Found: 22

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  • Amyloid beta plaque accumulation with longitudinal [18F]AZD4694 PET.

    Published in:
    Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2023, v. 15, n. 3, p. 1, doi. 10.1002/dad2.12391
    By:
    • Therriault, Joseph;
    • Lussier, Firoza Z.;
    • Tissot, Cécile;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Kunach, Peter;
    • Wang, Yi‐Ting;
    • Fernandez‐Arias, Jaime;
    • Vermeiren, Marie;
    • Pascoal, Tharick A.;
    • Massarweh, Gassan;
    • Vitali, Paolo;
    • Soucy, Jean‐Paul;
    • Saha‐Chaudhuri, Paramita;
    • Gauthie, Serge;
    • Rosa‐Neto, Pedro
    Publication type:
    Article

  • The Use of Tau PET to Stage Alzheimer Disease According to the Braak Staging Framework.

    Published in:
    Journal of Nuclear Medicine, 2023, v. 64, n. 8, p. 1171, doi. 10.2967/jnumed.122.265200
    By:
    • Macedo, Arthur C.;
    • Tissot, Cécile;
    • Therriault, Joseph;
    • Servaes, Stijn;
    • Yi-Ting Wang;
    • Fernandez-Arias, Jaime;
    • Rahmouni, Nesrine;
    • Lussier, Firoza Z.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Vitali, Paolo;
    • Kok Pin Ng;
    • Zimmer, Eduardo R.;
    • Guiot, Marie-Christine;
    • Pascoal, Tharick A.;
    • Gauthier, Serge;
    • Rosa-Neto, Pedro
    Publication type:
    Article

  • Predicting functional decline in aging and Alzheimer's disease with PET-based Braak staging.

    Published in:
    Brain Communications, 2024, v. 6, n. 2, p. 1, doi. 10.1093/braincomms/fcae043
    By:
    • Macedo, Arthur C;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Fernandez-Arias, Jaime;
    • Ferreira, Pamela C L;
    • Vitali, Paolo;
    • Servaes, Stijn;
    • Rahmouni, Nesrine;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Lussier, Firoza Z;
    • Stevenson, Jenna;
    • Wang, Yi-Ting;
    • Socualaya, Kely Quispialaya;
    • Kunach, Peter;
    • Nazneen, Tahnia;
    • Hosseini, Seyyed Ali;
    • Pallen, Vanessa;
    • Stevenson, Alyssa;
    • Ferrari-Souza, João Pedro
    Publication type:
    Article

  • Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography.

    Published in:
    JAMA Neurology, 2023, v. 80, n. 2, p. 188, doi. 10.1001/jamaneurol.2022.4485
    By:
    • Therriault, Joseph;
    • Vermeiren, Marie;
    • Servaes, Stijn;
    • Tissot, Cécile;
    • Ashton, Nicholas J.;
    • Benedet, Andréa Lessa;
    • Karikari, Thomas K.;
    • Lantero-Rodriguez, Juan;
    • Brum, Wagner S.;
    • Lussier, Firoza Z.;
    • Bezgin, Gleb;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Kunach, Peter;
    • Wang, Yi-Ting;
    • Fernandez-Arias, Jaime;
    • Socualaya, Kely Quispialaya;
    • Macedo, Arthur C.;
    • Ferrari-Souza, João Pedro;
    • Ferreira, Pâmela C. L.
    Publication type:
    Article

  • Microglial Activation Contributes to Neuropsychiatric Dysfunction in Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079969
    By:
    • Aguzzoli, Cristiano Schaffer;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Soares, Carolina;
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb
    Publication type:
    Article

