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Pharmacokinetic/pharmacodynamic modeling and simulation of dotinurad, a novel uricosuric agent, in healthy volunteers.
- Published in:
- Pharmacology Research & Perspectives, 2019, v. 7, n. 6, p. 1, doi. 10.1002/prp2.533
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- Publication type:
- Article
Cancer cell-targeted drug delivery utilizing oligopeptide transport activity.
- Published in:
- International Journal of Cancer, 2000, v. 88, n. 2, p. 274, doi. 10.1002/1097-0215(20001015)88:2<274::AID-IJC20>3.0.CO;2-5
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- Publication type:
- Article
ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding pocket.
- Published in:
- FASEB Journal, 2020, v. 34, n. 4, p. 4890, doi. 10.1096/fj.201902338RR
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- Publication type:
- Article
Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38667-8
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- Publication type:
- Article
Putative Transport Mechanism and Intracellular Fate of Trans-1-Amino-3-<sup>18</sup>F-Fluorocyclobutanecarboxylic Acid in Human Prostate Cancer.
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- Journal of Nuclear Medicine, 2011, v. 52, n. 5, p. 822, doi. 10.2967/jnumed.110.086074
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- Publication type:
- Article
Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala<sup>2</sup>, D-Leu<sup>5</sup>]-enkephalin.
- Published in:
- Journal of Pharmacy & Pharmacology, 2003, v. 55, n. 7, p. 1013
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- Publication type:
- Article
Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein.
- Published in:
- Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 5, p. 699, doi. 10.1211/0022357011775820
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- Publication type:
- Article
Molecular and functional identification of large neutral amino acid transporters LAT1 and LAT2 and their pharmacological relevance at the blood-brain barrier.
- Published in:
- Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 4, p. 497, doi. 10.1211/0022357011775794
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- Publication type:
- Article
Effect of γ-butyrobetaine on fatty liver in juvenile visceral steatosis mice.
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- Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 4, p. 527, doi. 10.1211/0022357011775631
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- Publication type:
- Article
Secretory transport of p-aminohippuric acid across intestinal epithelial cells in Caco-2 cells and isolated intestinal tissue.
- Published in:
- Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 1, p. 73, doi. 10.1211/0022357011775217
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- Publication type:
- Article
Immunohistochemical and Functional Characterization of pH-dependent Intestinal Absorption of Weak Organic Acids by the Monocarboxylic Acid Transporter MCT1.
- Published in:
- Journal of Pharmacy & Pharmacology, 1999, v. 51, n. 10, p. 1113, doi. 10.1211/0022357991776804
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- Publication type:
- Article
Characteristics of L-Carnitine Transport in Cultured Human Hepatoma HLF Cells.
- Published in:
- Journal of Pharmacy & Pharmacology, 1999, v. 51, n. 8, p. 935, doi. 10.1211/0022357991773195
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- Publication type:
- Article
Roles and Application of Extracellular Vesicles Occurring Endogenously and Naturally.
- Published in:
- Pharmaceutical Research, 2023, v. 40, n. 4, p. 793, doi. 10.1007/s11095-023-03519-8
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- Publication type:
- Article
Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 7, p. 1549, doi. 10.1007/s11095-022-03223-z
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- Publication type:
- Article
Model Analysis of the Apparent Saturation Kinetics of Purine Nucleobase Uptake in Cells co-Expressing Transporter and Metabolic Enzyme.
- Published in:
- Pharmaceutical Research, 2021, v. 38, n. 9, p. 1585, doi. 10.1007/s11095-021-03086-w
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- Publication type:
- Article
Uptake Pathway of Apple-derived Nanoparticle by Intestinal Cells to Deliver its Cargo.
- Published in:
- Pharmaceutical Research, 2021, v. 38, n. 3, p. 523, doi. 10.1007/s11095-021-03018-8
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- Publication type:
- Article
Different Efflux Transporter Affinity and Metabolism of <sup>99m</sup>Tc-2-Methoxyisobutylisonitrile and <sup>99m</sup>Tc-Tetrofosmin for Multidrug Resistance Monitoring in Cancer.
