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Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid-enriched milk formula by GC and MS/MS<sup>ALL</sup>.
Published in:
European Journal of Lipid Science & Technology, 2015, v. 117, n. 6, p. 751, doi. 10.1002/ejlt.201400575
By:
- Sokol, Elena;
- Ulven, Trond;
- Færgeman, Nils J.;
- Ejsing, Christer S.
Publication type:
Article
The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 3, p. 1, doi. 10.15252/emmm.201708047
By:
- Schilperoort, Maaike;
- Dam, Andrea D;
- Hoeke, Geerte;
- Shabalina, Irina G;
- Okolo, Anthony;
- Hanyaloglu, Aylin C;
- Dib, Lea H;
- Mol, Isabel M;
- Caengprasath, Natarin;
- Chan, Yi‐Wah;
- Damak, Sami;
- Miller, Anne Reifel;
- Coskun, Tamer;
- Shimpukade, Bharat;
- Ulven, Trond;
- Kooijman, Sander;
- Rensen, Patrick CN;
- Christian, Mark
Publication type:
Article
Leveraging amino acid sensors as therapeutic targets for tauopathies and related dementias: Molecular and cell biology: Tau‐related mechanisms.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043859
By:
- Lee, Daniel C.;
- Ma, Chao;
- Morgan, Dave;
- Liang, Huimin;
- Kovalenko, Andrii;
- Sandusky‐Beltran, Leslie A.;
- Calahatian, John Ivan;
- Kallupurackal, Mani;
- Hunt, Jerry B;
- Pandey, Shalini;
- Blazier, Danielle;
- Bickford, Paula;
- Michalski, Camilla;
- Fahnestock, Margaret;
- Pedersen, Daniel Sejer;
- Brauner‐Osborne, Hans;
- Ulven, Trond;
- Selenica, Maj‐Linda B.
Publication type:
Article
Structure‐Activity Relationship Explorations and Discovery of a Potent Antagonist for the Free Fatty Acid Receptor 2.
Published in:
ChemMedChem, 2021, v. 16, n. 21, p. 3326, doi. 10.1002/cmdc.202100356
By:
- Højgaard Hansen, Anders;
- Christensen, Henriette B.;
- Pandey, Sunil K.;
- Sergeev, Eugenia;
- Valentini, Alice;
- Dunlop, Julia;
- Dedeo, Domonkos;
- Fratta, Simone;
- Hudson, Brian D.;
- Milligan, Graeme;
- Ulven, Trond;
- Rexen Ulven, Elisabeth
Publication type:
Article
Discovery of GPR183 Agonists Based on an Antagonist Scaffold.
Published in:
ChemMedChem, 2021, v. 16, n. 17, p. 2623, doi. 10.1002/cmdc.202100301
By:
- Kjær, Viktoria M. S.;
- Ieremias, Loukas;
- Daugvilaite, Viktorija;
- Lückmann, Michael;
- Frimurer, Thomas M.;
- Ulven, Trond;
- Rosenkilde, Mette M.;
- Våbenø, Jon
Publication type:
Article
Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.
Published in:
Diabetologia, 2023, v. 66, n. 8, p. 1501, doi. 10.1007/s00125-023-05932-5
By:
- Lorza-Gil, Estela;
- Kaiser, Gabriele;
- Carlein, Christopher;
- Hoffmann, Markus D. A.;
- König, Gabriele M.;
- Haug, Sieglinde;
- Prates Roma, Leticia;
- Rexen Ulven, Elisabeth;
- Ulven, Trond;
- Kostenis, Evi;
- Birkenfeld, Andreas L.;
- Häring, Hans-Ulrich;
- Ullrich, Susanne;
- Gerst, Felicia
Publication type:
Article
PGH<sub>1</sub>, the Precursor for the Anti-Inflammatory Prostaglandins of the 1-series, Is a Potent Activator of the Pro-Inflammatory Receptor CRTH2/DP2.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033329
By:
- Schröder, Ralf;
- Luzheng Xue;
- Konya, Viktoria;
- Martini, Lene;
- Kampitsch, Nora;
- Whistler, Jennifer L.;
- Ulven, Trond;
- Heinemann, Akos;
- Pettipher, Roy;
- Kostenis, Evi
Publication type:
Article
Chemogenetics defines a short-chain fatty acid receptor gut--brain axis.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.73777
By:
- Barki, Natasja;
- Bolognini, Daniele;
- Börjesson, Ulf;
- Jenkins, Laura;
- Riddell, John;
- Hughes, David I.;
- Ulven, Trond;
- Hudson, Brian D.;
- Ulven, Elisabeth Rexen;
- Dekker, Niek;
- Tobin, Andrew B.;
- Milligan, Graeme
Publication type:
Article
A Method for the Selective Hydrolysis of Ketone Hydrazones in the Presence of Acetals.
