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A glucagon analogue decreases body weight in mice via signalling in the liver.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-01912-0
By:
- Hinds, Charlotte E.;
- Owen, Bryn M.;
- Hope, David C. D.;
- Pickford, Philip;
- Jones, Ben;
- Tan, Tricia M.;
- Minnion, James S.;
- Bloom, Stephen R.
Publication type:
Article
The Metabolomic Effects of Tripeptide Gut Hormone Infusion Compared to Roux-en-Y Gastric Bypass and Caloric Restriction.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 2, p. e767, doi. 10.1210/clinem/dgab608
By:
- Jones, Ben;
- Sands, Caroline;
- Alexiadou, Kleopatra;
- Minnion, James;
- Tharakan, George;
- Behary, Preeshila;
- Ahmed, Ahmed R.;
- Purkayastha, Sanjay;
- Lewis, Matthew R.;
- Bloom, Stephen;
- Li, Jia V.;
- Tan, Tricia M.
Publication type:
Article
Beyond Weight Loss: Establishing a Postbariatric Surgery Patient Support Group—What Do Patients Want?
Published in:
Journal of Obesity, 2018, p. 1, doi. 10.1155/2018/8419120
By:
- Hameed, Saira;
- Salem, Victoria;
- Tan, Tricia M.;
- Collins, Alma;
- Shah, Krishna;
- Scholtz, Samantha;
- Ahmed, Ahmed R.;
- Chahal, Harvinder
Publication type:
Article
A legacy of tinnitus: multiple head and neck paragangliomas.
Published in:
2009
By:
- Tan, Tricia M. M.;
- Hatfield, Emma C. I.;
- Thakker, Rajesh V.;
- Maher, Eamonn R.;
- Meeran, Karim;
- Martin, Niamh M.;
- Turner, Jeremy J.
Publication type:
Case Study
Combination of peptide YY3-36 with GLP-1(7-36) amide causes an increase in first-phase insulin secretion after IV glucose.
Published in:
2014
By:
- Tan, Tricia M;
- Salem, Victoria;
- Troke, Rachel C;
- Alsafi, Ali;
- Field, Benjamin C T;
- De Silva, Akila;
- Misra, Shivani;
- Baynes, Kevin C R;
- Donaldson, Mandy;
- Minnion, James;
- Ghatei, Mohammad A;
- Godsland, Ian F;
- Bloom, Stephen R
Publication type:
journal article
100 years of glucagon and 100 more.
Published in:
Diabetologia, 2023, v. 66, n. 8, p. 1378, doi. 10.1007/s00125-023-05947-y
By:
- Wewer Albrechtsen, Nicolai J.;
- Holst, Jens J.;
- Cherrington, Alan D.;
- Finan, Brian;
- Gluud, Lise Lotte;
- Dean, E. Danielle;
- Campbell, Jonathan E.;
- Bloom, Stephen R.;
- Tan, Tricia M.-M.;
- Knop, Filip K.;
- Müller, Timo D.
Publication type:
Article
Adaptive infusion of a glucagon‐like peptide‐1/glucagon receptor co‐agonist G3215, in adults with overweight or obesity: Results from a phase 1 randomized clinical trial.
Published in:
Diabetes, Obesity & Metabolism, 2024, v. 26, n. 4, p. 1479, doi. 10.1111/dom.15448
By:
- Hope, David C. D.;
- Ansari, Saleem;
- Choudhury, Sirazum;
- Alexiadou, Kleopatra;
- Tabbakh, Yasmin;
- Ilesanmi, Ibiyemi;
- Lazarus, Katharine;
- Davies, Iona;
- Jimenez‐Pacheco, Lara;
- Yang, Wei;
- Ball, Laura‐Jayne;
- Malviya, Reshma;
- Reglinska, Beata;
- Khoo, Bernard;
- Minnion, James;
- Bloom, Stephen R.;
- Tan, Tricia M.‐M.
Publication type:
Article
The effects of kisspeptin on food intake in women with overweight or obesity.
Published in:
Diabetes, Obesity & Metabolism, 2023, v. 25, n. 8, p. 2393, doi. 10.1111/dom.15086
By:
- Izzi‐Engbeaya, Chioma;
- Choudhury, Muhammad M.;
- Patel, Bijal;
- Muzi, Beatrice;
- Qayuum, Ambreen;
- Mills, Edouard G.;
- Ahsan, Maheen;
- Phylactou, Maria;
- Clarke, Sophie A.;
- Aslett, Laura;
- Comninos, Alexander N.;
- Abbara, Ali;
- Tan, Tricia M.;
- Dhillo, Waljit S.
