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GeneXpert MTB/RIF Ultra vs Unstimulated Interferon γ (IRISA-TB) for the Diagnosis of Tuberculous Pericarditis in a Tuberculosis-Endemic Setting.
Published in:
Open Forum Infectious Diseases, 2024, v. 11, n. 3, p. 1, doi. 10.1093/ofid/ofae021
By:
- Randall, Philippa;
- Esmail, Aliasgar;
- Wilson, Lindsay;
- Makambwa, Edson;
- Pooran, Anil;
- Tomasicchio, Michele;
- Dheda, Keertan;
- Ntsekhe, Mpiko
Publication type:
Article
The diagnostic accuracy of the MTBDRplus and MTBDRsl assays for drug-resistant TB detection when performed on sputum and culture isolates.
Published in:
Scientific Reports, 2016, p. 17850, doi. 10.1038/srep17850
By:
- Tomasicchio, Michele;
- Theron, Grant;
- Pietersen, Elize;
- Streicher, Elizabeth;
- Stanley-Josephs, Danielle;
- van Helden, Paul;
- Warren, Rob;
- Dheda, Keertan
Publication type:
Article
The Progestin-Only Contraceptive Medroxyprogesterone Acetate, but Not Norethisterone Acetate, Enhances HIV-1 Vpr-Mediated Apoptosis in Human CD4<sup>+</sup> T Cells through the Glucocorticoid Receptor
Published in:
PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062895
By:
- Tomasicchio, Michele;
- Avenant, Chanel;
- Du Toit, Andrea;
- Ray, Roslyn M.;
- Hapgood, Janet P.
Publication type:
Article
SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2024, v. 209, n. 7, p. 840, doi. 10.1164/rccm.202308-1438OC
By:
- Tomasicchio, Michele;
- Jaumdally, Shameem;
- Wilson, Lindsay;
- Kotze, Andrea;
- Semple, Lynn;
- Meier, Stuart;
- Pooran, Anil;
- Esmail, Aliasgar;
- Pillay, Komala;
- Roberts, Riyaadh;
- Kriel, Raymond;
- Meldau, Richard;
- Oelofse, Suzette;
- Mandviwala, Carley;
- Burns, Jessica;
- Londt, Rolanda;
- Davids, Malika;
- van der Merwe, Charnay;
- Roomaney, Aqeedah;
- Kühn, Louié
Publication type:
Article
An All-Oral 6-Month Regimen for Multidrug-Resistant Tuberculosis: A Multicenter, Randomized Controlled Clinical Trial (the NExT Study).
Published in:
2022
By:
- Esmail, Aliasgar;
- Oelofse, Suzette;
- Lombard, Carl;
- Perumal, Rubeshan;
- Mbuthini, Linda;
- Mahomed, Akhter Goolam;
- Variava, Ebrahim;
- Black, John;
- Oluboyo, Patrick;
- Gwentshu, Nelile;
- Ngam, Eric;
- Ackerman, Tertius;
- Marais, Linde;
- Mottay, Lynelle;
- Meier, Stuart;
- Pooran, Anil;
- Tomasicchio, Michele;
- Riele, Julian Te;
- Derendinger, Brigitta;
- Ndjeka, Norbert
Publication type:
journal article
A Human Lung Challenge Model to Evaluate the Safety and Immunogenicity of PPD and Live Bacillus Calmette-Guérin.
Published in:
2020
By:
- Davids, Malika;
- Pooran, Anil;
- Hermann, Clemens;
- Mottay, Lynelle;
- Thompson, Fawziyah;
- Cardenas, Jacob;
- Thearith, Jinghua Gu;
- Meldau, Richard;
- Limberis, Jason;
- Gina, Phindile;
- Srivastava, Shashikant;
- Calder, Bridget;
- Esmail, Aliasgar;
- Tomasicchio, Michele;
- Blackburn, Jonathan;
- Gumbo, Tawanda;
- Dheda, Keertan;
- Gu, Jinghua;
- Koeuth, Thearith
Publication type:
journal article
A human lung challenge model to evaluate the safety and immunogenicity of PPD and live BCG.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2020, v. 201, n. 10, p. E1
By:
- Pooran, Anil;
- Hermann, Clemens;
- Mottay, Lynelle;
- Thompson, Fawziyah;
- Cardenas, Jacob;
- Jinghua Gu;
- Koeuth, Thearith;
- Meldau, Richard;
- Limberis, Jason;
- Gina, Phindile;
- Srivastava, Shashikant;
- Calder, Bridget;
- Esmail, Aliasgar;
- Tomasicchio, Michele;
- Blackburn, Jonathan;
- Gumbo, Tawanda;
- Dheda, Keertan
Publication type:
Article
An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells.