Published in:
European Journal of Organic Chemistry, 2000, v. 2000, n. 24, p. 3971, doi. 10.1002/1099-0690(200012)2000:24<3971::AID-EJOC3971>3.0.CO;2-N
By:
- Ulven, Trond;
- Carlsen, Per H. J.
Publication type:
Article
Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance.
Published in:
FASEB Journal, 2017, v. 31, n. 5, p. 2195, doi. 10.1096/fj.201601248R
By:
- Houthuijzen, Julia M.;
- Oosterom, Ilse;
- Hudson, Brian D.;
- Akira Hirasawa;
- Daenen, Laura G. M.;
- McLean, Chelsea M.;
- Hansen, Steffen V. F.;
- van Jaarsveld, Marijn T. M.;
- Peeper, Daniel S.;
- Sadatmand, Sahar Jafari;
- Roodhart, Jeanine M. L.;
- van de Lest, Chris H. A.;
- Ulven, Trond;
- Kenji Ishihara;
- Milligan, Graeme;
- Voest, Emile E.
Publication type:
Article
Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs.
Published in:
FASEB Journal, 2012, v. 26, n. 12, p. 4951, doi. 10.1096/fj.12-213314
By:
- Hudson, Brian D.;
- Christiansen, Elisabeth;
- Tikhonova, Irina G.;
- Grundmann, Manuel;
- Kostenis, Evi;
- Adams, David R.;
- Ulven, Trond;
- Milligan, Graeme
Publication type:
Article
Drug Repurposing in Crohn's Disease Using Danish Real-World Data.
Published in:
Pragmatic & Observational Research, 2024, v. 15, p. 17, doi. 10.2147/POR.S444569
By:
- Shakibfar, Saeed;
- Allin, Kristine H;
- Jess, Tine;
- Barbieri, Maria Antonietta;
- Battini, Vera;
- Simoncic, Eva;
- Kirchgesner, Julien;
- Ulven, Trond;
- Sessa, Maurizio
Publication type:
Article
Selective Extraction of G-Quadruplex Ligands from a Rationally Designed Scaffold-Based Dynamic Combinatorial Library.
Published in:
Chemistry - A European Journal, 2008, v. 14, n. 31, p. 9487, doi. 10.1002/chem.200801109
By:
- Nielsen, Mads Corvinius;
- Ulven, Trond
Publication type:
Article
FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73467-5
By:
- Lorza-Gil, Estela;
- Kaiser, Gabriele;
- Rexen Ulven, Elisabeth;
- König, Gabriele M.;
- Gerst, Felicia;
- Oquendo, Morgana Barroso;
- Birkenfeld, Andreas L.;
- Häring, Hans-Ulrich;
- Kostenis, Evi;
- Ulven, Trond;
- Ullrich, Susanne
Publication type:
Article
Activation of GPR40 induces hypothalamic neurogenesis through p38- and BDNF-dependent mechanisms.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68110-2
By:
- Engel, Daiane F.;
- Bobbo, Vanessa C. D.;
- Solon, Carina S.;
- Nogueira, Guilherme A.;
- Moura-Assis, Alexandre;
- Mendes, Natalia F.;
- Zanesco, Ariane M.;
- Papangelis, Athanasios;
- Ulven, Trond;
- Velloso, Licio A.
Publication type:
Article
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization.
