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Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.
- Published in:
- Angewandte Chemie, 2017, v. 129, n. 49, p. 15761, doi. 10.1002/ange.201706788
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- Publication type:
- Article
Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.
- Published in:
- Angewandte Chemie International Edition, 2017, v. 56, n. 49, p. 15555, doi. 10.1002/anie.201706788
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- Publication type:
- Article
Structural basis of arginine asymmetrical dimethylation by PRMT6.
- Published in:
- Biochemical Journal, 2016, v. 473, n. 19, p. 3049, doi. 10.1042/BCJ20160537
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- Publication type:
- Article
Molecular basis for the methylation specificity of ATXR5 for histone H3.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. 11, p. 6375, doi. 10.1093/nar/gkx224
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- Publication type:
- Article
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
- Published in:
- Nucleic Acids Research, 2009, v. 37, n. 7, p. 2204, doi. 10.1093/nar/gkp086
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- Publication type:
- Article
Development of LM98, a Small‐Molecule TEAD Inhibitor Derived from Flufenamic Acid.
- Published in:
- ChemMedChem, 2021, v. 16, n. 19, p. 2982, doi. 10.1002/cmdc.202100432
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- Publication type:
- Article
Rational Design and Synthesis of Selective PRMT4 Inhibitors: A New Chemotype for Development of Cancer Therapeutics**.
- Published in:
- ChemMedChem, 2021, v. 16, n. 7, p. 1116, doi. 10.1002/cmdc.202100018
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- Publication type:
- Article
Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium.
- Published in:
- Nature Structural & Molecular Biology, 2010, v. 17, n. 5, p. 596, doi. 10.1038/nsmb.1795
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- Article
Erratum: L3MBTL1 recognition of mono- and dimethylated histones.
- Published in:
- 2008
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- Publication type:
- Correction Notice
L3MBTL1 recognition of mono- and dimethylated histones.
- Published in:
- Nature Structural & Molecular Biology, 2007, v. 14, n. 12, p. 1229, doi. 10.1038/nsmb1340
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- Publication type:
- Article
Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083737
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- Publication type:
- Article
Characterization of 14-3-3 Proteins from Cryptosporidium parvum.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0014827
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- Publication type:
- Article
Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2.
- Published in:
- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013559
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- Publication type:
- Article
Structural Biology of Human H3K9 Methyltransferases.
- Published in:
- PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008570
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- Publication type:
- Article
Structural Studies of a Four-MBT Repeat Protein MBTD1.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007274
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- Publication type:
- Article
Structural basis of allele variation of human thiopurine- S-methyltransferase.
- Published in:
- Proteins, 2007, v. 67, n. 1, p. 198, doi. 10.1002/prot.21272
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- Publication type:
- Article
Data mining crystallization databases: Knowledge-based approaches to optimize protein crystal screens.
- Published in:
- Proteins, 2003, v. 51, n. 4, p. 562, doi. 10.1002/prot.10340
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- Publication type:
- Article
A chemical toolbox for the study of bromodomains and epigenetic signaling.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09672-2
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- Publication type:
- Article
Structural basis for molecular recognition and presentation of histone H3 By WDR5.
- Published in:
- EMBO Journal, 2006, v. 25, n. 18, p. 4245, doi. 10.1038/sj.emboj.7601316
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- Publication type:
- Article
Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
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- Nature Communications, 2014, v. 5, n. 5, p. 3952, doi. 10.1038/ncomms4952
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- Publication type:
- Article
Thermal Denaturation Assays in Chemical Biology.
- Published in:
- Assay & Drug Development Technologies, 2012, v. 10, n. 2, p. 128, doi. 10.1089/adt.2011.0390
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- Publication type:
- Article
Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.
- Published in:
- Nature Chemical Biology, 2015, v. 11, n. 10, p. 815, doi. 10.1038/nchembio1015-815b
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- Publication type:
- Article
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.
- Published in:
- Nature Chemical Biology, 2015, v. 11, n. 8, p. 571, doi. 10.1038/nchembio.1859
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- Publication type:
- Article
Correction: Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases.
- Published in:
- 2007
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- Publication type:
- Correction Notice
Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases.
- Published in:
- PLoS Biology, 2007, v. 5, n. 5, p. e97, doi. 10.1371/journal.pbio.0050097
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- Publication type:
- Article
Mutated-γ-actin restores growth to a yeast amino acid transport defective mutant.
- Published in:
- Journal of Cellular Physiology, 2001, v. 186, n. 1, p. 124, doi. 10.1002/1097-4652(200101)186:1<124::AID-JCP1007>3.0.CO;2-Q
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- Publication type:
- Article
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.
- Published in:
- Nature, 2015, v. 525, n. 7568, p. 206, doi. 10.1038/nature15251
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- Publication type:
- Article
Analysis of binding site similarity, small-molecule similarity and experimental binding profiles in the human cytosolic sulfotransferase family.
- Published in:
- Bioinformatics, 2007, v. 23, n. 2, p. e104
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- Publication type:
- Article
Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
- Published in:
- Nucleic Acids Research, 2021, v. 49, n. 20, p. 11629, doi. 10.1093/nar/gkab460
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- Publication type:
- Article
The MLL1 trimeric catalytic complex is a dynamic conformational ensemble stabilized by multiple weak interactions.
- Published in:
- Nucleic Acids Research, 2019, v. 47, n. 17, p. 9433, doi. 10.1093/nar/gkz697
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- Publication type:
- Article
Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.
- Published in:
- FEBS Letters, 2013, v. 587, n. 23, p. 3859, doi. 10.1016/j.febslet.2013.10.020
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- Article
Protein production: feeding the crystallographers and NMR spectroscopists.
- Published in:
- Nature Structural Biology, 2000, v. 7, p. 970, doi. 10.1038/80751
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- Publication type:
- Article
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition.
- Published in:
- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05655-8
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- Publication type:
- Article
Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells.
- Published in:
- Clinical Epigenetics, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13148-015-0118-9
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- Publication type:
- Article
Inside Cover: A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a (ChemMedChem 3/2014).
- Published in:
- ChemMedChem, 2014, v. 9, n. 3, p. 414, doi. 10.1002/cmdc.201490006
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- Publication type:
- Article
A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a.
- Published in:
- ChemMedChem, 2014, v. 9, n. 3, p. 549, doi. 10.1002/cmdc.201300450
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- Publication type:
- Article
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.
- Published in:
- 2011
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- Publication type:
- Correction Notice
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.
- Published in:
- Nature Chemical Biology, 2011, v. 7, n. 8, p. 566, doi. 10.1038/nchembio.599
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- Publication type:
- Article
Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro.
- Published in:
- 2019
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- Publication type:
- Letter
Kinetic characterization of human mRNA guanine-N7 methyltransferase.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55184-5
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- Publication type:
- Article
Discovery of Nedd4 auto-ubiquitination inhibitors.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42997-z
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- Publication type:
- Article
Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
- Published in:
- Science Signaling, 2012, v. 5, n. 226, p. 1, doi. 10.1126/scisignal.2002979
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- Publication type:
- Article
Crystal structure of SARS‐CoV‐2 nsp10–nsp16 in complex with small molecule inhibitors, SS148 and WZ16.
- Published in:
- Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 9, p. 1, doi. 10.1002/pro.4395
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- Publication type:
- Article
Targeting human SET1/MLL family of proteins.
- Published in:
- Protein Science: A Publication of the Protein Society, 2017, v. 26, n. 4, p. 662, doi. 10.1002/pro.3129
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- Publication type:
- Article