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Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32630-4
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- Publication type:
- Article
Divergent roles of prostacyclin and PGE<sub>2</sub> in human tendinopathy.
- Published in:
- Arthritis Research & Therapy, 2019, v. 21, n. 1, p. N.PAG, doi. 10.1186/s13075-019-1855-5
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- Publication type:
- Article
Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family.
- Published in:
- BMC Structural Biology, 2012, v. 12, n. 1, p. 14, doi. 10.1186/1472-6807-12-14
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- Publication type:
- Article
Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits.
- Published in:
- Biochemical Journal, 2013, v. 452, n. 1, p. 27, doi. 10.1042/BJ20121580
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- Publication type:
- Article
Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 9, p. 1, doi. 10.1093/nar/gkw089
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- Publication type:
- Article
A homogeneous method for investigation of methylation-dependent protein–protein interactions in epigenetics.
- Published in:
- Nucleic Acids Research, 2010, v. 38, n. 2, p. e11, doi. 10.1093/nar/gkp899
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- Publication type:
- Article
Virtual Fragment Screening Identification of a Quinoline‐5,8‐dicarboxylic Acid Derivative as a Selective JMJD3 Inhibitor.
- Published in:
- ChemMedChem, 2018, v. 13, n. 12, p. 1160, doi. 10.1002/cmdc.201800198
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- Publication type:
- Article
Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq.
- Published in:
- Nature Biotechnology, 2021, v. 39, n. 12, p. 1517, doi. 10.1038/s41587-021-00965-w
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- Publication type:
- Article
Immune response to COVID‐19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T‐cell response.
- Published in:
- British Journal of Haematology, 2022, v. 197, n. 3, p. 293, doi. 10.1111/bjh.18066
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- Publication type:
- Article
Protein production and purification.
- Published in:
- Nature Methods, 2008, v. 5, n. 2, p. 135, doi. 10.1038/nmeth.f.202
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- Publication type:
- Article
Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study.
- Published in:
- 2020
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- Publication type:
- journal article
Bisphosphonates.
- Published in:
- Annals of the New York Academy of Sciences, 2007, v. 1117, p. 209, doi. 10.1196/annals.1402.089
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- Publication type:
- Article
Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases.
- Published in:
- Angewandte Chemie, 2012, v. 124, n. 7, p. 1663, doi. 10.1002/ange.201107833
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- Publication type:
- Article
The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47680-z
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- Publication type:
- Article
Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors.
- Published in:
- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0015535
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- Publication type:
- Article
High-Affinity Inhibitors of Human NAD<sup>+</sup>-Dependent 15- Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships.
- Published in:
- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013719
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- Publication type:
- Article
Structural Basis for Substrate Specificity in Human Monomeric Carbonyl Reductases.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007113
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- Publication type:
- Article
Crystal structure of human carbonic anhydrase-related protein VIII reveals the basis for catalytic silencing.
- Published in:
- Proteins, 2009, v. 76, n. 2, p. 507, doi. 10.1002/prot.22411
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- Publication type:
- Article
A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.
- Published in:
- 2016
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- Publication type:
- journal article
Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12711-7
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- Publication type:
- Article
Prospective Assessment of Tumour Burden and Bone Disease in Plasma Cell Dyscrasias Using DW-MRI and Exploratory Bone Biomarkers.
- Published in:
- Cancers, 2023, v. 15, n. 1, p. 95, doi. 10.3390/cancers15010095
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- Publication type:
- Article
SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target.
- Published in:
- Cancers, 2021, v. 13, n. 19, p. 4944, doi. 10.3390/cancers13194944
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- Publication type:
- Article
Determinants of durable humoral and T cell immunity in myeloma patients following COVID‐19 vaccination.
- Published in:
- European Journal of Haematology, 2024, v. 112, n. 4, p. 547, doi. 10.1111/ejh.14143
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- Publication type:
- Article
Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein.
- Published in:
- EMBO Journal, 2011, v. 30, n. 2, p. 317, doi. 10.1038/emboj.2010.311
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- Publication type:
- Article
Development and Application of a Fluoride-Detection-Based Fluorescence Assay for γ-Butyrobetaine Hydroxylase.
- Published in:
- ChemBioChem, 2012, v. 13, n. 11, p. 1559, doi. 10.1002/cbic.201200256
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- Publication type:
- Article
Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1.
- Published in:
- Molecules, 2022, v. 27, n. 3, p. 983, doi. 10.3390/molecules27030983
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- Publication type:
- Article
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
- Published in:
- Nature, 2007, v. 448, n. 7149, p. 87, doi. 10.1038/nature05971
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- Publication type:
- Article
Assessing histone demethylase inhibitors in cells: lessons learned.