Published in:
Science Signaling, 2023, v. 16, n. 779, p. 1, doi. 10.1126/scisignal.abl4283
By:
- Kjær, Viktoria M. S.;
- Daugvilaite, Viktorija;
- Stepniewski, Tomasz M.;
- Madsen, Christian M.;
- Jørgensen, Astrid S.;
- Bhuskute, Kaustubh R.;
- Inoue, Asuka;
- Ulven, Trond;
- Benned-Jensen, Tau;
- Hjorth, Siv A.;
- Hjortø, Gertrud M.;
- Moo, Ee Von;
- Selent, Jana;
- Rosenkilde, Mette M.
Publication type:
Article
One‐Pot Synthesis of Xanthone by Carbonylative Suzuki Coupling Reaction.
Published in:
ChemistrySelect, 2021, v. 6, n. 18, p. 4511, doi. 10.1002/slct.202101394
By:
- Loureiro, Daniela R. P.;
- Soares, José X.;
- Maia, Ana;
- Silva, André M. N.;
- Rangel, Maria;
- Azevedo, Carlos M. G.;
- Hansen, Steffen V.;
- Ulven, Trond;
- Pinto, Madalena M. M.;
- Reis, Salette;
- Afonso, Carlos M. M.
Publication type:
Article
The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity.
Published in:
Journal of Innate Immunity, 2021, v. 13, n. 4, p. 242, doi. 10.1159/000514887
By:
- Mårtensson, Jonas;
- Sundqvist, Martina;
- Manandhar, Asmita;
- Ieremias, Loukas;
- Zhang, Linjie;
- Ulven, Trond;
- Xie, Xin;
- Björkman, Lena;
- Forsman, Huamei
Publication type:
Article
Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation.
Published in:
2017
By:
- Dragano, Nathalia R. V.;
- Solon, Carina;
- Ramalho, Albina F.;
- de Moura, Rodrigo F.;
- Razolli, Daniela S.;
- Christiansen, Elisabeth;
- Azevedo, Carlos;
- Ulven, Trond;
- Velloso, Licio A.
Publication type:
journal article
Pathophysiological regulation of lung function by the free fatty acid receptor FFA4.
Published in:
Science Translational Medicine, 2020, v. 12, n. 557, p. 1, doi. 10.1126/scitranslmed.aaw9009
By:
- Prihandoko, Rudi;
- Kaur, Davinder;
- Wiegman, Coen H.;
- Alvarez-Curto, Elisa;
- Donovan, Chantal;
- Chachi, Latifa;
- Ulven, Trond;
- Tyas, Martha R.;
- Euston, Eloise;
- Dong, Zhaoyang;
- Alharbi, Abdulrahman Ghali M.;
- Kim, Richard Y.;
- Lowe, Jack G.;
- Hansbro, Philip M.;
- Chung, Kian Fan;
- Brightling, Christopher E.;
- Milligan, Graeme;
- Tobin, Andrew B.
Publication type:
Article
A biased ligand for OXE-R uncouples G? and G?? signaling within a heterotrimer.
Published in:
Nature Chemical Biology, 2012, v. 8, n. 7, p. 631, doi. 10.1038/nchembio.962
By:
- Blättermann, Stefanie;
- Peters, Lucas;
- Ottersbach, Philipp Aaron;
- Bock, Andreas;
- Konya, Viktoria;
- Weaver, C David;
- Gonzalez, Angel;
- Schröder, Ralf;
- Tyagi, Rahul;
- Luschnig, Petra;
- Gäb, Jürgen;
- Hennen, Stephanie;
- Ulven, Trond;
- Pardo, Leonardo;
- Mohr, Klaus;
- Gütschow, Michael;
- Heinemann, Akos;
- Kostenis, Evi
Publication type:
Article
Multistep Continuous-Flow Synthesis in Medicinal Chemistry: Discovery and Preliminary Structure-Activity Relationships of CCR8 Ligands.
Published in:
Chemistry - A European Journal, 2013, v. 19, n. 28, p. 9343, doi. 10.1002/chem.201204350
By:
- Petersen, Trine P.;
- Mirsharghi, Sahar;
- Rummel, Pia C.;
- Thiele, Stefanie;
- Rosenkilde, Mette M.;
- Ritzén, Andreas;
- Ulven, Trond
Publication type:
Article
Tetrasubstituted Phenanthrolines as Highly Potent, Water-Soluble, and Selective G-Quadruplex Ligands.