Publication type:
Article
Tripeptide gut hormone infusion does not alter food preferences or sweet taste function in volunteers with obesity and prediabetes/diabetes but promotes restraint eating: A secondary analysis of a randomized single‐blind placebo‐controlled study
Published in:
Diabetes, Obesity & Metabolism, 2023, v. 25, n. 6, p. 1731, doi. 10.1111/dom.15028
By:
- Behary, Preeshila;
- Alessimii, Haya;
- Miras, Alexander D.;
- Tharakan, George;
- Alexiadou, Kleopatra;
- Aldhwayan, Madhawi M.;
- Purkayastha, Sanjay;
- Moorthy, Krishna;
- Ahmed, Ahmed R.;
- Bloom, Stephen R.;
- Tan, Tricia M.
Publication type:
Article
The benefit of dexamethasone in patients with COVID‐19 infection is preserved in patients with diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2022, v. 24, n. 7, p. 1385, doi. 10.1111/dom.14692
By:
- Eng, Pei Chia;
- Distaso, Walter;
- Durreshahwar, Hashmi;
- Shaikhali, Yusuf;
- Narendranathan, Divani;
- Cassin‐Scott, Rebecca;
- Misra, Shivani;
- Hill, Neil E.;
- Tharakan, George;
- Oliver, Nick S.;
- Tan, Tricia M.;
- Izzi‐Engbeaya, Chioma;
- Salem, Victoria
Publication type:
Article
Safety and efficacy of an extended‐release peptide YY analogue for obesity: A randomized, placebo‐controlled, phase 1 trial.
Published in:
Diabetes, Obesity & Metabolism, 2021, v. 23, n. 7, p. 1471, doi. 10.1111/dom.14358
By:
- Tan, Tricia M.‐M.;
- Minnion, James;
- Khoo, Bernard;
- Ball, Laura‐Jayne;
- Malviya, Reshma;
- Day, Emily;
- Fiorentino, Francesca;
- Brindley, Charlie;
- Bush, Jim;
- Bloom, Stephen R.
Publication type:
Article
The future role of gut hormones in the treatment of obesity.
Published in:
Therapeutic Advances in Chronic Disease, 2014, v. 5, n. 1, p. 4, doi. 10.1177/2040622313506730
By:
- Troke, Rachel C.;
- Tan, Tricia M.;
- Bloom, Steve R.
Publication type:
Article
Somatostatin Infusion Lowers Plasma Ghrelin without Reducing Appetite in Adults with Prader-Willi Syndrome.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 8, p. 4162, doi. 10.1210/jc.2004-0835
By:
- Tan, Tricia M.-M.;
- Vanderpump, Mark;
- Khoo, Bernard;
- Patterson, Mike;
- Ghatei, Mohammad A.;
- Goldstone, Anthony P.
Publication type:
Article
Pharmacokinetics, adverse effects and tolerability of a novel analogue of human pancreatic polypeptide, PP 1420.
Published in:
British Journal of Clinical Pharmacology, 2012, v. 73, n. 2, p. 232, doi. 10.1111/j.1365-2125.2011.04082.x
By:
- Tan, Tricia M.;
- Field, Benjamin C. T.;
- Minnion, James S.;
- Cuenco-Shillito, Joyceline;
- Chambers, Edward S.;
- Zac-Varghese, Sagen;
- Brindley, Charlie J.;
- Mt-Isa, Shahrul;
- Fiorentino, Francesca;
- Ashby, Deborah;
- Ward, Ian;
- Ghatei, Mohammad A.;
- Bloom, Stephen R.
Publication type:
Article
Sleeve gastrectomy causes weight‐loss independent improvements in hepatic steatosis.
Published in:
Liver International, 2023, v. 43, n. 9, p. 1890, doi. 10.1111/liv.15614
By:
- McGlone, Emma Rose;
- Siebert, Matthieu;
- Dore, Marian;
- Hope, David C. D.;
- Davies, Iona;
- Owen, Bryn;
- Khoo, Bernard;
- Goldin, Rob;
- Carling, Dave;
- Bloom, Stephen;
- Le Gall, Maude;
- Tan, Tricia M‐M.
Publication type:
Article
Clinical roles in clinical biochemistry: a national survey of practice in the UK.
Published in:
2017
By:
- Choudhury, Sirazum M.;
- Williams, Emma L.;
- Barnes, Sophie C.;
- Alaghband-Zadeh, Jamshid;
- Tan, Tricia M.;
- Cegla, Jaimini
Publication type:
journal article
The preanalytical stability of glucagon as measured by liquid chromatography tandem mass spectrometry and two commercially available immunoassays.
Published in:
2017
By:
- Cegla, Jaimini;
- Jones, Ben J.;
- Howard, James;
- Kay, Richard;
- Creaser, Colin S.;
- Bloom, Stephen R.;
- Tan, Tricia M.
