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Alzheimer's Prevention Initiative: A Plan to Accelerate the Evaluation of Presymptomatic Treatments.
- Published in:
- Journal of Alzheimer's Disease, 2011, v. 26, p. 321, doi. 10.3233/JAD-2011-0059
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- Publication type:
- Article
Alzheimer's Prevention Initiative: A Plan to Accelerate the Evaluation of Presymptomatic Treatments.
- Published in:
- Journal of Alzheimer's Disease, 2011, v. 26, p. 321
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- Publication type:
- Article
Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments.
- Published in:
- 2011
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- Publication type:
- journal article
Rationale for the selection of dual primary endpoints in prevention studies of cognitively unimpaired individuals at genetic risk for developing symptoms of Alzheimer's disease.
- Published in:
- Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01183-z
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- Publication type:
- Article
Pharmacological Treatment of Neuropsychiatric Symptoms of Dementia.
- Published in:
- JAMA: Journal of the American Medical Association, 2005, v. 293, n. 18, p. 2211, doi. 10.1001/jama.293.18.2211-b
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- Publication type:
- Article
Memantine for Patients With Alzheimer Disease—Reply.
- Published in:
- 2004
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- Publication type:
- Letter
Memantine Treatment in Patients With Moderate to Severe Alzheimer Disease Already Receiving Donepezil: A Randomized Controlled Trial.
- Published in:
- JAMA: Journal of the American Medical Association, 2004, v. 291, n. 3, p. 317, doi. 10.1001/jama.291.3.317
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- Publication type:
- Article
Treating Behavioral Problems in Patients With Alzheimer's Disease.
- Published in:
- Psychiatric Times, 2007, v. 24, p. 11
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- Publication type:
- Article
Therapy with l-deprenyl (selegiline) and relation to abuse liability<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1994, v. 56, p. 750, doi. 10.1038/clpt.1994.205
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- Publication type:
- Article
BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain.
- Published in:
- 2020
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- Publication type:
- journal article
Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials.
- Published in:
- 2018
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- Publication type:
- journal article
Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial.
- Published in:
- 2015
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- Publication type:
- journal article
APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts.
- Published in:
- 2017
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- Publication type:
- journal article
Impact of Zumba on Cognition and Quality of Life is Independent of APOE4 Carrier Status in Cognitively Unimpaired Older Women: A 6-Month Randomized Controlled Pilot Study.
- Published in:
- American Journal of Alzheimer's Disease & Other Dementias, 2020, v. 35, p. 1, doi. 10.1177/1533317519868370
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- Publication type:
- Article
Detection of Amyloid β Signature in the Lens and Its Correlation in the Brain to Aid in the Diagnosis of Alzheimer’s Disease.
- Published in:
- American Journal of Alzheimer's Disease & Other Dementias, 2015, v. 30, n. 8, p. 738, doi. 10.1177/1533317513520214
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- Publication type:
- Article
Alzheimer's Prevention Initiative Generation Program: Development of an APOE genetic counseling and disclosure process in the context of clinical trials.
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- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, v. 5, n. 1, p. 705, doi. 10.1016/j.trci.2019.09.013
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- Publication type:
- Article
Enrichment factors for clinical trials in mild‐to‐moderate Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, v. 5, n. 1, p. 164, doi. 10.1016/j.trci.2019.04.001
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- Publication type:
- Article
The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, v. 5, n. 1, p. 216, doi. 10.1016/j.trci.2019.02.005
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- Publication type:
- Article
Adherence/Retention Alzheimer's Prevention Initiative Colombia Plan.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2018, v. 4, n. 1, p. 283, doi. 10.1016/j.trci.2018.06.010
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- Publication type:
- Article
The Alzheimer's Prevention Initiative Autosomal‐Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal‐dominant Alzheimer's disease, including a placebo‐treated noncarrier cohort
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2018, v. 4, n. 1, p. 150, doi. 10.1016/j.trci.2018.02.002
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- Publication type:
- Article
Association between clinical dementia rating and clinical outcomes in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2024, v. 16, n. 1, p. 1, doi. 10.1002/dad2.12522
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- Publication type:
- Article
Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease.