Published in:
Cancer Immunology, Immunotherapy, 2019, v. 68, n. 1, p. 71, doi. 10.1007/s00262-018-2238-5
By:
- Tomasicchio, Michele;
- Semple, Lynn;
- Esmail, Aliasgar;
- Meldau, Richard;
- Randall, Philippa;
- Pooran, Anil;
- Davids, Malika;
- Cairncross, Lydia;
- Anderson, David;
- Downs, Jennifer;
- Malherbe, Francois;
- Novitzky, Nicolas;
- Panieri, Eugenio;
- Oelofse, Suzette;
- Londt, Rolanda;
- Naiker, Thurandrie;
- Dheda, Keertan
Publication type:
Article
The Frequency and Effect of Granulocytic Myeloid-Derived Suppressor Cells on Mycobacterial Survival in Patients With Tuberculosis: A Preliminary Report.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.676679
By:
- Davids, Malika;
- Pooran, Anil;
- Smith, Liezel;
- Tomasicchio, Michele;
- Dheda, Keertan
Publication type:
Article
Intensive Care Unit Sluice Room Sinks as Reservoirs and Sources of Potential Transmission of Carbapenem-Resistant Bacteria in a South African Tertiary Care Hospital.
Published in:
Infection & Drug Resistance, 2023, v. 16, p. 5427, doi. 10.2147/IDR.S418620
By:
- Dheda, Khelan R;
- Centner, Chad M;
- Wilson, Lindsay;
- Pooran, Anil;
- Grimwood, Shireen;
- Ghebrekristos, Yonas T;
- Oelofse, Suzette;
- Joubert, Ivan A;
- Esmail, Aliasgar;
- Tomasicchio, Michele
Publication type:
Article
Increased HIV‐1 infection in PBMCs treated in vitro with menstrual cycle phase hormones or medroxyprogesterone acetate likely occurs via different mechanisms.
Published in:
American Journal of Reproductive Immunology, 2022, v. 88, n. 6, p. 1, doi. 10.1111/aji.13643
By:
- Bick, Alexis J.;
- Avenant, Chanel;
- Tomasicchio, Michele;
- van der Spuy, Zephne;
- Hapgood, Janet P.
Publication type:
Article
Modulation of HIV-1 virulence via the host glucocorticoid receptor: towards further understanding the molecular mechanisms of HIV-1 pathogenesis.
Published in:
Archives of Virology, 2010, v. 155, n. 7, p. 1009, doi. 10.1007/s00705-010-0678-0
By:
- Hapgood, Janet Patricia;
- Tomasicchio, Michele
Publication type:
Article
Differential Glucocorticoid Receptor-Mediated Effects on Immunomodulatory Gene Expression by Progestin Contraceptives: Implications for HIV-1 Pathogenesis.
Published in:
American Journal of Reproductive Immunology, 2014, v. 71, n. 6, p. 505, doi. 10.1111/aji.12214
By:
- Hapgood, Janet P.;
- Ray, Roslyn M.;
- Govender, Yashini;
- Avenant, Chanel;
- Tomasicchio, Michele
Publication type:
Article
The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis-Specific Host Immunity Through the Glucocorticoid Receptor.
Published in:
2019
By:
- Tomasicchio, Michele;
- Davids, Malika;
- Pooran, Anil;
- Theron, Grant;
- Smith, Liezel;
- Semple, Lynn;
- Meldau, Richard;
- Hapgood, Janet Patricia;
- Dheda, Keertan
Publication type:
journal article
Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels.
Published in:
PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0196043
By:
- Maritz, Michelle F.;
- Ray, Roslyn M.;
- Bick, Alexis J.;
- Tomasicchio, Michele;
- Woodland, John G.;
- Govender, Yashini;
- Avenant, Chanel;
- Hapgood, Janet P.
Publication type:
Article

Found: 15