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Mendelian gene identification through mouse embryo viability screening.
Published in:
Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01118-7
By:
- Cacheiro, Pilar;
- Westerberg, Carl Henrik;
- Mager, Jesse;
- Dickinson, Mary E.;
- Nutter, Lauryl M. J.;
- Muñoz-Fuentes, Violeta;
- Hsu, Chih-Wei;
- Van den Veyver, Ignatia B.;
- Flenniken, Ann M.;
- McKerlie, Colin;
- Murray, Stephen A.;
- Teboul, Lydia;
- Heaney, Jason D.;
- Lloyd, K. C. Kent;
- Lanoue, Louise;
- Braun, Robert E.;
- White, Jacqueline K.;
- Creighton, Amie K.;
- Laurin, Valerie;
- Guo, Ruolin
Publication type:
Article
Overexpression of Fto leads to increased food intake and results in obesity.
Published in:
Nature Genetics, 2010, v. 42, n. 12, p. 1086, doi. 10.1038/ng.713
By:
- Church, Chris;
- Moir, Lee;
- McMurray, Fiona;
- Girard, Christophe;
- Banks, Gareth T.;
- Teboul, Lydia;
- Wells, Sara;
- Brüning, Jens C.;
- Nolan, Patrick M.;
- Ashcroft, Frances M.;
- Cox, Roger D.
Publication type:
Article
Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-72418-8
By:
- Elrick, Hillary;
- Peterson, Kevin A.;
- Willis, Brandon J.;
- Lanza, Denise G.;
- Acar, Elif F.;
- Ryder, Edward J.;
- Teboul, Lydia;
- Kasparek, Petr;
- Birling, Marie-Christine;
- Adams, David J.;
- Bradley, Allan;
- Braun, Robert E.;
- Brown, Steve D.;
- Caulder, Adam;
- Codner, Gemma F.;
- DeMayo, Francesco J.;
- Dickinson, Mary E.;
- Doe, Brendan;
- Duddy, Graham;
- Gertsenstein, Marina
Publication type:
Article
NAADP mobilizes calcium from acidic organelles through two-pore channels.
Published in:
Nature, 2009, v. 459, n. 7246, p. 596, doi. 10.1038/nature08030
By:
- Calcraft, Peter J.;
- Ruas, Margarida;
- Pan, Zui;
- Cheng, Xiaotong;
- Arredouani, Abdelilah;
- Hao, Xuemei;
- Tang, Jisen;
- Rietdorf, Katja;
- Teboul, Lydia;
- Chuang, Kai-Ting;
- Lin, Peihui;
- Xiao, Rui;
- Wang, Chunbo;
- Zhu, Yingmin;
- Lin, Yakang;
- Wyatt, Christopher N.;
- Parrington, John;
- Ma, Jianjie;
- Evans, A. Mark;
- Galione, Antony
Publication type:
Article
Male mice lacking ADAMTS-16 are fertile but exhibit testes of reduced weight.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-53900-0
By:
- Livermore, Catherine;
- Warr, Nick;
- Chalon, Nicolas;
- Siggers, Pam;
- Mianné, Joffrey;
- Codner, Gemma;
- Teboul, Lydia;
- Wells, Sara;
- Greenfield, Andy
Publication type:
Article
Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout.
Published in:
FASEB Journal, 2023, v. 37, n. 11, p. 1, doi. 10.1096/fj.202201918R
By:
- Bai, Ying;
- Bentley, Liz;
- Ma, Chao;
- Naveenan, Navaratnam;
- Cleak, James;
- Wu, Yixing;
- Simon, Michelle M.;
- Westerberg, Henrik;
- Cañas, Ramón Casero;
- Horner, Neil;
- Pandey, Rajesh;
- Paphiti, Keanu;
- Schulze, Ulrike;
- Mianné, Joffrey;
- Hough, Tertius;
- Teboul, Lydia;
- de Baaij, Jeroen H. F.;
- Cox, Roger D.
Publication type:
Article
Long-read sequencing for fast and robust identification of correct genome-edited alleles: PCR-based and Cas9 capture methods.
Published in:
PLoS Genetics, 2024, v. 20, n. 3, p. 1, doi. 10.1371/journal.pgen.1011187
By:
- McCabe, Christopher V.;
- Price, Peter D.;
- Codner, Gemma F.;
- Allan, Alasdair J.;
- Caulder, Adam;
- Christou, Skevoulla;
- Loeffler, Jorik;
- Mackenzie, Matthew;
- Malzer, Elke;
- Mianné, Joffrey;
- Nowicki, Krystian J.;
- O'Neill, Edward J.;
- Pike, Fran J.;
- Hutchison, Marie;
- Petit-Demoulière, Benoit;
- Stewart, Michelle E.;
- Gates, Hilary;
- Wells, Sara;
- Sanderson, Nicholas D.;
- Teboul, Lydia
Publication type:
Article
A bioimage informatics platform for high-throughput embryo phenotyping.
