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Metal Chelation as a Potential Therapy for Alzheimer's Disease.
- Published in:
- Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 292, doi. 10.1111/j.1749-6632.2000.tb06938.x
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- Publication type:
- Article
Significant Upregulation of Alzheimer's β‐Amyloid Levels in a Living System Induced by Extracellular Elastin Polypeptides.
- Published in:
- Angewandte Chemie, 2019, v. 131, n. 51, p. 18876, doi. 10.1002/ange.201912399
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- Publication type:
- Article
In Vivo Quasi-Elastic Light Scattering Eye Scanner Detects Molecular Aging in Humans.
- Published in:
- 2020
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- Publication type:
- journal article
Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density.
- Published in:
- 2010
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- Publication type:
- journal article
Amyloid-β Production Via Cleavage of Amyloid-β Protein Precursor is Modulated by Cell Density.
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 22, n. 2, p. 683, doi. 10.3233/JAD-2010-100816
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- Publication type:
- Article
PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses.
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 20, n. 2, p. 509, doi. 10.3233/JAD-2010-1390
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- Publication type:
- Article
Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice.
- Published in:
- Scientific Reports, 2014, p. 1, doi. 10.1038/srep03766
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- Publication type:
- Article
The predictive validity of a Brain Care Score for late-life depression and a composite outcome of dementia, stroke, and late-life depression: data from the UK Biobank cohort.
- Published in:
- Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2024.1373797
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- Publication type:
- Article
Optogenetic Pacing: Current Insights and Future Potential.
- Published in:
- Research Reports in Clinical Cardiology, 2020, v. 11, p. 49, doi. 10.2147/RRCC.S242650
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- Publication type:
- Article
The Telomere Connection.
- Published in:
- Alternative & Complementary Therapies, 2018, v. 24, n. 4, p. 167, doi. 10.1089/act.2018.29174.dch
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- Publication type:
- Article
Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34679-7
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- Publication type:
- Article
Cerebrospinal Fluid Levels of Amyloid Precursor Protein and Amyloid β-Peptide in Alzheimer’s Disease and Major Depression – Inverse Correlation with Dementia Severity.
- Published in:
- European Neurology, 1998, v. 39, n. 2, p. 111, doi. 10.1159/000007917
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- Publication type:
- Article
Cytokine-mediated inflammation mediates painful neuropathy from metabolic syndrome.
- Published in:
- PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0192333
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- Publication type:
- Article
Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-β Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 39, p. 13110, doi. 10.1523/JNEUROSCI.3872-10.2010
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- Publication type:
- Article
Isoflurane-Induced Caspase-3 Activation Is Dependent on Cytosolic Calcium and Can Be Attenuated by Memantine.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 17, p. 4551, doi. 10.1523/JNEUROSCI.5694-07.2008
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- Publication type:
- Article
γ-Secretase modulators reduce endogenous amyloid β<sub>42</sub> levels in human neural progenitor cells without altering neuronal differentiation.
- Published in:
- FASEB Journal, 2015, v. 29, n. 8, p. 3335, doi. 10.1096/fj.15-271015
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- Publication type:
- Article
FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness.
- Published in:
- FASEB Journal, 2015, v. 29, n. 6, p. 2628, doi. 10.1096/fj.14-261453
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- Publication type:
- Article
Hypoxic ischemia and proteasome dysfunction alter tau isoform ratio by inhibiting exon 10 splicing.
- Published in:
- Journal of Neurochemistry, 2010, v. 114, n. 1, p. 160, doi. 10.1111/j.1471-4159.2010.06732.x
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- Publication type:
- Article
APP substitutions V715F and L720P alter PS1 conformation and differentially affect Aβ and AICD generation.
- Published in:
- Journal of Neurochemistry, 2005, v. 95, n. 2, p. 446, doi. 10.1111/j.1471-4159.2005.03381.x
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- Publication type:
- Article
Redox-Active Metals, Oxidative Stress, and Alzheimer's Disease Pathology.
- Published in:
- Annals of the New York Academy of Sciences, 2004, v. 1012, n. 1, p. 153, doi. 10.1196/annals.1306.012
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- Publication type:
- Article
On the Meta-Analysis of Genome-Wide Association Studies: A Robust and Efficient Approach to Combine Population and Family-Based Studies.
- Published in:
- Human Heredity, 2012, v. 73, n. 1, p. 35, doi. 10.1159/000331219
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- Publication type:
- Article
The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38645-0
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- Publication type:
- Article
Silencing of the Drosophila ortholog of SOX5 in heart leads to cardiac dysfunction as detected by optical coherence tomography.
- Published in:
- Human Molecular Genetics, 2013, v. 22, n. 18, p. 3798
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- Publication type:
- Article
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate α-secretase activity.