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 1, p. N.PAG, doi. 10.1007/s11095-018-2548-5
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- Publication type:
- Article
Sodium and Chloride Ion-Dependent Transport of β-Alanine Across the Blood-Brain Barrier.
- Published in:
- Journal of Neurochemistry, 1996, v. 67, n. 1, p. 330, doi. 10.1046/j.1471-4159.1996.67010330.x
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- Publication type:
- Article
Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers.
- Published in:
- European Journal of Clinical Pharmacology, 2014, v. 70, n. 9, p. 1087, doi. 10.1007/s00228-014-1705-y
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- Publication type:
- Article
Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate.
- Published in:
- Nephrology Dialysis Transplantation, 2013, v. 28, n. 3, p. 603, doi. 10.1093/ndt/gfs574
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- Publication type:
- Article
Substrate- and Dose-Dependent Drug Interactions with Grapefruit Juice Caused by Multiple Binding Sites on OATP2B1.
- Published in:
- Pharmaceutical Research, 2014, v. 31, n. 8, p. 2035, doi. 10.1007/s11095-014-1305-7
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- Publication type:
- Article
Intestinal Absorption of HMG-CoA Reductase Inhibitor Pravastatin Mediated by Organic Anion Transporting Polypeptide.
- Published in:
- Pharmaceutical Research, 2010, v. 27, n. 10, p. 2141, doi. 10.1007/s11095-010-0216-5
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- Publication type:
- Article
Involvement of Organic Anion Transporting Polypeptide 1a5 (Oatp1a5) in the Intestinal Absorption of Endothelin Receptor Antagonist in Rats.
- Published in:
- Pharmaceutical Research, 2008, v. 25, n. 5, p. 1085, doi. 10.1007/s11095-007-9472-4
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- Publication type:
- Article
Predominant Contribution of Rat Organic Anion Transporting Polypeptide-2 (Oatp2) to Hepatic Uptake of β-Lactam Antibiotics.
- Published in:
- Pharmaceutical Research, 2008, v. 25, n. 3, p. 578, doi. 10.1007/s11095-007-9427-9
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- Publication type:
- Article
Involvement of Uric Acid Transporters in Alteration of Serum Uric Acid Level by Angiotensin II Receptor Blockers.
- Published in:
- Pharmaceutical Research, 2008, v. 25, n. 3, p. 639, doi. 10.1007/s11095-007-9401-6
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- Publication type:
- Article
Decreased Biosynthesis of Lung Surfactant Constituent Phosphatidylcholine Due to Inhibition of Choline Transporter by Gefitinib in Lung Alveolar Cells.
- Published in:
- Pharmaceutical Research, 2008, v. 25, n. 2, p. 417, doi. 10.1007/s11095-007-9362-9
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- Publication type:
- Article
Decreased Proliferation and Erythroid Differentiation of K562 Cells by siRNA-induced Depression of OCTN1 (SLC22A4) Transporter Gene.
- Published in:
- Pharmaceutical Research, 2007, v. 24, n. 9, p. 1628, doi. 10.1007/s11095-007-9290-8
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- Publication type:
- Article
Prostaglandin Transporter OATV2 AM SLC02A1 Is Essential for Body Temperature Regulation during Fever.
- Published in:
- Journal of Neuroscience, 2018, v. 38, n. 24, p. 5584, doi. 10.1523/JNEUROSCI.3276-17.2018
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- Publication type:
- Article
Quantitative analysis of the impact of membrane permeability on intestinal first‐pass metabolism of CYP3A substrates.
- Published in:
- Biopharmaceutics & Drug Disposition, 2024, v. 45, n. 1, p. 3, doi. 10.1002/bdd.2379
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- Publication type:
- Article
Effect of endogenous multidrug resistance 1 and P‐glycoprotein expression on anticancer drug resistance in colon cancer cell lines.
- Published in:
- Biopharmaceutics & Drug Disposition, 2019, v. 40, n. 1, p. 32, doi. 10.1002/bdd.2167
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- Publication type:
- Article
Contribution of equilibrative nucleoside transporters 1 and 2 to gemcitabine uptake in pancreatic cancer cells.