Publication type:
journal article
Redefining ITT cortisol thresholds on Abbott platforms to prevent misdiagnosis of adrenal insufficiency.
Published in:
Clinical Endocrinology, 2024, v. 101, n. 3, p. 195, doi. 10.1111/cen.15074
By:
- Lazarus, Katharine;
- Hayes, Annabel;
- Narula, Kavita;
- Papadopolou, Debbie;
- Tan, Tricia M.‐M.;
- Meeran, Karim;
- Choudhury, Sirazum
Publication type:
Article
The postprandial secretion of peptide YY<sub>1‐36</sub> and <sub>3‐36</sub> in obesity is differentially increased after gastric bypass versus sleeve gastrectomy.
Published in:
Clinical Endocrinology, 2023, v. 99, n. 3, p. 272, doi. 10.1111/cen.14846
By:
- Kowalka, Anna M.;
- Alexiadou, Kleopatra;
- Cuenco, Joyceline;
- Clarke, Rosemary E.;
- Minnion, James;
- Williams, Emma L.;
- Bech, Paul;
- Purkayastha, Sanjay;
- Ahmed, Ahmed R.;
- Takats, Zoltan;
- Whitwell, Harry J.;
- Romero, Maria Gomez;
- Bloom, Stephen R.;
- Camuzeaux, Stephane;
- Lewis, Matthew R.;
- Khoo, Bernard;
- Tan, Tricia M.‐M.
Publication type:
Article
Commentary on "The road to reliable peptide assays is paved with good guidelines".
Published in:
Clinical Endocrinology, 2023, v. 98, n. 6, p. 763, doi. 10.1111/cen.14894
By:
- Kowalka, Anna M.;
- Alexiadou, Kleopatra;
- Cuenco, Joyceline;
- Clarke, Rosemary E.;
- Camuzeaux, Stephane;
- Minnion, James;
- Williams, Emma L.;
- Bech, Paul;
- Purkayastha, Sanjay;
- Ahmed, Ahmed R.;
- Takats, Zoltan;
- Khoo, Bernard;
- Whitwell, Harry J.;
- Romero, Maria G.;
- Bloom, Stephen R.;
- Lewis, Matthew R.;
- Tan, Tricia M.‐M.
Publication type:
Article
Adrenal Vein Sampling: Does the Location of the Non-adrenal Venous Sample Matter?
Published in:
CardioVascular & Interventional Radiology, 2024, v. 47, n. 2, p. 194, doi. 10.1007/s00270-023-03647-z
By:
- Wernig, Florian;
- Dunin-Borkowska, Aleksandra;
- Frisiras, Angelos;
- Khoo, Bernard;
- Todd, Jeannie;
- Di Marco, Aimee;
- Palazzo, F. Fausto;
- Barnes, Sophie C.;
- Tan, Tricia M.;
- Meeran, Karim;
- Alsafi, Ali
Publication type:
Article
Determining the role of novel metabolic pathways in driving intracranial pressure reduction after weight loss.
Published in:
Brain Communications, 2023, v. 5, n. 5, p. 1, doi. 10.1093/braincomms/fcad272
By:
- Alimajstorovic, Zerin;
- Mitchell, James L.;
- Yiangou, Andreas;
- Hancox, Thomas;
- Southam, Andrew D.;
- Grech, Olivia;
- Ottridge, Ryan;
- Winder, Catherine L.;
- Tahrani, Abd A.;
- Tan, Tricia M.;
- Mollan, Susan P.;
- Dunn, Warwick B.;
- Sinclair, Alexandra J.
Publication type:
Article
No Guts, No Loss: Toward the Ideal Treatment for Obesity in the Twenty-First Century.
Published in:
Frontiers in Endocrinology, 2018, p. N.PAG, doi. 10.3389/fendo.2018.00442
By:
- Hope, David C. D.;
- Tan, Tricia M. M.;
- Bloom, Stephen R.
Publication type:
Article
Weight Loss by Low-Calorie Diet Versus Gastric Bypass Surgery in People With Diabetes Results in Divergent Brain Activation Patterns: A Functional MRI Study.
Published in:
2021
By:
- Salem, Victoria;
- Demetriou, Lysia;
- Behary, Preeshila;
- Alexiadou, Kleopatra;
- Scholtz, Samantha;
- Tharakan, George;
- Miras, Alexander D.;
- Purkayastha, Sanjay;
- Ahmed, Ahmed R.;
- Bloom, Stephen R.;
- Wall, Matthew B.;
- Dhillo, Waljit S.;
- Tan, Tricia M.-M.
Publication type:
journal article
Roux-en-Y Gastric Bypass Increases Glycemic Variability and Time in Hypoglycemia in Patients With Obesity and Prediabetes or Type 2 Diabetes: A Prospective Cohort Study.
