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Lack of Cathepsin D in the central nervous system results in microglia and astrocyte activation and the accumulation of proteinopathy-related proteins.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15805-3
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- Publication type:
- Article
In-resin CLEM of Epon-embedded cells using proximity labeling.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15438-6
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- Publication type:
- Article
Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease.
- Published in:
- Journal of Gastroenterology, 2011, v. 46, n. 5, p. 629, doi. 10.1007/s00535-011-0390-1
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- Publication type:
- Article
Tumor endothelial cell autophagy is a key vascular‐immune checkpoint in melanoma.
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- EMBO Molecular Medicine, 2023, v. 15, n. 12, p. 1, doi. 10.15252/emmm.202318028
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- Publication type:
- Article
Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 155, doi. 10.3390/ijms21010155
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- Publication type:
- Article
Lack of Cathepsin D in the Renal Proximal Tubular Cells Resulted in Increased Sensitivity against Renal Ischemia/Reperfusion Injury.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1711, doi. 10.3390/ijms20071711
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- Publication type:
- Article
Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy.
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- Journal of Clinical Investigation, 2014, v. 124, n. 8, p. 3634, doi. 10.1172/JCI69866
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- Publication type:
- Article
Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice.
- Published in:
- 2010
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- Publication type:
- journal article
PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic Β cells.
- Published in:
- Journal of Clinical Investigation, 2005, v. 115, n. 1, p. 138, doi. 10.1172/JCI200522232
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- Publication type:
- Article
Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain.
- Published in:
- Glia, 2017, v. 65, n. 5, p. 727, doi. 10.1002/glia.23129
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- Publication type:
- Article
Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.
- Published in:
- Glia, 2010, v. 58, n. 1, p. 114, doi. 10.1002/glia.20906
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- Publication type:
- Article
Detection of a circadian enhancer in the mDbp promoter using prokaryotic transposon vector-based strategy.
- Published in:
- Nucleic Acids Research, 2008, v. 36, n. 4, p. e23, doi. 10.1093/nar/gkn018
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- Publication type:
- Article
RGS18 Acts as a Negative Regulator of Osteoclastogenesis by Modulating the Acid-Sensing OGR1INFAT Signaling Pathway.
- Published in:
- Journal of Bone & Mineral Research, 2007, v. 22, n. 10, p. 1612, doi. 10.1359/JBMR.070612
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- Publication type:
- Article
RANKL-Induced Expression of Tetraspanin CD9 in Lipid Raft Membrane Microdomain Is Essential for Cell Fusion During Osteoclastogenesis.
- Published in:
- Journal of Bone & Mineral Research, 2006, v. 21, n. 6, p. 965, doi. 10.1359/jbmr.060308
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- Publication type:
- Article
Presenilin 1 (PS1) is required for lysosome acidification: FAD mutations of PS1 cause loss of protein turnover by autophagy
- Published in:
- 2010
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- Publication type:
- Abstract
Haematopoietic development and immunological function in the absence of cathepsin D.
- Published in:
- BMC Immunology, 2007, v. 8, p. 22, doi. 10.1186/1471-2172-8-22
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- Publication type:
- Article
Immunohistochemical study of the autophagy marker microtubule-associated protein 1 light chain 3 in normal and steatotic human livers.
- Published in:
- Hepatology Research, 2014, v. 44, n. 7, p. 779, doi. 10.1111/hepr.12183
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- Publication type:
- Article
Macroautophagy -- a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease.
- Published in:
- Journal of Cell Biology, 2005, v. 171, n. 1, p. 87, doi. 10.1083/jcb.200505082
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- Publication type:
- Article
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.
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- Journal of Cell Biology, 2005, v. 169, n. 3, p. 425, doi. 10.1083/jcb.200412022
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- Publication type:
- Article
The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament...
- Published in:
- Journal of Cell Biology, 2003, v. 163, n. 5, p. 1021, doi. 10.1083/jcb.200308076
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- Publication type:
- Article
NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth.
- Published in:
- Journal of Cell Biology, 2003, v. 163, n. 5, p. 1011, doi. 10.1083/jcb.200308159
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- Publication type:
- Article
Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.
- Published in:
- Journal of Cell Biology, 2002, v. 158, n. 4, p. 681, doi. 10.1083/jcb.200202037
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- Publication type:
- Article
Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome.
- Published in:
- Scientific Reports, 2016, p. 37200, doi. 10.1038/srep37200
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- Publication type:
- Article
Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS.
- Published in:
- Scientific Reports, 2016, p. 34575, doi. 10.1038/srep34575
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- Publication type:
- Article
A Super-Ecliptic, pHluorin-mKate2, Tandem Fluorescent Protein-Tagged Human LC3 for the Monitoring of Mammalian Autophagy.
