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PROTAC-mediated conditional degradation of the WRN helicase as a potential strategy for selective killing of cancer cells with microsatellite instability.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-71160-5
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- Article
Functional characterization of C21ORF2 association with the NEK1 kinase mutated in human in diseases.
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- Life Science Alliance, 2023, v. 6, n. 7, p. 1, doi. 10.26508/lsa.202201740
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- Article
Structure-based design and characterization of Parkin-activating mutations.
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- Life Science Alliance, 2023, v. 6, n. 6, p. 1, doi. 10.26508/lsa.202201419
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- Article
Activity-based probe profiling of RNF12 E3 ubiquitin ligase function in Tonne-Kalscheuer syndrome.
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- Life Science Alliance, 2022, v. 5, n. 11, p. 1, doi. 10.26508/lsa.202101248
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- Article
Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28.
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- Cells (2073-4409), 2022, v. 11, n. 6, p. 1006, doi. 10.3390/cells11061006
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- Article
An RNF12-USP26 amplification loop drives germ cell specification and is disrupted by disease-associated mutations.
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- Science Signaling, 2022, v. 15, n. 742, p. 1, doi. 10.1126/scisignal.abm5995
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- Article
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
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- PLoS ONE, 2021, v. 16, n. 7, p. 1, doi. 10.1371/journal.pone.0253364
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- Article
MSK1 regulates transcriptional induction of Arc/Arg3.1 in response to neurotrophins.
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- FEBS Open Bio, 2017, v. 7, n. 6, p. 821, doi. 10.1002/2211-5463.12232
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- Article
ANIA: ANnotation and Integrated Analysis of the 14-3-3 interactome.
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- Database: The Journal of Biological Databases & Curation, 2014, v. 2014, p. 1, doi. 10.1093/database/bat085
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- Article
Correction: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
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- 2024
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- Correction Notice
Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells.
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- Biochemical Journal, 2022, v. 479, n. 16, p. 1709, doi. 10.1042/BCJ20220184
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- Article
An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
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- Biochemical Journal, 2021, v. 478, n. 23, p. 4119, doi. 10.1042/BCJ20210646
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- Article
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.
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- Biochemical Journal, 2021, v. 478, n. 3, p. 553, doi. 10.1042/BCJ20200937
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- Article
A complex comprising C15ORF41 and Codanin-1: the products of two genes mutated in congenital dyserythropoietic anaemia type I (CDA-I).
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- Biochemical Journal, 2020, v. 477, n. 10, p. 1893, doi. 10.1042/BCJ20190944
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- Article
PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.
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- Biochemical Journal, 2020, v. 477, n. 9, p. 1651, doi. 10.1042/BCJ20190664
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- Article
Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.
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- Biochemical Journal, 2017, v. 474, n. 4, p. 521, doi. 10.1042/BCJ20160646
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- Article
Assembly and structure of Lys<sup>33</sup>-linked polyubiquitin reveals distinct conformations.
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- Biochemical Journal, 2015, v. 467, n. 2, p. 345, doi. 10.1042/BJ20141502
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- Article
The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids.
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- eLife, 2016, p. 1, doi. 10.7554/eLife.12278
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- Article
Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases.
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- Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06787-w
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- Article
Characterization of FANCL variants observed in patient cancer cells.
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- Bioscience Reports, 2020, v. 40, n. 6, p. 1, doi. 10.1042/BSR20191304
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- Article
Improved Genome Editing in Human Cell Lines Using the CRISPR Method.
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- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109752
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- Article
Identification of the Amino Acids 300-600 of IRS-2 as 14-3-3 Binding Region with the Importance of IGF-1/Insulin-Regulated Phosphorylation of Ser- 573.
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- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043296
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- Article
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases.
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- EMBO Journal, 2011, v. 30, n. 9, p. 1730, doi. 10.1038/emboj.2011.78
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- Article
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.
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- EMBO Journal, 2004, v. 23, n. 4, p. 833, doi. 10.1038/sj.emboj.7600110
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- Article
Loss of iron triggers PINK1/Parkin-independent mitophagy.
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- EMBO Reports, 2013, v. 14, n. 12, p. 1127, doi. 10.1038/embor.2013.168
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- Article
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
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- Nature Immunology, 2008, v. 9, n. 9, p. 1028, doi. 10.1038/ni.1644
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- Article
Generation of a chemical genetic model for JAK3.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89356-4
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- Article
A novel RLIM/RNF12 variant disrupts protein stability and function to cause severe Tonne–Kalscheuer syndrome.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88911-3
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- Article
14-3-3-Pred: improved methods to predict 14-3-3-binding phosphopeptides.
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- Bioinformatics, 2015, v. 31, n. 14, p. 2276, doi. 10.1093/bioinformatics/btv133
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- Article
Improvement of the movement and host range properties of a plant virus vector through DNA shuffling.
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- Plant Journal, 2002, v. 30, n. 5, p. 593, doi. 10.1046/j.1365-313X.2002.01308.x
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- Article
Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage.
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- Nucleic Acids Research, 2007, v. 35, n. 16, p. 5312, doi. 10.1093/nar/gkm493
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- Article
Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-X<sub>L</sub>.
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- BMC Cell Biology, 2006, v. 7, p. 1, doi. 10.1186/1471-2121-7-1
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- Article
Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia.
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- Antioxidants, 2017, v. 6, n. 2, p. 27, doi. 10.3390/antiox6020027
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- Article
Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate
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- FEBS Letters, 2005, v. 579, n. 6, p. 1417, doi. 10.1016/j.febslet.2005.01.042
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- Article
CDKL5 kinase controls transcription‐coupled responses to DNA damage.
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- EMBO Journal, 2021, v. 40, n. 23, p. 1, doi. 10.15252/embj.2021108271
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- Article
Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase.
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- EMBO Journal, 2018, v. 37, n. 24, p. N.PAG, doi. 10.15252/embj.201899559
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- Article
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
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- EMBO Journal, 2015, v. 34, n. 20, p. 2506, doi. 10.15252/embj.201592337
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- Article
mTOR activates the VPS34- UVRAG complex to regulate autolysosomal tubulation and cell survival.
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- EMBO Journal, 2015, v. 34, n. 17, p. 2272, doi. 10.15252/embj.201590992
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- Article
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.
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- EMBO Journal, 2013, v. 32, n. 7, p. 1008, doi. 10.1038/emboj.2013.40
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- Article