  • Association of reactive astrogliosis and microglial activation with tau pathology in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078423
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Benedet, Andrea Lessa;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Zalzale, Hussein;
    • Rohden, Francieli;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Potential utility of using both APOEε4 and Aβ positivity to enrich clinical trials of tau‐targeting therapies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079764
    By:
    • Ferrari‐Souza, João Pedro;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Benedet, Andrea Lessa;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • APOEε4 potentiates the effects of Aβ pathology on the deposition of neurofibrillary tangles via tau phosphorylation.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079681
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Benedet, Andrea Lessa;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • CSF total tau is more closely associated with synaptic dysfunction than overt neurodegeneration.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079855
    By:
    • Soares, Carolina;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Aguzzoli, Cristiano Schaffer;
    • Ferrari‐Souza, João Pedro;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb
    Publication type:
    Article

  • Synaptic dysfunction, Tau pathology and Neurodegeneration.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080006
    By:
    • Soares, Carolina;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Aguzzoli, Cristiano Schaffer;
    • Rohden, Francieli;
    • Ferrari‐Souza, João Pedro;
    • Zalzale, Hussein;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Association of reactive astrogliosis and microglial activation with tau pathology in Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.082041
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Benedet, Andrea Lessa;
    • Soares, Carolina;
    • Aguzzoli, Cristiano Schaffer;
    • Zalzale, Hussein;
    • Rohden, Francieli;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Synaptic dysfunction in the presence of tau tangles is not a strong predictor of atrophy.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081954
    By:
    • Soares, Carolina;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Aguzzoli, Cristiano Schaffer;
    • Rohden, Francieli;
    • Ferrari‐Souza, João Pedro;
    • Zalzale, Hussein;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su
    Publication type:
    Article

  • Microglial Activation Contributes to Neuropsychiatric Dysfunction in Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081950
    By:
    • Aguzzoli, Cristiano Schaffer;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Soares, Carolina;
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb
    Publication type:
    Article

  • CSF total tau is more closely associated with synaptic dysfunction than overt neurodegeneration.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081943
    By:
    • Soares, Carolina;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Povala, Guilherme;
    • Aguzzoli, Cristiano Schaffer;
    • Ferrari‐Souza, João Pedro;
    • Zalzale, Hussein;
    • Lussier, Firoza Z;
    • Rohden, Francieli;
    • Abbas, Sarah;
    • Lemaire, Peter Charles;
    • Leffa, Douglas Teixeira;
    • Cabrera, Arlec;
    • Therriault, Joseph;
    • Benedet, Andrea Lessa;
    • Tissot, Cécile;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb
    Publication type:
    Article

  • Potential utility of using both APOEε4 and Aβ positivity to enrich clinical trials of tau‐targeting therapies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081933
    By:
    • Ferrari‐Souza, João Pedro;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Benedet, Andrea Lessa;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • APOEε4 potentiates the effects of Aβ pathology on the deposition of neurofibrillary tangles via tau phosphorylation.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081925
    By:
    • Ferrari‐Souza, João Pedro;
    • Bellaver, Bruna;
    • Ferreira, Pamela C.L.;
    • Benedet, Andrea Lessa;
    • Povala, Guilherme;
    • Lussier, Firoza Z;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Soares, Carolina;
    • Wang, Yi‐Ting;
    • Chamoun, Mira;
    • Servaes, Stijn;
    • Macedo, Arthur C.;
    • Vermeiren, Marie;
    • Bezgin, Gleb;
    • Kang, Min Su;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Pallen, Vanessa
    Publication type:
    Article

  • Plasma p‐tau231 and p‐tau217 inform on tau tangles aggregation in cognitively impaired individuals.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 4463, doi. 10.1002/alz.13393
    By:
    • Ferreira, Pamela C. L.;
    • Therriault, Joseph;
    • Tissot, Cécile;
    • Ferrari‐Souza, João Pedro;
    • Benedet, Andréa L.;
    • Povala, Guilherme;
    • Bellaver, Bruna;
    • Leffa, Douglas T.;
    • Brum, Wagner S.;
    • Lussier, Firoza Z.;
    • Bezgin, Gleb;
    • Servaes, Stijn;
    • Vermeiren, Marie;
    • Macedo, Arthur C.;
    • Cabrera, Arlec;
    • Stevenson, Jenna;
    • Triana‐Baltzer, Gallen;
    • Kolb, Hartmuth;
    • Rahmouni, Nesrine;
    • Klunk, William E.
    Publication type:
    Article