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- JAMA Dermatology, 2015, v. 151, n. 8, p. 912, doi. 10.1001/jamaneurol.2015.1099
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- Publication type:
- Article
The Alzheimer's Prevention Registry: Accelerating recruitment and enrollment into Alzheimer's‐focused studies: Epidemiology / Innovative methods in epidemiology (i.e., assessment methods, design, recruitment strategies, statistical methods, etc.).
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043931
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- Publication type:
- Article
The Alzheimer's Prevention Registry: Success metrics and lessons learned in registry member retention through online engagement campaigns: Epidemiology / Innovative methods in epidemiology (i.e., assessment methods, design, recruitment strategies, statistical methods, etc.)
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043531
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- Publication type:
- Article
Success of referring participants to the Generation program and lessons learned for future enrollment into Alzheimer's disease prevention trials: Human: Improving clinical trial methodology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043112
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- Publication type:
- Article
Depression and anxiety disorder along life in familial Alzheimer's disease in the API ADAD Colombia trial: Neuropsychiatry and behavioral neurology/Assessment/Measurement of neuropsychiatric/Behavioral and psychological symptoms.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041314
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- Publication type:
- Article
Sex differences in neurodegeneration and memory performance in preclinical autosomal dominant Alzheimer's disease: Baseline findings from the API ADAD trial: Intersections of sex/gender and race/ethnicity in cognitive aging and Alzheimer's disease trajectories
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041225
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- Publication type:
- Article
The API Generation program: Umibecestat treatment and discontinuation effects on hippocampal and whole brain volumes in the overall population and amyloid‐negative APOE4 homozygotes: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041142
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- Publication type:
- Article
Umibecestat in the API Generation program: Worsening in RBANS and/or CDR on treatment reverses after wash‐out: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041140
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- Publication type:
- Article
The Generation program: Baseline characteristics of cognitively unimpaired APOE4 carriers recruited for Generation study 1 and Generation study 2: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041139
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- Publication type:
- Article
Screening characteristics of PSEN1 E280A mutation carriers and non‐carriers in the API Autosomal Dominant Alzheimer's Disease Colombia Trial: Neuropsychiatry and behavioral neurology/presymptomatic disease/prodromal disease/prodromal states.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040336
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- Publication type:
- Article
The Alzheimer's prevention initiative Generation program: A global perspective on best practices for site support and engagement to accelerate participant recruitment: Clinical trial design and implementation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039186
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- Publication type:
- Article
Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1483, doi. 10.1002/alz.12164
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- Publication type:
- Article
Brain imaging measurements of fibrillar amyloid‐β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 4, p. 598, doi. 10.1016/j.jalz.2019.08.195
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- Publication type:
- Article
F4‐04‐03: RELATIONSHIPS BETWEEN BASELINE BRAIN IMAGING BIOMARKER MEASUREMENTS AND AGE IN THE API AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE COLOMBIA TRIAL.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1223, doi. 10.1016/j.jalz.2019.06.4727
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- Publication type:
- Article