- Published in:
- Epigenetics & Chromatin, 2017, v. 10, p. 1, doi. 10.1186/s13072-017-0116-6
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- Publication type:
- Article
H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis.
- Published in:
- Arthritis Research & Therapy, 2016, v. 18, p. 1, doi. 10.1186/s13075-016-1053-7
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- Publication type:
- Article
Why is epigenetics important in understanding the pathogenesis of infl ammatory musculoskeletal diseases?
- Published in:
- Arthritis Research & Therapy, 2013, v. 15, n. 2, p. 209, doi. 10.1186/ar4186
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- Publication type:
- Article
Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models.
- Published in:
- FEBS Journal, 2010, v. 277, n. 10, p. 2375, doi. 10.1111/j.1742-4658.2010.07656.x
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- Publication type:
- Article
Biochemical characterization of TASSELSEED 2, an essential plant short-chain dehydrogenase/reductase with broad spectrum activities.
- Published in:
- FEBS Journal, 2007, v. 274, n. 5, p. 1172, doi. 10.1111/j.1742-4658.2007.05642.x
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- Publication type:
- Article
Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding.
- Published in:
- Chemistry - A European Journal, 2019, v. 25, n. 8, p. 2019, doi. 10.1002/chem.201804790
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- Publication type:
- Article
Sclerostin expression in bone tumours and tumour-like lesions.
- Published in:
- Histopathology, 2016, v. 69, n. 3, p. 470, doi. 10.1111/his.12953
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- Publication type:
- Article
Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function.
- Published in:
- Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.626255
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- Publication type:
- Article
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.
- Published in:
- Nature Communications, 2016, v. 7, n. 9, p. 12700, doi. 10.1038/ncomms12700
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- Publication type:
- Article
Inflammation activation and resolution in human tendon disease.
- Published in:
- Science Translational Medicine, 2015, v. 7, n. 311, p. 1, doi. 10.1126/scitranslmed.aac4269
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- Publication type:
- Article
Evaluation of Micro-Parallel Liquid Chromatography as a Method for HTS-Coupled Actives Verification.
- Published in:
- Assay & Drug Development Technologies, 2007, v. 5, n. 6, p. 815, doi. 10.1089/adt.2007.097
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- Publication type:
- Article
A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency.
- Published in:
- Journal of Inherited Metabolic Disease, 2013, v. 36, n. 6, p. 983, doi. 10.1007/s10545-013-9589-z
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- Publication type:
- Article
High-throughput structural biology of metabolic enzymes and its impact on human diseases.
- Published in:
- Journal of Inherited Metabolic Disease, 2011, v. 34, n. 3, p. 575, doi. 10.1007/s10545-011-9296-6
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- Publication type:
- Article
Structural basis of fumarate hydratase deficiency.
- Published in:
- Journal of Inherited Metabolic Disease, 2011, v. 34, n. 3, p. 671, doi. 10.1007/s10545-011-9294-8
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- Publication type:
- Article
Interactive JIMD articles using the iSee concept: turning a new page on structural biology data.
- Published in:
- 2011
- By:
- Publication type:
- Editorial
Quinone Oxidoreductase-2-Mediated Prodrug Cancer Therapy.
- Published in:
- Science Translational Medicine, 2010, v. 2, n. 40, p. 1, doi. 10.1126/scitranslmed.3000615
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- Publication type:
- Article
Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
- Published in:
- PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0148762
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- Publication type:
- Article
Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin.
- Published in:
- Cellular & Molecular Life Sciences, 2011, v. 68, n. 6, p. 1065, doi. 10.1007/s00018-010-0508-2
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- Publication type:
- Article
Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
- Published in:
- Nature, 2014, v. 510, n. 7505, p. 422, doi. 10.1038/nature13263
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- Publication type:
- Article
Genetic Variants in <italic>ERAP1</italic> and <italic>ERAP2</italic> Associated With Immune‐Mediated Diseases Influence Protein Expression and the Isoform Profile.
- Published in:
- Arthritis & Rheumatology, 2018, v. 70, n. 2, p. 255, doi. 10.1002/art.40369
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- Publication type:
- Article
A novel INS mutation in a family with maturity‐onset diabetes of the young: Variable insulin secretion and putative mechanisms.
- Published in:
- Pediatric Diabetes, 2018, v. 19, n. 5, p. 905, doi. 10.1111/pedi.12679
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- Publication type:
- Article
Crystal structure of the PHF8 Jumonji domain, an N <sup>ε</sup>-methyl lysine demethylase
- Published in:
- FEBS Letters, 2010, v. 584, n. 4, p. 825, doi. 10.1016/j.febslet.2009.12.055
- By:
- Publication type:
- Article