Found: 21

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  • Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31866-4
    By:
    • Möhrmann, Lino;
    • Werner, Maximilian;
    • Oleś, Małgorzata;
    • Mock, Andreas;
    • Uhrig, Sebastian;
    • Jahn, Arne;
    • Kreutzfeldt, Simon;
    • Fröhlich, Martina;
    • Hutter, Barbara;
    • Paramasivam, Nagarajan;
    • Richter, Daniela;
    • Beck, Katja;
    • Winter, Ulrike;
    • Pfütze, Katrin;
    • Heilig, Christoph E.;
    • Teleanu, Veronica;
    • Lipka, Daniel B.;
    • Zapatka, Marc;
    • Hanf, Dorothea;
    • List, Catrin
    Publication type:
    Article

  • The genomic and transcriptional landscape of primary central nervous system lymphoma.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30050-y
    By:
    • Radke, Josefine;
    • Ishaque, Naveed;
    • Koll, Randi;
    • Gu, Zuguang;
    • Schumann, Elisa;
    • Sieverling, Lina;
    • Uhrig, Sebastian;
    • Hübschmann, Daniel;
    • Toprak, Umut H.;
    • López, Cristina;
    • Hostench, Xavier Pastor;
    • Borgoni, Simone;
    • Juraeva, Dilafruz;
    • Pritsch, Fabienne;
    • Paramasivam, Nagarajan;
    • Balasubramanian, Gnana Prakash;
    • Schlesner, Matthias;
    • Sahay, Shashwat;
    • Weniger, Marc;
    • Pehl, Debora
    Publication type:
    Article

  • Correction to: Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations.

    Published in:
    2022
    By:
    • Simon, Malte;
    • Mughal, Sadaf S.;
    • Horak, Peter;
    • Uhrig, Sebastian;
    • Buchloh, Jonas;
    • Aybey, Bogac;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Fröhling, Stefan;
    • Brors, Benedikt;
    • Imbusch, Charles D.
    Publication type:
    corrected article

  • Germline SDHB‐inactivating mutation in gastric spindle cell sarcoma.

    Published in:
    Genes, Chromosomes & Cancer, 2020, v. 59, n. 10, p. 601, doi. 10.1002/gcc.22876
    By:
    • Heilig, Christoph E.;
    • Horak, Peter;
    • Lipka, Daniel B.;
    • Mock, Andreas;
    • Uhrig, Sebastian;
    • Kreutzfeldt, Simon;
    • Richter, Susan;
    • Gieldon, Laura;
    • Fröhlich, Martina;
    • Hutter, Barbara;
    • Hübschmann, Daniel;
    • Teleanu, Veronica;
    • Schmier, Johann‐Wilhelm;
    • Philipzen, Johannes;
    • Beuthien‐Baumann, Bettina;
    • Schröck, Evelin;
    • Deimling, Andreas;
    • Bauer, Sebastian;
    • Heining, Christoph;
    • Mechtersheimer, Gunhild
    Publication type:
    Article

  • Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification.

    Published in:
    2024
    By:
    • Tretter, Celina;
    • de Andrade Krätzig, Niklas;
    • Pecoraro, Matteo;
    • Lange, Sebastian;
    • Seifert, Philipp;
    • von Frankenberg, Clara;
    • Untch, Johannes;
    • Zuleger, Gabriela;
    • Wilhelm, Mathias;
    • Zolg, Daniel P.;
    • Dreyer, Florian S.;
    • Bräunlein, Eva;
    • Engleitner, Thomas;
    • Uhrig, Sebastian;
    • Boxberg, Melanie;
    • Steiger, Katja;
    • Slotta-Huspenina, Julia;
    • Ochsenreither, Sebastian;
    • von Bubnoff, Nikolas;
    • Bauer, Sebastian
    Publication type:
    Correction Notice

  • Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39570-7
    By:
    • Tretter, Celina;
    • de Andrade Krätzig, Niklas;
    • Pecoraro, Matteo;
    • Lange, Sebastian;
    • Seifert, Philipp;
    • von Frankenberg, Clara;
    • Untch, Johannes;
    • Zuleger, Gabriela;
    • Wilhelm, Mathias;
    • Zolg, Daniel P.;
    • Dreyer, Florian S.;
    • Bräunlein, Eva;
    • Engleitner, Thomas;
    • Uhrig, Sebastian;
    • Boxberg, Melanie;
    • Steiger, Katja;
    • Slotta-Huspenina, Julia;
    • Ochsenreither, Sebastian;
    • von Bubnoff, Nikolas;
    • Bauer, Sebastian
    Publication type:
    Article

  • Defective homologous recombination DNA repair as therapeutic target in advanced chordoma.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09633-9
    By:
    • Gröschel, Stefan;
    • Hübschmann, Daniel;
    • Raimondi, Francesco;
    • Horak, Peter;
    • Warsow, Gregor;
    • Fröhlich, Martina;
    • Klink, Barbara;
    • Gieldon, Laura;
    • Hutter, Barbara;
    • Kleinheinz, Kortine;
    • Bonekamp, David;
    • Marschal, Oliver;
    • Chudasama, Priya;
    • Mika, Jagoda;
    • Groth, Marie;
    • Uhrig, Sebastian;
    • Krämer, Stephen;
    • Heining, Christoph;
    • Heilig, Christoph E.;
    • Richter, Daniela
    Publication type:
    Article

  • Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations.