F4‐04‐04: ASSOCIATION BETWEEN CEREBRAL AMYLOIDOSIS AND WORSE COGNITIVE PERFORMANCE IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE: BASELINE FINDINGS FROM THE API COLOMBIA AUTOSOMAL DOMINANT AD TRIAL.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1224, doi. 10.1016/j.jalz.2019.06.4728
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- Publication type:
- Article
F4‐04‐01: TRIAL DESIGN, DATA SHARING RISK MITIGATION, AND BASELINE CLINICAL AND COGNITIVE DATA FROM THE API AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE COLOMBIA TRIAL.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1222, doi. 10.1016/j.jalz.2019.06.4725
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- Publication type:
- Article
P3‐033: GENEMATCH: A NOVEL RECRUITMENT REGISTRY OF APOE CHARACTERIZED ADULTS TO ACCELERATE RECRUITMENT AND ENROLLMENT INTO ALZHEIMER'S PREVENTION STUDIES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P938, doi. 10.1016/j.jalz.2019.06.3059
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- Publication type:
- Article
O3‐10‐02: VERUBECESTAT‐INDUCED BRAIN VOLUME LOSS OCCURS RAPIDLY AND ONLY IN AMYLOID‐ENRICHED BRAIN REGIONS IN EPOCH, A PHASE 3 TRIAL IN MILD‐TO‐MODERATE ALZHEIMER'S DISEASE PATIENTS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P909, doi. 10.1016/j.jalz.2019.06.4679
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- Publication type:
- Article
O3‐02‐02: AMYLOID PET, TAU PET, AND MRI MEASUREMENTS IN COGNITIVELY UNIMPAIRED PERSONS WITH TWO, ONE, AND NO COPIES OF THE APOE4 ALLELE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P878, doi. 10.1016/j.jalz.2019.06.4631
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- Publication type:
- Article
FTS3‐01‐05: FURTHER ANALYSES OF COGNITIVE OUTCOMES IN THE APECS PHASE‐3 TRIAL OF VERUBECESTAT IN PRODROMAL AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P874, doi. 10.1016/j.jalz.2019.06.4622
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- Publication type:
- Article
FTS3‐01‐02: SUBGROUP POPULATIONS IN AMARANTH, A RANDOMIZED PHASE 2/3 STUDY IN EARLY ALZHEIMER'S DISEASE WITH LANABECESTAT.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P872, doi. 10.1016/j.jalz.2019.06.4619
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- Publication type:
- Article
P2‐430: RELATIONSHIPS BETWEEN LONGITUDINAL RATES OF LEARNING AND MEMORY DECLINE AND DIFFERENT FORMS OF CEREBROVASCULAR PATHOLOGY IN COGNITIVELY UNIMPAIRED BRAIN DONORS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P777, doi. 10.1016/j.jalz.2019.06.2837
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- Publication type:
- Article
F2‐03‐04: ASSESSING CLINICAL MEANINGFULNESS OF OUTCOMES IN THE ALZHEIMER'S PREVENTION INITIATIVE GENERATION PROGRAM.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P520, doi. 10.1016/j.jalz.2019.06.4427
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- Publication type:
- Article
P1‐378: SEX‐SPECIFIC ASSOCIATIONS BETWEEN MARKERS OF ALZHEIMER'S DISEASE PATHOLOGY, NEURODEGENERATION AND COGNITION IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P399, doi. 10.1016/j.jalz.2019.06.933
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- Publication type:
- Article
GeneMatch: A novel recruitment registry using at‐home APOE genotyping to enhance referrals to Alzheimer's prevention studies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, n. 4, p. 515, doi. 10.1016/j.jalz.2018.12.007
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- Publication type:
- Article
DT‐01‐04: LANABECESTAT: BASELINE CHARACTERISTICS OF PARTICIPANTS RANDOMIZED IN THE PHASE 2/3 AMARANTH STUDY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1666, doi. 10.1016/j.jalz.2018.07.006
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- Publication type:
- Article
P4‐318: PET MEASUREMENTS OF PHF TAU BURDEN IN COGNITIVELY UNIMPAIRED PERSONS WITH TWO, ONE AND NO COPIES OF THE APOE4 ALLELE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1580, doi. 10.1016/j.jalz.2018.07.141
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- Publication type:
- Article
P4‐299: TAU ACCUMULATION IN THE ENTORHINAL CORTEX AND PRECUNEUS IS ASSOCIATED WITH CORTICAL AMYLOID‐BETA BURDEN, AGE AND WORSE MEMORY PERFORMANCE IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1567, doi. 10.1016/j.jalz.2018.07.121
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- Publication type:
- Article
P4‐209: A PUBLIC RESOURCE OF BASELINE DATA FROM THE API AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE COLOMBIA TRIAL.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1521, doi. 10.1016/j.jalz.2018.07.030
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- Publication type:
- Article