Published in:
2021
By:
- Ilesanmi, Ibiyemi;
- Tharakan, George;
- Alexiadou, Kleopatra;
- Behary, Preeshila;
- Alessimii, Haya;
- Bovill-Taylor, Candace;
- Kenkre, Julia;
- Choudhury, Sirazum;
- Doyle, Chedie;
- Purkayastha, Sanjay;
- Miras, Alex;
- Tsironis, Christos;
- Chahal, Harvinder;
- Bloom, Stephen R.;
- Oliver, Nick S.;
- Ahmed, Ahmed R.;
- Khoo, Bernard;
- Tan, Tricia M.-M.
Publication type:
journal article
MELAS syndrome, diabetes and thyroid disease: the role of mitochondrial oxidative stress.
Published in:
2009
By:
- Tan, Tricia M. M.;
- Caputo, Carmela;
- Medici, Francesco;
- Pambakian, Alidz L.;
- Dornhorst, Anne;
- Meeran, Karim;
- Williams, Graham R.;
- Khoo, Bernard
Publication type:
Letter
Gastrointestinal Peptides as Therapeutic Targets to Mitigate Obesity and Metabolic Syndrome.
Published in:
2020
By:
- Alexiadou, Kleopatra;
- Tan, Tricia M-M.
Publication type:
journal article
1798-P: Chronic Administration of a Long-Acting Glucagon Analogue Results in Enhanced Insulin Secretory Activity in a Directly-Observed Murine Model.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1798-P
By:
- SUBA, KINGA;
- PATEL, YATEEN S.;
- ALONSO, ALDARA MARTIN;
- SCOTT, REBECCA;
- MINNION, JAMES S.;
- LECLERC, ISABELLE;
- OWEN, BRYN;
- DISTASO, WALTER;
- TAN, TRICIA M.;
- MURPHY, KEVIN;
- BLOOM, STEPHEN;
- RUTTER, GUY A.;
- SALEM, VICTORIA
Publication type:
Article
390-P: Changes in Glycaemic Variability after RYGB: A One-Year Prospective Study with Comparison to Patients with Post-bariatric Hypoglycaemia.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-390-P
By:
- THARAKAN, GEORGE;
- ILESANMI, IBIYEMI I.;
- BEHARY, PREESHILA;
- ALEXIADOU, KLEOPATRA;
- DOYLE JR., CHEDIE S.;
- CHAHAL, HARVINDER;
- PURKAYASTHA, SANJAY;
- MIRAS, ALEXANDER;
- OLIVER, NICK;
- AHMED, AHMED;
- BLOOM, STEPHEN;
- TAN, TRICIA M.
Publication type:
Article
2308-PUB: Liraglutide 3 mg for Weight Loss in a Real-World Setting: Clinical Outcomes after 56 Weeks.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2308-PUB
By:
- BUCKLEY, ADAM J.;
- SULIMAN, MOHAMED;
- TIKRITI, ALIA AL;
- LESSAN, NADER;
- ROUX, CAREL LE;
- TAN, TRICIA M.;
- BARAKAT, MAHA T.
Publication type:
Article
Coinfusion of Low-Dose GLP-1 and Glucagon in Man Results in a Reduction in Food Intake.
Published in:
Diabetes, 2014, v. 63, n. 11, p. 3711, doi. 10.2337/db14-0242
By:
- Cegla, Jaimini;
- Troke, Rachel C.;
- Jones, Ben;
- Tharakan, George;
- Kenkre, Julia;
- McCullough, Katherine A.;
- Thong Lim, Chung;
- Parvizi, Nassim;
- Hussein, Mohamed;
- Chambers, Edward S.;
- Minnion, James;
- Cuenco, Joyceline;
- Ghatei, Mohammad A.;
- Meeran, Karim;
- Tan, Tricia M.;
- Bloom, Stephen R.
Publication type:
Article
Coadministration of Glucagon-Like Peptide-1 During Glucagon Infusion in Humans Results in Increased Energy Expenditure and Amelioration of Hyperglycemia.
Published in:
Diabetes, 2013, v. 62, n. 4, p. 1131, doi. 10.2337/db12-0797
By:
- Tan, Tricia M.;
- Field, Benjamin C. T.;
- McCullough, Katherine A.;
- Troke, Rachel C.;
- Chambers, Edward S.;
- Salem, Victoria;
- Maffe, Juan Gonzalez;
- Baynes, Kevin C. R.;
- De Silva, Akila;
- Viardot, Alexander;
- Alsafi, Ali;
- Frost, Gary S.;
- Ghatei, Mohammad A.;
- Bloom, Stephen R.
Publication type:
Article

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