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Liver X receptors in lipid metabolism: opportunities for drug discovery.
- Published in:
- Nature Reviews Drug Discovery, 2014, v. 13, n. 6, p. 433, doi. 10.1038/nrd4280
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- Publication type:
- Article
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors.
- Published in:
- Nature Medicine, 2003, v. 9, n. 2, p. 213, doi. 10.1038/nm820
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- Publication type:
- Article
PPAR-? dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation.
- Published in:
- Nature Medicine, 2001, v. 7, n. 1, p. 48, doi. 10.1038/83336
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- Publication type:
- Article
Activators of the nuclear receptor PPARγ enhance colon polyp formation.
- Published in:
- Nature Medicine, 1998, v. 4, n. 9, p. 1058, doi. 10.1038/2042
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- Publication type:
- Article
Arachidonic Acid Mobilization and Peroxidation Promote Microglial Dysfunction in Aβ Pathology.
- Published in:
- Journal of Neuroscience, 2024, v. 44, n. 31, p. 1, doi. 10.1523/JNEUROSCI.0202-24.2024
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- Publication type:
- Article
Leading by example: pastors, mentors, physician-scientists, and the ASCI.
- Published in:
- 2014
- By:
- Publication type:
- Speech
Coordinate regulation of neutrophil homeostasis by liver X receptors in mice.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 1, p. 337, doi. 10.1172/JCI58393
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- Publication type:
- Article
The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans.
- Published in:
- 2011
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- Publication type:
- journal article
LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression.
- Published in:
- 2010
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- Publication type:
- journal article
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE.
- Published in:
- 2007
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- Publication type:
- journal article
Ligand activation of LXRβ reverses atherosclerosis and cellular cholesterol overload in mice lacking LXRα and apoE.
- Published in:
- Journal of Clinical Investigation, 2007, v. 117, n. 8, p. 2337, doi. 10.1172/JCI31909
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- Publication type:
- Article
Liver X receptors as integrators of metabolic and inflammatory signaling.
- Published in:
- 2006
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- Publication type:
- journal article
PPARs in atherosclerosis: the clot thickens.
- Published in:
- Journal of Clinical Investigation, 2004, v. 114, n. 11, p. 1538, doi. 10.1172/JCI200423705
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- Publication type:
- Article
Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.28766
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- Publication type:
- Article
The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.29178
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- Publication type:
- Article
LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.08009
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- Publication type:
- Article
CRISPR/Cas9 based blockade of IL-10 signaling impairs lipid and tissue homeostasis to accelerate atherosclerosis.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.999470
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- Publication type:
- Article
USP20 links feeding-induced cholesterol synthesis and energy expenditure.
- Published in:
- SCIENCE CHINA Life Sciences, 2021, v. 64, n. 2, p. 337, doi. 10.1007/s11427-020-1867-8
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- Publication type:
- Article
NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism.
- Published in:
- Nature Medicine, 2006, v. 12, n. 9, p. 1048, doi. 10.1038/nm1471
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- Publication type:
- Article
Setting fat on fire.
- Published in:
- Nature Medicine, 2003, v. 9, n. 11, p. 1348, doi. 10.1038/nm1103-1348
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- Publication type:
- Article
Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.
- Published in:
- Nature Reviews Molecular Cell Biology, 2012, v. 13, n. 4, p. 213, doi. 10.1038/nrm3312
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- Publication type:
- Article
Orphan nuclear receptors find a home in the arterial wall.
- Published in:
- Current Atherosclerosis Reports, 2002, v. 4, n. 3, p. 213, doi. 10.1007/s11883-002-0022-6
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- Publication type:
- Article
Identification of a fat cell enhancer: Analysis of requirements for adipose tissue-specific gene expression.
- Published in:
- Journal of Cellular Biochemistry, 1992, v. 49, n. 3, p. 219, doi. 10.1002/jcb.240490303
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- Publication type:
- Article
In Search of Small Molecules That Selectively Inhibit MBOAT4.
- Published in:
- Molecules, 2021, v. 26, n. 24, p. 7599, doi. 10.3390/molecules26247599
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- Publication type:
- Article
Integration of metabolism and inflammation by lipid-activated nuclear receptors.
- Published in:
- Nature, 2008, v. 454, n. 7203, p. 470, doi. 10.1038/nature07202
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- Publication type:
- Article
Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses.