Published in:
Briefings in Bioinformatics, 2018, v. 19, n. 1, p. 41, doi. 10.1093/bib/bbw101
By:
- Brown, James M;
- Horner, Neil R;
- Lawson, Thomas N;
- Fiegel, Tanja;
- Greenaway, Simon;
- Morgan, Hugh;
- Ring, Natalie;
- Santos, Luis;
- Sneddon, Duncan;
- Teboul, Lydia
Publication type:
Article
Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.
Published in:
Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-016-1012-2
By:
- Haeussler, Maximilian;
- Schönig, Kai;
- Eckert, Hélène;
- Eschstruth, Alexis;
- Mianné, Joffrey;
- Renaud, Jean-Baptiste;
- Schneider-Maunoury, Sylvie;
- Shkumatava, Alena;
- Teboul, Lydia;
- Kent, Jim;
- Joly, Jean-Stephane;
- Concordet, Jean-Paul
Publication type:
Article
Ap2s1 mutation causes hypercalcaemia in mice and impairs interaction between calcium-sensing receptor and adaptor protein-2.
Published in:
Human Molecular Genetics, 2021, v. 30, n. 10, p. 880, doi. 10.1093/hmg/ddab076
By:
- Hannan, Fadil M;
- Stevenson, Mark;
- Bayliss, Asha L;
- Stokes, Victoria J;
- Stewart, Michelle;
- Kooblall, Kreepa G;
- Gorvin, Caroline M;
- Codner, Gemma;
- Teboul, Lydia;
- Wells, Sara;
- Thakker, Rajesh V
Publication type:
Article
Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 2, p. 291, doi. 10.1093/hmg/ddv471
By:
- Joyce, Peter I.;
- Fratta, Pietro;
- Landman, Allison S.;
- Mcgoldrick, Philip;
- Wackerhage, Henning;
- Groves, Michael;
- Busam, Bharani Shiva;
- Galino, Jorge;
- Corrochano, Silvia;
- Beskina, Olga A.;
- Esapa, Christopher;
- Ryder, Edward;
- Carter, Sarah;
- Stewart, Michelle;
- Codner, Gemma;
- Hilton, Helen;
- Teboul, Lydia;
- Tucker, Jennifer;
- Lionikas, Arimantas;
- Estabel, Jeanne
Publication type:
Article
Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 11, p. 3035, doi. 10.1093/hmg/ddu020
By:
- Warr, Nick;
- Siggers, Pam;
- Carré, Gwenn-Aël;
- Bogani, Debora;
- Brixey, Rachel;
- Akiyoshi, Mika;
- Tachibana, Makoto;
- Teboul, Lydia;
- Wells, Sara;
- Sanderson, Jeremy;
- Greenfield, Andy
Publication type:
Article
Introduction to Mammalian Genome Special Issue: Mammalian Genetic Resources.
Published in:
2022
By:
- Brown, Steve D. M.;
- Nadeau, Joseph H.;
- Wells, Sara;
- Mallon, Ann-Marie;
- Teboul, Lydia;
- Tuggle, Christopher K.;
- Schook, Lawrence B.
Publication type:
Editorial
A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits.
Published in:
Mammalian Genome, 2021, v. 32, n. 2, p. 94, doi. 10.1007/s00335-021-09864-6
By:
- Cleverley, Karen;
- Lee, Weaverly Colleen;
- Mumford, Paige;
- Collins, Toby;
- Rickman, Matthew;
- Cunningham, Thomas J.;
- Cleak, James;
- Mianne, Joffrey;
- Szoke-Kovacs, Zsombor;
- Stewart, Michelle;
- Teboul, Lydia;
- Maduro, Cheryl;
- Wells, Sara;
- Wiseman, Frances K.;
- Fisher, Elizabeth M. C.
Publication type:
Article
Introduction to Mammalian Genome Special Issue: Genome Editing.
Published in:
2017
By:
- Teboul, Lydia;
- Hérault, Yann;
- Smith, Cynthia;
- Whitelaw, Bruce
Publication type:
Editorial
Phenotyping first-generation genome editing mutants: a new standard?
Published in:
Mammalian Genome, 2017, v. 28, n. 7/8, p. 377, doi. 10.1007/s00335-017-9711-x
By:
- Teboul, Lydia;
- Murray, Stephen;
- Nolan, Patrick
Publication type:
Article
Microhomologies are prevalent at Cas9-induced larger deletions.
Published in:
Nucleic Acids Research, 2019, v. 47, n. 14, p. 7402, doi. 10.1093/nar/gkz459
By:
- Owens, Dominic D G;
- Caulder, Adam;
- Frontera, Vincent;
- Harman, Joe R;
- Allan, Alasdair J;
- Bucakci, Akin;
- Greder, Lucas;
- Codner, Gemma F;
- Hublitz, Philip;
- McHugh, Peter J;
- Teboul, Lydia;
- de Bruijn, Marella F T R
Publication type:
Article
Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction.