    Published in:
    Journal of Translational Medicine, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12967-021-02858-7
    By:
    • Simon, Malte;
    • Mughal, Sadaf S.;
    • Horak, Peter;
    • Uhrig, Sebastian;
    • Buchloh, Jonas;
    • Aybey, Bogac;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Fröhling, Stefan;
    • Brors, Benedikt;
    • Imbusch, Charles D.
    Publication type:
    Article

  • Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations.

    Published in:
    2021
    By:
    • Simon, Malte;
    • Mughal, Sadaf S.;
    • Horak, Peter;
    • Uhrig, Sebastian;
    • Buchloh, Jonas;
    • Aybey, Bogac;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Fröhling, Stefan;
    • Brors, Benedikt;
    • Imbusch, Charles D.
    Publication type:
    journal article

  • Integrating proteomics into precision oncology.

    Published in:
    International Journal of Cancer, 2021, v. 148, n. 6, p. 1438, doi. 10.1002/ijc.33301
    By:
    • Wahjudi, Leonie W.;
    • Bernhardt, Stephan;
    • Abnaof, Khalid;
    • Horak, Peter;
    • Kreutzfeldt, Simon;
    • Heining, Christoph;
    • Borgoni, Simone;
    • Becki, Corinna;
    • Berg, Daniela;
    • Richter, Daniela;
    • Hutter, Barbara;
    • Uhrig, Sebastian;
    • Pfütze, Katrin;
    • Leichsenring, Jonas;
    • Glimm, Hanno;
    • Brors, Benedikt;
    • Kalle, Christof;
    • Stenzinger, Albrecht;
    • Korf, Ulrike;
    • Fröhling, Stefan
    Publication type:
    Article

  • Variant classification in precision oncology.

    Published in:
    International Journal of Cancer, 2019, v. 145, n. 11, p. 2996, doi. 10.1002/ijc.32358
    By:
    • Leichsenring, Jonas;
    • Horak, Peter;
    • Kreutzfeldt, Simon;
    • Heining, Christoph;
    • Christopoulos, Petros;
    • Volckmar, Anna‐Lena;
    • Neumann, Olaf;
    • Kirchner, Martina;
    • Ploeger, Carolin;
    • Budczies, Jan;
    • Heilig, Christoph E.;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Uhrig, Sebastian;
    • Kazdal, Daniel;
    • Allgäuer, Michael;
    • Harms, Alexander;
    • Rempel, Eugen;
    • Lehmann, Ulrich;
    • Thomas, Michael
    Publication type:
    Article

  • Precision oncology based on omics data: The NCT Heidelberg experience.

    Published in:
    International Journal of Cancer, 2017, v. 141, n. 5, p. 877, doi. 10.1002/ijc.30828
    By:
    • Horak, Peter;
    • Klink, Barbara;
    • Heining, Christoph;
    • Gröschel, Stefan;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Uhrig, Sebastian;
    • Hübschmann, Daniel;
    • Schlesner, Matthias;
    • Eils, Roland;
    • Richter, Daniela;
    • Pfütze, Katrin;
    • Geörg, Christina;
    • Meißburger, Bettina;
    • Wolf, Stephan;
    • Schulz, Angela;
    • Penzel, Roland;
    • Herpel, Esther;
    • Kirchner, Martina;
    • Lier, Amelie
    Publication type:
    Article

  • Prolonged Survival of a Patient with Advanced-Stage Combined Hepatocellular-Cholangiocarcinoma.

    Published in:
    Case Reports in Gastroenterology, 2020, v. 14, n. 3, p. 658, doi. 10.1159/000511034
    By:
    • Loosen, Sven H.;
    • Gaisa, Nadine T.;
    • Schmeding, Maximilian;
    • Heining, Christoph;
    • Uhrig, Sebastian;
    • Wirtz, Theresa H.;
    • Kalverkamp, Sebastian;
    • Spillner, Jan;
    • Tacke, Frank;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Fröhling, Stefan;
    • Trautwein, Christian;
    • Roderburg, Christoph;
    • Longerich, Thomas;
    • Neumann, Ulf Peter;
    • Luedde, Tom
    Publication type:
    Article

  • Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing.

    Published in:
    2022
    By:
    • Neumann, Olaf;
    • Burn, Timothy C.;
    • Allgäuer, Michael;
    • Ball, Markus;
    • Kirchner, Martina;
    • Albrecht, Thomas;
    • Volckmar, Anna-Lena;
    • Beck, Susanne;
    • Endris, Volker;
    • Goldschmid, Hannah;
    • Lehmann, Ulrich;
    • Seker-Cin, Huriye;
    • Uhrig, Sebastian;
    • Roessler, Stephanie;
    • Budczies, Jan;
    • Fröhling, Stefan;
    • Longerich, Thomas;
    • Wagner, Alex H.;
    • Vogel, Arndt;
    • Schirmacher, Peter
    Publication type:
    journal article

  • An optimized workflow to improve reliability of detection of KIAA1549:BRAF fusions from RNA sequencing data.

