iryna;
- Wouters, Yessica;
- Dewilde, Maarten;
- Duqué, Sandra I;
- Vincke, Cécile;
- Levites, Yona;
- Golde, Todd E;
- Saido, Takaomi C;
- Muyldermans, Serge
Publication type:
Article
Inactivation of γ-secretases leads to accumulation of substrates and non-Alzheimer neurodegeneration.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 8, p. 1088, doi. 10.15252/emmm.201707561
By:
- Acx, Hermien;
- Serneels, Lutgarde;
- Radaelli, Enrico;
- Muyldermans, Serge;
- Vincke, Cécile;
- Pepermans, Elise;
- Müller, Ulrike;
- Chávez ‐ Gutiérrez, Lucía;
- De Strooper, Bart
Publication type:
Article
Blocking EGFR Activation with Anti‐EGF Nanobodies via Two Distinct Molecular Recognition Mechanisms.
Published in:
Angewandte Chemie International Edition, 2018, v. 57, n. 42, p. 13843, doi. 10.1002/anie.201807736
By:
- Guardiola, Salvador;
- Varese, Monica;
- Sánchez‐navarro, Macarena;
- Vincke, Cécile;
- Teixidó, Meritxell;
- García, Jesús;
- Muyldermans, Serge;
- Giralt, Ernest
Publication type:
Article
Ultrasensitive Measurement of Ca<sup>2+</sup> Influx into Lipid Vesicles Induced by Protein Aggregates.
Published in:
Angewandte Chemie International Edition, 2017, v. 56, n. 27, p. 7750, doi. 10.1002/anie.201700966
By:
- Flagmeier, Patrick;
- De, Suman;
- Wirthensohn, David C.;
- Lee, Steven F.;
- Vincke, Cécile;
- Muyldermans, Serge;
- Knowles, Tuomas P. J.;
- Gandhi, Sonia;
- Dobson, Christopher M.;
- Klenerman, David
Publication type:
Article
Nanobodies for the Early Detection of Ovarian Cancer.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13687, doi. 10.3390/ijms232213687
By:
- Tran, Lan-Huong;
- Graulus, Geert-Jan;
- Vincke, Cécile;
- Smiejkowska, Natalia;
- Kindt, Anne;
- Devoogdt, Nick;
- Muyldermans, Serge;
- Adriaensens, Peter;
- Guedens, Wanda
Publication type:
Article
Intrabody Targeting HIF-1α Mediates Transcriptional Downregulation of Target Genes Related to Solid Tumors.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12335, doi. 10.3390/ijms222212335
By:
- Hu, Yaozhong;
- Romão, Ema;
- Vincke, Cécile;
- Brys, Lea;
- Elkrim, Yvon;
- Vandevenne, Marylène;
- Liu, Changxiao;
- Muyldermans, Serge
Publication type:
Article
Identification of Nanobodies against the Acute Myeloid Leukemia Marker CD33.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 310, doi. 10.3390/ijms21010310
By:
- Romão, Ema;
- Krasniqi, Ahmet;
- Maes, Laila;
- Vandenbrande, Camille;
- Sterckx, Yann G.-J.;
- Stijlemans, Benoit;
- Vincke, Cécile;
- Devoogdt, Nick;
- Muyldermans, Serge
Publication type:
Article
Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.
Published in:
Biochemical Journal, 2014, v. 459, n. 1, p. 59, doi. 10.1042/BJ20131399
By:
- CHAIKUAD, Apirat;
- KEATES, Tracy;
- VINCKE, Cécile;
- KAUFHOLZ, Melanie;
- ZENN, Michael;
- ZIMMERMANN, Bastian;
- GUTIÉRREZ, Carlos;
- Rong-guang ZHANG;
- HATZOS-SKINTGES, Catherine;
- JOACHIMIAK, Andrzej;
- MUYLDERMANS, Serge;
- HERBERG, Friedrich W.;
- KNAPP, Stefan;
- MÜLLER, Susanne
Publication type:
Article
Neutralizing Dromedary-Derived Nanobodies Against BotI-Like Toxin From the Most Hazardous Scorpion Venom in the Middle East and North Africa Region.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.863012
By:
- Ben Abderrazek, Rahma;
- Ksouri, Ayoub;
- Idoudi, Faten;
- Dhaouadi, Sayda;
- Hamdi, Emna;
- Vincke, Cécile;
- Farah, Azer;
- Benlasfar, Zakaria;
- Majdoub, Hafedh;
- El Ayeb, Mohamed;
- Muyldermans, Serge;
- Bouhaouala-Zahar, Balkiss
Publication type:
Article
Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells.