- Published in:
- Advanced Science, 2024, v. 11, n. 20, p. 1, doi. 10.1002/advs.202307201
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- Publication type:
- Article
Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle.
- Published in:
- 2021
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- Publication type:
- journal article
Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.
- Published in:
- 2019
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- Publication type:
- journal article
ER phospholipid composition modulates lipogenesis during feeding and in obesity.
- Published in:
- 2017
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- Publication type:
- journal article
RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs.
- Published in:
- 2017
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- Publication type:
- journal article
The nuclear receptor LXRα controls the functional specialization of splenic macrophages.
- Published in:
- Nature Immunology, 2013, v. 14, n. 8, p. 831, doi. 10.1038/ni.2622
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- Publication type:
- Article
Retinoid X receptor α attenuates host antiviral response by suppressing type I interferon.
- Published in:
- Nature Communications, 2014, v. 5, n. 11, p. 5494, doi. 10.1038/ncomms6494
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- Publication type:
- Article
MafB promotes atherosclerosis by inhibiting foam-cell apoptosis.
- Published in:
- Nature Communications, 2014, v. 5, n. 1, p. 3147, doi. 10.1038/ncomms4147
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- Publication type:
- Article
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 555, p. 1, doi. 10.1126/scitranslmed.aax8096
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- Publication type:
- Article
Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females.
- Published in:
- Science Translational Medicine, 2016, v. 8, n. 334, p. 1, doi. 10.1126/scitranslmed.aad3815
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- Publication type:
- Article
The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis.
- Published in:
- Science Translational Medicine, 2015, v. 7, n. 314, p. 1, doi. 10.1126/scitranslmed.aad1904
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- Publication type:
- Article
Palmoplantar Keratoderma along with Neuromuscular and Metabolic Phenotypes in Slurp1-Deficient Mice.
- Published in:
- Journal of Investigative Dermatology, 2014, v. 134, n. 6, p. 1589, doi. 10.1038/jid.2014.19
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- Publication type:
- Article
PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity.
- Published in:
- Antioxidants, 2019, v. 8, n. 1, p. 19, doi. 10.3390/antiox8010019
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- Publication type:
- Article
NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95720-1
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- Publication type:
- Article
Genome-Wide Association Studies Identify New Targets in Cardiovascular Disease.
- Published in:
- Science Translational Medicine, 2010, v. 2, n. 48, p. 1, doi. 10.1126/scitranslmed.3001557
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- Publication type:
- Article
Small Molecule-Induced Complement Factor D (Adipsin) Promotes Lipid Accumulation and Adipocyte Differentiation.
- Published in:
- PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0162228
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- Publication type:
- Article
LXR Deficiency Confers Increased Protection against Visceral Leishmania Infection in Mice.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 11, p. 1, doi. 10.1371/journal.pntd.0000886
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- Publication type:
- Article
LXR Deficiency Confers Increased Protection against Visceral Leishmania Infection in Mice.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 11, p. 1, doi. 10.1371/journal.pntd.0000886
- By:
- Publication type:
- Article
T0901317, an LXR agonist, augments PKA-induced vascular cell calcification
- Published in:
- FEBS Letters, 2009, v. 583, n. 8, p. 1344, doi. 10.1016/j.febslet.2009.03.039
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- Publication type:
- Article
The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 5, p. 1, doi. 10.1371/journal.pgen.1002709
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- Publication type:
- Article
Transcription factor PATZ1 promotes adipogenesis by controlling promoter regulatory loci of adipogenic factors.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52917-y
- By:
- Publication type:
- Article
Of Vitruvian mice and men
- Published in:
- 2008
- By:
- Publication type:
- Editorial
Phosphorylation of the liver X receptors
- Published in:
- FEBS Letters, 2006, v. 580, n. 20, p. 4835, doi. 10.1016/j.febslet.2006.07.074
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- Publication type:
- Article
Metabolism: Drug discovery goes for a swim.
- Published in:
- Nature Chemical Biology, 2013, v. 9, n. 2, p. 68, doi. 10.1038/nchembio.1167
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- Publication type:
- Article
Erratum. Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome. Diabetes 2022;71:2256-2271.
- Published in:
- 2023
- By:
- Publication type:
- Correction Notice