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Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann- Pick disease type C.
Published in:
European Journal of Immunology, 2012, v. 42, n. 7, p. 1886, doi. 10.1002/eji.201141821
By:
- Speak, Anneliese O.;
- Platt, Nicholas;
- Salio, Mariolina;
- te Vruchte, Danielle;
- Smith, David A.;
- Shepherd, Dawn;
- Veerapen, Natacha;
- Besra, Gurdyal S.;
- Yanjanin, Nicole M.;
- Simmons, Louise;
- Imrie, Jackie;
- Wraith, James E.;
- Lachmann, Robin H.;
- Hartung, Ralf;
- Runz, Heiko;
- Mengel, Eugen;
- Beck, Michael;
- Hendriksz, Christian J.;
- Porter, Forbes D.;
- Cerundolo, Vincenzo
Publication type:
Article
Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function.
Published in:
2010
By:
- Zeissig, Sebastian;
- Dougan, Stephanie K.;
- Barral, Duarte C.;
- Junker, Yvonne;
- Zhangguo Chen;
- Kaser, Arthur;
- Ho, Madelyn;
- Mandel, Hannah;
- McIntyre, Adam;
- Kennedy, Susan M.;
- Painter, Gavin F.;
- Veerapen, Natacha;
- Besra, Gurdyal S.;
- Cerundolo, Vincenzo;
- Simon Yue;
- Beladi, Sarah;
- Behar, Samuel M.;
- Xiuxu Chen;
- Gumperz, Jenny E.;
- Breckpot, Karine
Publication type:
journal article
Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.
Published in:
2008
By:
- Santo, Carmela De;
- Salio, Mariolina;
- Masri, S. Hajar;
- Lee, Laurel Yong-Hwa;
- Dong, Tao;
- Speak, Anneliese O.;
- Porubsky, Stefan;
- Booth, Sarah;
- Veerapen, Natacha;
- Besra, Gurdyal S.;
- Gröne, Hermann-Josef;
- Platt, Frances M.;
- Zambon, Maria;
- Cerundolo, Vincenzo;
- De Santo, Carmela;
- Gröne, Hermann-Josef
Publication type:
journal article
A humanized mouse model for in vivo evaluation of invariant Natural Killer T cell responses.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1011209
By:
- Saavedra-Avila, Noemi Alejandra;
- Dellabona, Paolo;
- Casorati, Giulia;
- Veerapen, Natacha;
- Besra, Gurdyal S.;
- Howell, Amy R.;
- Porcelli, Steven A.
Publication type:
Article
DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39300-z
By:
- Abrahams, Katherine A.;
- Batt, Sarah M.;
- Gurcha, Sudagar S.;
- Veerapen, Natacha;
- Bashiri, Ghader;
- Besra, Gurdyal S.
Publication type:
Article
MKAN27435 Is Required for the Biosynthesis of Higher Subclasses of Lipooligosaccharides in Mycobacterium kansasii.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0122804
By:
- Nataraj, Vijayashankar;
- Pang, Poh-choo;
- Haslam, Stuart M.;
- Veerapen, Natacha;
- Minnikin, David E.;
- Dell, Anne;
- Besra, Gurdyal S.;
- Bhatt, Apoorva
Publication type:
Article
α-Galactosylceramide Analogs with Weak Agonist Activity for Human iNKT Cells Define New Candidate Anti-Inflammatory Agents.
Published in:
PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014374
By:
- Bricard, Gabriel;
- Venkataswamy, Manjunatha M.;
- Yu, Karl O. A.;
- Im, Jin S.;
- Ndonye, Rachel M.;
- Howell, Amy R.;
- Veerapen, Natacha;
- Illarionov, Petr A.;
- Besra, Gurdyal S.;
- Qian Li;
- Young-Tae Chang;
- Porcelli, Steven A.
Publication type:
Article
Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01580
By:
- Melo, Ashanty M.;
- O'Brien, Aisling M.;
- Phelan, James J.;
- Kennedy, Susan A.;
- Wood, Nicole A. W.;
- Veerapen, Natacha;
- Besra, Gurdyal S.;
- Clarke, Niamh E.;
- Foley, Emma K.;
- Ravi, Akshaya;
- MacCarthy, Finbar;
- O'Toole, Dermot;
- Ravi, Narayamasami;
- Reynolds, John V.;
- Conroy, Melissa J.;
- Hogan, Andrew E.;
- O'Sullivan, Jacintha;
- Dunne, Margaret R.
Publication type:
Article
The hydrolase LpqI primes mycobacterial peptidoglycan recycling.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10586-2
By:
- Moynihan, Patrick J.;
- Cadby, Ian T.;
- Veerapen, Natacha;
- Jankute, Monika;
- Crosatti, Marialuisa;
- Mukamolova, Galina V.;
- Lovering, Andrew L.;
- Besra, Gurdyal S.
Publication type:
Article
Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06646-8
By:
- Chandra, Shilpi;
- Gray, James;
- Kiosses, William B.;
- Khurana, Archana;
- Hitomi, Kaori;
- Crosby, Catherine M.;
- Chawla, Ashu;
- Fu, Zheng;
- Zhao, Meng;
- Veerapen, Natacha;
- Richardson, Stewart K.;
- Porcelli, Steven A.;
- Besra, Gurdyal;
- Howell, Amy R.;
- Sharma, Sonia;
- Peters, Bjoern;
- Kronenberg, Mitchell
Publication type:
Article
Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner.