- Published in:
- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110600
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- Publication type:
- Article
Particle Size of Latex Beads Dictates IL-1β Production Mechanism.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068499
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- Publication type:
- Article
Enrichment of GABARAP Relative to LC3 in the Axonal Initial Segments of Neurons
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063568
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- Publication type:
- Article
Biogenesis and Proteolytic Processing of Lysosomal DNase II.
- Published in:
- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059148
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- Publication type:
- Article
Ablation of TSC2 Enhances Insulin Secretion by Increasing the Number of Mitochondria through Activation of mTORC1.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023238
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- Publication type:
- Article
Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines.
- Published in:
- PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009819
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- Publication type:
- Article
Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1<sup>H46R</sup>-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking.
- Published in:
- PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009805
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- Publication type:
- Article
Spatiotemporal expression of TRPM4 in the mouse cochlea.
- Published in:
- Journal of Neuroscience Research, 2014, v. 92, n. 10, p. 1409, doi. 10.1002/jnr.23410
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- Publication type:
- Article
Mammalian Mcm2/4/6/7 complex forms a toroidal structure.
- Published in:
- Genes to Cells, 2003, v. 8, n. 5, p. 413, doi. 10.1046/j.1365-2443.2003.00645.x
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- Publication type:
- Article
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis.
- Published in:
- Genes to Cells, 2002, v. 7, n. 6, p. 597, doi. 10.1046/j.1365-2443.2002.00539.x
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- Publication type:
- Article
GPHR‐mediated acidification of the Golgi lumen is essential for cholesterol biosynthesis in the brain.
- Published in:
- FEBS Letters, 2022, v. 596, n. 22, p. 2873, doi. 10.1002/1873-3468.14491
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- Publication type:
- Article
Caspase-9 Activation Revealed by Semaphorin 7A Cleavage Is Independent of Apoptosis in the Aged Olfactory Bulb.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 36, p. 11385, doi. 10.1523/JNEUROSCI.4780-08.2009
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- Publication type:
- Article
Phosphorylation of Highly Conserved Neurofilament Medium KSP Repeats Is Not Required for Myelin-Dependent Radial Axonal Growth.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 5, p. 1277, doi. 10.1523/JNEUROSCI.3765-08.2009
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- Publication type:
- Article
Developing Postmitotic Mammalian Neurons In Vivo Lacking Apaf-1 Undergo Programmed Cell Death by a Caspase-Independent, Nonapoptotic Pathway Involving Autophagy.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 6, p. 1490, doi. 10.1523/JNEUROSCI.4575-07.2008
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- Publication type:
- Article
Cathepsin D Deficiency Induces Persistent Neurodegeneration in the Absence of Bax-Dependent Apoptosis.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 8, p. 32, doi. 10.1523/JNEUROSCI.5577-06.2007
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- Publication type:
- Article
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK–ERK pathway to late endosomes.
- Published in:
- EMBO Journal, 2009, v. 28, n. 5, p. 477, doi. 10.1038/emboj.2008.308
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- Publication type:
- Article
C-terminal Src kinase controls development and maintenance of mouse squamous epithelia.
- Published in:
- EMBO Journal, 2007, v. 26, n. 5, p. 1234, doi. 10.1038/sj.emboj.7601595
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- Publication type:
- Article
L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2015, v. 35, n. 3, p. 382, doi. 10.1038/jcbfm.2014.210
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- Publication type:
- Article
Guidelines for cadaver dissection in education and research of clinical medicine (The Japan Surgical Society and The Japanese Association of Anatomists).
- Published in:
- Surgery Today, 2022, v. 52, n. 7, p. 989, doi. 10.1007/s00595-022-02525-4
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- Publication type:
- Article
Identification of Tim4 as a phosphatidylserine receptor.
- Published in:
- Nature, 2007, v. 450, n. 7168, p. 435, doi. 10.1038/nature06307
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- Publication type:
- Article
Loss of autophagy in the central nervous system causes neurodegeneration in mice.
- Published in:
- 2006
- By:
- Publication type:
- Letter
Golgi pH homeostasis stabilizes the lysosomal membrane through N-glycosylation of membrane proteins.
- Published in:
- Life Science Alliance, 2024, v. 7, n. 10, p. 1, doi. 10.26508/lsa.202402677
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- Publication type:
- Article
Renin–angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models.
- Published in:
- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-01483-2
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- Publication type:
- Article
Guidelines for cadaver dissection in education and research of clinical medicine (The Japan Surgical Society and The Japanese Association of Anatomists).
- Published in:
- Anatomical Science International, 2022, v. 97, n. 3, p. 235, doi. 10.1007/s12565-022-00665-8
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- Publication type:
- Article
Characterization of starvation-induced autophagy in cerebellar Purkinje cells of pHluorin-mKate2-human LC3B transgenic mice.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-66370-6
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- Publication type:
- Article
DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61287-6
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- Publication type:
- Article