- Published in:
- Human Molecular Genetics, 2009, v. 18, n. 20, p. 3987, doi. 10.1093/hmg/ddp323
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- Publication type:
- Article
Genome-wide association studies in Alzheimer's disease.
- Published in:
- Human Molecular Genetics, 2009, v. 18, n. R2, p. R137, doi. 10.1093/hmg/ddp406
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- Publication type:
- Article
Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease.
- Published in:
- Human Molecular Genetics, 2007, v. 16, n. 22, p. 2703, doi. 10.1093/hmg/ddm224
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- Publication type:
- Article
Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes.
- Published in:
- Human Molecular Genetics, 2007, v. 16, n. 21, p. 2626
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- Publication type:
- Article
Alzheimer's disease: one disorder, too many genes?
- Published in:
- Human Molecular Genetics, 2004, v. 13, n. suppl_1, p. R135
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- Publication type:
- Article
Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer's disease trigger BACE1 accumulation in axonal swellings.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 570, p. 1, doi. 10.1126/scitranslmed.aba1871
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- Publication type:
- Article
Aβ-accelerated neurodegeneration caused by Alzheimer's-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 563, p. 1, doi. 10.1126/scitranslmed.aaz2541
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- Publication type:
- Article
Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease.
- Published in:
- Science Translational Medicine, 2016, v. 8, n. 340, p. 1, doi. 10.1126/scitranslmed.aaf1059
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- Publication type:
- Article
Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.
- Published in:
- Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-023-00700-w
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- Publication type:
- Article
Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease.
- Published in:
- Brain: A Journal of Neurology, 2024, v. 147, n. 6, p. 2158, doi. 10.1093/brain/awae034
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- Publication type:
- Article
γ‐Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer‐Related Pathologies in a Mouse Model of Down Syndrome.
- Published in:
- Annals of Neurology, 2024, v. 96, n. 2, p. 390, doi. 10.1002/ana.26958
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- Publication type:
- Article
Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ‐Secretase Modulator.
- Published in:
- Annals of Neurology, 2023, v. 94, n. 2, p. 245, doi. 10.1002/ana.26659
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- Publication type:
- Article
Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer’s Aβ peptides.
- Published in:
- Journal of Biological Inorganic Chemistry (JBIC), 2004, v. 9, n. 8, p. 954, doi. 10.1007/s00775-004-0602-8
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- Publication type:
- Article
Alzheimer's disease: The latest suspect.
- Published in:
- Nature, 2008, v. 454, n. 7205, p. 706, doi. 10.1038/454706a
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- Publication type:
- Article
Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses.
- Published in:
- Nature Reviews Neuroscience, 2008, v. 9, n. 10, p. 768, doi. 10.1038/nrn2494
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- Publication type:
- Article
Evaluation of bumetanide as a potential therapeutic agent for Alzheimer's disease.
- Published in:
- Frontiers in Pharmacology, 2023, v. 14, p. 01, doi. 10.3389/fphar.2023.1190402
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- Publication type:
- Article
A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data.
- Published in:
- Genes, 2022, v. 13, n. 1, p. 112, doi. 10.3390/genes13010112
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- Publication type:
- Article
The neuroimmune axis of Alzheimer's disease.
- Published in:
- Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01155-w
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- Publication type:
- Article
Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy–Weinberg equilibrium.
- Published in:
- European Journal of Human Genetics, 2009, v. 17, n. 12, p. 1676, doi. 10.1038/ejhg.2009.85
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- Publication type:
- Article
Correction: Palmitoylated APP Forms Dimers, Cleaved by BACE1.
- Published in:
- PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0299972
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- Publication type:
- Article
3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish".
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0139-7
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- Publication type:
- Article
Synaptotagmins interact with APP and promote Aβ generation.
- Published in:
- Molecular Neurodegeneration, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13024-015-0028-5
- By:
- Publication type:
- Article
Regulation of key proteins in Alzheimer's disease molecular pathogenesis by ubiquilin-1.
- Published in:
- 2013
- By:
- Publication type:
- Abstract
Decoding Alzheimer's in the age of genome-wide analyses.
- Published in:
- 2013
- By:
- Publication type:
- Abstract
An AICD-based functional screen to identify APP metabolism regulators.
- Published in:
- Molecular Neurodegeneration, 2007, v. 2, p. 15, doi. 10.1186/1750-1326-2-15
- By:
- Publication type:
- Article
Hypocapnia Induces Caspase-3 Activation and Increases Aβ Production.
- Published in:
- Neurodegenerative Diseases, 2004, v. 1, n. 1, p. 29, doi. 10.1159/000076667
- By:
- Publication type:
- Article
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.
- Published in:
- Nature Genetics, 2008, v. 40, n. 7, p. 827, doi. 10.1038/ng.171
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- Publication type:
- Article