  • Blood‐brain barrier integrity impacts the use of plasma amyloid‐β as a proxy of brain amyloid‐β pathology.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 9, p. 3815, doi. 10.1002/alz.13014
    By:
    • Bellaver, Bruna;
    • Puig‐Pijoan, Albert;
    • Ferrari‐Souza, João Pedro;
    • Leffa, Douglas T.;
    • Lussier, Firoza Z.;
    • Ferreira, Pamela C. L.;
    • Tissot, Cécile;
    • Povala, Guilherme;
    • Therriault, Joseph;
    • Benedet, Andréa L.;
    • Ashton, Nicholas J.;
    • Servaes, Stijn;
    • Chamoun, Mira;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Vermeiren, Marie;
    • Macedo, Arthur C.;
    • Fernández‐Lebrero, Aida;
    • García‐Escobar, Greta;
    • Navalpotro‐Gómez, Irene
    Publication type:
    Article

  • Impact of meningeal and age‐related off‐target binding on longitudinal [<sup>18</sup>F]MK6240 quantification.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.066227
    By:
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Servaes, Stijn;
    • Bezgin, Gleb;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Vermeiren, Marie;
    • Kunach, Peter;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Chamoun, Mira;
    • Benedet, Andréa Lessa;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Kang, Min Su;
    • Villemagne, Victor L;
    • Tudorascu, Dana L
    Publication type:
    Article

  • Tau phosphorylation is more closely associated with amyloid‐β plaques than with tau neurofibrillary tangles.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.064277
    By:
    • Vermeiren, Marie;
    • Therriault, Joseph;
    • Servaes, Stijn;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Pascoal, Tharick A;
    • Chamoun, Mira;
    • Bezgin, Gleb;
    • Benedet, Andréa Lessa;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Kunach, Peter;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Massarweh, Gassan;
    • Vitali, Paolo;
    • Soucy, Jean‐Paul
    Publication type:
    Article

  • Impact of meningeal and age‐related off‐target binding on longitudinal [<sup>18</sup>F]MK6240 quantification.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.068139
    By:
    • Tissot, Cécile;
    • Lussier, Firoza Z;
    • Ferrari‐Souza, João Pedro;
    • Servaes, Stijn;
    • Bezgin, Gleb;
    • Ferreira, Pamela C.L.;
    • Bellaver, Bruna;
    • Leffa, Douglas Teixeira;
    • Therriault, Joseph;
    • Vermeiren, Marie;
    • Kunach, Peter;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Chamoun, Mira;
    • Benedet, Andréa Lessa;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Kang, Min Su;
    • Villemagne, Victor L;
    • Tudorascu, Dana L
    Publication type:
    Article

  • Tau phosphorylation is more closely associated with amyloid‐β plaques than with tau neurofibrillary tangles.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.064231
    By:
    • Vermeiren, Marie;
    • Therriault, Joseph;
    • Servaes, Stijn;
    • Lussier, Firoza Z;
    • Tissot, Cécile;
    • Pascoal, Tharick A;
    • Chamoun, Mira;
    • Bezgin, Gleb;
    • Benedet, Andréa Lessa;
    • Ashton, Nicholas J.;
    • Karikari, Thomas K;
    • Rodriguez, Juan Lantero;
    • Stevenson, Jenna;
    • Rahmouni, Nesrine;
    • Kunach, Peter;
    • Wang, Yi‐Ting;
    • Arias, Jaime Fernandez;
    • Vitali, Paolo;
    • Massarweh, Gassan;
    • Soucy, Jean‐Paul
    Publication type:
    Article