Published in:
Chemistry - A European Journal, 2012, v. 18, n. 35, p. 10892, doi. 10.1002/chem.201200081
By:
- Larsen, Anders Foller;
- Nielsen, Mads Corvinius;
- Ulven, Trond
Publication type:
Article
Synthesis and Biological Evaluation of 12,13-Cyclopropyl and 12,13-Cyclobutyl Epothilones.
Published in:
ChemBioChem, 2001, v. 2, n. 1, p. 69, doi. 10.1002/1439-7633(20010105)2:1<69::AID-CBIC69>3.0.CO;2-8
By:
- Nicolaou, K. C.;
- Namoto, Kenji;
- Li, Jim;
- Ritzén, Andreas;
- Ulven, Trond;
- Shoji, Mitsuru;
- Zaharevitz, Dan;
- Gussio, Rick;
- Sackett, Dan L.;
- Ward, Rita D.;
- Hensler, Anne;
- Fojo, Tito;
- Giannakakou, Paraskevi
Publication type:
Article
Structure–activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor.
Published in:
Basic & Clinical Pharmacology & Toxicology, 2023, v. 132, n. 6, p. 459, doi. 10.1111/bcpt.13861
By:
- Deng, Yufang;
- Perez Almeria, Claudia V.;
- van Gijzel, Lieke;
- Schaller, Kay;
- Vedel, Line;
- Gloriam, David E.;
- Ulven, Trond;
- Bräuner‐Osborne, Hans
Publication type:
Article
Treatment of type 2 diabetes by free fatty acid receptor agonists.
Published in:
Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00137
By:
- Watterson1, Kenneth R.;
- Hudson1, Brian D.;
- Ulven, Trond;
- Milligan, Graeme
Publication type:
Article
Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets.
Published in:
Frontiers in Endocrinology, 2012, v. 3, p. 1, doi. 10.3389/fendo.2012.00111
By:
- Ulven, Trond
Publication type:
Article
Effects of Delayed-Release Olive Oil and Hydrolyzed Pine Nut Oil on Glucose Tolerance, Incretin Secretion and Appetite in Humans.
Published in:
Nutrients, 2021, v. 13, n. 10, p. 3407, doi. 10.3390/nu13103407
By:
- Sørensen, Karina V.;
- Kaspersen, Mads H.;
- Ekberg, Jeppe H.;
- Bauer-Brandl, Annette;
- Ulven, Trond;
- Højlund, Kurt
Publication type:
Article
The Oxygen-Mediated Synthesis of 1,3-Butadiynes in Continuous Flow: Using Teflon AF-2400 to Effect Gas/Liquid Contact.
Published in:
ChemSusChem, 2012, v. 5, n. 2, p. 274, doi. 10.1002/cssc.201100339
By:
- Petersen, Trine P.;
- Polyzos, Anastasios;
- O'Brien, Matthew;
- Ulven, Trond;
- Baxendale, Ian R.;
- Ley, Steven V.
Publication type:
Article
Reevaluation of fatty acid receptor 1 as a drug target for the stimulation of insulin secretion in humans.
Published in:
2013
By:
- Wagner, Robert;
- Kaiser, Gabriele;
- Gerst, Felicia;
- Christiansen, Elisabeth;
- Due-Hansen, Maria E;
- Grundmann, Manuel;
- Machicao, Fausto;
- Peter, Andreas;
- Kostenis, Evi;
- Ulven, Trond;
- Fritsche, Andreas;
- Häring, Hans-Ulrich;
- Ullrich, Susanne
Publication type:
journal article
Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans.
Published in:
Diabetes, 2013, v. 62, n. 6, p. 2106, doi. 10.2337/db12-1249
By:
- Wagner, Robert;
- Kaiser, Gabriele;
- Gerst, Felicia;
- Christiansen, Elisabeth;
- Due-Hansen, Maria E.;
- Grundmann, Manuel;
- Machicao, Fausto;
- Peter, Andreas;
- Kostenis, Evi;
- Ulven, Trond;
- Fritsche, Andreas;
- Häring, Hans-Ulrich;
- Ullrich, and Susanne
Publication type:
Article

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