Published in:
Scientific Reports, 2016, p. 31910, doi. 10.1038/srep31910
By:
- Drews, Anna;
- Flint, Jennie;
- Shivji, Nadia;
- Jönsson, Peter;
- Wirthensohn, David;
- De Genst, Erwin;
- Vincke, Cécile;
- Muyldermans, Serge;
- Dobson, Chris;
- Klenerman, David
Publication type:
Article
Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46067-4
By:
- Stijlemans, Benoit;
- De Baetselier, Patrick;
- Van Molle, Inge;
- Lecordier, Laurence;
- Hendrickx, Erika;
- Romão, Ema;
- Vincke, Cécile;
- Baetens, Wendy;
- Schoonooghe, Steve;
- Hassanzadeh-Ghassabeh, Gholamreza;
- Korf, Hannelie;
- Wallays, Marie;
- Pinto Torres, Joar E.;
- Perez-Morga, David;
- Brys, Lea;
- Campetella, Oscar;
- Leguizamón, María S.;
- Claes, Mathieu;
- Hendrickx, Sarah;
- Mabille, Dorien
Publication type:
Article
Development of Nanobodies Against Hemorrhagic and Myotoxic Components of Bothrops atrox Snake Venom.
Published in:
Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00655
By:
- Bailon Calderon, Henri;
- Yaniro Coronel, Verónica Olga;
- Cáceres Rey, Omar Alberto;
- Colque Alave, Elizabeth Gaby;
- Leiva Duran, Walter Jhon;
- Padilla Rojas, Carlos;
- Montejo Arevalo, Harrison;
- García Neyra, David;
- Galarza Pérez, Marco;
- Bonilla, César;
- Tintaya, Benigno;
- Ricciardi, Giulia;
- Smiejkowska, Natalia;
- Romão, Ema;
- Vincke, Cécile;
- Lévano, Juan;
- Celys, Mary;
- Lomonte, Bruno;
- Muyldermans, Serge
Publication type:
Article
Generation and Characterization of Novel Pan‐Cancer Anti‐uPAR Fluorescent Nanobodies as Tools for Image‐Guided Surgery.
Published in:
Advanced Science, 2024, v. 11, n. 30, p. 1, doi. 10.1002/advs.202400700
By:
- Mateusiak, Łukasz;
- Floru, Sam;
- De Groof, Timo W. M.;
- Wouters, Janne;
- Declerck, Noemi B.;
- Debie, Pieterjan;
- Janssen, Simone;
- Zeven, Katty;
- Puttemans, Janik;
- Vincke, Cécile;
- Breckpot, Karine;
- Devoogdt, Nick;
- Hernot, Sophie
Publication type:
Article
Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer.
Published in:
FASEB Journal, 2011, v. 25, n. 7, p. 2433, doi. 10.1096/fj.10-180331
By:
- Vaneycken, Ilse;
- Devoogdt, Nick;
- Van Gassen, Naomi;
- Vincke, Cécile;
- Xavier, Catarina;
- Wernery, Ulrich;
- Muyldermans, Serge;
- Lahoutte, Tony;
- Caveliers, Vicky
Publication type:
Article
A bispecific nanobody to provide full protection against lethal scorpion envenoming.
Published in:
FASEB Journal, 2010, v. 24, n. 9, p. 3479, doi. 10.1096/fj.09-148213
By:
- Hmila, Issam;
- Saerens, Dirk;
- Abderrazek, Rahma Ben;
- Vincke, Cécile;
- Abidi, Naima;
- Benlasfar, Zakaria;
- Govaert, Jochen;
- Ayeb, Mohamed El;
- Bouhaouala-Zahar, Balkiss;
- Muyldermans, Serge
Publication type:
Article
Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal β‐1,3‐Glucanosyltransferases.