    Published in:
    Acta Neuropathologica, 2020, v. 140, n. 2, p. 237, doi. 10.1007/s00401-020-02167-1
    By:
    • Sommerkamp, Alexander C.;
    • Uhrig, Sebastian;
    • Stichel, Damian;
    • St-Onge, Pascal;
    • Sun, Pengbo;
    • Jäger, Natalie;
    • von Deimling, Andreas;
    • Sahm, Felix;
    • Pfister, Stefan M.;
    • Korshunov, Andrey;
    • Sinnett, Daniel;
    • Jabado, Nada;
    • Wefers, Annika K.;
    • Jones, David T. W.
    Publication type:
    Article

  • Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 2, p. 295, doi. 10.1007/s00401-019-02008-w
    By:
    • Paramasivam, Nagarajan;
    • Hübschmann, Daniel;
    • Toprak, Umut H;
    • Ishaque, Naveed;
    • Neidert, Marian;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David;
    • Sievers, Philipp;
    • Reinhardt, Annekathrin;
    • Wefers, Annika K.;
    • Jones, David T. W.;
    • Gu, Zuguang;
    • Werner, Johannes;
    • Uhrig, Sebastian;
    • Wirsching, Hans-Georg;
    • Schick, Matthias;
    • Bewerunge-Hudler, Melanie;
    • Beck, Katja;
    • Brehmer, Stephanie
    Publication type:
    Article

  • NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology.

    Published in:
    NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00458-w
    By:
    • Mock, Andreas;
    • Teleanu, Maria-Veronica;
    • Kreutzfeldt, Simon;
    • Heilig, Christoph E.;
    • Hüllein, Jennifer;
    • Möhrmann, Lino;
    • Jahn, Arne;
    • Hanf, Dorothea;
    • Kerle, Irina A.;
    • Singh, Hans Martin;
    • Hutter, Barbara;
    • Uhrig, Sebastian;
    • Fröhlich, Martina;
    • Neumann, Olaf;
    • Hartig, Andreas;
    • Brückmann, Sascha;
    • Hirsch, Steffen;
    • Grund, Kerstin;
    • Dikow, Nicola;
    • Lipka, Daniel B.
    Publication type:
    Article

  • Successful BRAF/MEK inhibition in a patient with BRAF<sup>V600E</sup>-mutated extrapancreatic acinar cell carcinoma.

    Published in:
    Cold Spring Harbor Molecular Case Studies, 2020, v. 6, n. 4, p. 1, doi. 10.1101/mcs.a005553
    By:
    • Busch, Elena;
    • Kreutzfeldt, Simon;
    • Agaimy, Abbas;
    • Mechtersheimer, Gunhild;
    • Horak, Peter;
    • Brors, Benedikt;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Uhrig, Sebastian;
    • Mayer, Philipp;
    • Schröck, Evelin;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Jäger, Dirk;
    • Springfeld, Christoph;
    • Fröhling, Stefan;
    • Zschäbitz, Stefanie
    Publication type:
    Article

  • PingPongPro: a tool for the detection of piRNA-mediated transposon-silencing in small RNA-Seq data.

    Published in:
    Bioinformatics, 2019, v. 35, n. 2, p. 335, doi. 10.1093/bioinformatics/bty578
    By:
    • Uhrig, Sebastian;
    • Klein, Holger
    Publication type:
    Article

  • MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18372-1
    By:
    • Munkhbaatar, Enkhtsetseg;
    • Dietzen, Michelle;
    • Agrawal, Deepti;
    • Anton, Martina;
    • Jesinghaus, Moritz;
    • Boxberg, Melanie;
    • Pfarr, Nicole;
    • Bidola, Pidassa;
    • Uhrig, Sebastian;
    • Höckendorf, Ulrike;
    • Meinhardt, Anna-Lena;
    • Wahida, Adam;
    • Heid, Irina;
    • Braren, Rickmer;
    • Mishra, Ritu;
    • Warth, Arne;
    • Muley, Thomas;
    • Poh, Patrina S. P.;
    • Wang, Xin;
    • Fröhling, Stefan
    Publication type:
    Article

  • The landscape of chromothripsis across adult cancer types.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16134-7
    By:
    • Voronina, Natalia;
    • Wong, John K. L.;
    • Hübschmann, Daniel;
    • Hlevnjak, Mario;
    • Uhrig, Sebastian;
    • Heilig, Christoph E.;
    • Horak, Peter;
    • Kreutzfeldt, Simon;
    • Mock, Andreas;
    • Stenzinger, Albrecht;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Brors, Benedikt;
    • Jahn, Arne;
    • Klink, Barbara;
    • Gieldon, Laura;
    • Sieverling, Lina;
    • Feuerbach, Lars;
    • Chudasama, Priya;
    • Beck, Katja
    Publication type:
    Article