Published in:
BMC Cell Biology, 2016, v. 17, p. 1, doi. 10.1186/s12860-016-0108-6
By:
- Codner, Gemma F.;
- Lindner, Loic;
- Caulder, Adam;
- Wattenhofer-Donzé, Marie;
- Radage, Adam;
- Mertz, Annelyse;
- Eisenmann, Benjamin;
- Mianné, Joffrey;
- Evans, Edward P.;
- Beechey, Colin V.;
- Fray, Martin D.;
- Birling, Marie-Christine;
- Hérault, Yann;
- Pavlovic, Guillaume;
- Teboul, Lydia
Publication type:
Article
How much do we know about the function of mammalian genes?
Published in:
BMC Biology, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12915-023-01794-w
By:
- Teboul, Lydia;
- Hérault, Yann;
- Wells, Sara;
- Pavlovic, Guillaume
Publication type:
Article
Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse.
Published in:
PLoS Genetics, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pgen.1003166
By:
- McMurray, Fiona;
- Church, Chris D.;
- Larder, Rachel;
- Nicholson, George;
- Wells, Sara;
- Teboul, Lydia;
- Tung, Y. C. Loraine;
- Rimmington, Debra;
- Bosch, Fatima;
- Jimenez, Veronica;
- Yeo, Giles S. H.;
- O’Rahilly, Stephen;
- Ashcroft, Frances M.;
- Coll, Anthony P.;
- Cox, Roger D.
Publication type:
Article
Uncoupling Antisense-Mediated Silencing and DNA Methylation in the Imprinted Gnas Cluster.
Published in:
PLoS Genetics, 2011, v. 7, n. 3, p. 1, doi. 10.1371/journal.pgen.1001347
By:
- Williamson, Christine M.;
- Ball, Simon T.;
- Dawson, Claire;
- Mehta, Stuti;
- Beechey, Colin V.;
- Fray, Martin;
- Teboul, Lydia;
- Dear, T. Neil;
- Kelsey, Gavin;
- Peters, Jo
Publication type:
Article
Characterisation and use of a functional Gadd45g bacterial artificial chromosome.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35458-5
By:
- Warr, Nick;
- May, Joel;
- Teboul, Lydia;
- Suzuki, Toru;
- Asami, Maki;
- Perry, Anthony C. F.;
- Wells, Sara;
- Greenfield, Andy
Publication type:
Article
Improving laboratory animal genetic reporting: LAG-R guidelines.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49439-y
By:
- Teboul, Lydia;
- Amos-Landgraf, James;
- Benavides, Fernando J.;
- Birling, Marie-Christine;
- Brown, Steve D. M.;
- Bryda, Elizabeth;
- Bunton-Stasyshyn, Rosie;
- Chin, Hsian-Jean;
- Crispo, Martina;
- Delerue, Fabien;
- Dobbie, Michael;
- Franklin, Craig L.;
- Fuchtbauer, Ernst-Martin;
- Gao, Xiang;
- Golzio, Christelle;
- Haffner, Rebecca;
- Hérault, Yann;
- Hrabe de Angelis, Martin;
- Lloyd, Kevin C. Kent;
- Magnuson, Terry R.
Publication type:
Article
Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair.
Published in:
Genome Medicine, 2016, v. 8, p. 1, doi. 10.1186/s13073-016-0273-4
By:
- Mianné, Joffrey;
- Chessum, Lauren;
- Kumar, Saumya;
- Aguilar, Carlos;
- Codner, Gemma;
- Hutchison, Marie;
- Parker, Andrew;
- Mallon, Ann-Marie;
- Wells, Sara;
- Simon, Michelle M.;
- Teboul, Lydia;
- Brown, Steve D. M.;
- Bowl, Michael R.
Publication type:
Article
Screening and validation of genome-edited animals.
Published in:
Laboratory Animals, 2022, v. 56, n. 1, p. 69, doi. 10.1177/00236772211016922
By:
- Bunton-Stasyshyn, Rosie K;
- Codner, Gemma F;
- Teboul, Lydia
Publication type:
Article
Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.
Published in:
PLoS Genetics, 2022, v. 18, n. 1, p. 1, doi. 10.1371/journal.pgen.1009937
By:
- Newton, Sherylanne;
- Kong, Fanbo;
- Carlton, Adam J.;
- Aguilar, Carlos;
- Parker, Andrew;
- Codner, Gemma F.;
- Teboul, Lydia;
- Wells, Sara;
- Brown, Steve D. M.;
- Marcotti, Walter;
- Bowl, Michael R.
Publication type:
Article
Identification of cellular retinoic acid binding protein 2 (CRABP2) as downstream target of nuclear factor I/X (NFIX): implications for skeletal dysplasia syndromes.
Published in:
JBMR Plus, 2024, v. 8, n. 7, p. 1, doi. 10.1093/jbmrpl/ziae060
By:
- Kooblall, Kreepa G;
- Stevenson, Mark;
- Heilig, Raphael;
- Stewart, Michelle;
- Wright, Benjamin;
- Lockstone, Helen;
- Buck, David;
- Fischer, Roman;
- Wells, Sara;
- Lines, Kate E;
- Teboul, Lydia;
- Hennekam, Raoul C;
- Thakker, Rajesh V
Publication type:
Article

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