- Published in:
- Biopharmaceutics & Drug Disposition, 2018, v. 39, n. 5, p. 256, doi. 10.1002/bdd.2131
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- Publication type:
- Article
Contribution of equilibrative nucleoside transporter(s) to intestinal basolateral and apical transports of anticancer trifluridine.
- Published in:
- Biopharmaceutics & Drug Disposition, 2018, v. 39, n. 1, p. 38, doi. 10.1002/bdd.2110
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- Publication type:
- Article
Revisiting the role of gut wall in the fate of orally administered drugs: Why now and to what effect?
- Published in:
- 2017
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- Publication type:
- Editorial
Putative roles of organic anion transporting polypeptides (OATPs) in cell survival and progression of human cancers.
- Published in:
- Biopharmaceutics & Drug Disposition, 2014, v. 35, n. 8, p. 463, doi. 10.1002/bdd.1915
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- Publication type:
- Article
SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria.
- Published in:
- Biopharmaceutics & Drug Disposition, 2014, v. 35, n. 7, p. 391, doi. 10.1002/bdd.1909
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- Publication type:
- Article
Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22a21).
- Published in:
- Biopharmaceutics & Drug Disposition, 2013, v. 34, n. 1, p. 29, doi. 10.1002/bdd.1816
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- Publication type:
- Article
Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5.
- Published in:
- Biopharmaceutics & Drug Disposition, 2012, v. 33, n. 6, p. 332, doi. 10.1002/bdd.1809
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- Publication type:
- Article
Physiologically based pharmacokinetic (PBPK) modeling: It is here to stay!
- Published in:
- Biopharmaceutics & Drug Disposition, 2012, v. 33, n. 2, p. 47, doi. 10.1002/bdd.1776
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- Publication type:
- Article
In-vitro evidence of enhanced breast cancer resistance protein-mediated intestinal urate secretion by uremic toxins in Caco-2 cells.
- Published in:
- Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 2, p. 170, doi. 10.1111/jphp.12328
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- Publication type:
- Article
Imaging of hepatic drug transporters with [<sup>131</sup>I]6-β-iodomethyl-19-norcholesterol.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50049-8
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- Publication type:
- Article
Identification of the Catechin Uptake Transporter Responsible for Intestinal Absorption of Epigallocatechin Gallate in Mice.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47214-4
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- Publication type:
- Article
Extra-Renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0030456
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- Publication type:
- Article
Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter.
- Published in:
- Nature Genetics, 1999, v. 21, n. 1, p. 91, doi. 10.1038/5030
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- Publication type:
- Article
Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples.
- Published in:
- Communications Chemistry, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42004-020-00430-w
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- Publication type:
- Article
Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells.
- Published in:
- Journal of Biomedical Science, 2006, v. 13, n. 4, p. 525, doi. 10.1007/s11373-006-9071-0
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- Publication type:
- Article
Cyclophosphamide‐induced hemorrhagic cystitis in young patients with solid tumors: A single institution study.
- Published in:
- Asia Pacific Journal of Clinical Oncology, 2018, v. 14, n. 5, p. e460, doi. 10.1111/ajco.13048
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- Publication type:
- Article
Quantitative Analysis of Gastrointestinal Water Dynamics by Means of a Physiologically Based Fluid Kinetic Model.
- Published in:
- AAPS Journal, 2023, v. 25, n. 3, p. 1, doi. 10.1208/s12248-023-00809-2
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- Publication type:
- Article
Roles of Organic Anion Transporting Polypeptide 2A1 (OATP2A1/SLCO2A1) in Regulating the Pathophysiological Actions of Prostaglandins.
- Published in:
- AAPS Journal, 2018, v. 20, n. 1, p. 1, doi. 10.1208/s12248-017-0163-8
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- Publication type:
- Article
How Does Whisky Lower Serum Urate Level?
- Published in:
- Phytotherapy Research, 2014, v. 28, n. 5, p. 788, doi. 10.1002/ptr.5063
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- Publication type:
- Article
Intraocular Penetration Kinetics of Prednisolone after Subconjunctival Injection in Rabbits.
- Published in:
- Ophthalmic Research, 1988, v. 20, n. 1, p. 31, doi. 10.1159/000266253
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- Publication type:
- Article