Published in:
Nature Immunology, 2012, v. 13, n. 1, p. 44, doi. 10.1038/ni.2172
By:
- King, Irah L;
- Fortier, Anne;
- Tighe, Michael;
- Dibble, John;
- Watts, Gerald F M;
- Veerapen, Natacha;
- Haberman, Ann M;
- Besra, Gurdyal S;
- Mohrs, Markus;
- Brenner, Michael B;
- Leadbetter, Elizabeth A
Publication type:
Article
Conserved allomorphs of MR1 drive the specificity of MR1-restricted TCRs.
Published in:
Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1419528
By:
- Cornforth, Terri V.;
- Moyo, Nathifa;
- Cole, Suzanne;
- Lam, Emily P. S.;
- Lobry, Tatiana;
- Wolchinsky, Ron;
- Lloyd, Angharad;
- Ward, Katarzyna;
- Denham, Eleanor M.;
- Masi, Giulia;
- Tea Qing Yun, Phyllis;
- Moore, Colin;
- Dhaouadi, Selsabil;
- Besra, Gurdyal S.;
- Veerapen, Natacha;
- Illing, Patricia T.;
- Vivian, Julian P.;
- Raynes, Jeremy M.;
- Nours, Jérôme Le;
- Purcell, Anthony W.
Publication type:
Article
The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis.
Published in:
Science Signaling, 2023, v. 16, n. 781, p. 1, doi. 10.1126/scisignal.abo2709
By:
- Kedia-Mehta, Nidhi;
- Pisarska, Marta M.;
- Rollings, Christina;
- O'Neill, Chloe;
- De Barra, Conor;
- Foley, Cathriona;
- Wood, Nicole A. W.;
- Wrigley-Kelly, Neil;
- Veerapen, Natacha;
- Besra, Gurdyal;
- Bergin, Ronan;
- Jones, Nicholas;
- O'Shea, Donal;
- Sinclair, Linda V.;
- Hogan, Andrew E.
Publication type:
Article
Identification of a Desaturase Involved in Mycolic Acid Biosynthesis in Mycobacterium smegmatis.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164253
By:
- Singh, Albel;
- Varela, Cristian;
- Bhatt, Kiranmai;
- Veerapen, Natacha;
- Lee, Oona Y. C.;
- Wu, Houdini H. T.;
- Besra, Gurdyal S.;
- Minnikin, David E.;
- Fujiwara, Nagatoshi;
- Teramoto, Kanae;
- Bhatt, Apoorva
Publication type:
Article
Recognition of Lyso-Phospholipids by Human Natural Killer T Lymphocytes.
Published in:
PLoS Biology, 2009, v. 7, n. 10, p. 1, doi. 10.1371/journal.pbio.1000228
By:
- Fox, Lisa M.;
- Cox, Daryl G.;
- Lockridge, Jennifer L.;
- Xiaohua Wang;
- Xiuxu Chen;
- Scharf, Louise;
- Trott, David L.;
- Ndonye, Rachel M.;
- Veerapen, Natacha;
- Besra, Gurdyal S.;
- Howell, Amy R.;
- Cook, Mark E.;
- Adams, Erin J.;
- Hildebrand, William H.;
- Gumperz, Jenny E.
Publication type:
Article
MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02540-x
By:
- Howson, Lauren J.;
- Napolitani, Giorgio;
- Shepherd, Dawn;
- Ghadbane, Hemza;
- Kurupati, Prathiba;
- Preciado-Llanes, Lorena;
- Rei, Margarida;
- Dobinson, Hazel C.;
- Gibani, Malick M.;
- Karen Wei Weng Teng;
- Newell, Evan W.;
- Veerapen, Natacha;
- Besra, Gurdyal S.;
- Pollard, Andrew J.;
- Cerundolo, Vincenzo
Publication type:
Article
Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31316-6
By:
- Richter, Adrian;
- Rudolph, Ines;
- Möllmann, Ute;
- Voigt, Kerstin;
- Chung, Chun-wa;
- Singh, Onkar M. P.;
- Rees, Michael;
- Mendoza-Losana, Alfonso;
- Bates, Robert;
- Ballell, Lluís;
- Batt, Sarah;
- Veerapen, Natacha;
- Fütterer, Klaus;
- Besra, Gurdyal;
- Imming, Peter;
- Argyrou, Argyrides
Publication type:
Article
Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2.
Published in:
Protein & Cell, 2020, v. 11, n. 7, p. 505, doi. 10.1007/s13238-020-00726-6
By:
- Zhang, Lu;
- Zhao, Yao;
- Gao, Ruogu;
- Li, Jun;
- Yang, Xiuna;
- Gao, Yan;
- Zhao, Wei;
- Gurcha, Sudagar S.;
- Veerapen, Natacha;
- Batt, Sarah M.;
- Besra, Kajelle Kaur;
- Xu, Wenqing;
- Bi, Lijun;
- Zhang, Xian'en;
- Guddat, Luke W.;
- Yang, Haitao;
- Wang, Quan;
- Besra, Gurdyal S.;
- Rao, Zihe
Publication type:
Article

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