Published in:
Angewandte Chemie, 2024, v. 136, n. 34, p. 1, doi. 10.1002/ange.202405823
By:
- Redrado‐Hernández, Sergio;
- Macías‐León, Javier;
- Castro‐López, Jorge;
- Belén Sanz, Ana;
- Dolader, Elena;
- Arias, Maykel;
- González‐Ramírez, Andrés Manuel;
- Sánchez‐Navarro, David;
- Petryk, Yuliya;
- Farkaš, Vladimír;
- Vincke, Cécile;
- Muyldermans, Serge;
- García‐Barbazán, Irene;
- del Agua, Celia;
- Zaragoza, Oscar;
- Arroyo, Javier;
- Pardo, Julián;
- Gálvez, Eva M.;
- Hurtado‐Guerrero, Ramon
Publication type:
Article
Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal β‐1,3‐Glucanosyltransferases.
Published in:
Angewandte Chemie International Edition, 2024, v. 63, n. 34, p. 1, doi. 10.1002/anie.202405823
By:
- Redrado‐Hernández, Sergio;
- Macías‐León, Javier;
- Castro‐López, Jorge;
- Belén Sanz, Ana;
- Dolader, Elena;
- Arias, Maykel;
- González‐Ramírez, Andrés Manuel;
- Sánchez‐Navarro, David;
- Petryk, Yuliya;
- Farkaš, Vladimír;
- Vincke, Cécile;
- Muyldermans, Serge;
- García‐Barbazán, Irene;
- del Agua, Celia;
- Zaragoza, Oscar;
- Arroyo, Javier;
- Pardo, Julián;
- Gálvez, Eva M.;
- Hurtado‐Guerrero, Ramon
Publication type:
Article
In Vitro Analysis and In Vivo Tumor Targeting of a Humanized, Grafted Nanobody in Mice Using Pinhole SPECT/Micro-CT.
Published in:
Journal of Nuclear Medicine, 2010, v. 51, n. 7, p. 1099, doi. 10.2967/jnumed.109.069823
By:
- Vaneycken, Ilse;
- Govaert, Jochen;
- Vincke, Cécile;
- Caveliers, Vicky;
- Lahoutte, Tony;
- De Baetselier, Patrick;
- Raes, Geert;
- Bossuyt, Axel;
- Muyldermans, Serge;
- Devoogdt, Nick
Publication type:
Article
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting.
Published in:
Theranostics, 2023, v. 13, n. 1, p. 355, doi. 10.7150/thno.77560
By:
- Erreni, Marco;
- D'Autilia, Francesca;
- Avigni, Roberta;
- Bolli, Evangelia;
- Arnouk, Sana M.;
- Movahedi, Kiavash;
- Debie, Pieterjan;
- Anselmo, Achille;
- Parente, Raffaella;
- Vincke, Cécile;
- van Leeuwen, Fijs W. B.;
- Allavena, Paola;
- Garlanda, Cecilia;
- Mantovani, Alberto;
- Doni, Andrea;
- Hernot, Sophie;
- Van Ginderachter, Jo A.
Publication type:
Article
Whole-mouse clearing and imaging at the cellular level with vDISCO.
Published in:
Nature Protocols, 2023, v. 18, n. 4, p. 1197, doi. 10.1038/s41596-022-00788-2
By:
- Cai, Ruiyao;
- Kolabas, Zeynep Ilgin;
- Pan, Chenchen;
- Mai, Hongcheng;
- Zhao, Shan;
- Kaltenecker, Doris;
- Voigt, Fabian F.;
- Molbay, Muge;
- Ohn, Tzu-lun;
- Vincke, Cécile;
- Todorov, Mihail I.;
- Helmchen, Fritjof;
- Van Ginderachter, Jo A.;
- Ertürk, Ali
Publication type:
Article
Development of Nanobodies Targeting Peste des Petits Ruminants Virus: The Prospect in Disease Diagnosis and Therapy.
Published in:
Animals (2076-2615), 2021, v. 11, n. 8, p. 2206, doi. 10.3390/ani11082206
By:
- Kinimi, Edson;
- Muyldermans, Serge;
- Vincke, Cécile;
- Odongo, Steven;
- Kock, Richard;
- Parida, Satya;
- Mahapatra, Mana;
- Misinzo, Gerald
Publication type:
Article
Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII Scorpion toxin.
Published in:
PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 9, p. 727, doi. 10.1093/protein/gzr037
By:
- Ben Abderrazek, Rahma;
- Vincke, Cécile;
- Hmila, Issam;
- Saerens, Dirk;
- Abidi, Naima;
- El Ayeb, Mohamed;
- Muyldermans, Serge;
- Bouhaouala-Zahar, Balkiss
Publication type:
Article

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